Permethrin (BioDeep_00000002479)
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
(3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid
化学式: C21H20Cl2O3 (390.078943)
中文名称: 氯菊酯标准溶液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
InChI: InChI=1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
描述信息
Permethrin is only found in individuals that have used or taken this drug. It is a pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.Permethrin acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated. Delayed repolarization and paralysis of the pests are the consequences of this disturbance.
P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03A - Ectoparasiticides, incl. scabicides > P03AC - Pyrethrines, incl. synthetic compounds
D010575 - Pesticides > D007306 - Insecticides > D011722 - Pyrethrins
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
35 个代谢物同义名
(3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid; (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester; 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester; 3-Phenoxybenzyl-(+-)-cis,trans-2,2-dichlorovinyl-2,2-dimethyl-cyclopropylcarboxylic acid, ester; 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylate, (3-phenoxyphenyl) methyl ester; 3-Phenoxybenzyl-cis,trans-(1Rs)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate; (m-Phenoxybenzyl)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Permethrin, (trans-(+-))-isomer; Permethrin, trans-(1Rs)-isomer; Permethrin, (1S-trans)-isomer; Permethrin, (1R-trans)-isomer; Permethrin, (cis-(+-))-isomer; Permethrin, cis-(1Rs)-isomer; Permethrin, (1S-cis)-isomer; Permethrin, (1R-cis)-isomer; Permethrin, (trans)-isomer; Permethrin, (cis)-isomer; trans-(1Rs)-Permethrin; cis-(1Rs)-Permethrin; trans-permethrin; trans Permethrin; cis-permethrin; cis Permethrin; Permethrin; NRDC 147; NRDC-143; Nittifor; NRDC 143; NRDC-147; NRDC147; NRDC143; Elimite; Ambush
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:34911
- KEGG: C14388
- PubChem: 40326
- HMDB: HMDB0015604
- DrugBank: DB04930
- ChEMBL: CHEMBL1525
- Wikipedia: Permethrin
- MeSH: Permethrin
- chemspider: 36845
- CAS: 93389-07-2
- CAS: 52341-32-9
- CAS: 82523-59-9
- CAS: 52645-53-1
- CAS: 52341-33-0
- PMhub: MS000002760
- PubChem: 17395388
- NIKKAJI: J10.127C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ming-Hui Shi, Yi Yan, Xi Niu, Jia-Fu Wang, Sheng Li. GPR39-mediated ERK1/2 signaling reduces permethrin-induced proliferation of estrogen receptor α-negative cells.
Ecotoxicology and environmental safety.
2024 May; 276(?):116303. doi:
10.1016/j.ecoenv.2024.116303. [PMID: 38599157] - Timothy A Bargar, Michelle L Hladik. Permethrin Contamination of Sawgrass Marshes and Potential Risk for the Imperiled Klot's Skipper Butterfly (Euphyes pilatka klotsi).
Environmental toxicology and chemistry.
2024 Feb; 43(2):267-278. doi:
10.1002/etc.5783. [PMID: 37921583] - Damla Himtaş, Emine Yalçin, Kültiğin Çavuşoğlu, Ali Acar. In-vivo and in-silico studies to identify toxicity mechanisms of permethrin with the toxicity-reducing role of ginger.
Environmental science and pollution research international.
2024 Feb; 31(6):9272-9287. doi:
10.1007/s11356-023-31729-5. [PMID: 38191734] - Fred A Ashu, Caroline Fouet, Marilene M Ambadiang, Véronique Penlap-Beng, Colince Kamdem. Vegetable oil-based surfactants are adjuvants that enhance the efficacy of neonicotinoid insecticides and can bias susceptibility testing in adult mosquitoes.
PLoS neglected tropical diseases.
2023 Nov; 17(11):e0011737. doi:
10.1371/journal.pntd.0011737. [PMID: 37976311] - Govindaraju Ramkumar, Ranganathan Muthusamy, Mathiyazhagan Narayanan, Muthugoundar Subramanian Shivakumar, Eliningaya J Kweka. Overexpression of cytochrome P450 and esterase genes involved in permethrin resistance in larvae and adults of Culex quinquefasciatus.
Parasitology research.
2023 Oct; ?(?):. doi:
10.1007/s00436-023-08010-2. [PMID: 37874391] - Julee Verma, Ajit Kumar Rai, Neeraj Kumar Satija. Autophagy perturbation upon acute pyrethroid treatment impacts adipogenic commitment of mesenchymal stem cells.
Pesticide biochemistry and physiology.
2023 Sep; 195(?):105566. doi:
10.1016/j.pestbp.2023.105566. [PMID: 37666621] - Yifan Wang, Xin Wang, Dylan J Brown, Mengru An, Rui-De Xue, Nannan Liu. Insecticide resistance: Status and potential mechanisms in Aedes aegypti.
