Phoxim (BioDeep_00000002801)
代谢物信息卡片
alpha-(((Diethoxyphosphinothioyl)oxy)imino)benzeneacetonitrile
化学式: C12H15N2O3PS (298.054097)
中文名称: 甲醇中辛硫磷溶液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOP(=S)(OCC)ON=C(C#N)C1=CC=CC=C1
InChI: InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-14-12(10-13)11-8-6-5-7-9-11/h5-9H,3-4H2,1-2H3/b14-12+
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:38812
- KEGG: C18757
- KEGGdrug: D08373
- PubChem: 5360460
- PubChem: 9570290
- Metlin: METLIN72530
- ChEMBL: CHEMBL1906626
- CAS: 217075-81-5
- CAS: 14816-18-3
- CAS: 217075-82-6
- PMhub: MS000005252
- PubChem: 124489431
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Tianmeng Guo, Chongyang Li, Yiming Zhao, Xixi Huang, Ziyi Luo, Haolong Li, Airong Liu, Golam Jalal Ahammed, Shuangchen Chen. Cytochrome P450 CYP736A12 is crucial for Trichoderma asperellum-induced alleviation of phoxim phytotoxicity and reduction of pesticide residue in tomato roots.
Journal of hazardous materials.
2024 Jun; 471(?):134299. doi:
10.1016/j.jhazmat.2024.134299. [PMID: 38631252] - Fu Cao, Jia-Min Yu, Hui-Mei Sun, Ji-Xian He, Shi-Guang Li, Su Liu, Mao-Ye Li. Epsilon Class Glutathione S-Transferase Confers Phoxim Tolerance in the Black Cutworm Agrotis ipsilon (Lepidoptera: Noctuidae).
Journal of agricultural and food chemistry.
2023 Dec; 71(51):20680-20689. doi:
10.1021/acs.jafc.3c07964. [PMID: 38088263] - Shaimaa H Mohammed, Mohamed M Baz, Moustafa Ibrahim, Ibrahim T Radwan, Abdelfattah Selim, Abdel-Fattah D Dawood, Hanan A A Taie, Salwa Abdalla, Hanem F Khater. Acaricide resistance and novel photosensitizing approach as alternative acaricides against the camel tick, Hyalomma dromedarii.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
2023 Jan; 22(1):87-101. doi:
10.1007/s43630-022-00301-4. [PMID: 36127561] - J N Wang, C Wang, J Wang, Y X Song, Y P He, Z X Lu. [One case of rhabdomyolysis caused by acute phoxim poisoning].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2022 Oct; 40(10):782-784. doi:
10.3760/cma.j.cn121094-20211027-00520. [PMID: 36348563] - Jin Tae Kim, Hong Jin Lee, Hee-Seok Lee. Organophosphorus pesticides exert estrogen receptor agonistic effect determined using Organization for Economic Cooperation and Development PBTG455, and induce estrogen receptor-dependent adipogenesis of 3T3-L1 adipocytes.
Environmental pollution (Barking, Essex : 1987).
2021 Aug; 283(?):117090. doi:
10.1016/j.envpol.2021.117090. [PMID: 33872936] - Yan-Hong Shi, Jin-Jing Xiao, Yu-Ying Liu, Ya-Jing Deng, Wen-Zhe Feng, Dong Wei, Min Liao, Hai-Qun Cao. Gut microbiota influence on oral bioaccessibility and intestinal transport of pesticides in Chaenomeles speciosa.
Food chemistry.
2021 Mar; 339(?):127985. doi:
10.1016/j.foodchem.2020.127985. [PMID: 32920305] - Sheng Sheng, Jiao Wang, Xiao-Rui Zhang, Zhi-Xiang Liu, Meng-Wen Yan, Ying Shao, Jin-Cheng Zhou, Fu-An Wu, Jun Wang. Evaluation of Sensitivity to Phoxim and Cypermethrin in an Endoparasitoid, Meteorus pulchricornis (Wesmael) (Hymenoptera: Braconidae), and Its Parasitization Efficiency Under Insecticide Stress.
Journal of insect science (Online).
