Valine (BioDeep_00000398124)

Main id: BioDeep_00000014861

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


poly-l-valine

化学式: C5H11NO2 (117.079)
中文名称: 聚-L-缬氨酸, DL-缬氨酸, 缬氨酸, L-缬氨酸
谱图信息: 最多检出来源 Mus musculus(natural_products) 6.24%

分子结构信息

SMILES: CC(C)C(C(=O)O)N
InChI: InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)

描述信息

A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group.
Acquisition and generation of the data is financially supported by the Max-Planck-Society
L-Valine (Valine) is a new nonlinear semiorganic material[1].
L-Valine (Valine) is a new nonlinear semiorganic material[1].

同义名列表

8 个代谢物同义名

poly-l-valine; DL-Valine; Valine; L-Valine; L-Valine; Valine; Valine; DL-Valine



数据库引用编号

68 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ALB, DAO, JAK2, PRNP, RBMS3, TYR
Peripheral membrane protein 3 DAO, ERVW-1, JAK2
Endoplasmic reticulum membrane 2 CD4, DHCR7
Nucleus 4 ALB, JAK2, RBM10, RBMS3
cytosol 6 ALB, DAO, JAK2, LIF, PRNP, RBMS3
dendrite 1 PRNP
centrosome 1 ALB
nucleoplasm 3 JAK2, RBM10, SLC3A2
Cell membrane 7 CD4, DAO, KCNJ1, PRNP, SLC1A5, SLC3A2, ZP4
Multi-pass membrane protein 3 DHCR7, KCNJ1, SLC1A5
Synapse 1 SLC3A2
cell junction 1 SLC3A2
cell surface 3 C3, PRNP, SLC3A2
glutamatergic synapse 1 JAK2
Golgi apparatus 2 ALB, PRNP
Golgi membrane 1 INS
lysosomal membrane 2 GAA, SLC3A2
postsynapse 2 JAK2, PRNP
Cytoplasm, cytosol 1 DAO
Lysosome 2 GAA, TYR
plasma membrane 12 C3, CD4, DAO, ERVW-1, F9, GAA, JAK2, KCNJ1, PRNP, SLC1A5, SLC3A2, ZP4
presynaptic active zone 1 DAO
terminal bouton 1 PRNP
Membrane 6 DHCR7, GAA, JAK2, PRNP, SLC1A5, SLC3A2
apical plasma membrane 1 SLC3A2
basolateral plasma membrane 1 SLC3A2
caveola 1 JAK2
extracellular exosome 8 ALB, C3, DAO, F9, GAA, PRNP, SLC1A5, SLC3A2
Lysosome membrane 2 GAA, SLC3A2
endoplasmic reticulum 4 AGR3, ALB, DHCR7, PRNP
extracellular space 6 ALB, C3, DAO, F9, INS, LIF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 TYR
bicellular tight junction 1 DAO
mitochondrion 1 PRNP
protein-containing complex 3 ALB, C3, RBM10
intracellular membrane-bounded organelle 4 AGR3, GAA, PRNP, TYR
postsynaptic density 1 PRNP
Single-pass type I membrane protein 4 CD4, ERVW-1, TYR, ZP4
Secreted 6 ALB, C3, DAO, F9, GAA, INS
extracellular region 8 ALB, C3, DAO, F9, GAA, INS, LIF, ZP4
cytoplasmic side of plasma membrane 1 JAK2
Mitochondrion outer membrane 1 PRNP
Single-pass membrane protein 1 PRNP
mitochondrial outer membrane 1 PRNP
Extracellular side 1 DAO
anchoring junction 2 ALB, SLC3A2
nuclear membrane 1 PRNP
external side of plasma membrane 2 CD4, PRNP
nucleolus 1 RBM10
Melanosome membrane 1 TYR
Early endosome 1 CD4
Golgi-associated vesicle 1 TYR
Single-pass type II membrane protein 1 SLC3A2
Apical cell membrane 1 SLC3A2
Membrane raft 3 CD4, JAK2, PRNP
focal adhesion 1 JAK2
Peroxisome 1 DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 2 F9, ZP4
nuclear speck 1 RBM10
nuclear outer membrane 1 DHCR7
ciliary basal body 1 ALB
cell projection 1 DAO
cytoskeleton 1 JAK2
centriole 1 ALB
Secreted, extracellular space 1 DAO
Nucleus, nucleolus 1 RBM10
spindle pole 1 ALB
blood microparticle 2 ALB, C3
Basolateral cell membrane 1 SLC3A2
Lipid-anchor, GPI-anchor 1 PRNP
Endomembrane system 1 JAK2
endosome lumen 2 INS, JAK2
monoatomic ion channel complex 1 KCNJ1
tertiary granule membrane 1 GAA
Melanosome 3 SLC1A5, SLC3A2, TYR
euchromatin 1 JAK2
side of membrane 1 PRNP
basal plasma membrane 2 SLC1A5, SLC3A2
secretory granule lumen 2 C3, INS
Golgi lumen 2 F9, INS
endoplasmic reticulum lumen 5 ALB, C3, CD4, F9, INS
platelet alpha granule lumen 1 ALB
specific granule lumen 1 DAO
extrinsic component of membrane 1 PRNP
transport vesicle 1 INS
azurophil granule membrane 1 GAA
azurophil granule lumen 1 C3
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 CD4
ribonucleoprotein complex 1 RBMS3
extrinsic component of cytoplasmic side of plasma membrane 1 JAK2
ficolin-1-rich granule membrane 1 GAA
[Transmembrane protein]: Cell membrane 1 ERVW-1
[Surface protein]: Cell membrane 1 ERVW-1
extrinsic component of plasma membrane 1 JAK2
granulocyte macrophage colony-stimulating factor receptor complex 1 JAK2
interleukin-12 receptor complex 1 JAK2
interleukin-23 receptor complex 1 JAK2
T cell receptor complex 1 CD4
inclusion body 1 PRNP
amino acid transport complex 1 SLC3A2
apical pole of neuron 1 SLC3A2
autolysosome lumen 1 GAA
egg coat 1 ZP4
ciliary transition fiber 1 ALB
[Processed zona pellucida sperm-binding protein 4]: Zona pellucida 1 ZP4
[Syncytin-1]: Virion 1 ERVW-1


