Dichlorprop (BioDeep_00000002933)
Secondary id: BioDeep_00001871637
human metabolite blood metabolite
代谢物信息卡片
2-Methyl-2-(2,4-dichlorophenoxy)acetic acid
化学式: C9H8Cl2O3 (233.9850478)
中文名称: 2,4-滴丙酸
谱图信息:
最多检出来源 Mentha canadensis(plant) 6.67%
分子结构信息
SMILES: CC(C(=O)O)OC1=C(C=C(C=C1)Cl)Cl
InChI: InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)
描述信息
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8393
CONFIDENCE standard compound; EAWAG_UCHEM_ID 270
同义名列表
14 个代谢物同义名
2-Methyl-2-(2,4-dichlorophenoxy)acetic acid; 2-(2,4-Dichlorophenoxy)propionic acid; 2-(2,4-Dichlorophenoxy)propanoic acid; 2-(2,4-Dichlorophenoxy)propionate; Dichlorprop, potassium salt; Dichlorprop, (+,-)-isomer; Dichlorprop, sodium salt; Dichlorprop, (S)-isomer; Dichlorprop, (R)-isomer; (+,-)-dichlorprop; Dichloroprop; Dichlorprop; 2,4-DP CPD; 2,4-DP
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:75370
- ChEBI: CHEBI:75375
- KEGG: C11020
- PubChem: 8427
- HMDB: HMDB0251202
- Metlin: METLIN68777
- ChEMBL: CHEMBL573221
- Wikipedia: Dichlorprop
- CAS: 120-36-5
- MoNA: EA027056
- MoNA: EA027058
- MoNA: EA027052
- MoNA: EA027063
- MoNA: EA027051
- MoNA: EA027061
- MoNA: EA027064
- MoNA: EA027055
- MoNA: EA027053
- MoNA: EA027060
- MoNA: EA027062
- MoNA: EA027059
- MoNA: SM839351
- MoNA: EA027054
- MoNA: EA027057
- PMhub: MS000007233
- PubChem: 13203
- NIKKAJI: J3.254I
- RefMet: Dichlorprop
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Rui-Kun Zhang, Kun Yan, Hai-Feng Chen, Yang Zhang, Gui-Jin Li, Xiao-Gang Chen, Lin-Pu Ge, Feng Cheng, Zhi-Neng Chen, Xin-Miao Yao. Anti-osteoporotic drugs affect the pathogenesis of gut microbiota and its metabolites: a clinical study.
Frontiers in cellular and infection microbiology.
2023; 13(?):1091083. doi:
10.3389/fcimb.2023.1091083. [PMID: 37475958] - Danyan Qiu, Yizhi Ye, Mingjing Ke, Nuohan Xu, Zhenyan Zhang, Fan Zhang, Jian Kang, Yitian Yu, Tao Lu, Haifeng Qian. Effects of chiral herbicide dichlorprop on Arabidopsis thaliana metabolic profile and its implications for microbial communities in the phyllosphere.
Environmental science and pollution research international.
2022 Apr; 29(19):28256-28266. doi:
10.1007/s11356-021-17936-y. [PMID: 34988791] - Qi Zhang, Yizhi Ye, Qian Qu, Yitian Yu, Mingkang Jin, Tao Lu, Haifeng Qian. Enantioselective metabolomic modulations in Arabidopsis thaliana leaf induced by the herbicide dichlorprop.
The Science of the total environment.
2021 Nov; 797(?):149015. doi:
10.1016/j.scitotenv.2021.149015. [PMID: 34346373] - Hui Chen, Yongxiang Qin, Jiawei Pu, Jinxing Hu, Yuezhong Wen. Phytotoxicity of the chiral herbicide dichlorprop: Cross-talk between nitric oxide, reactive oxygen species and phytohormones.
The Science of the total environment.
