Cellobiose (BioDeep_00000002642)
Main id: BioDeep_00000014974
Secondary id: BioDeep_00000014320, BioDeep_00000400115
natural product human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
4-O-(a-D-Galactopyranosyl)-D-glucopyranose
化学式: C12H22O11 (342.11620619999997)
中文名称: 4-O-ALPHA-D-吡喃半乳糖基-D-葡萄糖, 4-O-(α-D-半乳糖吡喃糖基)-D-半乳糖, D(+)-纤维二糖, 可溶性淀粉, 麦芽糖浆, D-纤维二糖
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)O)CO)O)O)O)O
InChI: InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2
描述信息
D-(+)-Cellobiose is an endogenous metabolite.
D-(+)-Cellobiose is an endogenous metabolite.
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria.
同义名列表
数据库引用编号
30 个数据库交叉引用编号
- ChEBI: CHEBI:17057
- KEGG: C00185
- PubChem: 439178
- PubChem: 294
- HMDB: HMDB0000055
- Metlin: METLIN3480
- DrugBank: DB02061
- MeSH: Cellobiose
- MetaCyc: MALTOSE
- KNApSAcK: C00001136
- CAS: 80446-85-1
- CAS: 16462-44-5
- CAS: 27452-49-9
- CAS: 56907-30-3
- CAS: 29276-55-9
- CAS: 13360-52-6
- CAS: 9004-34-6
- CAS: 9005-84-9
- CAS: 528-50-7
- CAS: 69-79-4
- MoNA: PS053501
- PMhub: MS000004183
- PubChem: 3485
- PDB-CCD: CBI
- PDB-CCD: CBK
- 3DMET: B04644
- NIKKAJI: J6.676A
- RefMet: Cellobiose
- medchemexpress: HY-N2325
- medchemexpress: HY-N2024
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
13 个相关的物种来源信息
- 3702 Arabidopsis thaliana:
- 654 Aeromonas veronii: 10.3389/FCIMB.2020.00044
- 681275 Litoria verreauxii: 10.1038/SDATA.2018.33
- 49666 Paris polyphylla: 10.1016/J.JPROT.2019.02.003
- 83858 Paris fargesii: 10.1016/J.JPROT.2019.02.003
- 3702 Arabidopsis thaliana:
- 654 Aeromonas veronii: 10.3389/FCIMB.2020.00044
- 681275 Litoria verreauxii: 10.1038/SDATA.2018.33
- 49666 Paris polyphylla: 10.1016/J.JPROT.2019.02.003
- 83858 Paris fargesii: 10.1016/J.JPROT.2019.02.003
- 9606 Homo sapiens: -
- 3498 Morus alba L.: -
- 33090 Plants: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yazhe Liang, Wangli Ji, Xianhua Sun, Zhenzhen Hao, Xiaolu Wang, Yuan Wang, Wei Zhang, Yingguo Bai, Xing Qin, Huiying Luo, Bin Yao, Xiaoyun Su, Huoqing Huang. Production of cello-oligosaccharides from corncob residue by degradation-synthesis reactions.
Applied microbiology and biotechnology.
2024 Dec; 108(1):13. doi:
10.1007/s00253-023-12832-6. [PMID: 38170309] - Bianca Oliva, Josman Velasco, Gabriela Leila Berto, Igor Polikarpov, Leandro Cristante de Oliveira, Fernando Segato. Recombinant cellobiose dehydrogenase from Thermothelomyces thermophilus: Its functional characterization and applicability in cellobionic acid production.
Bioresource technology.
2024 Jun; 402(?):130763. doi:
10.1016/j.biortech.2024.130763. [PMID: 38692377] - Daguan Nong, Zachary K Haviland, Nerya Zexer, Sarah A Pfaff, Daniel J Cosgrove, Ming Tien, Charles T Anderson, William O Hancock. Single-molecule tracking reveals dual front door/back door inhibition of Cel7A cellulase by its product cellobiose.
Proceedings of the National Academy of Sciences of the United States of America.