2021 Jan; 21(1):. doi:
10.1093/jisesa/ieab002. [PMID: 33580255] - Shuangchen Chen, Yaru Yan, Yaqi Wang, Meijuan Wu, Qi Mao, Yifei Chen, Jingjing Ren, Airong Liu, Xiaomin Lin, Golam Jalal Ahammed. Trichoderma asperellum reduces phoxim residue in roots by promoting plant detoxification potential in Solanum lycopersicum L.
Environmental pollution (Barking, Essex : 1987).
2020 Apr; 259(?):113893. doi:
10.1016/j.envpol.2019.113893. [PMID: 31918147] - Jingjie An, Chang Liu, Ya'nan Dou, Zhanlin Gao, Zhihong Dang, Xiu Yan, Wenliang Pan, Yaofa Li. Analysis of Differentially Expressed Transcripts in Apolygus lucorum (Meyer-Dür) Exposed to Different Temperature Coefficient Insecticides.
International journal of molecular sciences.
2020 Jan; 21(2):. doi:
10.3390/ijms21020658. [PMID: 31963875] - Di Meng, Liyuan Zhang, Jie Meng, Qiaopeng Tian, Lixin Zhai, Zhikui Hao, Zhengbing Guan, Yujie Cai, Xiangru Liao. Evaluation of the Strain Bacillus amyloliquefaciens YP6 in Phoxim Degradation via Transcriptomic Data and Product Analysis.
Molecules (Basel, Switzerland).
2019 Nov; 24(21):. doi:
10.3390/molecules24213997. [PMID: 31694203] - Yongping Zheng, Songjie Wu, Jie Dang, Shifang Wang, Zhengxin Liu, Jing Fang, Ping Han, Jue Zhang. Reduction of phoxim pesticide residues from grapes by atmospheric pressure non-thermal air plasma activated water.
Journal of hazardous materials.
2019 09; 377(?):98-105. doi:
10.1016/j.jhazmat.2019.05.058. [PMID: 31153118] - Hong-Yi Ji, Christian Staehelin, Yan-Ping Jiang, Shi-Wei Liu, Zhi-Hui Ma, Yi-Juan Su, Jia-En Zhang, Rui-Long Wang. Tobacco Cutworm (Spodoptera Litura) Larvae Silenced in the NADPH-Cytochrome P450 Reductase Gene Show Increased Susceptibility to Phoxim.
International journal of molecular sciences.
2019 Aug; 20(15):. doi:
10.3390/ijms20153839. [PMID: 31390813] - Xinxian Qin, Xiaoshuang Luo, Ye Chen, Jiahua Han, Ji Zhang, Kankan Zhang, Deyu Hu. A liquid chromatography-tandem mass spectrometry method to simultaneously determinate dichlorvos and phoxim in tobacco.
Biomedical chromatography : BMC.
2019 Jul; 33(7):e4537. doi:
10.1002/bmc.4537. [PMID: 30897223] - Jing Zhang, Wentao Song, Yuecheng Sun, Anshan Shan. Effects of phoxim-induced hepatotoxicity on SD rats and the protection of vitamin E.
Environmental science and pollution research international.
2017 Nov; 24(32):24916-24927. doi:
10.1007/s11356-017-0104-1. [PMID: 28918601] - Yunhe Zhao, Qiuhong Wang, Yao Wang, Zhengqun Zhang, Yan Wei, Feng Liu, Chenggang Zhou, Wei Mu. Chlorfenapyr, a Potent Alternative Insecticide of Phoxim To Control Bradysia odoriphaga (Diptera: Sciaridae).
Journal of agricultural and food chemistry.
2017 Jul; 65(29):5908-5915. doi:
10.1021/acs.jafc.7b02098. [PMID: 28672113] - Da-xia Zhang, Bei-xing Li, Xian-peng Zhang, Zheng-qun Zhang, Wei-chang Wang, Feng Liu. Phoxim Microcapsules Prepared with Polyurea and Urea-Formaldehyde Resins Differ in Photostability and Insecticidal Activity.
Journal of agricultural and food chemistry.
