sulfamethazine (BioDeep_00000397455)
Main id: BioDeep_00000001572
natural product
代谢物信息卡片
化学式: C12H14N4O2S (278.0837)
中文名称: 磺胺二甲嘧啶
谱图信息:
最多检出来源 Homo sapiens(blood) 28.45%
分子结构信息
SMILES: c1(S(Nc2nc(cc(n2)C)C)(=O)=O)ccc(N)cc1
InChI: InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EB - Short-acting sulfonamides
A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8847; ORIGINAL_PRECURSOR_SCAN_NO 8846
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8855; ORIGINAL_PRECURSOR_SCAN_NO 8853
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8878; ORIGINAL_PRECURSOR_SCAN_NO 8876
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8904; ORIGINAL_PRECURSOR_SCAN_NO 8903
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8916; ORIGINAL_PRECURSOR_SCAN_NO 8915
CONFIDENCE standard compound; INTERNAL_ID 1309; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8901; ORIGINAL_PRECURSOR_SCAN_NO 8900
CONFIDENCE standard compound; INTERNAL_ID 4099
CONFIDENCE standard compound; INTERNAL_ID 8503
CONFIDENCE standard compound; EAWAG_UCHEM_ID 181
CONFIDENCE standard compound; INTERNAL_ID 1008
同义名列表
3 个代谢物同义名
sulfamethazine; Sulfadimidin / sulfamethazin; Sulfamethazine
数据库引用编号
46 个数据库交叉引用编号
- ChEBI: CHEBI:102265
- KEGG: C19530
- KEGGdrug: D02436
- PubChem: 5327
- Metlin: METLIN43378
- DrugBank: DB01582
- ChEMBL: CHEMBL446
- MeSH: Sulfamethazine
- CAS: 57-68-1
- MoNA: LU130906
- MoNA: LU130905
- MoNA: LU130904
- MoNA: LU130903
- MoNA: LU130902
- MoNA: LU130901
- MoNA: UF409936
- MoNA: UF409935
- MoNA: SM850301
- MoNA: CCMSLIB00000078582
- MoNA: UF409904
- MoNA: UF409903
- MoNA: UF409902
- MoNA: UF409901
- MoNA: EA018114
- MoNA: EA018113
- MoNA: EA018112
- MoNA: EA018111
- MoNA: EA018110
- MoNA: EA018109
- MoNA: EA018108
- MoNA: EA018107
- MoNA: EA018106
- MoNA: EA018105
- MoNA: EA018104
- MoNA: EA018103
- MoNA: EA018102
- MoNA: EA018101
- MoNA: AU100806
- MoNA: AU100805
- MoNA: AU100804
- MoNA: AU100803
- MoNA: AU100802
- MetaboLights: MTBLC102265
- PubChem: 124490202
- RefMet: Sulfamethazine
- KNApSAcK: 102265
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Xiao-Qiong Zhao, Heng-Hui Zhang, Run-Zhu Zhao, Xin-Mei Zhang. [Effects of Combined Stress of Polyethylene and Sulfamethazine on Seed Germination, Seedling Growth, and Physiological Characteristics of Soybean].
Huan jing ke xue= Huanjing kexue.
2023 Sep; 44(9):5092-5101. doi:
10.13227/j.hjkx.202211033
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Chemosphere.
2023 Jun; 325(?):138362. doi:
10.1016/j.chemosphere.2023.138362
. [PMID: 36905996] - Wei Zhang, Pei-Fang Wang, Qiu-Tong Jin, Bin Hu. [Effects of Sulfamethazine in Soil on Rice Growth].
Huan jing ke xue= Huanjing kexue.
2023 Feb; 44(2):1021-1028. doi:
10.13227/j.hjkx.202203003
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Environmental science & technology.
2022 09; 56(17):12267-12277. doi:
10.1021/acs.est.2c02782
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Water research.
2022 Aug; 221(?):118794. doi:
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The Science of the total environment.
2022 Jul; 828(?):154230. doi:
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Journal of hazardous materials.
2021 09; 417(?):126022. doi:
10.1016/j.jhazmat.2021.126022
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Cell reports.
2021 04; 35(4):109040. doi:
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Environmental research.
2021 04; 195(?):110814. doi:
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International journal of environmental research and public health.
2021 01; 18(3):. doi:
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Chemosphere.
2021 Jan; 263(?):128296. doi:
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The Science of the total environment.
2020 Aug; 731(?):138806. doi:
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Chemosphere.