2024 Apr; 121(18):e2322567121. doi:
10.1073/pnas.2322567121. [PMID: 38648472] - Frédéric Kerff, Samuel Jourdan, Isolde M Francis, Benoit Deflandre, Silvia Ribeiro Monteiro, Nudzejma Stulanovic, Rosemary Loria, Sébastien Rigali. Common scab disease: structural basis of elicitor recognition in pathogenic Streptomyces species.
Microbiology spectrum.
2023 Dec; 11(6):e0197523. doi:
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Journal of microbiology and biotechnology.
2023 Oct; 34(2):1-10. doi:
10.4014/jmb.2307.07004. [PMID: 38044713] - Pamela B Besada-Lombana, Wilfred Chen, Nancy A Da Silva. An extracellular glucose sensor for substrate-dependent secretion and display of cellulose-degrading enzymes.
Biotechnology and bioengineering.
2023 Sep; ?(?):. doi:
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International journal of molecular sciences.
2023 Jun; 24(11):. doi:
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Ecology.
2023 04; 104(4):e4005. doi:
10.1002/ecy.4005. [PMID: 36807130] - Jiuxing He, Meng Kong, Yuanchao Qian, Min Gong, Guohua Lv, Jiqing Song. Cellobiose elicits immunity in lettuce conferring resistance to Botrytis cinerea.
Journal of experimental botany.
2023 Feb; 74(3):1022-1038. doi:
10.1093/jxb/erac448. [PMID: 36385320] - Sree Kavya Penneru, Moumita Saharay, Marimuthu Krishnan. CelS-Catalyzed Processive Cellulose Degradation and Cellobiose Extraction for the Production of Bioethanol.
Journal of chemical information and modeling.
2022 12; 62(24):6628-6638. doi:
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Biological trace element research.
2022 Nov; 200(11):4865-4879. doi:
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Applied microbiology and biotechnology.
2022 Sep; 106(17):5629-5642. doi:
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Scientific reports.
2022 07; 12(1):13111. doi:
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Planta.
2022 Jun; 256(1):10. doi:
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Fungal genetics and biology : FG & B.
2022 04; 159(?):103673. doi:
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Microbial biotechnology.
2022 03; 15(3):915-930. doi:
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Advances in biochemical engineering/biotechnology.
2022; 181(?):73-122. doi:
10.1007/10_2021_200. [PMID: 35526186] - Benoit Deflandre, Nudzejma Stulanovic, Sören Planckaert, Sinaeda Anderssen, Beatrice Bonometti, Latifa Karim, Wouter Coppieters, Bart Devreese, Sébastien Rigali. The virulome of Streptomyces scabiei in response to cello-oligosaccharide elicitors.
Microbial genomics.
2022 01; 8(1):. doi:
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Microbiology spectrum.
2021 12; 9(3):e0167921. doi:
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mBio.
2021 12; 12(6):e0220621. doi:
10.1128/mbio.02206-21. [PMID: 34749527] - Sören Planckaert, Benoit Deflandre, Anne-Mare de Vries, Maarten Ameye, José C Martins, Kris Audenaert, Sébastien Rigali, Bart Devreese. Identification of Novel Rotihibin Analogues in Streptomyces scabies, Including Discovery of Its Biosynthetic Gene Cluster.
Microbiology spectrum.
2021 09; 9(1):e0057121. doi:
10.1128/spectrum.00571-21. [PMID: 34346752] - Xia Wang, Yudie Fu, Meiyan Wang, Guoqing Niu. Synthetic Cellobiose-Inducible Regulatory Systems Allow Tight and Dynamic Controls of Gene Expression in Streptomyces.
ACS synthetic biology.
2021 08; 10(8):1956-1965. doi:
10.1021/acssynbio.1c00152. [PMID: 34347449] - Parthasarathy Santhanam, Caroline Labbé, Luciano Gomes Fietto, Richard R Bélanger. A reassessment of flocculosin-mediated biocontrol activity of Pseudozyma flocculosa through CRISPR/Cas9 gene editing.
Fungal genetics and biology : FG & B.