2021 Sep; 788(?):147866. doi:
10.1016/j.scitotenv.2021.147866. [PMID: 34134377] - Jun Li, Siyu Chen, Jinye Huang, Hui Chen, Zunwei Chen, Yuezhong Wen. New Target in an Old Enemy: Herbicide (R)-Dichlorprop Induces Ferroptosis-like Death in Plants.
Journal of agricultural and food chemistry.
2021 Jul; 69(27):7554-7564. doi:
10.1021/acs.jafc.1c02102. [PMID: 34196530] - Siyu Chen, Hui Chen, Zunwei Chen, Yuezhong Wen, Weiping Liu. Enantioselective Phytotoxic Disturbances of Fatty Acids in Arabidopsis thaliana by Dichlorprop.
Environmental science & technology.
2019 Aug; 53(15):9252-9259. doi:
10.1021/acs.est.9b03744. [PMID: 31290320] - Zunwei Chen, Jia Wang, Siyu Chen, Yuezhong Wen. Enantioselective disturbance of chiral herbicide dichlorprop to nitrogen metabolism of Arabidopsis thaliana: Regular analysis and stable isotope attempt.
The Science of the total environment.
2017 Dec; 603-604(?):533-540. doi:
10.1016/j.scitotenv.2017.06.037. [PMID: 28645051] - Zunwei Chen, Jia Wang, Hui Chen, Yuezhong Wen, Weiping Liu. Enantioselective Phytotoxicity of Dichlorprop to Arabidopsis thaliana: The Effect of Cytochrome P450 Enzymes and the Role of Fe.
Environmental science & technology.
2017 Oct; 51(20):12007-12015. doi:
10.1021/acs.est.7b04252. [PMID: 28906105] - Zunwei Chen, Hui Chen, Yuqin Zou, Yuezhong Wen. Stomatal behaviors reflect enantioselective phytotoxicity of chiral herbicide dichlorprop in Arabidopsis thaliana.
The Science of the total environment.
2016 08; 562(?):73-80. doi:
10.1016/j.scitotenv.2016.03.205. [PMID: 27092421] - Xiaoxiao Feng, Jianlei Yu, Lixiang Pan, Guochun Song, Hongyan Zhang. Dissipation and Residues of Dichlorprop-P and Bentazone in Wheat-Field Ecosystem.
International journal of environmental research and public health.
2016 05; 13(6):. doi:
10.3390/ijerph13060534. [PMID: 27240385] - Pavel Kerchev, Per Mühlenbock, Jordi Denecker, Kris Morreel, Frank A Hoeberichts, Katrien Van Der Kelen, Micheal Vandorpe, Long Nguyen, Dominique Audenaert, Frank Van Breusegem. Activation of auxin signalling counteracts photorespiratory H2O2-dependent cell death.
Plant, cell & environment.
2015 02; 38(2):253-65. doi:
10.1111/pce.12250. [PMID: 26317137] - Sibel Tunç, Osman Duman, Inanç Soylu, Bahar Kancı Bozoğlan. Study on the bindings of dichlorprop and diquat dibromide herbicides to human serum albumin by spectroscopic methods.
Journal of hazardous materials.
2014 May; 273(?):36-43. doi:
10.1016/j.jhazmat.2014.03.022. [PMID: 24709480] - D Boels, C Monteil-Ganière, A Turcant, M Bretaudeau, P Harry. Triketone toxicity: a report on two cases of sulcotrione poisoning.
Human & experimental toxicology.
2013 Jul; 32(7):778-82. doi:
10.1177/0960327112468908. [PMID: 23821594] - Claire Philippat, Marion Mortamais, Cécile Chevrier, Claire Petit, Antonia M Calafat, Xiaoyun Ye, Manori J Silva, Christian Brambilla, Isabelle Pin, Marie-Aline Charles, Sylvaine Cordier, Rémy Slama. Exposure to phthalates and phenols during pregnancy and offspring size at birth.
Environmental health perspectives.
