piroxicam (BioDeep_00000398951)

Main id: BioDeep_00000002067

 

natural product Chemicals and Drugs


代谢物信息卡片


Piroxicam (Feldene)

化学式: C15H13N3O4S (331.0627)
中文名称: 吡罗昔康
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c(c3)cnc(c3)NC(=O)C(=C(O)1)N(C)S(=O)(=O)c(c2)c(ccc2)1
InChI: InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

描述信息

A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling.
M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AC - Oxicams
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BC - Antiinflammatory agents, non-steroids
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
D000893 - Anti-Inflammatory Agents
D004791 - Enzyme Inhibitors

同义名列表

3 个代谢物同义名

piroxicam; Piroxicam (Feldene); Piroxicam



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, BCL2, CASP3, CAT, CYP2C9, DST, ODC1, PTGS1, PTGS2, VEGFA
Peripheral membrane protein 3 CYP1B1, PTGS1, PTGS2
Endoplasmic reticulum membrane 6 BCL2, CYP1B1, CYP2C9, DST, PTGS1, PTGS2
Nucleus 7 ALB, BCL2, CASP3, DST, MPO, PCNA, VEGFA
cytosol 7 ALB, BCL2, CASP3, CAT, DST, GPT, ODC1
nuclear body 1 PCNA
centrosome 2 ALB, PCNA
nucleoplasm 4 CASP3, DST, MPO, PCNA
Cell membrane 1 DST
Lipid-anchor 1 DST
Cell projection, axon 1 DST
cell cortex 1 DST
cell junction 1 DST
cell surface 1 VEGFA
glutamatergic synapse 1 CASP3
Golgi apparatus 3 ALB, PTGS1, VEGFA
neuronal cell body 1 CASP3
Lysosome 1 MPO
plasma membrane 2 CYP2C9, DST
Membrane 5 BCL2, CAT, CYP1B1, DST, VEGFA
axon 1 DST
caveola 1 PTGS2
extracellular exosome 6 ALB, CAT, GPT, MPO, PCNA, PTGS1
endoplasmic reticulum 4 ALB, BCL2, PTGS2, VEGFA
extracellular space 9 ALB, CRP, IL10, IL17A, IL2, IL4, IL6, MPO, VEGFA
adherens junction 1 VEGFA
mitochondrion 3 BCL2, CAT, CYP1B1
protein-containing complex 4 ALB, BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 5 CAT, CYP1B1, CYP2C9, MPO, PTGS1
Microsome membrane 4 CYP1B1, CYP2C9, PTGS1, PTGS2
postsynaptic density 1 CASP3
Secreted 8 ALB, CRP, IL10, IL17A, IL2, IL4, IL6, VEGFA
extracellular region 10 ALB, CAT, CRP, IL10, IL17A, IL2, IL4, IL6, MPO, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, DST
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 IL17A
Secreted, extracellular space, extracellular matrix 1 VEGFA
actin cytoskeleton 1 DST
Z disc 1 DST
cytoplasmic vesicle 1 DST
microtubule cytoskeleton 1 DST
axon cytoplasm 1 DST
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 DST
focal adhesion 2 CAT, DST
microtubule 1 DST
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
basement membrane 1 DST
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 2 MPO, VEGFA
intermediate filament 1 DST
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 ALB
chromatin 1 PCNA
cell leading edge 1 DST
cell projection 1 DST
cytoskeleton 1 DST
centriole 1 ALB
spindle pole 1 ALB
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
Cytoplasm, cell cortex 1 DST
blood microparticle 1 ALB
nuclear envelope 1 DST
Nucleus envelope 1 DST
Endomembrane system 1 PTGS1
replication fork 1 PCNA
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 DST
stress fiber 1 DST
basal plasma membrane 1 DST
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 3 ALB, IL6, PTGS2
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 2 ALB, VEGFA
azurophil granule lumen 1 MPO
microtubule plus-end 1 DST
nuclear lamina 1 PCNA
phagocytic vesicle lumen 1 MPO
Cytoplasm, cytoskeleton, stress fiber 1 DST
H zone 1 DST
death-inducing signaling complex 1 CASP3
[Isoform 1]: Cytoplasm, cytoskeleton 1 DST
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
hemidesmosome 1 DST
ciliary transition fiber 1 ALB
Cytoplasm, myofibril, sarcomere, H zone 1 DST
[Isoform 2]: Cytoplasm, cytoskeleton 1 DST
[Isoform 6]: Nucleus 1 DST
[Isoform 7]: Cytoplasm, cytoskeleton 1 DST
[Isoform 8]: Cytoplasm, cytoskeleton 1 DST
organelle 1 DST