2021 08; 153(?):103573. doi:
10.1016/j.fgb.2021.103573. [PMID: 34029708] - Sun-Ki Kim, Jordan Russell, Minseok Cha, Michael E Himmel, Yannick J Bomble, Janet Westpheling. Coexpression of a β-d-Xylosidase from Thermotoga maritima and a Family 10 Xylanase from Acidothermus cellulolyticus Significantly Improves the Xylan Degradation Activity of the Caldicellulosiruptor bescii Exoproteome.
Applied and environmental microbiology.
2021 06; 87(14):e0052421. doi:
10.1128/aem.00524-21. [PMID: 33990300] - Daiki Tanaka, Ken-Ichiro Ohnishi, Seiya Watanabe, Satoru Suzuki. Isolation of cellulase-producing Microbulbifer sp. from marine teleost blackfish (Girella melanichthys) intestine and the enzyme characterization.
The Journal of general and applied microbiology.
2021 Jun; 67(2):47-53. doi:
10.2323/jgam.2020.05.001. [PMID: 33250506] - Ai-Ping Pang, Haiyan Wang, Yongsheng Luo, Zihuayuan Yang, Zhiyu Liu, Zhao Wang, Bingzhi Li, Song Yang, Zhihua Zhou, Xiaolin Lu, Fu-Gen Wu, Zuhong Lu, Fengming Lin. Dissecting Cellular Function and Distribution of β-Glucosidases in Trichoderma reesei.
mBio.
2021 05; 12(3):. doi:
10.1128/mbio.03671-20. [PMID: 33975944] - Nadine Paßlack, Barbara Kohn, Wilfried Vahjen, Jürgen Zentek. Effects of dietary cellobiose on the intestinal microbiota and excretion of nitrogen metabolites in healthy adult dogs.
Journal of animal physiology and animal nutrition.
2021 May; 105(3):569-578. doi:
10.1111/jpn.13485. [PMID: 33480132] - Shangshang Sun, Xinlei Wei, Xigui Zhou, Chun You. Construction of an Artificial In Vitro Synthetic Enzymatic Platform for Upgrading Low-Cost Starch to Value-Added Disaccharides.
Journal of agricultural and food chemistry.
2021 Jan; 69(1):302-314. doi:
10.1021/acs.jafc.0c06936. [PMID: 33371670] - Chih-Hao Huang, Tzu-Ling Huang, Yu-Chang Liu, Ting-Chieh Chen, Shih-Ming Lin, Shyh-Yu Shaw, Ching-Chun Chang. Overexpression of a multifunctional β-glucosidase gene from thermophilic archaeon Sulfolobus solfataricus in transgenic tobacco could facilitate glucose release and its use as a reporter.
Transgenic research.
2020 12; 29(5-6):511-527. doi:
10.1007/s11248-020-00212-z. [PMID: 32776308] - Lan Liu, Jian-Yu Jiao, Bao-Zhu Fang, Ai-Ping Lv, Yu-Zhen Ming, Meng-Meng Li, Nimaichand Salam, Wen-Jun Li. Isolation of Clostridium from Yunnan-Tibet hot springs and description of Clostridium thermarum sp. nov. with lignocellulosic ethanol production.
Systematic and applied microbiology.
2020 Sep; 43(5):126104. doi:
10.1016/j.syapm.2020.126104. [PMID: 32847779] - May Thin Kyu, Shunsuke Nishio, Koki Noda, Bay Dar, San San Aye, Tsukasa Matsuda. Predominant secretion of cellobiohydrolases and endo-β-1,4-glucanases in nutrient-limited medium by Aspergillus spp. isolated from subtropical field.
Journal of biochemistry.
2020 Sep; 168(3):243-256. doi:
10.1093/jb/mvaa049. [PMID: 32330257] - Nadine Paßlack, Wilfried Vahjen, Jürgen Zentek. Impact of Dietary Cellobiose on the Fecal Microbiota of Horses.
Journal of equine veterinary science.