2020 Jul; 250(?):126161. doi:
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Chemosphere.
2020 Jun; 248(?):126041. doi:
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Applied and environmental microbiology.
2020 03; 86(6):. doi:
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. [PMID: 31862718] - Khang Huynh, Dawn Reinhold. Uptake, translocation, and metabolism of sulfamethazine by Arabidopsis thaliana: distinguishing between phytometabolites and abiotic transformation products in the media.
International journal of phytoremediation.
2020; 22(4):412-419. doi:
10.1080/15226514.2019.1667952
. [PMID: 31549518] - Wen Yang, Tongtong Feng, Markus Flury, Baoguo Li, Jianying Shang. Effect of sulfamethazine on surface characteristics of biochar colloids and its implications for transport in porous media.
Environmental pollution (Barking, Essex : 1987).
2020 Jan; 256(?):113482. doi:
10.1016/j.envpol.2019.113482
. [PMID: 31679872] - Allan J Cessna, Sandra L Kuchta, Marley Waiser, Robert B Brua, Jonathan Bailey. Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands.
Journal of environmental quality.
2020 Jan; 49(1):236-245. doi:
10.1002/jeq2.20034
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Environmental science and pollution research international.
2019 Nov; 26(33):34552-34561. doi:
10.1007/s11356-019-06506-y
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Dapeng Wang, Xian Zhang, Changzhou Yan. Occurrence and removal of sulfonamides and their acetyl metabolites in a biological aerated filter (BAF) of wastewater treatment plant in Xiamen, South China.
Environmental science and pollution research international.
2019 Nov; 26(32):33363-33372. doi:
10.1007/s11356-019-06311-7
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Chemosphere.
2019 Aug; 228(?):556-564. doi:
10.1016/j.chemosphere.2019.04.165
. [PMID: 31055070] - Anne Ostermann, Peter E Mortimer, Rongcai Huang, Lu Ma, Dengpan Bu, Jianchu Xu. Symbiotic Nitrogen Fixation in Soil Contaminated with the Veterinary Antibiotics Oxytetracycline and Sulfamethazine.
Journal of environmental quality.
2019 Jul; 48(4):1067-1073. doi:
10.2134/jeq2019.01.0021
. [PMID: 31589684] - Surased Suraritdechachai, Chayan Charoenpakdee, Iain Young, Simon Maher, Tirayut Vilaivan, Thanit Praneenararat. Rapid Detection of the Antibiotic Sulfamethazine in Pig Body Fluids by Paper Spray Mass Spectrometry.
Journal of agricultural and food chemistry.
2019 Mar; 67(10):3055-3061. doi:
10.1021/acs.jafc.9b00500
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Journal of hazardous materials.
2019 Feb; 364(?):663-670. doi:
10.1016/j.jhazmat.2018.10.045
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International journal of phytoremediation.
2019; 21(11):1104-1111. doi:
10.1080/15226514.2019.1606782
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Journal of environmental sciences (China).
2019 Jan; 75(?):54-63. doi:
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Biomaterials science.
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Bioresource technology.
2018 Jan; 248(Pt B):36-43. doi:
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Human & experimental toxicology.
2018 Jan; 37(1):61-68. doi:
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Environmental pollution (Barking, Essex : 1987).
2017 Dec; 231(Pt 1):829-836. doi:
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Environmental technology.
2017 Nov; 38(21):2684-2690. doi:
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Plant physiology.
2017 Aug; 174(4):2146-2165. doi:
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Environmental pollution (Barking, Essex : 1987).
2017 Feb; 221(?):266-275. doi:
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Bioresource technology.
2016 Nov; 219(?):687-693. doi:
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Bulletin of environmental contamination and toxicology.
2016 Oct; 97(4):528-35. doi:
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Ecotoxicology and environmental safety.
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Analytical chemistry.
2015 Jun; 87(12):6212-9. doi:
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Journal of hazardous materials.
2015 Jun; 290(?):43-50. doi:
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Journal of veterinary pharmacology and therapeutics.
2014 Dec; 37(6):531-41. doi:
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Chemosphere.
2014 Sep; 111(?):500-4. doi:
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Journal of environmental management.
2014 Aug; 141(?):95-103. doi:
10.1016/j.jenvman.2014.02.030
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Biosensors & bioelectronics.
2014 Jul; 57(?):77-84. doi:
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Fish physiology and biochemistry.
2013 Oct; 39(5):1239-51. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
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The Science of the total environment.
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