文献列表

  • Farah Abid, Mohammad Saleem, Talha Jamshaid, Usama Jamshaid, Fadia S Youssef, Reem M Diri, Sameh S Elhady, Mohamed L Ashour. Opuntia monacantha: Validation of the anti-inflammatory and anti-arthritic activity of its polyphenolic rich extract in silico and in vivo via assessment of pro- and anti-inflammatory cytokines. Journal of ethnopharmacology. 2024 May; 326(?):117884. doi: 10.1016/j.jep.2024.117884. [PMID: 38350502]
  • Viviane Lazari Simomura, Daniela Miorando, Beatriz Monteiro Magalhães de Oliveira, Aline Mânica, Lilian Caroline Bohnen, Maike Valentin Buzatto, Francine Mantelli Kunst, Lucas Damo Ansolin, Lincon Bordignon Somensi, Max Vidal Gutiérrez, Larissa Venzon, Thiago Farias de Queiroz E Silva, Luisa Mota da Silva, Walter Antônio Roman Junior. Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats. Journal of ethnopharmacology. 2024 Mar; 321(?):117542. doi: 10.1016/j.jep.2023.117542. [PMID: 38056537]
  • Na Zhu, Xu-Dong Zhu, Yi-Sheng Yang, Fei-Xia Yan, Peng Zhang, Lin-Chun Wan, Yi Wu, Li-Ping Huang. [Different processed products of Polygonati Rhizoma treat Alzheimer's disease in rats: urine metabolomics based on UPLC-Q/TOF-MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Dec; 48(24):6663-6675. doi: 10.19540/j.cnki.cjcmm.20231019.301. [PMID: 38212026]
  • Rahul Maheshwari, Mayank Sharma, Vijay R Chidrawar. Niosomes based formulation containing tenoxicam: A newer solution for the rheumatic diseases. Annales pharmaceutiques francaises. 2023 Nov; ?(?):. doi: 10.1016/j.pharma.2023.10.010. [PMID: 37923009]
  • Abdul Aleem, Bilal Aslam, Muhammad Bilal Alim, Asif Hussain, Muhammad Naeem Faisal, Zia-Ud-Din Sindhu. Phytochemical analysis and gastroprotective effect of Stellaria media (L.) Vill. methanolic extract on piroxicam-induced gastric ulcer in Wistar rats. Pakistan journal of pharmaceutical sciences. 2023 Sep; 36(5):1425-1434. doi: . [PMID: 37869918]
  • Jiayu Zhang, Qing Li, Ziteng Liu, Longshan Zhao. Rapid and sensitive determination of Piroxicam by N-doped carbon dots prepared by plant soot. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2023 May; 299(?):122833. doi: 10.1016/j.saa.2023.122833. [PMID: 37187150]
  • Beatriz Monteiro Magalhães de Oliveira, Patrícia Zanotelli Serpa, Maria Eduarda da Costa Zanatta, Bruna Agnoatto Aires, Amanda Maria Steffler, Lincon Bordignon Somensi, Benhur Judah Cury, Ana Caroline Dos Santos, Larissa Venzon, Thaise Boeing, Luisa Mota da Silva, Walter Antônio Roman Junior. Gastroprotective and gastric healing effects of the aqueous extract of Casearia sylvestris in rodents: Ultrasound, histological and biochemical analyzes. Journal of ethnopharmacology. 2022 Nov; 298(?):115660. doi: 10.1016/j.jep.2022.115660. [PMID: 35995277]
  • Khaoula Bel Haj Ali, Adel Sekma, Saoussen Ben Abdallah, Hajer Yaakoubi, Imen Trabelsi, Nourzed Frikha, Houda Ben Soltane, Mohamed Habib Grissa, Hamdi Boubaker, Mohamed Amine Msolli, Zied Mezgar, Kaouthar Beltaief, Riadh Boukef, Semir Nouira. Analgesic effect of topical piroxicam versus phytotherapy gel in the treatment of acute soft tissues injuries: a randomized controlled non-inferiority study. Pain medicine (Malden, Mass.). 2022 Nov; ?(?):. doi: 10.1093/pm/pnac176. [PMID: 36355573]
  • Ceyda Tuba Sengel-Turk, Erva Ozkan, Filiz Bakar-Ates. Box-Behnken design optimization and in vitro cell based evaluation of piroxicam loaded core-shell type hybrid nanocarriers for prostate cancer. Journal of pharmaceutical and biomedical analysis. 2022 Jul; 216(?):114799. doi: 10.1016/j.jpba.2022.114799. [PMID: 35525111]
