Sinigrin (BioDeep_00000003569)

 

Secondary id: BioDeep_00001870522

natural product human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


{[(e)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulphanyl}but-3-en-1-ylidene)amino]oxy}sulphonic acid

化学式: C10H17NO9S2 (359.0345)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 13.01%

分子结构信息

SMILES: C=CC/C(=N\OS(=O)(=O)O)/S[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O
InChI: InChI=1S/C10H17NO9S2/c1-2-3-6(11-20-22(16,17)18)21-10-9(15)8(14)7(13)5(4-12)19-10/h2,5,7-10,12-15H,1,3-4H2,(H,16,17,18)/t5-,7-,8+,9-,10+/m1/s1

描述信息

Sinigrin is found in brassicas. Sinigrin is isolated from seeds of black mustard (Brassica nigra) and cabbage, as K salt. Sinigrin is present in many crucifers, major glucosinolate in Brussels sprouts (Brassica oleraceae).
Sinigrin is isolated from seeds of black mustard (Brassica nigra) and cabbage, as a K salt. It is found in many crucifers, major glucosinolate in Brussels sprouts (Brassica oleraceae).
Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

16 个代谢物同义名

{[(e)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulphanyl}but-3-en-1-ylidene)amino]oxy}sulphonic acid; {[(E)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}but-3-en-1-ylidene)amino]oxy}sulfonic acid; {[(e)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulphanyl}but-3-en-1-ylidene)amino]oxy}sulphonate; [(E)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}but-3-en-1-ylidene)amino]oxysulfonic acid; {[(e)-(1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}but-3-en-1-ylidene)amino]oxy}sulfonate; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] N-sulfooxybut-3-enimidothioate; 1-thio-b-D-Glucopyranose 1-[N-(sulfooxy)-3-butenimidate], 9ci; sinigrin, monopotassium salt; 2-Phenylethyl glucosinolate; 2-Propenyl glucosinolate; 2-Propenyl (sinigrin); Allyl glucosinolate; Myronic acid; myronate; Sinigrin; Sinigrin



