3'-AMP (BioDeep_00000002935)

 

Secondary id: BioDeep_00000398686

natural product human metabolite Endogenous


代谢物信息卡片


{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid

化学式: C10H14N5O7P (347.0631)
中文名称: 腺苷3-单磷酸酯
谱图信息: 最多检出来源 Homo sapiens(otcml) 6.47%

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c(N)ncnc23)O1)O)OP(=O)(O)O)O
InChI: InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

描述信息

Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2-, 3-, or 5-position. 3-AMP has been identified in the human placenta (PMID: 32033212).
Adenylic acid. Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2-, 3-, or 5-position. [HMDB]
Acquisition and generation of the data is financially supported in part by CREST/JST.
CONFIDENCE standard compound; ML_ID 11

同义名列表

47 个代谢物同义名

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid; [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate; Adenosine 3-monophosphate From Yeast; Dipotassium, adenosine phosphate; Phosphate dipotassium, adenosine; 3-Adenosine monophosphoric acid; Adenosine 3-monophosphoric acid; Adenosine-3-monophosphoric acid; Adenosine phosphate dipotassium; Disodium, adenosine phosphate; Phosphate disodium, adenosine; Adenosine phosphate disodium; Adenosine 3-phosphoric acid; monoPhosphate, 2-adenosine; Adenosine-3-monophosphate; Adenosine 3-monophosphate; 2 Adenosine monophosphate; 2-Adenosine monophosphate; 3-Adenosine monophosphate; Adenosine monophosphate; 5-Phosphate, adenosine; Adenosine 2 phosphate; Adenosine 2-phosphate; Adenosine-3-phosphate; AMP 3-Phosphoric acid; Adenosine 3 phosphate; Adenosine 3-phosphate; Adenosine 5 phosphate; Adenosine 5-phosphate; Yeast adenylic acid; Acid, 5-adenylic; Synadenylic acid; Acid, 2-adenylic; AMP 3-Phosphate; 5 Adenylic acid; 2-Adenylic acid; 5-Adenylic acid; 3-Adenylic acid; 2 Adenylic acid; Adenylic acid; Synadenylate; 3-Adenylate; Phosphaden; 3-AMP; 2-AMP; AMP; 3'-AMP



数据库引用编号

32 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

41 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(40)

PharmGKB(0)

37 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ADA, ITPR3, PNPT1, PRKX, PTPRF, SULT1A1, SULT1E1, SULT2A1
Peripheral membrane protein 2 ADA, PNPT1
Endoplasmic reticulum membrane 4 DHH, HSP90B1, ITPR3, PNPT1
Nucleus 3 HSP90B1, PRKX, TRIM33
cytosol 10 ADA, GPT, HSP90B1, NT5E, PAPSS1, PAPSS2, PNPT1, SULT1A1, SULT1E1, SULT2A1
dendrite 1 P2RY1
nucleoplasm 5 ATP2B1, ITPR3, NT5E, PRKX, TRIM33
Cell membrane 6 ADA, ATP2B1, DHH, NT5E, P2RY1, P2RY6
Lipid-anchor 1 DHH
Multi-pass membrane protein 5 ATP2B1, ITPR3, NNT, P2RY1, P2RY6
Golgi apparatus membrane 1 DHH
Synapse 1 ATP2B1
cell junction 1 ADA
cell surface 3 ADA, NT5E, P2RY1
glutamatergic synapse 2 ATP2B1, P2RY1
Golgi membrane 1 DHH
mitochondrial inner membrane 1 NNT
neuronal cell body 2 ITPR3, PTPRF
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 SULT1E1
Lysosome 1 ADA
plasma membrane 9 ADA, ATP2B1, DHH, GCG, ITPR3, NT5E, P2RY1, P2RY6, PTPRF
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ADA, ATP2B1, HSP90B1, ITPR3, NNT, NT5E, PTPRF
apical plasma membrane 2 P2RY1, P2RY6
basolateral plasma membrane 3 ATP2B1, P2RY1, P2RY6
brush border 1 ITPR3
extracellular exosome 5 ATP2B1, GPT, HSP90B1, NT5E, PTPRF
endoplasmic reticulum 2 HSP90B1, ITPR3
extracellular space 2 DHH, GCG
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 2 NNT, PNPT1
protein-containing complex 1 HSP90B1
intracellular membrane-bounded organelle 1 ATP2B1
postsynaptic density 1 P2RY1
Secreted 2 DHH, GCG
extracellular region 2 GCG, HSP90B1
Single-pass membrane protein 1 PTPRF
Mitochondrion matrix 1 PNPT1
mitochondrial matrix 1 PNPT1
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 SULT1E1
external side of plasma membrane 2 ADA, NT5E
nucleolus 1 ITPR3
midbody 1 HSP90B1
apical part of cell 1 ITPR3
postsynaptic membrane 1 P2RY1
presynaptic active zone membrane 1 P2RY1
Mitochondrion inner membrane 1 NNT
Matrix side 1 NNT
focal adhesion 1 HSP90B1
sarcoplasmic reticulum 1 ITPR3
Mitochondrion intermembrane space 1 PNPT1
mitochondrial intermembrane space 1 PNPT1
collagen-containing extracellular matrix 1 HSP90B1
lateral plasma membrane 1 ATP2B1
nuclear outer membrane 1 ITPR3
receptor complex 1 ITPR3
neuron projection 1 PTPRF
cilium 1 P2RY1
chromatin 1 TRIM33
cell projection 1 ATP2B1
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 NT5E
Melanosome 1 HSP90B1
[Sonic hedgehog protein]: Endoplasmic reticulum membrane 1 DHH
[Protein hedgehog N-product]: Cell membrane 1 DHH
respiratory chain complex 1 NNT
Presynaptic cell membrane 1 ATP2B1
cell body 1 P2RY1
side of membrane 1 NT5E
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 GCG
secretory granule membrane 1 ITPR3
endoplasmic reticulum lumen 2 GCG, HSP90B1
immunological synapse 1 ATP2B1
Sarcoplasmic reticulum lumen 1 HSP90B1
platelet dense tubular network membrane 1 ITPR3
[Desert hedgehog protein N-product]: Cell membrane 1 DHH
[Desert hedgehog protein]: Endoplasmic reticulum membrane 1 DHH
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
endocytic vesicle lumen 1 HSP90B1
ribosome 1 PNPT1
[Glucagon-like peptide 1]: Secreted 1 GCG
transport vesicle membrane 1 ITPR3
catalytic complex 1 PNPT1
endoplasmic reticulum chaperone complex 1 HSP90B1
photoreceptor ribbon synapse 1 ATP2B1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
mitochondrial degradosome 1 PNPT1