2016 Apr; 64(14):2841-6. doi:
10.1021/acs.jafc.6b00231. [PMID: 27010712] - Bo Zhao, Lanju Yang, Lei Xiao, Baoquan Sun, Xianbao Zou, Dongmei Gao, Xiandong Jian. [The influence of sodium bicarbonate combined with ulinastatin on cholinesterase activity for patients with acute phoxim pesticide poisoning].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2016 Jan; 34(1):53-5. doi:
10.3760/cma.j.issn.1001-9391.2016.01.015. [PMID: 27014821] - Li-min Zhao, Qi-ming Wang, Dong-dong Zhang, Gui-lan Ma. [Cooperative Protection of American Ginseng Seedlings by Applying Imidacloprid, Fludioxonil and Phoxim].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2015 Jul; 38(7):1349-54. doi:
. [PMID: 26946830] - Junju Su, Bing Li, Shen Cheng, Zhou Zhu, Xuezi Sang, Suxin Gui, Yi Xie, Qingqing Sun, Zhe Cheng, Jie Cheng, Rengping Hu, Weide Shen, Qingyou Xia, Ping Zhao, Fashui Hong. Phoxim-induced damages of Bombyx mori larval midgut and titanium dioxide nanoparticles protective role under phoxim-induced toxicity.
Environmental toxicology.
2014 Dec; 29(12):1355-66. doi:
10.1002/tox.21866. [PMID: 23595993] - Lanjie Xu, Xiaoliang Duan, Yanhua Lv, Xiaohua Zhang, Zhansheng Nie, Chaojie Xie, Zhongfu Ni, Rongqi Liang. Silencing of an aphid carboxylesterase gene by use of plant-mediated RNAi impairs Sitobion avenae tolerance of Phoxim insecticides.
Transgenic research.
2014 Apr; 23(2):389-96. doi:
10.1007/s11248-013-9765-9. [PMID: 24242160] - Yihua Yang, Yapeng Li, Yidong Wu. Current status of insecticide resistance in Helicoverpa armigera after 15 years of Bt cotton planting in China.
Journal of economic entomology.
2013 Feb; 106(1):375-81. doi:
10.1603/ec12286. [PMID: 23448054] - Sheng-Yin Wang, Yi Yu, Yong-Jie Liu, Jing-Yu Ma. [Resistance risk and resistance stability of Frankliniella occidentalis to imidacloprid, emamectin benzoate, and phoxim].
Ying yong sheng tai xue bao = The journal of applied ecology.
2012 Dec; 23(12):3429-34. doi:
. [PMID: 23479887] - Sheng-Yin Wang, Xian-Hong Zhou, An-Sheng Zhang, Li-Li Li, Xing-Yuan Men, Si-Cong Zhang, Yong-Jie Liu, Yi Yu. [Resistance mechanisms and cross-resistance of phoxim-resistant Frankliniella occidentalis Pergande population].
Ying yong sheng tai xue bao = The journal of applied ecology.
2012 Jul; 23(7):1933-9. doi:
. [PMID: 23173470] - Fa Yuan Wang, Rui Jian Tong, Zhao Yong Shi, Xiao Feng Xu, Xin Hua He. Inoculations with arbuscular mycorrhizal fungi increase vegetable yields and decrease phoxim concentrations in carrot and green onion and their soils.
PloS one.
2011 Feb; 6(2):e16949. doi:
10.1371/journal.pone.0016949. [PMID: 21347374] - Fa Yuan Wang, Zhao Yong Shi, Rui Jian Tong, Xiao Feng Xu. Dynamics of phoxim residues in green onion and soil as influenced by arbuscular mycorrhizal fungi.
Journal of hazardous materials.
2011 Jan; 185(1):112-6. doi:
10.1016/j.jhazmat.2010.09.004. [PMID: 20870354] - Fa-Yuan Wang, Xin Chen, Xian-Ming Sun, Zhao-Yong Shi. [Influence of arbuscular mycorrhizal inoculation on growth and phoxim residue of carrot (Daucus carota L.)].
Huan jing ke xue= Huanjing kexue.
2010 Dec; 31(12):3075-80. doi:
. [PMID: 21360902] - Jing-Yi Hu, Xin-Ru Wang. [Joint action of phoxim and fenvalerate on spermatogenesis of male rats].
Zhonghua nan ke xue = National journal of andrology.
2008 Nov; 14(11):968-72. doi:
. [PMID: 19102494] - Yue-Liang Zhang, Wei Mu, Zhao-Liang Chen, Zhi-Ren Han, Chao Ma, Ru-Huan Zhai. [Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering].
Ying yong sheng tai xue bao = The journal of applied ecology.