Pesticide biochemistry and physiology.
2023 Sep; 195(?):105577. doi:
10.1016/j.pestbp.2023.105577. [PMID: 37666603] - Yi Yan, Tian Wen Long, Xi Niu, Jia Fu Wang, Sheng Li. MiR-96-5p is involved in permethrin-promoted proliferation and migration of breast cancer cells.
Acta biochimica Polonica.
2023 Aug; ?(?):. doi:
10.18388/abp.2020_6533. [PMID: 37595068] - Agata Borowik, Jadwiga Wyszkowska, Magdalena Zaborowska, Jan Kucharski. Microbial Diversity and Enzyme Activity as Indicators of Permethrin-Exposed Soil Health.
Molecules (Basel, Switzerland).
2023 Jun; 28(12):. doi:
10.3390/molecules28124756. [PMID: 37375310] - M M Noel Reynoso, Eduardo N Zerba, Raúl A Alzogaray. Eugenol and menthol synergize the toxicity of permethrin in the blood-sucking bug, Triatoma infestans.
Acta tropica.
2023 May; 241(?):106900. doi:
10.1016/j.actatropica.2023.106900. [PMID: 36940855] - Dongyan Feng, Le Ren, Jiaqi Wu, Lingling Guo, Zhitao Han, Jingjing Yang, Wei Xie, Yanbing Wang, Fanxing Xu, Xin Su, Dahong Li, Hao Cao. Permethrin as a Potential Furin Inhibitor through a Novel Non-Competitive Allosteric Inhibition.
Molecules (Basel, Switzerland).
2023 Feb; 28(4):. doi:
10.3390/molecules28041883. [PMID: 36838867] - Ming Li, Xuechun Feng, William R Reid, Fang Tang, Nannan Liu. Multiple-P450 Gene Co-Up-Regulation in the Development of Permethrin Resistance in the House Fly, Musca domestica.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043170. [PMID: 36834582] - Agata Borowik, Jadwiga Wyszkowska, Magdalena Zaborowska, Jan Kucharski. The Impact of Permethrin and Cypermethrin on Plants, Soil Enzyme Activity, and Microbial Communities.
International journal of molecular sciences.
2023 Feb; 24(3):. doi:
10.3390/ijms24032892. [PMID: 36769219] - Vahideh Mahdavi, Sharaf S Omar, Tayebeh Zeinali, Parisa Sadighara, Yadolah Fakhri. Carcinogenic and non-carcinogenic risk assessment induced by pesticide residues in fresh pistachio in Iran based on Monte Carlo simulation.
Environmental science and pollution research international.
2023 Jan; ?(?):. doi:
10.1007/s11356-023-25143-0. [PMID: 36626050] - Manachai Yingklang, Chadaporn Nuchjangreed Gordon, Patchana Hengboriboonpong Jaidee, Phonpilas Thongpon, Somchai Pinlaor. Comparative efficacy of chemical and botanical pediculicides in Thailand and 4\% dimeticone against head louse, Pediculus humanus capitis.
PloS one.
2023; 18(6):e0287616. doi:
10.1371/journal.pone.0287616. [PMID: 37352268] - Natacha Tessier, Romain Boissonnot, Virginie Desvignes, Marie Fröchen, Mathilde Merlo, Olivier Blanchard, Cécile Chevrier, Laurence Guldner, Corinne Mandin, Ohri Yamada, Jean-Luc Volatier. Use and storage of pesticides at home in France (the Pesti'home survey 2014).
Environmental research.
2023 01; 216(Pt 2):114452. doi:
10.1016/j.envres.2022.114452. [PMID: 36257454] - Tiyyabah Khan, Hafiz Azhar Ali Khan, Muhammad Saleem Haider, Waheed Anwar, Adnan Akhter. Selection for resistance to pirimiphos-methyl, permethrin and spinosad in a field strain of Sitophilus oryzae: resistance risk assessment, cross-resistance potential and synergism of insecticides.
Environmental science and pollution research international.
2022 Nov; ?(?):. doi:
10.1007/s11356-022-24325-6. [PMID: 36422779] - Yifan Wang, Mengru An, Kelly M Stevens, Nannan Liu. Insecticide Resistance in Alabama Populations of the Mosquito Aedes albopictus.
Journal of medical entomology.
2022 09; 59(5):1678-1686. doi:
10.1093/jme/tjac085. [PMID: 35851609] - Nissaf Aoiadni, Hajer Jdidi, Abdelfattah El Feki, Hamadi Fetoui, Fatma Ghorbel Koubaa. Mitochondrial bioenergetics and redox dysfunction in nephrotoxicity induced by pyrethroid permethrin are ameliorated by flavonoid-rich fraction.
Environmental science and pollution research international.
