Daphnetol (BioDeep_00000000272)
Secondary id: BioDeep_00000400386, BioDeep_00000863712
natural product human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C9H6O4 (178.0266)
中文名称: 瑞香素
谱图信息:
最多检出来源 Viridiplantae(plant) 18.39%
Last reviewed on 2024-09-04.
Cite this Page
Daphnetol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/daphnetol (retrieved
2024-12-30) (BioDeep RN: BioDeep_00000000272). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C1=CC(=C(C2=C1C=CC(=O)O2)O)O
InChI: InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
描述信息
7,8-dihydroxycoumarin is a hydroxycoumarin.
Daphnetin is a natural product found in Euphorbia dracunculoides, Rhododendron lepidotum, and other organisms with data available.
Acquisition and generation of the data is financially supported in part by CREST/JST.
Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1?, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research[1][2][3][4].
Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1?, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research[1][2][3][4].
Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1?, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research[1][2][3][4].
Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1?, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research
Daphnetin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=486-35-1 (retrieved 2024-09-04) (CAS RN: 486-35-1). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
同义名列表
31 个代谢物同义名
InChI=1/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12; 5-18-03-00211 (Beilstein Handbook Reference); 2H-1-Benzopyran-2-one, 7,8-dihydroxy-; 7,8-Dihydroxycoumarin, >=97\\%, powder; 7,8-dihydroxy-2H-1-benzopyran-2-one; 7,8-DIHYDROXY-2H-BENZOPYRAN-2-ONE; 7,8-Dihydroxy-2H-chromen-2-one #; 7,8-Dihydroxy-2H-chromen-2-one; 7,8-Dihydroxycoumarin, 90\\%; ATEFPOUAMCWAQS-UHFFFAOYSA-N; 7,8-DIHYDROXY-CHROMEN-2-ONE; 7,8-dihydroxychromen-2-one; COUMARIN, 7,8-DIHYDROXY-; 7,8-dihydroxy-coumarin; 1,8-Dihydroxycoumarin; 7,8-Dihydroxycoumarin; Spectrum3_000784; DAPHNETIN [INCI]; Spectrum4_001254; DAPHNETIN [MI]; Oprea1_044324; DivK1c_006960; Lopac0_000330; KBio1_001904; HSCI1_000053; Tox21_500330; KBio3_001708; Daphnetol; Daphnetin; 7,8-Dihydroxycoumarin; Daphnetin
数据库引用编号
27 个数据库交叉引用编号
- ChEBI: CHEBI:17313
- KEGG: C03093
- PubChem: 5280569
- HMDB: HMDB0130547
- Metlin: METLIN65905
- ChEMBL: CHEMBL244948
- MeSH: daphnetin
- ChemIDplus: 0000486351
- MetaCyc: CPD-14427
- chemspider: 4444191
- CAS: 486-35-1
- MoNA: PR100936
- MoNA: PS124901
- MoNA: PS124909
- MoNA: PR100937
- MoNA: PS124903
- MoNA: PR100473
- MoNA: PS124902
- MoNA: PS124907
- MoNA: PS124908
- medchemexpress: HY-N0281
- PMhub: MS000010027
- KNApSAcK: C00002462
- 3DMET: B00541
- NIKKAJI: J6.008I
- PubChem: 5991
- KNApSAcK: 17313
分类词条
相关代谢途径
Reactome(0)
代谢反应
84 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(2)
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnin interconversion:
H2O + daphnin ⟶ D-glucopyranose + daphnetin
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(82)
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnin interconversion:
H2O + daphnin ⟶ D-glucopyranose + daphnetin
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnin interconversion:
H2O + daphnin ⟶ D-glucopyranose + daphnetin
- daphnetin modification:
UDP-α-D-glucose + daphnetin ⟶ 3-O-β-D-glucosyl-daphnetin + H+ + UDP