数据库引用编号

31 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

35 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 17 ANXA5, BCL2, CASP3, CAT, CDK2, CDK4, CDKN1A, HPGDS, IL18, MAPK14, MAPK8, MTOR, NLRP3, NQO1, PIK3CA, PTGS2, TP53
Peripheral membrane protein 3 ANXA5, MTOR, PTGS2
Endoplasmic reticulum membrane 3 BCL2, MTOR, PTGS2
Nucleus 11 BCL2, CASP3, CDK2, CDK4, CDKN1A, MAPK14, MAPK8, MTOR, NLRP3, NQO1, TP53
cytosol 17 ANXA5, BCL2, CASP3, CAT, CDK2, CDK4, CDKN1A, GLS, HPGDS, IL18, MAPK14, MAPK8, MTOR, NLRP3, NQO1, PIK3CA, TP53
dendrite 2 MTOR, NQO1
nuclear body 1 CDKN1A
phagocytic vesicle 1 MTOR
centrosome 2 CDK2, TP53
nucleoplasm 9 CASP3, CDK2, CDK4, CDKN1A, HPGDS, MAPK14, MAPK8, MTOR, TP53
Cell membrane 1 TNF
Cytoplasmic side 1 MTOR
lamellipodium 1 PIK3CA
Golgi apparatus membrane 2 MTOR, NLRP3
Synapse 3 GLS, MAPK8, NQO1
cell surface 1 TNF
glutamatergic synapse 2 CASP3, MAPK14
Golgi membrane 2 MTOR, NLRP3
lysosomal membrane 1 MTOR
neuronal cell body 3 CASP3, NQO1, TNF
sarcolemma 1 ANXA5
Cytoplasm, cytosol 4 GLS, IL18, NLRP3, NQO1
Lysosome 1 MTOR
endosome 1 CDK2
plasma membrane 2 PIK3CA, TNF
Membrane 7 ANXA5, BCL2, CAT, MTOR, NLRP3, NQO1, TP53
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 2 ANXA5, CAT
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 BCL2, NLRP3, PTGS2, TP53
extracellular space 3 CCL2, IL18, TNF
perinuclear region of cytoplasm 2 CDKN1A, PIK3CA
bicellular tight junction 1 CDK4
intercalated disc 1 PIK3CA
mitochondrion 6 BCL2, CAT, GLS, MAPK14, NLRP3, TP53
protein-containing complex 5 BCL2, CAT, CDKN1A, PTGS2, TP53
intracellular membrane-bounded organelle 2 CAT, HPGDS
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 3 CCL2, IL18, NLRP3
extracellular region 7 ANXA5, CAT, CCL2, IL18, MAPK14, NLRP3, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 3 CAT, GLS, TP53
transcription regulator complex 3 CDK2, CDK4, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 CDK2, TP53
Nucleus membrane 2 BCL2, CDK4
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, CDK4
external side of plasma membrane 2 ANXA5, TNF
nucleolus 3 CDK4, CDKN1A, TP53
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
focal adhesion 2 ANXA5, CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
collagen-containing extracellular matrix 1 ANXA5
nuclear speck 1 MAPK14
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
chromatin 2 CDK4, TP53
phagocytic cup 1 TNF
[Isoform 1]: Mitochondrion 1 GLS
spindle pole 1 MAPK14
chromosome, telomeric region 1 CDK2
site of double-strand break 1 TP53
nuclear envelope 2 CDK2, MTOR
Endomembrane system 2 MTOR, NLRP3
microtubule organizing center 1 NLRP3
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 2 CAT, MAPK14
endoplasmic reticulum lumen 1 PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
male germ cell nucleus 1 CDK2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
vesicle membrane 1 ANXA5
Cajal body 1 CDK2
[Isoform 1]: Nucleus 1 TP53
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
condensed chromosome 1 CDK2
[Isoform 3]: Mitochondrion 1 GLS
Cytoplasmic vesicle, phagosome 1 MTOR
Nucleus, Cajal body 1 CDK2
X chromosome 1 CDK2
Y chromosome 1 CDK2
cyclin-dependent protein kinase holoenzyme complex 3 CDK2, CDK4, CDKN1A
[Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix 1 GLS
[Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix 1 GLS
cyclin E1-CDK2 complex 1 CDK2