2022 Sep; 29(42):63973-63987. doi:
10.1007/s11356-022-20350-7. [PMID: 35469380] - Krishna Neupane, Vivek K Ojha, Jason B Oliver, Karla M Addesso, Fulya Baysal-Gurel. Integration of Control Strategies to Optimize Management of Ambrosia Beetles (Coleoptera: Curculionidae, Scolytinae) and Phytophthora Root Rot (Peronosporales: Peronosporaceae) in Flowering Dogwoods (Cornalaes: Cornaceae) After Simulated Flooding.
Journal of economic entomology.
2022 08; 115(4):1213-1230. doi:
10.1093/jee/toac093. [PMID: 35766626] - Nissaf Aoiadni, Nour Chiab, Hajer Jdidi, Radhia Gargouri Bouzid, Abdelfattah El Feki, Hamadi Fetoui, Fatma Ghorbel Koubaa. The pyrethroid insecticide permethrin confers hepatotoxicity through DNA damage and mitochondria-associated apoptosis induction in rat: Palliative benefits of Fumaria officinalis.
Journal of biochemical and molecular toxicology.
2022 Jul; ?(?):e23172. doi:
10.1002/jbt.23172. [PMID: 35861702] - Tiyyabah Khan, Muhammad Saleem Haider, Hafiz Azhar Ali Khan. Resistance to grain protectants and synergism in Pakistani strains of Sitophilus oryzae (Coleoptera: Curculionidae).
Scientific reports.
2022 07; 12(1):12401. doi:
10.1038/s41598-022-16412-y. [PMID: 35859096] - Revocatus Yohana, Paulo S Chisulumi, Winifrida Kidima, Azar Tahghighi, Naseh Maleki-Ravasan, Eliningaya J Kweka. Anti-mosquito properties of Pelargonium roseum (Geraniaceae) and Juniperus virginiana (Cupressaceae) essential oils against dominant malaria vectors in Africa.
Malaria journal.
2022 Jul; 21(1):219. doi:
10.1186/s12936-022-04220-8. [PMID: 35836226] - Ying-Jian Sun, Yu-Jie Liang, Lin Yang, Ding-Xin Long, Hui-Ping Wang, Yi-Jun Wu. Long-term low-dose exposure of permethrin induces liver and kidney damage in rats.
BMC pharmacology & toxicology.
2022 Jul; 23(1):46. doi:
10.1186/s40360-022-00586-2. [PMID: 35804463] - Christina Natalina Silalahi, Wu-Chun Tu, Niann-Tai Chang, G Veera Singham, Intan Ahmad, Kok-Boon Neoh. Insecticide Resistance Profiles and Synergism of Field Aedes aegypti from Indonesia.
PLoS neglected tropical diseases.
2022 06; 16(6):e0010501. doi:
10.1371/journal.pntd.0010501. [PMID: 35666774] - Xingtao Qie, Yuzhe Du, Ahmed A A Aioub, Ke Dong, Zhaonong Hu. Negative cross-resistance of a pyrethroid-resistant Drosophila mutant to Phryma leptostachya-derived haedoxan A.
Insect science.
2022 Jun; 29(3):817-826. doi:
10.1111/1744-7917.12973. [PMID: 34547832] - Heather L Kopsco, Thomas N Mather. Tick-Borne Disease Prevention Behaviors Among Participants in a Tick Surveillance System Compared with a Sample Of Master Gardeners.
Journal of community health.
2022 04; 47(2):246-256. doi:
10.1007/s10900-021-01041-9. [PMID: 34727297] - Stephanie L Richards, Jeffrey Driver, Megan C Dyer, Thomas N Mather, Sheana Funkhouser, Cedar Mitchell, Jo Anne Balanay, Avian White, Steven Meshnick. Assessing Durability and Safety of Permethrin Impregnated Uniforms Used by Outdoor Workers to Prevent Tick Bites after One Year of Use.
Journal of medical entomology.
2022 03; 59(2):615-622. doi:
10.1093/jme/tjab216. [PMID: 34958094] - Youhui Gong, Ming Li, Ting Li, Nannan Liu. Molecular and functional characterization of three novel carboxylesterases in the detoxification of permethrin in the mosquito, Culex quinquefasciatus.
Insect science.
2022 Feb; 29(1):199-214. doi:
10.1111/1744-7917.12927. [PMID: 34048147] - Tahsin Çağdaş Akaslan, Ömer Mert, Özlem Su Küçük. Scabies increase during the COVID-19 pandemic: should we change our treatment strategy during the pandemic?.
Annals of parasitology.