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
D-glucopyranose + daphnetin ⟶ H2O + daphnetin-8-glucoside
- daphnetin modification:
SAM + daphnetin ⟶ 7-hydroxy-8-methoxycoumarin + H+ + SAH
- daphnetin modification:
SAM + daphnetin ⟶ 7-hydroxy-8-methoxycoumarin + H+ + SAH
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
25 个相关的物种来源信息
- 262982 - Artemisia apiacea: 10.1248/CPB.28.347
- 496566 - Artemisia carvifolia: 10.1248/CPB.28.347
- 1090619 - Ayapana triplinervis: 10.1016/0031-9422(71)85045-8
- 36622 - Chaenomeles Sinensis (Thouin) Koehne: -
- 29785 - Cruciata glabra: 10.1515/ZNC-1996-9-1005
- 2753872 - Daphne acutiloba: 10.1016/S0031-9422(98)00181-2
- 546994 - Daphne bholua: 10.1016/S0367-326X(99)00010-6
- 2753873 - Daphne feddei:
- 224034 - Daphne gnidium:
- 66680 - Daphne mezereum:
- 329675 - Daphne odora:
- 224035 - Daphne oleoides: 10.1016/S0031-9422(99)00305-2
- 2715869 - Daphne papyracea: 10.1248/CPB.34.595
- 885948 - Daphne tangutica:
- 1008446 - Euphorbia dracunculoides: 10.4268/CJCMM20142015
- 526193 - Euphorbia ebracteolata Hayata: -
- 212925 - Euphorbia lathyris L.: -
- 9606 - Homo sapiens: -
- 33090 - Plants: -
- 1044962 - Rhododendron lepidotum: 10.1016/J.CCLET.2009.11.015
- 217505 - Sinacalia tangutica:
- 142738 - Stellera chamaejasme:
- 169606 - Tagetes lucida: 10.1021/JF053071W
- 138038 - Vachellia pennatula: 10.1007/S10600-005-0133-8
- 33090 - 长白瑞香: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Tianye Yang, Qian Pan, Rujing Yue, Guanghui Liu, Yuanyuan Zhou. Daphnetin alleviates silica-induced pulmonary inflammation and fibrosis by regulating the PI3K/AKT1 signaling pathway in mice.
International immunopharmacology.
2024 May; 133(?):112004. doi:
10.1016/j.intimp.2024.112004
. [PMID: 38613881] - Tianrui Zhang, Wulin Liang, Wenjing Ou, Mingqian Zhang, Shuang Cui, Shuofeng Zhang. Daphnetin alleviates neuropathic pain in chronic constrictive injury rats via regulating the NF-κB dependent CXCL1/CXCR2 signaling pathway.
Pharmaceutical biology.
2023 Dec; 61(1):746-754. doi:
10.1080/13880209.2023.2198560
. [PMID: 37177984] - Yao Wang, Liang Yang, Xiao Zhou, Ye Wang, Yijia Liang, Binshao Luo, Yuhao Dai, Zhouling Wei, Shili Li, Rong He, Wei Ding. Molecular mechanism of plant elicitor daphnetin-carboxymethyl chitosan nanoparticles against Ralstonia solanacearum by activating plant system resistance.
International journal of biological macromolecules.
2023 Jun; 241(?):124580. doi:
10.1016/j.ijbiomac.2023.124580
. [PMID: 37100321] - Yujie Guo, Huiqing Zhang, Zhe Lv, Yuna Du, Dan Li, Hui Fang, Jing You, Lijun Yu, Rong Li. Up-regulated CD38 by daphnetin alleviates lipopolysaccharide-induced lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway.
Cell communication and signaling : CCS.
2023 Mar; 21(1):66. doi:
10.1186/s12964-023-01041-3
. [PMID: 36998049] - Bo Tian, Xin Ma, Rui Jiang. Daphnetin Mitigates Ovalbumin-Induced Allergic Rhinitis in Mice by Regulating Nrf2/HO-1 and TLR4/NF-kB Signaling.
American journal of rhinology & allergy.
2023 Jan; 37(1):19-25. doi:
10.1177/19458924221124363
. [PMID: 36128844] - Yi Zhang, Lu Qu, Yun Sun, YuPing Lin, Jing Zeng, LiXia He, Xiucun Li, Wen Gu, Jian Nie, Xiaoling Yu, XiaoYun Tong, Feng Huang. Daphnetin contributes to allergen-induced Th2 cytokine expression and type 2-immune responses in atopic dermatitis and asthma.
Food & function.