cyclin E2-CDK2 complex 1 CDK2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
cyclin D1-CDK4 complex 1 CDK4
cyclin D2-CDK4 complex 1 CDK4
cyclin D3-CDK4 complex 1 CDK4
PCNA-p21 complex 1 CDKN1A
cyclin A2-CDK2 complex 1 CDK2
cyclin A1-CDK2 complex 1 CDK2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Azra Đulović, Franko Burčul, Vedrana Čikeš Čulić, Patrick Rollin, Ivica Blažević. Glucosinolates and Cytotoxic Activity of Collard Volatiles Obtained Using Microwave-Assisted Extraction. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041657. [PMID: 36838645]
  • Laura Plaza-Vinuesa, Oswaldo Hernandez-Hernandez, Ana Sánchez-Arroyo, José M Cumella, Nieves Corzo, Ana M Muñoz-Labrador, F Javier Moreno, Blanca de Las Rivas, Rosario Muñoz. Deciphering the Myrosinase-like Activity of Lactiplantibacillus plantarum WCFS1 among GH1 Family Glycoside Hydrolases. Journal of agricultural and food chemistry. 2022 Dec; 70(49):15531-15538. doi: 10.1021/acs.jafc.2c06240. [PMID: 36454042]
  • Yan Chen, Pei-Chao Wang, Shuai-Shuai Zhang, Jun Yang, Guo-Cheng Li, Ling-Qiao Huang, Chen-Zhu Wang. Functional analysis of a bitter gustatory receptor highly expressed in the larval maxillary galea of Helicoverpa armigera. PLoS genetics. 2022 10; 18(10):e1010455. doi: 10.1371/journal.pgen.1010455. [PMID: 36206313]
  • Shuqin Li, Jiawen Lin, Jiaofei Wei, Lingzhi Zhou, Peishun Wang. Sinigrin Impedes the Breast Cancer Cell Growth through the Inhibition of PI3K/AKT/mTOR Phosphorylation-Mediated Cell Cycle Arrest. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2022; 41(3):33-43. doi: 10.1615/jenvironpatholtoxicoloncol.2022041136. [PMID: 35993954]
  • Neha Sylvia Walter, Varun Gorki, Monika Chauhan, Neelima Dhingra, Sukhbir Kaur. Sinigrin in combination with artesunate provides protection against lethal murine malaria via falcipain-3 inhibition and immune modulation. International immunopharmacology. 2021 Dec; 101(Pt A):108320. doi: 10.1016/j.intimp.2021.108320. [PMID: 34741871]
  • Cong Cong, Xiaohong Yuan, Ying Hu, Wenjing Chen, Yong Wang, Lei Tao. Sinigrin attenuates angiotensin II‑induced kidney injury by inactivating nuclear factor‑κB and extracellular signal‑regulated kinase signaling in vivo and in vitro. International journal of molecular medicine. 2021 Aug; 48(2):. doi: 10.3892/ijmm.2021.4994. [PMID: 34278443]
  • Jun Yang, Hao Guo, Nan-Ji Jiang, Rui Tang, Guo-Cheng Li, Ling-Qiao Huang, Joop J A van Loon, Chen-Zhu Wang. Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae. PLoS genetics. 2021 07; 17(7):e1009527. doi: 10.1371/journal.pgen.1009527. [PMID: 34264948]
  • Hee-Yeon Kwon, Sun-Il Choi, Xionggao Han, Xiao Men, Gill-Woong Jang, Ye-Eun Choi, Ok-Hwan Lee. Antiobesity effect of Brassica juncea cultivated in Jeongseon with optimized sinigrin content using 3T3-L1 adipocytes. Journal of food biochemistry. 2021 04; 45(4):e13650. doi: 10.1111/jfbc.13650. [PMID: 33576517]
  • Jinghua Yang, Zhangping Li, Jinmin Lian, Guoning Qi, Pibiao Shi, Jiawei He, Zhongyuan Hu, Mingfang Zhang. Brassicaceae transcriptomes reveal convergent evolution of super-accumulation of sinigrin. Communications biology. 2020 12; 3(1):779. doi: 10.1038/s42003-020-01523-x. [PMID: 33328568]
  • Jie Hu, Jin-Jian Yang, Bai-Ming Liu, Hong-Ying Cui, You-Jun Zhang, Xiao-Guo Jiao. Feeding behavior explains the different effects of cabbage on MEAM1 and MED cryptic species of Bemisia tabaci. Insect science. 2020 Dec; 27(6):1276-1284. doi: 10.1111/1744-7917.12739. [PMID: 31769205]