2022; 68(1):35-38. doi:
10.17420/ap6801.405. [PMID: 35436399] - Anouar Feriani, Mariano Bizzarri, Meriam Tir, Nouf Aldawood, Hussah Alobaid, Mohamed Salah Allagui, Waleed Dahmash, Nizar Tlili, Kais Mnafgui, Saleh Alwasel, Abdel Halim Harrath. High-fat diet-induced aggravation of cardiovascular impairment in permethrin-treated Wistar rats.
Ecotoxicology and environmental safety.
2021 Oct; 222(?):112461. doi:
10.1016/j.ecoenv.2021.112461. [PMID: 34224971] - Bruce A Buchholz, Ki Chang Ahn, Huazhang Huang, Shirley J Gee, Benjamin J Stewart, Ted J Ognibene, Bruce D Hammock. Pharmacokinetics, Metabolite Measurement, and Biomarker Identification of Dermal Exposure to Permethrin Using Accelerator Mass Spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology.
2021 08; 183(1):49-59. doi:
10.1093/toxsci/kfab082. [PMID: 34460930] - Rachid Jellali, Sebastien Jacques, Amal Essaouiba, Françoise Gilard, Franck Letourneur, Bertrand Gakière, Cécile Legallais, Eric Leclerc. Investigation of steatosis profiles induced by pesticides using liver organ-on-chip model and omics analysis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2021 Jun; 152(?):112155. doi:
10.1016/j.fct.2021.112155. [PMID: 33775782] - Ting Yang, Ting Li, Xuechun Feng, Ming Li, Shikai Liu, Nannan Liu. Multiple cytochrome P450 genes: conferring high levels of permethrin resistance in mosquitoes, Culex quinquefasciatus.
Scientific reports.
2021 04; 11(1):9041. doi:
10.1038/s41598-021-88121-x. [PMID: 33907243] - Andrew P Derby, Neil W Fuller, Kara E Huff Hartz, Amelie Segarra, Richard E Connon, Susanne M Brander, Michael J Lydy. Trophic transfer, bioaccumulation and transcriptomic effects of permethrin in inland silversides, Menidia beryllina, under future climate scenarios.
Environmental pollution (Barking, Essex : 1987).
2021 Apr; 275(?):116545. doi:
10.1016/j.envpol.2021.116545. [PMID: 33578317] - Mersimine F M Kouamo, Sulaiman S Ibrahim, Jack Hearn, Jacob M Riveron, Michael Kusimo, Magellan Tchouakui, Terence Ebai, Williams Tchapga, Murielle J Wondji, Helen Irving, Thaddée Boudjeko, Fabrice F Boyom, Charles S Wondji. Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa.
Genes.
2021 04; 12(4):. doi:
10.3390/genes12040561. [PMID: 33924421] - Nissaf Aoiadni, Houda Ayadi, Hajer Jdidi, Manel Naifar, Sami Maalej, Fatma Ayadi Makni, Abdelfattah El Feki, Hamadi Fetoui, Fatma Ghorbel Koubaa. Flavonoid-rich fraction attenuates permethrin-induced toxicity by modulating ROS-mediated hepatic oxidative stress and mitochondrial dysfunction ex vivo and in vivo in rat.
Environmental science and pollution research international.
2021 Feb; 28(8):9290-9312. doi:
10.1007/s11356-020-11250-9. [PMID: 33136269] - Anouar Feriani, Meriam Tir, Rafik Hachani, Mohamed Salah Allagui, Nizar Tlili, Saber Nahdi, Saleh Alwasel, Abdel Halim Harrath. Permethrin induced arterial retention of native and oxidized LDL in rats by promoting inflammation, oxidative stress and affecting LDL receptors, and collagen genes.
Ecotoxicology and environmental safety.
2021 Jan; 207(?):111269. doi:
10.1016/j.ecoenv.2020.111269. [PMID: 32911180] - Paul Quindroit, Amélie Crépet, Céline Brochot. Estimating human exposure to pyrethroids' mixtures from biomonitoring data using physiologically based pharmacokinetic modeling.
Environmental research.
2021 01; 192(?):110281. doi:
10.1016/j.envres.2020.110281. [PMID: 33031810] - Ikkei Shikano. Efficacy of a Fungal Biopesticide for Bed Bug Management Is Influenced by the Toxicity and Associated Behavioral Avoidance of Harborages on Insecticide-Impregnated Box Spring Covers.
Journal of economic entomology.
2020 12; 113(6):2850-2857. doi:
10.1093/jee/toaa227. [PMID: 33001173] - Mélanie Blanc, Bettie Cormier, Tuulia Hyötyläinen, Martin Krauss, Nikolai Scherbak, Xavier Cousin, Steffen H Keiter. Multi- and transgenerational effects following early-life exposure of zebrafish to permethrin and coumarin 47: Impact on growth, fertility, behavior and lipid metabolism.
Ecotoxicology and environmental safety.