2020 08; 91(?):103106. doi:
10.1016/j.jevs.2020.103106. [PMID: 32684251] - Dan Liu, Yisong Liu, Duoduo Zhang, Xiaoting Chen, Qian Liu, Bentao Xiong, Lihui Zhang, Linfang Wei, Yifan Wang, Hao Fang, Johannes Liesche, Yahong Wei, N Louise Glass, Zhiqi Hao, Shaolin Chen. Quantitative Proteome Profiling Reveals Cellobiose-Dependent Protein Processing and Export Pathways for the Lignocellulolytic Response in Neurospora crassa.
Applied and environmental microbiology.
2020 07; 86(15):. doi:
10.1128/aem.00653-20. [PMID: 32471912] - Michael Brysch-Herzberg, Marizeth Groenewald, Dénes Dlauchy, Martin Seidel, Gábor Péter. Hyphopichia lachancei, f.a., sp. nov., a yeast species from diverse origins.
Antonie van Leeuwenhoek.
2020 Jun; 113(6):773-778. doi:
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International immunopharmacology.
2020 Jun; 83(?):106472. doi:
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International journal of molecular sciences.
2020 May; 21(11):. doi:
10.3390/ijms21113823. [PMID: 32481556] - Qingling Gou, Mou Tang, Yanan Wang, Wenting Zhou, Yi Liu, Zhiwei Gong. Deficiency of β-Glucosidase Beneficial for the Simultaneous Saccharification and Lipid Production by the Oleaginous Yeast Lipomyces starkeyi.
Applied biochemistry and biotechnology.
2020 Feb; 190(2):745-757. doi:
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PloS one.
2020; 15(8):e0226235. doi:
10.1371/journal.pone.0226235. [PMID: 32797046] - Weijun Wang, Tania Archbold, Joseph S Lam, Matthew S Kimber, Ming Z Fan. A processive endoglucanase with multi-substrate specificity is characterized from porcine gut microbiota.
Scientific reports.
2019 09; 9(1):13630. doi:
10.1038/s41598-019-50050-1. [PMID: 31541154] - Sun-Ki Kim, Daehwan Chung, Michael E Himmel, Yannick J Bomble, Janet Westpheling. Heterologous co-expression of two β-glucanases and a cellobiose phosphorylase resulted in a significant increase in the cellulolytic activity of the Caldicellulosiruptor bescii exoproteome.
Journal of industrial microbiology & biotechnology.
2019 May; 46(5):687-695. doi:
10.1007/s10295-019-02150-0. [PMID: 30783893] - Ning Liu, Hongjie Li, Marc G Chevrette, Lei Zhang, Lin Cao, Haokui Zhou, Xuguo Zhou, Zhihua Zhou, Phillip B Pope, Cameron R Currie, Yongping Huang, Qian Wang. Functional metagenomics reveals abundant polysaccharide-degrading gene clusters and cellobiose utilization pathways within gut microbiota of a wood-feeding higher termite.
The ISME journal.
2019 01; 13(1):104-117. doi:
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Scientific reports.
2018 12; 8(1):17824. doi:
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Journal of proteome research.
2018 11; 17(11):3837-3852. doi:
10.1021/acs.jproteome.8b00528. [PMID: 30229651] - Yaoyao Fu, Soo-Jin Yeom, Kil Koang Kwon, Jungwon Hwang, Haseong Kim, Eui-Jeon Woo, Dae-Hee Lee, Seung-Goo Lee. Structural and functional analyses of the cellulase transcription regulator CelR.
FEBS letters.
2018 08; 592(16):2776-2785. doi:
10.1002/1873-3468.13206. [PMID: 30062758] - Wei Xiong, Luis H Reyes, William E Michener, Pin-Ching Maness, Katherine J Chou. Engineering cellulolytic bacterium Clostridium thermocellum to co-ferment cellulose- and hemicellulose-derived sugars simultaneously.
Biotechnology and bioengineering.