  • Jilan Nazeam, Esraa Z Mohammed, Mariam Raafat, Mariam Houssein, Asmaa Elkafoury, Dina Hamdy, Lina Jamil. Based on Principles and Insights of COVID-19 Epidemiology, Genome Sequencing, and Pathogenesis: Retrospective Analysis of Sinigrin and ProlixinRX (Fluphenazine) Provides Off-Label Drug Candidates. SLAS discovery : advancing life sciences R & D. 2020 12; 25(10):1123-1140. doi: 10.1177/2472555220950236. [PMID: 32804597]
  • Anroop B Nair, Dipal Gandhi, Snehal S Patel, Mohamed A Morsy, Bapi Gorain, Mahesh Attimarad, Jigar N Shah. Development of HPLC Method for Quantification of Sinigrin from Raphanus sativus Roots and Evaluation of Its Anticancer Potential. Molecules (Basel, Switzerland). 2020 Oct; 25(21):. doi: 10.3390/molecules25214947. [PMID: 33114598]
  • Maria Fernanda Lopez-Rodriguez, Nadia Cymbaluk, Tasha Epp, Bernard Laarveld, Elena Carolina Serrano Recalde, Elemir Simko, Claire Card. Effects of the Glucosinolate Sinigrin in Combination With a Noniodine Supplemented Diet on Serum Iodine and Thyroid Hormone Concentrations in Nonpregnant Mares. Journal of equine veterinary science. 2020 08; 91(?):103110. doi: 10.1016/j.jevs.2020.103110. [PMID: 32684255]
  • Leanne E Mocniak, Kyle Elkin, J Martin Bollinger. Lifetimes of the Aglycone Substrates of Specifier Proteins, the Autonomous Iron Enzymes That Dictate the Products of the Glucosinolate-Myrosinase Defense System in Brassica Plants. Biochemistry. 2020 07; 59(26):2432-2441. doi: 10.1021/acs.biochem.0c00358. [PMID: 32516526]
  • Nur Alim Bahmid, Laurens Pepping, Matthijs Dekker, Vincenzo Fogliano, Jenneke Heising. Using particle size and fat content to control the release of Allyl isothiocyanate from ground mustard seeds for its application in antimicrobial packaging. Food chemistry. 2020 Mar; 308(?):125573. doi: 10.1016/j.foodchem.2019.125573. [PMID: 31639598]
  • Diana L Zuluaga, Neil S Graham, Annett Klinder, A E Elaine van Ommen Kloeke, Angelo R Marcotrigiano, Carol Wagstaff, Ruud Verkerk, Gabriella Sonnante, Mark G M Aarts. Overexpression of the MYB29 transcription factor affects aliphatic glucosinolate synthesis in Brassica oleracea. Plant molecular biology. 2019 Sep; 101(1-2):65-79. doi: 10.1007/s11103-019-00890-2. [PMID: 31190320]
  • Ji H Lee, Jeongyeo Lee, HyeRan Kim, Won B Chae, Sun-Ju Kim, Yong P Lim, Man-Ho Oh. Brassinosteroids regulate glucosinolate biosynthesis in Arabidopsis thaliana. Physiologia plantarum. 2018 Aug; 163(4):450-458. doi: 10.1111/ppl.12691. [PMID: 29315590]
  • Hee-Weon Lee, Dong-Kwon Rhee, Byung-Oh Kim, Suhkneung Pyo. Inhibitory effect of sinigrin on adipocyte differentiation in 3T3-L1 cells: Involvement of AMPK and MAPK pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Jun; 102(?):670-680. doi: 10.1016/j.biopha.2018.03.124. [PMID: 29604586]
  • Fangfang Huang, Richard Lankau, Shaolin Peng. Coexistence via coevolution driven by reduced allelochemical effects and increased tolerance to competition between invasive and native plants. The New phytologist. 2018 04; 218(1):357-369. doi: 10.1111/nph.14937. [PMID: 29205373]
  • Aniruddha R Agnihotri, Chaitanya V Hulagabali, Anmol S Adhav, Rakesh S Joshi. Mechanistic insight in potential dual role of sinigrin against Helicoverpa armigera. Phytochemistry. 2018 Jan; 145(?):121-127. doi: 10.1016/j.phytochem.2017.10.014. [PMID: 29126020]