2020 Dec; 205(?):111348. doi:
10.1016/j.ecoenv.2020.111348. [PMID: 32979803] - Likui Wang, Lianyun Lin, Hao Wang, Wenbo Duan, Fen Li, Kun Zhang, Peng Cao, Zhiguang Yuchi, Shaoying Wu. Two classic mutations in the linker-helix IIL45 and segment IIS6 of Apolygus lucorum sodium channel confer pyrethroid resistance.
Pest management science.
2020 Dec; 76(12):3954-3964. doi:
10.1002/ps.5944. [PMID: 32506650] - Jennifer L M Thorson, Daniel Beck, Millissia Ben Maamar, Eric E Nilsson, Michael K Skinner. Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease.
Environmental health : a global access science source.
2020 11; 19(1):109. doi:
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Journal of economic entomology.
2020 10; 113(5):2418-2426. doi:
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Parasites & vectors.
2020 Aug; 13(1):423. doi:
10.1186/s13071-020-04296-8. [PMID: 32811561] - Jun-Hyung Tak, Quentin Robert Renaud Coquerel, Maia Tsikolia, Ulrich R Bernier, Kenneth Linthicum, Jeffrey R Bloomquist. Screening for Enhancement of Permethrin Toxicity by Plant Essential Oils Against Adult Females of the Yellow Fever Mosquito (Diptera: Culicidae).
Journal of medical entomology.
2020 07; 57(4):1149-1156. doi:
10.1093/jme/tjaa014. [PMID: 32020196] - Alexis L Maule, Kristin J Heaton, Bruce Cadarette, Kathryn M Taylor, Katelyn I Guerriere, Caitlin C Haven, Matthew M Scarpaci, Robert W Kenefick, Maria Ospina, Antonia M Calafat, Susan P Proctor. Effect of Environmental Temperature and Humidity on Permethrin Biomarkers of Exposure in U.S. Soldiers Wearing Permethrin-Treated Uniforms.
The American journal of tropical medicine and hygiene.
2020 06; 102(6):1455-1462. doi:
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Journal of economic entomology.
2020 04; 113(2):896-904. doi:
10.1093/jee/toz323. [PMID: 31820778] - Jing Pang, Tanzir Mortuza, Catherine A White, Srinavasa Muralidhara, Brian S Cummings, James V Bruckner. Toxicokinetics of cis- and trans-Permethrin: Influence of Isomer, Maturation, and Sex.
Toxicological sciences : an official journal of the Society of Toxicology.
2020 03; 174(1):25-37. doi:
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Journal of occupational and environmental medicine.
2020 03; 62(3):210-216. doi:
10.1097/jom.0000000000001801. [PMID: 31895734] - Yu-Jie Liang, Pan Wang, Ding-Xin Long, Hui-Ping Wang, Ying-Jian Sun, Yi-Jun Wu. The progressive alteration of urine metabolomic profiles of rats following long-term and low-dose exposure to permethrin.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2020 Feb; 25(1):94-99. doi:
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Analytical and bioanalytical chemistry.
2019 Dec; 411(30):8043-8052. doi:
10.1007/s00216-019-02157-7. [PMID: 31748895] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Utsav Joshi, Andrew Pearson, James E Evans, Heather Langlois, Nicole Saltiel, Joseph Ojo, Nancy Klimas, Kimberly Sullivan, Andrew P Keegan, Sarah Oberlin, Teresa Darcey, Adam Cseresznye, Balaram Raya, Daniel Paris, Bruce Hammock, Natalia Vasylieva, Surat Hongsibsong, Lawrence J Stern, Fiona Crawford, Michael Mullan, Laila Abdullah. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness.
Brain, behavior, and immunity.
2019 10; 81(?):545-559. doi:
10.1016/j.bbi.2019.07.015. [PMID: 31325531] - Albert E Mayfield, Jennifer Juzwik, Jamison Scholer, John D Vandenberg, Adam Taylor. Effect of Bark Application With Beauveria bassiana and Permethrin Insecticide on the Walnut Twig Beetle (Coleoptera: Curculionidae) in Black Walnut Bolts.
Journal of economic entomology.
2019 09; 112(5):2493-2496. doi:
10.1093/jee/toz150. [PMID: 31141149] - Ting Li, Nannan Liu. Role of the G-Protein-Coupled Receptor Signaling Pathway in Insecticide Resistance.
International journal of molecular sciences.
2019 Sep; 20(17):. doi:
10.3390/ijms20174300. [PMID: 31484301] - Louise Dalsager, Bettina Fage-Larsen, Niels Bilenberg, Tina Kold Jensen, Flemming Nielsen, Henriette Boye Kyhl, Philippe Grandjean, Helle Raun Andersen. Maternal urinary concentrations of pyrethroid and chlorpyrifos metabolites and attention deficit hyperactivity disorder (ADHD) symptoms in 2-4-year-old children from the Odense Child Cohort.