2012 Mar; 120(3):464-70. doi:
10.1289/ehp.1103634. [PMID: 21900077] - Thomas Hartwig, Claudia Corvalan, Norman B Best, Joshua S Budka, Jia-Ying Zhu, Sunghwa Choe, Burkhard Schulz. Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize.
PloS one.
2012; 7(5):e36625. doi:
10.1371/journal.pone.0036625. [PMID: 22590578] - Jerry M Green, Micheal D K Owen. Herbicide-resistant crops: utilities and limitations for herbicide-resistant weed management.
Journal of agricultural and food chemistry.
2011 Jun; 59(11):5819-29. doi:
10.1021/jf101286h. [PMID: 20586458] - Rosemary Castorina, Asa Bradman, Laura Fenster, Dana Boyd Barr, Roberto Bravo, Michelle G Vedar, Martha E Harnly, Thomas E McKone, Ellen A Eisen, Brenda Eskenazi. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES.
Environmental health perspectives.
2010 Jun; 118(6):856-63. doi:
10.1289/ehp.0901568. [PMID: 20129873] - Emeline L Maillet, Robert F Margolskee, Bedrich Mosinger. Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Journal of medicinal chemistry.
2009 Nov; 52(21):6931-5. doi:
10.1021/jm900823s. [PMID: 19817384] - Grazia Laura Gambino, Pietro Pagano, Monica Scordino, Leonardo Sabatino, Emanuele Scollo, Pasqualino Traulo, Giacomo Gagliano. Determination of plant hormones in fertilizers by high-performance liquid chromatography with photodiode array detection: method development and single-laboratory validation.
Journal of AOAC International.
2008 Nov; 91(6):1245-56. doi:
. [PMID: 19202783] - N Rosales-Conrado, M E León-González, L V Pérez-Arribas, L M Polo-Díez. Multiresidue determination of chlorophenoxy acid herbicides in human urine samples by use of solid-phase extraction and capillary LC-UV detection.
Analytical and bioanalytical chemistry.
2008 Jan; 390(2):759-68. doi:
10.1007/s00216-007-1701-5. [PMID: 17987282] - Markus Gershater, Kate Sharples, Robert Edwards. Carboxylesterase activities toward pesticide esters in crops and weeds.
Phytochemistry.
2006 Dec; 67(23):2561-7. doi:
10.1016/j.phytochem.2006.09.019. [PMID: 17078983] - Ignaz J Buerge, Thomas Poiger, Markus D Müller, Hans-Rudolf Buser. Influence of pH on the stereoselective degradation of the fungicides epoxiconazole and cyproconazole in soils.
Environmental science & technology.
2006 Sep; 40(17):5443-50. doi:
10.1021/es060817d. [PMID: 16999123] - Ignaz I Buerge, Thomas Poiger, Markus D Müller, Hans-Rudolf Buser. Enantioselective degradation of metalaxyl in soils: chiral preference changes with soil pH.
Environmental science & technology.
2003 Jun; 37(12):2668-74. doi:
10.1021/es0202412. [PMID: 12854703] - G Rijckaert, D Lepiece. Study of the selectivity of PRIMSTAR (fluroxypyr + florasulam) in two key grass species (FESRU & LOLPE) grown for seed production.
Communications in agricultural and applied biological sciences.
2003; 68(4 Pt A):381-90. doi:
. [PMID: 15149133] - C W Thorstensen, O Lode, O M Eklo, A Christiansen. Sorption of bentazone, dichlorprop, MCPA, and propiconazole in reference soils from Norway.
Journal of environmental quality.
2001 Nov; 30(6):2046-52. doi:
10.2134/jeq2001.2046. [PMID: 11790012] - C W Thorstensen, A Christiansen. Determination of bentazone, dichlorprop, and MCPA in different soils by sodium hydroxide extraction in combination with solid-phase preconcentration.
Journal of agricultural and food chemistry.
2001 Sep; 49(9):4199-202. doi:
10.1021/jf0014415. [PMID: 11559110] - C W Thorstensen, O Lode. Laboratory degradation studies of bentazone, dichlorprop, MCPA, and propiconazole in Norwegian soils.