  • Yeon Jeong Jang, Bongkyun Park, Hee-Weon Lee, Hye Jin Park, Hyun Jung Koo, Byung Oh Kim, Eun-Hwa Sohn, Sung Hee Um, Suhkneung Pyo. Sinigrin attenuates the progression of atherosclerosis in ApoE-/- mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression. Chemico-biological interactions. 2017 Jun; 272(?):28-36. doi: 10.1016/j.cbi.2017.05.006. [PMID: 28483571]
  • Felix Hirschmann, Florian Krause, Petra Baruch, Igor Chizhov, Jonathan Wolf Mueller, Dietmar J Manstein, Jutta Papenbrock, Roman Fedorov. Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism. Scientific reports. 2017 06; 7(1):4160. doi: 10.1038/s41598-017-04539-2. [PMID: 28646214]
  • Alessandra Ferramosca, Mariangela Di Giacomo, Vincenzo Zara. Antioxidant dietary approach in treatment of fatty liver: New insights and updates. World journal of gastroenterology. 2017 Jun; 23(23):4146-4157. doi: 10.3748/wjg.v23.i23.4146. [PMID: 28694655]
  • Sabine Montaut, Benjamin S Guido, Claude Grison, Patrick Rollin. Identification of Glucosinolates in Seeds of Three Brassicaceae Species Known to Hyperaccumulate Heavy Metals. Chemistry & biodiversity. 2017 Mar; 14(3):. doi: 10.1002/cbdv.201600311. [PMID: 27981800]
  • Saurabh Awasthi, N T Saraswathi. Elucidating the molecular interaction of sinigrin, a potent anticancer glucosinolate from cruciferous vegetables with bovine serum albumin: effect of methylglyoxal modification. Journal of biomolecular structure & dynamics. 2016 Oct; 34(10):2224-32. doi: 10.1080/07391102.2015.1110835. [PMID: 26488200]
  • Tarandeep Kaur, Rohini Bhat, Manu Khajuria, Ruchika Vyas, Anika Kumari, Gireesh Nadda, Ram Vishwakarma, Dhiraj Vyas. Dynamics of glucosinolate-myrosinase system during Plutella xylostella interaction to a novel host Lepidium latifolium L. Plant science : an international journal of experimental plant biology. 2016 Sep; 250(?):1-9. doi: 10.1016/j.plantsci.2016.05.012. [PMID: 27457978]
  • Arif Hasan Khan Robin, Go-Eun Yi, Rawnak Laila, Kiwoung Yang, Jong-In Park, Hye Ran Kim, Ill-Sup Nou. Expression Profiling of Glucosinolate Biosynthetic Genes in Brassica oleracea L. var. capitata Inbred Lines Reveals Their Association with Glucosinolate Content. Molecules (Basel, Switzerland). 2016 Jun; 21(6):. doi: 10.3390/molecules21060787. [PMID: 27322230]
  • Sándor Gonda, Attila Kiss-Szikszai, Zsolt Szűcs, Nhat Minh Nguyen, Gábor Vasas. Myrosinase Compatible Simultaneous Determination of Glucosinolates and Allyl Isothiocyanate by Capillary Electrophoresis Micellar Electrokinetic Chromatography (CE-MEKC). Phytochemical analysis : PCA. 2016 May; 27(3-4):191-8. doi: 10.1002/pca.2615. [PMID: 27313156]
  • X G Wang, X W Gao, P Liang, X Y Shi, D L Song. Induction of Cytochrome P450 Activity by the Interaction of Chlorantraniliprole and Sinigrin in the Spodoptera exigua (Lepidoptera: Noctuidae). Environmental entomology. 2016 Apr; 45(2):500-7. doi: 10.1093/ee/nvw007. [PMID: 26916517]
  • Saurabh Awasthi, N T Saraswathi. Sinigrin, a major glucosinolate from cruciferous vegetables restrains non-enzymatic glycation of albumin. International journal of biological macromolecules. 2016 Feb; 83(?):410-5. doi: 10.1016/j.ijbiomac.2015.11.019. [PMID: 26571343]
  • Manisha Sharma, Arundhati Mukhopadhyay, Vibha Gupta, Deepak Pental, Akshay K Pradhan. BjuB.CYP79F1 Regulates Synthesis of Propyl Fraction of Aliphatic Glucosinolates in Oilseed Mustard Brassica juncea: Functional Validation through Genetic and Transgenic Approaches. PloS one. 2016; 11(2):e0150060. doi: 10.1371/journal.pone.0150060. [PMID: 26919200]