Environmental research.
2019 09; 176(?):108533. doi:
10.1016/j.envres.2019.108533. [PMID: 31229776] - Pankaj Sethi, James V Bruckner, Tanzir B Mortuza, Brian S Cummings, Srinivasa Muralidhara, Catherine A White. Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats.
Drug metabolism and disposition: the biological fate of chemicals.
2019 09; 47(9):941-948. doi:
10.1124/dmd.118.085464. [PMID: 31248885] - Prabhakar Mishra, Sneha Dutta, Manidipa Haldar, Priyanka Dey, Drishty Kumar, Amitava Mukherjee, Natarajan Chandrasekaran. Enhanced mosquitocidal efficacy of colloidal dispersion of pyrethroid nanometric emulsion with benignity towards non-target species.
Ecotoxicology and environmental safety.
2019 Jul; 176(?):258-269. doi:
10.1016/j.ecoenv.2019.03.096. [PMID: 30939406] - Laura Hedges, Susan Brown, Audrey Vardy, Edward Doyle, Miyoung Yoon, Thomas G Osimitz, Brian G Lake. Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Apr; 49(4):388-396. doi:
10.1080/00498254.2018.1451011. [PMID: 29537356] - Alexis L Maule, Matthew M Scarpaci, Susan P Proctor. Urinary concentrations of permethrin metabolites in US Army personnel in comparison with the US adult population, occupationally exposed cohorts, and other general populations.
International journal of hygiene and environmental health.
2019 04; 222(3):355-363. doi:
10.1016/j.ijheh.2019.02.005. [PMID: 30852112] - Nicole R Laferriere, Wendy E Kurata, Cary T Grayson, Kelsey M Stecklow, Lisa M Pierce. Inhibition of microRNA-124-3p as a novel therapeutic strategy for the treatment of Gulf War Illness: Evaluation in a rat model.
Neurotoxicology.
2019 03; 71(?):16-30. doi:
10.1016/j.neuro.2018.11.008. [PMID: 30503814] - Jason S Yang, Weipeng Qi, Renalison Farias-Pereira, Stephanie Choi, John M Clark, Daeyoung Kim, Yeonhwa Park. Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2019 Mar; 125(?):595-604. doi:
10.1016/j.fct.2019.02.005. [PMID: 30738135] - Kristin M Sullivan, Alison Poffley, Sheana Funkhouser, Jeffrey Driver, John Ross, Maria Ospina, Antonia M Calafat, Charles B Beard, Avian White, Jo Anne Balanay, Stephanie Richards, Megan Dyer, Thomas N Mather, Steven Meshnick. Bioabsorption and effectiveness of long-lasting permethrin-treated uniforms over three months among North Carolina outdoor workers.
Parasites & vectors.
2019 Jan; 12(1):52. doi:
10.1186/s13071-019-3314-1. [PMID: 30674346] - Mauro Eugênio Medina Nunes, Lucia Emanueli Schimith, Dennis Guilherme da Costa-Silva, Andressa Rubim Lopes, Luana Paganotto Leandro, Illana Kemmerich Martins, Renata Siqueira de Mello, Diane Duarte Hartmann, Nelson Rodrigues de Carvalho, Pamela Carvalho da Rosa, Rafael Trevisan, Richard Thomas Di Giulio, Thaís Posser, Jeferson Luis Franco. Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish.
Oxidative medicine and cellular longevity.
2019; 2019(?):9149203. doi:
10.1155/2019/9149203. [PMID: 31827707] - Laura Bordoni, Rosita Gabbianelli, Donatella Fedeli, Dennis Fiorini, Ina Bergheim, Cheng Jun Jin, Lisa Marinelli, Antonio Di Stefano, Cinzia Nasuti. Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson's disease.
PloS one.
2019; 14(10):e0223238. doi:
10.1371/journal.pone.0223238. [PMID: 31600256] - Susan P Proctor, Matthew M Scarpaci, Alexis L Maule, Kristin J Heaton, Kathryn Taylor, Caitlin C Haven, Jennifer Rood, Maria Ospina, Antonia M Calafat. Role of body composition and physical activity on permethrin urinary biomarker concentrations while wearing treated military uniforms.
Toxicology letters.
2018 Dec; 299(?):210-217. doi:
10.1016/j.toxlet.2018.10.001. [PMID: 30292884] - Luis Carlos Martínez, Angelica Plata-Rueda, Guilherme da Silva Neves, Wagner Gonzaga Gonçalves, José Cola Zanuncio, Hakan Bozdoğan, José Eduardo Serrão. Permethrin induces histological and cytological changes in the midgut of the predatory bug, Podisus nigrispinus.
Chemosphere.
