Laudanosine (BioDeep_00000398001)

 

Secondary id: BioDeep_00000002519

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


DL-LAUDANOSINE

化学式: C21H27NO4 (357.194)
中文名称: 劳丹素
谱图信息: 最多检出来源 Viridiplantae(plant) 59.56%

分子结构信息

SMILES: CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC
InChI: InChI=1S/C21H27NO4/c1-22-9-8-15-12-20(25-4)21(26-5)13-16(15)17(22)10-14-6-7-18(23-2)19(11-14)24-3/h6-7,11-13,17H,8-10H2,1-5H3

描述信息

D002491 - Central Nervous System Agents
Annotation level-1
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.628
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.624
Acquisition and generation of the data is financially supported by the Max-Planck-Society
IPB_RECORD: 2441; CONFIDENCE confident structure
DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity[1].
DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity[1].

同义名列表

3 个代谢物同义名

DL-LAUDANOSINE; Laudanosine; Laudanosine



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

52 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ALB, CA1, NT5C2, TERT
Peripheral membrane protein 1 ACHE
Nucleus 3 ACHE, ALB, TERT
cytosol 4 ALB, CA1, NT5C2, TERT
dendrite 1 LRP4
centrosome 1 ALB
nucleoplasm 2 ATP2B1, TERT
Cell membrane 7 ACHE, ATP2B1, GRID1, LRP4, OPRD1, P2RX3, SCN4A
Multi-pass membrane protein 6 ATP2B1, CACNA1I, GRID1, OPRD1, P2RX3, SCN4A
Synapse 2 ACHE, ATP2B1
cell surface 2 ACHE, LRP4
glutamatergic synapse 2 ATP2B1, GRID1
Golgi apparatus 2 ACHE, ALB
neuromuscular junction 2 ACHE, LRP4
neuronal cell body 1 LRP4
postsynapse 1 P2RX3
presynaptic membrane 2 ATP2B1, OPRD1
Cytoplasm, cytosol 1 NT5C2
plasma membrane 11 ACHE, ATP2B1, BCHE, CACNA1I, GRID1, ICAM3, LRP4, OPRD1, P2RX3, SCN4A, TERT
synaptic vesicle membrane 2 ATP2B1, OPRD1
Membrane 8 ACHE, ATP2B1, CACNA1I, ICAM3, LRP4, OPRD1, P2RX3, SCN4A
axon 1 P2RX3
basolateral plasma membrane 1 ATP2B1
extracellular exosome 5 ALB, ATP2B1, CA1, GRID1, ICAM3
endoplasmic reticulum 1 ALB
extracellular space 3 ACHE, ALB, BCHE
perinuclear region of cytoplasm 1 ACHE
Schaffer collateral - CA1 synapse 1 P2RX3
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 1 ATP2B1
postsynaptic density 1 LRP4
Single-pass type I membrane protein 2 ICAM3, LRP4
Secreted 3 ACHE, ALB, BCHE
extracellular region 3 ACHE, ALB, BCHE
Single-pass membrane protein 1 LRP4
hippocampal mossy fiber to CA3 synapse 1 P2RX3
Extracellular side 1 ACHE
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nucleolus 1 TERT
postsynaptic membrane 1 GRID1
GABA-ergic synapse 1 GRID1
mitochondrial nucleoid 1 TERT
basement membrane 1 ACHE
Nucleus, PML body 1 TERT
PML body 1 TERT
lateral plasma membrane 1 ATP2B1
nuclear speck 1 TERT
Postsynaptic cell membrane 1 GRID1
receptor complex 1 P2RX3
neuron projection 1 OPRD1
ciliary basal body 1 ALB
cell projection 1 ATP2B1
centriole 1 ALB
Nucleus, nucleolus 1 TERT
spindle pole 1 ALB
Chromosome, telomere 1 TERT
chromosome, telomeric region 1 TERT
blood microparticle 2 ALB, BCHE
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
Nucleus, nucleoplasm 1 TERT
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
synaptic membrane 1 LRP4
plasma membrane raft 1 LRP4
endoplasmic reticulum lumen 2 ALB, BCHE
platelet alpha granule lumen 1 ALB
axon terminus 1 OPRD1
voltage-gated calcium channel complex 1 CACNA1I
postsynaptic density membrane 2 GRID1, OPRD1
immunological synapse 1 ATP2B1
neuronal dense core vesicle 1 OPRD1
nuclear envelope lumen 1 BCHE
nuclear telomere cap complex 1 TERT
RNA-directed RNA polymerase complex 1 TERT
telomerase catalytic core complex 1 TERT
telomerase holoenzyme complex 1 TERT
TERT-RMRP complex 1 TERT
synaptic cleft 1 ACHE
dendrite membrane 1 OPRD1
voltage-gated sodium channel complex 1 SCN4A
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
spine apparatus 1 OPRD1
ciliary transition fiber 1 ALB


文献列表

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