2007 Aug; 18(8):1913-6. doi:
. [PMID: 17974266] - Sandra Gómez-Arroyo, Josefina Cortés-Eslava, Rafael Villalobos-Pietrini, María Elena Calderón-Segura, Ana Rosa Flores-Márquez, Jesús Javier Espinosa-Aguirre. Differential mutagenic response of Salmonella typhimurium to the plant-metabolized organophosphorus insecticides, phoxim and azinphos methyl.
Toxicology in vitro : an international journal published in association with BIBRA.
2007 Aug; 21(5):950-5. doi:
10.1016/j.tiv.2007.01.027. [PMID: 17383850] - Sasithorn Limsuwan, Beate Priess, Natthasit Tansakul, Heinz Nau, Manfred Kietzmann, Gerd Hamscher. Penetration studies of propoxur and phoxim from eggshell into whole egg after experimental exposure and application in henhouses.
Journal of agricultural and food chemistry.
2007 Jul; 55(15):6401-5. doi:
10.1021/jf070987p. [PMID: 17602660] - Li-Chun Xu, Hong Sun, Jian-Feng Chen, Qian Bian, Ling Song, Xin-Ru Wang. Androgen receptor activities of p,p'-DDE, fenvalerate and phoxim detected by androgen receptor reporter gene assay.
Toxicology letters.
2006 Jan; 160(2):151-7. doi:
10.1016/j.toxlet.2005.06.016. [PMID: 16125883] - Kongming Wu, Wei Mu, Gemei Liang, Yuyuan Guo. Regional reversion of insecticide resistance in Helicoverpa armigera (Lepidoptera: Noctuidae) is associated with the use of Bt cotton in northern China.
Pest management science.
2005 May; 61(5):491-8. doi:
10.1002/ps.999. [PMID: 15643649] - Li-Chun Xu, Ning-Yu Zhan, Ru Liu, Ling Song, Xin-Ru Wang. Joint action of phoxim and fenvalerate on reproduction in male rats.
Asian journal of andrology.
2004 Dec; 6(4):337-41. doi:
. [PMID: 15546026] - Jun Chen, Tong-Ning Liu, Xing-Hua Zhu, Hui-Zhen Chen. [Occurrence and control of pests about Cistanche deserticola and its hosts].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2004 Aug; 29(8):730-3. doi:
". [PMID: 15506278] - Kongming Wu, Yuyuan Guo. Changes in susceptibility to conventional insecticides of a Cry1Ac-selected population of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae).
Pest management science.
2004 Jul; 60(7):680-4. doi:
10.1002/ps.848. [PMID: 15260299] - M Heinonen, S Bornstein, R Kolhinen, H Saloniemi, V Tuovinen. Eradication of porcine sarcoptic mange within a health declared production model.
Acta veterinaria Scandinavica.
2000; 41(1):41-50. doi:
. [PMID: 10920475] - M Jacobson, S Bornstein, P Wallgren. The efficacy of simplified eradication strategies against sarcoptic mange mite infections in swine herds monitored by an ELISA.
Veterinary parasitology.
1999 Mar; 81(3):249-58. doi:
10.1016/s0304-4017(98)00247-7. [PMID: 10190868] - M Atef, S A Youssef, A Ramadan, M F Nawito, M K el-Sayed, H Abd el-Rahman. Influence of Phoxim on testicular and seminal vesicle organs, testosterone and cholinesterase level and its tissue residues in male rats.
DTW. Deutsche tierarztliche Wochenschrift.
1995 Aug; 102(8):01-5. doi:
. [PMID: 8591759] - S Suzuki, Y Ogawa, E Kamata, K Naito, T Umemura, M Saito, T Kaneko, Y Kurokawa. [A 28-day repeated dose toxicity test of Phoxim in Wistar rats].
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences.
1994; ?(112):40-7. doi:
. [PMID: 8854901] - A M Orlova. [Isolation and quantitative determination of phoxim in biological material].
Sudebno-meditsinskaia ekspertiza.
1986 Oct; 29(4):48-52. doi:
NULL. [PMID: 3798513] - T A Morsy, M S Sadek, M Y Abdel Hamid. Intestinal parasites of stray cats in Cairo, Egypt.
Journal of the Egyptian Society of Parasitology.
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Ukrainskii biokhimicheskii zhurnal (1978).
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