2018 Dec; 212(?):629-637. doi:
10.1016/j.chemosphere.2018.08.134. [PMID: 30173109] - Jason S Yang, Steven Symington, John M Clark, Yeonhwa Park. Permethrin, a pyrethroid insecticide, regulates ERK1/2 activation through membrane depolarization-mediated pathway in HepG2 hepatocytes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2018 Nov; 121(?):387-395. doi:
10.1016/j.fct.2018.09.009. [PMID: 30205134] - Jonathan Côté, Michèle Bouchard. Dose reconstruction in workers exposed to two major pyrethroid pesticides and determination of biological reference values using a toxicokinetic model.
Journal of exposure science & environmental epidemiology.
2018 11; 28(6):599-614. doi:
10.1038/s41370-017-0004-y. [PMID: 29284785] - Michael T Williams, Arnold Gutierrez, Charles V Vorhees. Effects of Acute Exposure of Permethrin in Adult and Developing Sprague-Dawley Rats on Acoustic Startle Response and Brain and Plasma Concentrations.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 10; 165(2):361-371. doi:
10.1093/toxsci/kfy142. [PMID: 29893952] - Rachid Jellali, Françoise Gilard, Vittoria Pandolfi, Audrey Legendre, Marie-José Fleury, Patrick Paullier, Cécile Legallais, Eric Leclerc. Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures.
Journal of applied toxicology : JAT.
2018 08; 38(8):1121-1134. doi:
10.1002/jat.3624. [PMID: 29659035] - Jessica M Abbate, Ettore Napoli, Francesca Arfuso, Gabriella Gaglio, Salvatore Giannetto, Lenaig Halos, Frederic Beugnet, Emanuele Brianti. Six-month field efficacy and safety of the combined treatment of dogs with Frontline Tri-Act® and NexGard Spectra®.
Parasites & vectors.
2018 Jul; 11(1):425. doi:
10.1186/s13071-018-2957-7. [PMID: 30012179] - Ting Li, Nannan Liu. The Function of G-Protein-Coupled Receptor-Regulatory Cascade in Southern House Mosquitoes (Diptera: Culicidae).
Journal of medical entomology.
2018 06; 55(4):862-870. doi:
10.1093/jme/tjy022. [PMID: 29608693] - William R Reid, Lee Zhang, Youhui Gong, Ting Li, Nannan Liu. Gene expression profiles of the Southern house mosquito Culex quinquefasciatus during exposure to permethrin.
Insect science.
2018 Jun; 25(3):439-453. doi:
10.1111/1744-7917.12438. [PMID: 28074632] - Alyssa M Piccolomini, Shavonn R Whiten, Michelle L Flenniken, Kevin M O'Neill, Robert K D Peterson. Acute Toxicity of Permethrin, Deltamethrin, and Etofenprox to the Alfalfa Leafcutting Bee.
Journal of economic entomology.
2018 05; 111(3):1001-1005. doi:
10.1093/jee/toy014. [PMID: 29444244] - Rachid Jellali, Perrine Zeller, Françoise Gilard, Audrey Legendre, Marie José Fleury, Sébastien Jacques, Guillaume Tcherkez, Eric Leclerc. Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: Metabolomics and gene expression study.
Environmental toxicology and pharmacology.
2018 Apr; 59(?):1-12. doi:
10.1016/j.etap.2018.02.004. [PMID: 29477483] - Eunice L Yuh, Iain Keir. Hypertriglyceridemia and transient corneal lipidosis in a cat following intravenous lipid therapy for permethrin toxicosis.
The Canadian veterinary journal = La revue veterinaire canadienne.
2018 02; 59(2):155-158. doi:
". [PMID: 29386675] - Natalie M Bowman, Kristin Akialis, Grayson Cave, Roberto Barrera, Charles S Apperson, Steven R Meshnick. Pyrethroid insecticides maintain repellent effect on knock-down resistant populations of Aedes aegypti mosquitoes.
PloS one.
2018; 13(5):e0196410. doi:
10.1371/journal.pone.0196410. [PMID: 29763445] - Matteo Anaclerio, Marco Pellizzoni, Valeria Todeschini, David Kane, Ahmad Hanafi, Marco Trevisan, Luigi Lucini. Efficacy and residues of permethrin-incorporated nets used to protect maize grains post-harvest.
Pest management science.
2018 Jan; 74(1):240-245. doi:
10.1002/ps.4709. [PMID: 28834586] - Wangxin Tang, Di Wang, Jiaqi Wang, Zhengwen Wu, Lingyu Li, Mingli Huang, Shaohui Xu, Dongyun Yan. Pyrethroid pesticide residues in the global environment: An overview.
Chemosphere.