文献列表

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  • Ling Lin, Shumin Han, Zhihua Gong, Furong Ding, Zhonghua Liu, Wenjun Xiao. L-Theanine attenuates heat stress-induced proteotoxicity and alterations in carbohydrate and lipid metabolism via heat shock factor 1. Food & function. 2023 Jun; ?(?):. doi: 10.1039/d3fo01001e. [PMID: 37338809]
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  • George Kogkos, Foteini Gkartziou, Spyridon Mourtas, Kostas K Barlos, Pavlos Klepetsanis, Kleomenis Barlos, Sophia G Antimisiaris. Liposomal Entrapment or Chemical Modification of Relaxin2 for Prolongation of Its Stability and Biological Activity. Biomolecules. 2022 09; 12(10):. doi: 10.3390/biom12101362. [PMID: 36291571]
  • Hidetoshi Urakawa, Michael A Kratz, Taylor L Hancock, Rick A Armstrong. QT-AMP: Sequencing PCR amplicons from Quanti-Tray wells to analyze enterococci communities. The Science of the total environment. 2022 Sep; 839(?):156188. doi: 10.1016/j.scitotenv.2022.156188. [PMID: 35618132]
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  • Chunyang Du, Yan Zhu, Yan Yang, Lin Mu, Xue Yan, Ming Wu, Chenming Zhou, Haijiang Wu, Wei Zhang, Yanhui Wu, Guoyu Zhang, Yue Hu, Yunzhuo Ren, Yonghong Shi. C1q/tumour necrosis factor-related protein-3 alleviates high-glucose-induced lipid accumulation and necroinflammation in renal tubular cells by activating the adenosine monophosphate-activated protein kinase pathway. The international journal of biochemistry & cell biology. 2022 08; 149(?):106247. doi: 10.1016/j.biocel.2022.106247. [PMID: 35753650]
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  • Marko Lucijanic, Tomislav Cikara, Petra Bistrovic, Ivan Papic, Maja Ortner Hadziabdic, Nikolina Busic, Marina Lackovic, Natalia Cesar, Valentina Koscak, Josko Mitrovic, Bruno Barsic, Tomo Lucijanic. Remdesivir use in COVID-19 patients might predispose bacteremia, matched case-control analysis. The Journal of infection. 2022 Aug; 85(2):174-211. doi: 10.1016/j.jinf.2022.04.045. [PMID: 35513188]
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