Journal of environmental quality.
2001 May; 30(3):947-53. doi:
10.2134/jeq2001.303947x. [PMID: 11401285] - S Y Chiou, W W Su, Y C Su. Optimizing production of polyunsaturated fatty acids in Marchantia polymorpha cell suspension culture.
Journal of biotechnology.
2001 Feb; 85(3):247-57. doi:
10.1016/s0168-1656(00)00346-1. [PMID: 11173092] - J M Schneiderheinze, D W Armstrong, A Berthod. Plant and soil enantioselective biodegradation of racemic phenoxyalkanoic herbicides.
Chirality.
1999; 11(4):330-7. doi:
10.1002/(sici)1520-636x(1999)11:4<330::aid-chir12>3.0.co;2-g. [PMID: 10224660] - C Zipper, C Bolliger, T Fleischmann, M J Suter, W Angst, M D Müller, H P Kohler. Fate of the herbicides mecoprop, dichlorprop, and 2,4-D in aerobic and anaerobic sewage sludge as determined by laboratory batch studies and enantiomer-specific analysis.
Biodegradation.
1999; 10(4):271-8. doi:
10.1023/a:1008396022622. [PMID: 10633543] - A West, M Frost, H Köhler. Comparison of HPLC and CE for the analysis of dichlorprop in a case of intoxication.
International journal of legal medicine.
1997; 110(5):251-3. doi:
10.1007/s004140050080. [PMID: 9297580] - Y Koibuchi, J Yamada, T Watanabe, T Suga. Lack of stereoselectivity in rat liver peroxisomal enzyme induction by optically active phenoxyacetic acids.
Biological & pharmaceutical bulletin.
1993 Jan; 16(1):39-42. doi:
10.1248/bpb.16.39. [PMID: 8369750] - C Schröder, E Krüger, J Abel. [Acute poisoning caused by the herbicide dichlorprop (preparation SYS 67 PROP)].
Kinderarztliche Praxis.
1991 Mar; 59(3):81-4. doi:
. [PMID: 2056670] - H Beitz, U Banasiak, S Gericke, P Clausing. Toxicokinetics of the herbicide dichlorprop and its leucinate and their action on liver mixed function oxidase in rats.
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.
1985; 8(?):259-63. doi:
10.1007/978-3-642-69928-3_38. [PMID: 3868352] - S Gericke, P Clausing, R Binner, D Gründel, H Beitz. [Kinetics of the herbicide dichlorprop and its leucine conjugate in rat serum and bile].
Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete.
1984 Nov; 30(11):615-7. doi:
NULL. [PMID: 6523931] - T Kh Vergeĭchik, E N Vergeĭchik, V A Linnikova, E A Griaznova. [Use of the orthogonal function method for background suppression in forensic chemical determination of various herbicides in biological material].
Sudebno-meditsinskaia ekspertiza.
1984 Jul; 27(3):47-9. doi:
NULL. [PMID: 6485039] - S Libich, J C To, R Frank, G J Sirons. Occupational exposure of herbicide applicators to herbicides used along electric power transmission line right-of-way.
American Industrial Hygiene Association journal.
1984 Jan; 45(1):56-62. doi:
10.1080/15298668491399370. [PMID: 6702600] - B Kolmodin-Hedman, S Höglund, M Akerblom. Studies on phenoxy acid herbicides. I. Field study. Occupational exposure to phenoxy acid herbicides (MCPA, dichlorprop, mecoprop and 2,4-D) in agriculture.
Archives of toxicology.
1983 Dec; 54(4):257-65. doi:
10.1007/bf01234478. [PMID: 6667116] - G Wambach, J R Higgins. Effect of progesterone on serum and tissue electrolyte concentration in doca-treated rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1979 Mar; 11(3):258-9. doi:
10.1055/s-0028-1095777. [PMID: 447212]