  • Moataz B Zewail, Gihan F Asaad, Salma M Swellam, Sama M Abd-Allah, Sahar K Hosny, Salma K Sallah, Jehan E Eissa, Salma S Mohamed, Walaa A El-Dakroury. Design, characterization and in vivo performance of solid lipid nanoparticles (SLNs)-loaded mucoadhesive buccal tablets for efficient delivery of Lornoxicam in experimental inflammation. International journal of pharmaceutics. 2022 Jul; 624(?):122006. doi: 10.1016/j.ijpharm.2022.122006. [PMID: 35820515]
  • Maryam Moallemi Bahmani, Ali Mohammad Haji Shabani, Shayessteh Dadfarnia, Roya Afsharipour. Selective and Sensitive Fluorometric Determination of Piroxicam Based on Nitrogen-doped Graphene Quantum Dots and Gold Nanoparticles Coated with Phenylalanine. Journal of fluorescence. 2022 Jul; 32(4):1337-1346. doi: 10.1007/s10895-022-02907-4. [PMID: 35366163]
  • Nguyen-Thach Tung, Thi-Hoang-Yen Dong, Cao-Son Tran, Thi-Kim-Thuy Nguyen, Sang-Cheol Chi, Danh-Son Dao, Dang-Hoa Nguyen. Integration of lornoxicam nanocrystals into hydroxypropyl methylcellulose-based sustained release matrix to form a novel biphasic release system. International journal of biological macromolecules. 2022 Jun; 209(Pt A):441-451. doi: 10.1016/j.ijbiomac.2022.04.041. [PMID: 35413313]
  • Chang-Keun Cho, Pureum Kang, Hye-Jung Park, Eunvin Ko, Chou Yen Mu, Yun Jeong Lee, Chang-Ik Choi, Hyung Sik Kim, Choon-Gon Jang, Jung-Woo Bae, Seok-Yong Lee. Physiologically based pharmacokinetic (PBPK) modeling of piroxicam with regard to CYP2C9 genetic polymorphism. Archives of pharmacal research. 2022 May; 45(5):352-366. doi: 10.1007/s12272-022-01388-0. [PMID: 35639246]
  • Sabry M El-Bahr, Rabab R Elzoghby, Mohammed A Alfattah, Mahmoud Kandeel, Ahlam F Hamouda. Aqueous Ginger (Zingiber officinale) Extract Ameliorates the Harmful Effects of High-Dose Lornoxicam in Albino Male Rats. BioMed research international. 2022; 2022(?):1546734. doi: 10.1155/2022/1546734. [PMID: 35958816]
  • Nobuaki Ishihama, Seung-Won Choi, Yoshiteru Noutoshi, Ivana Saska, Shuta Asai, Kaori Takizawa, Sheng Yang He, Hiroyuki Osada, Ken Shirasu. Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway. Nature communications. 2021 12; 12(1):7303. doi: 10.1038/s41467-021-27489-w. [PMID: 34911942]
  • Xavier Mas-Orea, Morgane Sebert, Mehdi Benamar, Camille Petitfils, Catherine Blanpied, Abdelhadi Saoudi, Céline Deraison, Frederick Barreau, Nicolas Cenac, Gilles Dietrich. Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice. International journal of molecular sciences. 2021 Jul; 22(14):. doi: 10.3390/ijms22147387. [PMID: 34299013]
  • Nehal Salahuddin, Mohamed Gaber, Sahar Elneanaey, Michael R Snowdon, Mohamed A Abdelwahab. Co-delivery of norfloxacin and tenoxicam in Ag-TiO2/poly(lactic acid) nanohybrid. International journal of biological macromolecules. 2021 Jun; 180(?):771-781. doi: 10.1016/j.ijbiomac.2021.03.033. [PMID: 33705836]
  • Maria Elaine Araruna, Pablo Silva, Maria Almeida, Renaly Rêgo, Raiff Dantas, Hilton Albuquerque, Ingrid Cabral, Nadjaele Apolinário, Francinalva Medeiros, Ana Medeiros, Vanda Santos. Tablet of Spondias mombin L. Developed from Nebulized Extract Prevents Gastric Ulcers in Mice via Cytoprotective and Antisecretory Effects. Molecules (Basel, Switzerland). 2021 Mar; 26(6):. doi: 10.3390/molecules26061581. [PMID: 33809398]
  • Shin-Ichiro Karaki, Ryo Tanaka. Role of PGE2 in colonic motility: PGE2 attenuates spontaneous contractions of circular smooth muscle via EP4 receptors in the rat colon. The journal of physiological sciences : JPS. 2021 Feb; 71(1):8. doi: 10.1186/s12576-021-00791-4. [PMID: 33622238]