  • Nicole A Goodey, Hannah V Florance, Nicholas Smirnoff, Dave J Hodgson. Aphids Pick Their Poison: Selective Sequestration of Plant Chemicals Affects Host Plant Use in a Specialist Herbivore. Journal of chemical ecology. 2015 Oct; 41(10):956-64. doi: 10.1007/s10886-015-0634-2. [PMID: 26411571]
  • Samantha L Davis, Tina Frisch, Nanna Bjarnholt, Don Cipollini. How Does Garlic Mustard Lure and Kill the West Virginia White Butterfly?. Journal of chemical ecology. 2015 Oct; 41(10):948-55. doi: 10.1007/s10886-015-0633-3. [PMID: 26399433]
  • Krista M Lessner, M Denise Dearing, Ido Izhaki, Michal Samuni-Blank, Zeev Arad, William H Karasov. Small intestinal hydrolysis of plant glucosides: higher glucohydrolase activities in rodents than passerine birds. The Journal of experimental biology. 2015 Sep; 218(Pt 17):2666-9. doi: 10.1242/jeb.121970. [PMID: 26113142]
  • María-Dolores Lozano-Baena, Inmaculada Tasset, Sara Obregón-Cano, Antonio de Haro-Bailon, Andrés Muñoz-Serrano, Ángeles Alonso-Moraga. Antigenotoxicity and Tumor Growing Inhibition by Leafy Brassica carinata and Sinigrin. Molecules (Basel, Switzerland). 2015 Aug; 20(9):15748-65. doi: 10.3390/molecules200915748. [PMID: 26343628]
  • Roniele P Cordeiro, Juan H Doria, George G Zhanel, Richard Sparling, Richard A Holley. Role of glycoside hydrolase genes in sinigrin degradation by E. coli O157:H7. International journal of food microbiology. 2015 Jul; 205(?):105-11. doi: 10.1016/j.ijfoodmicro.2015.04.008. [PMID: 25897994]
  • Anika E Wagner, Christine Sturm, Stefanie Piegholdt, Insa M A Wolf, Tuba Esatbeyoglu, Gina Rosalinda De Nicola, Renato Iori, Gerald Rimbach. Myrosinase-treated glucoerucin is a potent inducer of the Nrf2 target gene heme oxygenase 1--studies in cultured HT-29 cells and mice. The Journal of nutritional biochemistry. 2015 Jun; 26(6):661-6. doi: 10.1016/j.jnutbio.2015.01.004. [PMID: 25776458]
  • Bruno M Ngala, Patrick P J Haydock, Simon Woods, Matthew A Back. Biofumigation with Brassica juncea, Raphanus sativus and Eruca sativa for the management of field populations of the potato cyst nematode Globodera pallida. Pest management science. 2015 May; 71(5):759-69. doi: 10.1002/ps.3849. [PMID: 24965697]
  • Amin N Olaimat, Babak Sobhi, Richard A Holley. Influence of temperature, glucose, and iron on sinigrin degradation by Salmonella and Listeria monocytogenes. Journal of food protection. 2014 Dec; 77(12):2133-8. doi: 10.4315/0362-028x.jfp-14-210. [PMID: 25474062]
  • Inna E Popova, Matthew J Morra. Simultaneous quantification of sinigrin, sinalbin, and anionic glucosinolate hydrolysis products in Brassica juncea and Sinapis alba seed extracts using ion chromatography. Journal of agricultural and food chemistry. 2014 Nov; 62(44):10687-93. doi: 10.1021/jf503755m. [PMID: 25314611]
  • Tina Frisch, Niels Agerbirk, Samantha Davis, Don Cipollini, Carl Erik Olsen, Mohammed Saddik Motawia, Nanna Bjarnholt, Birger Lindberg Møller. Glucosinolate-related glucosides in Alliaria petiolata: sources of variation in the plant and different metabolism in an adapted specialist herbivore, Pieris rapae. Journal of chemical ecology. 2014 Oct; 40(10):1063-79. doi: 10.1007/s10886-014-0509-y. [PMID: 25308480]
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