2022 Nov; 13(23):12383-12399. doi:
10.1039/d2fo02518c
. [PMID: 36373505] - Li Yan, Yufan Jin, Junping Pan, Xiang He, Shiqian Zhong, Rongcai Zhang, LokLam Choi, Weiwei Su, Jiaxu Chen. 7,8-Dihydroxycoumarin Alleviates Synaptic Loss by Activated PI3K-Akt-CREB-BDNF Signaling in Alzheimer's Disease Model Mice.
Journal of agricultural and food chemistry.
2022 Jun; 70(23):7130-7138. doi:
10.1021/acs.jafc.2c02140
. [PMID: 35657168] - Abu Mohammad Syed, Sourav Kundu, Chetan Ram, Uttam Kulhari, Akhilesh Kumar, Madhav Nilakanth Mugale, Purusottam Mohapatra, Upadhyayula Suryanarayana Murty, Bidya Dhar Sahu. Up-regulation of Nrf2/HO-1 and inhibition of TGF-β1/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice.
Free radical biology & medicine.
2022 06; 186(?):17-30. doi:
10.1016/j.freeradbiomed.2022.04.019
. [PMID: 35513128] - Peipei Gao, Zhen Wang, Mengyao Lei, Jiaxing Che, Shuangxi Zhang, Tiantian Zhang, Yachong Hu, Le Shi, Li Cui, Jiankang Liu, Mami Noda, Yunhua Peng, Jiangang Long. Daphnetin ameliorates Aβ pathogenesis via STAT3/GFAP signaling in an APP/PS1 double-transgenic mouse model of Alzheimer's disease.
Pharmacological research.
2022 06; 180(?):106227. doi:
10.1016/j.phrs.2022.106227
. [PMID: 35452800] - Tianye Yang, Xiaoli Wang, Liang Guo, Fang Zheng, Chun Meng, Yongzheng Zheng, Guanghui Liu. Daphnetin inhibits corneal inflammation and neovascularization on a mouse model of corneal alkali burn.
International immunopharmacology.
2022 Feb; 103(?):108434. doi:
10.1016/j.intimp.2021.108434
. [PMID: 34920334] - Liang Yang, Zhouling Wei, Shili Li, Rui Xiao, Qinqin Xu, Yuao Ran, Wei Ding. Plant secondary metabolite, daphnetin reduces extracellular polysaccharides production and virulence factors of Ralstonia solanacearum.
Pesticide biochemistry and physiology.
2021 Nov; 179(?):104948. doi:
10.1016/j.pestbp.2021.104948
. [PMID: 34802533] - Houssem Boulebd, Imene Amine Khodja. A detailed DFT-based study of the free radical scavenging activity and mechanism of daphnetin in physiological environments.
Phytochemistry.
2021 Sep; 189(?):112831. doi:
10.1016/j.phytochem.2021.112831
. [PMID: 34146991] - Xiaoye Fan, Wenjing Gu, Yun Gao, Ning Ma, Changqing Fan, Xinxin Ci. Daphnetin ameliorated GM-induced renal injury through the suppression of oxidative stress and apoptosis in mice.
International immunopharmacology.
2021 Jul; 96(?):107601. doi:
10.1016/j.intimp.2021.107601
. [PMID: 33812255] - Shujun Yang, Yaodong Song, Qiaofang Wang, Yanna Liu, Zhongwei Wu, Xiaojia Duan, Yan Zhang, Xiuqian Bi, Yuanzhang Geng, Sanyang Chen, Changju Zhu. Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2-STAT3 pathway.
Scientific reports.
2021 06; 11(1):11491. doi:
10.1038/s41598-021-91008-6
. [PMID: 34075160] - Bo-Cui Song, Meng-Meng Jiang, Shuang Zhang, Hui Ma, Min Liu, Zhong-Ren Fu, Rui Wu, Chun-Yu Tong. Immunosuppressive activity of daphnetin on the humoral immune responses in ovalbumin-sensitized BALB/c mice.
Immunopharmacology and immunotoxicology.
2021 Apr; 43(2):171-175. doi:
10.1080/08923973.2021.1872618
. [PMID: 33491523] - Wenru Liu, Jun Mei, Jing Xie. Effect of locust bean gum-sodium alginate coatings incorporated with daphnetin emulsions on the quality of Scophthalmus maximus at refrigerated condition.
International journal of biological macromolecules.
2021 Feb; 170(?):129-139. doi:
10.1016/j.ijbiomac.2020.12.089
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