  • Mohammad Saleem, Muhammad Asif, Anum Parveen, Hafiza Sidra Yaseen, Malik Saadullah, Asiya Bashir, Jawaria Asif, Mehwish Arif, Ikram Ullah Khan, Rizwan Ullah Khan. Investigation of in vivo anti-inflammatory and anti-angiogenic attributes of coumarin-rich ethanolic extract of Melilotus indicus. Inflammopharmacology. 2021 Feb; 29(1):281-293. doi: 10.1007/s10787-020-00703-9. [PMID: 32297069]
  • Mahmoud H Teaima, Khaled M Abdel-Haleem, Rewan Osama, Mohamed A El-Nabarawi, Osama S Elnahas. A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study. Drug design, development and therapy. 2021; 15(?):4229-4242. doi: 10.2147/dddt.s332729. [PMID: 34675486]
  • Hajra Afeera Hamid, Shahzeb Khan, Syed Muhammad Noor Shah, Muhammad Asghar, Muhammad Shahid, Zahid Hussain, Muhammad Sohail, Barkat Ali Khan, Fazli Amin, Syed Umer Jan, Abdelbary Elhissi, Syed Muhammad Hassan Shah, Muhammad Usman Minhas, Syed Wadood Ali Shah, Naveed Ahmad. Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation. Pakistan journal of pharmaceutical sciences. 2021 Jan; 34(1(Supplementary)):327-335. doi: . [PMID: 34275858]
  • Saud Bawazeer, Dalia Farag A El-Telbany, Majid Mohammad Al-Sawahli, Gamal Zayed, Ahmed Abdallah A Keed, Abdelaziz E Abdelaziz, Doaa H Abdel-Naby. Effect of nanostructured lipid carriers on transdermal delivery of tenoxicam in irradiated rats. Drug delivery. 2020 Dec; 27(1):1218-1230. doi: 10.1080/10717544.2020.1803448. [PMID: 32772730]
  • Roxana Sandulovici, Ion Mircioiu, Hassan Y Aboul-Enein, Mihai Manolache, Constantin Mircioiu, Victor Voicu, Valentina Anuta. Sources of outlier data in the bioanalytical and clinical part of a piroxicam bioequivalence study. International journal of clinical pharmacology and therapeutics. 2020 Nov; 58(11):652-663. doi: 10.5414/cp203794. [PMID: 32870154]
  • M I Oraebosi, G M Good, T Chia, O I Oyeniran. Bombax Costatum extract abrogates piroxicam-mediated hepatic and gastric toxicities in rats. Annales pharmaceutiques francaises. 2020 Nov; 78(6):507-514. doi: 10.1016/j.pharma.2020.06.002. [PMID: 32565156]
  • Edvaldo Balbino Alves Júnior, Rodrigo de Oliveira Formiga, Catarina Alves de Lima Serafim, Maria Elaine Cristina Araruna, Michele Liz de Souza Pessoa, Roseane Carvalho Vasconcelos, Thais Gomes de Carvalho, Tamires Gonçalves de Jesus, Aurigena Antunes Araújo, Raimundo Fernandes de Araujo Junior, Giciane Carvalho Vieira, Marianna Vieira Sobral, Leônia Maria Batista. Estragole prevents gastric ulcers via cytoprotective, antioxidant and immunoregulatory mechanisms in animal models. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Oct; 130(?):110578. doi: 10.1016/j.biopha.2020.110578. [PMID: 32750650]
  • Ahmed Abdeen, Afaf Abdelkader, Dina Elgazzar, Mohamed Aboubakr, Omnia A Abdulah, Khaled Shoghy, Mohamed Abdel-Daim, Hamed A El-Serehy, Agnieszka Najda, Amany El-Mleeh. Coenzyme Q10 supplementation mitigates piroxicam-induced oxidative injury and apoptotic pathways in the stomach, liver, and kidney. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Oct; 130(?):110627. doi: 10.1016/j.biopha.2020.110627. [PMID: 34321156]
  • Jiani Huang, Fang Wen, Wenjie Huang, Yingfeng Bai, Xiaona Lu, Peng Shu. Identification of hub genes and discovery of promising compounds in gastric cancer based on bioinformatics analysis. Biomarkers in medicine. 2020 08; 14(12):1069-1084. doi: 10.2217/bmm-2019-0608. [PMID: 32969243]