文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Prasanta Ghosh, Arpita Bhoumik, Sudipta Saha, Sandipan Mukherjee, Sarfuddin Azmi, Jimut K Ghosh, Sandhya R Dungdung. Spermicidal efficacy of VRP, a synthetic cationic antimicrobial peptide, inducing apoptosis and membrane disruption. Journal of cellular physiology. 2018 Feb; 233(2):1041-1050. doi: 10.1002/jcp.25958. [PMID: 28409819]
  • Thomas Marcussen, Kjetill S Jakobsen, Jirí Danihelka, Harvey E Ballard, Kim Blaxland, Anne K Brysting, Bengt Oxelman. Inferring species networks from gene trees in high-polyploid North American and Hawaiian violets (Viola, Violaceae). Systematic biology. 2012 Jan; 61(1):107-26. doi: 10.1093/sysbio/syr096. [PMID: 21918178]
  • Jorge Dinamarca, Oksana Shlyk-Kerner, David Kaftan, Eran Goldberg, Alexander Dulebo, Manuel Gidekel, Ana Gutierrez, Avigdor Scherz. Double mutation in photosystem II reaction centers and elevated CO2 grant thermotolerance to mesophilic cyanobacterium. PloS one. 2011; 6(12):e28389. doi: 10.1371/journal.pone.0028389. [PMID: 22216094]
  • Richard J Bloomer, Sara A Williams, Robert E Canale, Tyler M Farney, Mohammad M Kabir. Acute effect of nitric oxide supplement on blood nitrate/nitrite and hemodynamic variables in resistance trained men. Journal of strength and conditioning research. 2010 Oct; 24(10):2587-92. doi: 10.1519/jsc.0b013e3181e382c0. [PMID: 20885188]
  • Abdolmajid Khosravani, Marie-Claire Parker, Roger Parton, John Coote. Formulation of the adenylate cyclase toxin of Bordetella pertussis as protein-coated microcrystals. Vaccine. 2007 May; 25(22):4361-7. doi: 10.1016/j.vaccine.2007.03.035. [PMID: 17434242]
  • Kazuyuki Minagawa, Shuichi Kouzuki, Hiroyoshi Tani, Kikuo Ishii, Tatsuo Tanimoto, Yoshihiro Terui, Toshiyuki Kamigauchi. Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. The Journal of antibiotics. 2002 Mar; 55(3):239-48. doi: 10.7164/antibiotics.55.239. [PMID: 12014438]
  • R G Efremov, D E Nolde, G Vergoten, A S Arseniev. A solvent model for simulations of peptides in bilayers. I. Membrane-promoting alpha-helix formation. Biophysical journal. 1999 May; 76(5):2448-59. doi: 10.1016/s0006-3495(99)77400-x. [PMID: 10233062]