2018 07; 115(7):1755-1763. doi:
10.1002/bit.26590. [PMID: 29537062] - Sara Casado López, Mao Peng, Tedros Yonatan Issak, Paul Daly, Ronald P de Vries, Miia R Mäkelä. Induction of Genes Encoding Plant Cell Wall-Degrading Carbohydrate-Active Enzymes by Lignocellulose-Derived Monosaccharides and Cellobiose in the White-Rot Fungus Dichomitus squalens.
Applied and environmental microbiology.
2018 06; 84(11):. doi:
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Journal of microbiology and biotechnology.
2018 Apr; 28(4):579-587. doi:
10.4014/jmb.1712.12037. [PMID: 29385667] - Sun-Ki Kim, Michael E Himmel, Yannick J Bomble, Janet Westpheling. Expression of a Cellobiose Phosphorylase from Thermotoga maritima in Caldicellulosiruptor bescii Improves the Phosphorolytic Pathway and Results in a Dramatic Increase in Cellulolytic Activity.
Applied and environmental microbiology.
2018 02; 84(3):. doi:
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The New phytologist.
2018 01; 217(2):713-725. doi:
10.1111/nph.14851. [PMID: 29044534] - Ana Solopova, Jan Kok, Oscar P Kuipers. Disruption of a Transcriptional Repressor by an Insertion Sequence Element Integration Leads to Activation of a Novel Silent Cellobiose Transporter in Lactococcus lactis MG1363.
Applied and environmental microbiology.
2017 Dec; 83(23):. doi:
10.1128/aem.01279-17. [PMID: 28970222] - Sun-Ki Kim, Daehwan Chung, Michael E Himmel, Yannick J Bomble, Janet Westpheling. Heterologous expression of a β-D-glucosidase in Caldicellulosiruptor bescii has a surprisingly modest effect on the activity of the exoproteome and growth on crystalline cellulose.
Journal of industrial microbiology & biotechnology.
2017 Dec; 44(12):1643-1651. doi:
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mBio.
2017 08; 8(4):. doi:
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Preparative biochemistry & biotechnology.
2017 Jul; 47(6):589-596. doi:
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BMC microbiology.
2017 06; 17(1):137. doi:
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Plant physiology.
2017 04; 173(4):2383-2398. doi:
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ACS synthetic biology.
2017 02; 6(2):206-210. doi:
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Applied microbiology and biotechnology.
2017 Feb; 101(3):1175-1188. doi:
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PloS one.
2017; 12(9):e0184730. doi:
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Applied and environmental microbiology.
2016 12; 82(24):7074-7085. doi:
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Scientific reports.
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International journal of systematic and evolutionary microbiology.
2016 Oct; 66(10):4132-4137. doi:
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Bioscience, biotechnology, and biochemistry.
2016 Aug; 80(8):1632-5. doi:
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Journal of microbiology and biotechnology.
2016 Jul; 26(7):1206-15. doi:
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Langmuir : the ACS journal of surfaces and colloids.
2016 06; 32(25):6343-59. doi:
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Scientific reports.
2016 06; 6(?):27144. doi:
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BMC microbiology.
2016 May; 16(?):91. doi:
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2016 May; 41(10):1855-1859. doi:
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Molecular microbiology.
2016 Apr; 100(2):289-302. doi:
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Protein expression and purification.
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JACC. Heart failure.
2016 Mar; 4(3):220-7. doi:
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BMC genomics.
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Neurobiology of aging.
2016 Feb; 38(?):215.e1-215.e12. doi:
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Applied microbiology and biotechnology.
2016 Feb; 100(4):1823-1831. doi:
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Bioresource technology.
2016 Jan; 200(?):1085-8. doi:
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Plant physiology.
2015 May; 168(1):3-17. doi:
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Bioprocess and biosystems engineering.
2015 May; 38(5):929-37. doi:
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2015 Feb; 6(2):e02018. doi:
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2014 Jan; 289(5):2610-9. doi:
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2014; 63(7):701-7. doi:
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Preparative biochemistry & biotechnology.
2013; 43(5):481-99. doi:
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2013; 8(9):e71068. doi:
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Metabolic engineering.
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Prikladnaia biokhimiia i mikrobiologiia.
2012 Nov; 52(6):584-9. doi:
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