  • Ludmila Aricov, Daniel George Angelescu, Adriana Băran, Anca Ruxandra Leontieş, Vlad Tudor Popa, Aurica Precupaş, Romică Sandu, Gabriela Stîngă, Dan-Florin Anghel. Interaction of piroxicam with bovine serum albumin investigated by spectroscopic, calorimetric and computational molecular methods. Journal of biomolecular structure & dynamics. 2020 Jun; 38(9):2659-2671. doi: 10.1080/07391102.2019.1645733. [PMID: 31315508]
  • Gergő Dargó, Dávid Bajusz, Kristóf Simon, Judit Müller, György T Balogh. Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry. 2020 02; 63(4):1763-1774. doi: 10.1021/acs.jmedchem.0c00046. [PMID: 31995375]
  • V V Popov, G N Gildeeva, D V Butuzova, E A Ezhova, A V Belostotskiy, N A Bulanova. [A study of the efficacy and safety of lornoxicam in patients with acute sciatica]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2020; 120(5):42-49. doi: 10.17116/jnevro202012005142. [PMID: 32621467]
  • Lin Zhao, Omer Mustapha, Shumaila Shafique, Talha Jamshaid, Fakhar Ud Din, Yasir Mehmood, Khaleeq Anwer, Qurrat Ul Ain Yousafi, Talib Hussain, Ikram Ullah Khan, Muhammad Usman Ghori, Yasser Shahzad, Abid Mehmood Yousaf. Electrospun Gelatin Nanocontainers for Enhanced Biopharmaceutical Performance of Piroxicam: In Vivo and In Vitro Investigations. International journal of nanomedicine. 2020; 15(?):8819-8828. doi: 10.2147/ijn.s271938. [PMID: 33204090]
  • Sajedeh Salandari, Tahoora Shomali, Najmeh Mosleh, Saeed Nazifi. A comparative study on anti-inflammatory drug combinations in domestic pigeons with experimentally induced acute arthritis. Acta veterinaria Hungarica. 2019 12; 67(4):588-601. doi: 10.1556/004.2019.058. [PMID: 31842592]
  • Zhipei Sang, Keren Wang, Pengfei Zhang, Jian Shi, Wenmin Liu, Zhenghuai Tan. Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease. European journal of medicinal chemistry. 2019 Oct; 180(?):238-252. doi: 10.1016/j.ejmech.2019.07.021. [PMID: 31310916]
  • Zhipei Sang, Keren Wang, Jian Shi, Wenmin Liu, Zhenghuai Tan. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease. European journal of medicinal chemistry. 2019 Sep; 178(?):726-739. doi: 10.1016/j.ejmech.2019.06.026. [PMID: 31229875]
  • Mohammed Gamal, Hazim M Ali, Safwan M Fraihat, T A Seaf Elnasr. Simultaneous determination of piroxicam and norfloxacin in biological fluids by high-performance liquid chromatography with fluorescence detection at zero-order emission mode. Luminescence : the journal of biological and chemical luminescence. 2019 Sep; 34(6):644-650. doi: 10.1002/bio.3648. [PMID: 31184428]
  • Ahmed Abdeen, Omayma A Abou-Zaid, Hussein A Abdel-Maksoud, Mohamed Aboubakr, Afaf Abdelkader, Amany Abdelnaby, Ahmed I Abo-Ahmed, Amany El-Mleeh, Ola Mostafa, Mohamed Abdel-Daim, Lotfi Aleya. Cadmium overload modulates piroxicam-regulated oxidative damage and apoptotic pathways. Environmental science and pollution research international. 2019 Aug; 26(24):25167-25177. doi: 10.1007/s11356-019-05783-x. [PMID: 31256392]
  • David Meriwether, Dawoud Sulaiman, Carmen Volpe, Anna Dorfman, Victor Grijalva, Nasrin Dorreh, R Sergio Solorzano-Vargas, Jifang Wang, Ellen O'Connor, Jeremy Papesh, Muriel Larauche, Hannah Trost, Mayakonda N Palgunachari, G M Anantharamaiah, Harvey R Herschman, Martin G Martin, Alan M Fogelman, Srinivasa T Reddy. Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model. The Journal of clinical investigation. 2019 06; 129(9):3670-3685. doi: 10.1172/jci123700. [PMID: 31184596]
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