2018 Jan; 191(?):990-1007. doi:
10.1016/j.chemosphere.2017.10.115. [PMID: 29145144] - Xiao Xiao, Quancai Sun, Yoo Kim, Szu-Hao Yang, Weipeng Qi, Daeyoung Kim, Kyong Sup Yoon, John M Clark, Yeonhwa Park. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2018 Jan; 111(?):405-416. doi:
10.1016/j.fct.2017.11.047. [PMID: 29175578] - Laura Bille, Giovanni Binato, Claudio Gabrieli, Amedeo Manfrin, Francesco Pascoli, Tobia Pretto, Anna Toffan, Manuela Dalla Pozza, Roberto Angeletti, Giuseppe Arcangeli. First report of a fish kill episode caused by pyrethroids in Italian freshwater.
Forensic science international.
2017 Dec; 281(?):176-182. doi:
10.1016/j.forsciint.2017.10.040. [PMID: 29190591] - Haina Sun, Shinji Kasai, Jeffrey G Scott. Two novel house fly Vssc mutations, D600N and T929I, give rise to new insecticide resistance alleles.
Pesticide biochemistry and physiology.
2017 Nov; 143(?):116-121. doi:
10.1016/j.pestbp.2017.08.013. [PMID: 29183579] - Mohaddeseh Abouhosseini Tabari, Mohammad Reza Youssefi, Filippo Maggi, Giovanni Benelli. Toxic and repellent activity of selected monoterpenoids (thymol, carvacrol and linalool) against the castor bean tick, Ixodes ricinus (Acari: Ixodidae).
Veterinary parasitology.
2017 Oct; 245(?):86-91. doi:
10.1016/j.vetpar.2017.08.012. [PMID: 28969843] - Shirin Hooshfar, Michael G Bartlett. Bioanalytical methods for the quantification of cis-permethrin and trans-permethrin in biological samples.
Bioanalysis.
2017 Oct; 9(19):1433-1435. doi:
10.4155/bio-2017-0157. [PMID: 29056073] - Cláudio E T Parente, Julliana Lestayo, Yago S Guida, Claudio E Azevedo-Silva, João Paulo M Torres, Rodrigo O Meire, Olaf Malm. Pyrethroids in chicken eggs from commercial farms and home production in Rio de Janeiro: Estimated daily intake and diastereomeric selectivity.
Chemosphere.
2017 Oct; 184(?):1261-1269. doi:
10.1016/j.chemosphere.2017.06.109. [PMID: 28672725] - Haina Sun, Nicolas Buchon, Jeffrey G Scott. Mdr65 decreases toxicity of multiple insecticides in Drosophila melanogaster.
Insect biochemistry and molecular biology.
2017 10; 89(?):11-16. doi:
10.1016/j.ibmb.2017.08.002. [PMID: 28803989] - Xiao Xiao, Yoo Kim, Daeyoung Kim, Kyong Sup Yoon, John M Clark, Yeonhwa Park. Permethrin alters glucose metabolism in conjunction with high fat diet by potentiating insulin resistance and decreases voluntary activities in female C57BL/6J mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Oct; 108(Pt A):161-170. doi:
10.1016/j.fct.2017.07.053. [PMID: 28757463] - Shirin Hooshfar, Darren R Gullick, Michael R Linzey, Tanzir Mortuza, Mona Hamdy Abdel Rahman, Clinton A Rogers, James V Bruckner, Catherine A White, Michael G Bartlett. Simultaneous determination of cis-permethrin and trans-permethrin in rat plasma and brain tissue using gas chromatography-negative chemical ionization mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Aug; 1060(?):291-299. doi:
10.1016/j.jchromb.2017.06.019. [PMID: 28651172] - Gabriela Ullio-Gamboa, Santiago Palma, Jean Pierre Benoit, Daniel Allemandi, María Inés Picollo, Ariel Ceferino Toloza. Ivermectin lipid-based nanocarriers as novel formulations against head lice.
Parasitology research.
2017 Aug; 116(8):2111-2117. doi:
10.1007/s00436-017-5510-2. [PMID: 28523490] - Manoj Amaraneni, Jing Pang, James V Bruckner, Srinivasa Muralidhara, Tanzir B Mortuza, Darren Gullick, Shirin Hooshfar, Catherine A White, Brian S Cummings. Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis- and Trans-Permethrin.
Journal of pharmaceutical sciences.
2017 08; 106(8):2144-2151. doi:
10.1016/j.xphs.2017.04.024. [PMID: 28445697] - Pan Wang, Ming-Yuan Xu, Yu-Jie Liang, Hui-Ping Wang, Ying-Jian Sun, Ding-Xin Long, Yi-Jun Wu. Subchronic toxicity of low dose propoxur, permethrin, and their combination on the redox status of rat liver.
Chemico-biological interactions.
2017 Jun; 272(?):21-27. doi:
10.1016/j.cbi.2017.04.023. [PMID: 28456543] - Leah J E Pryor, Joseph M Casto. Ectoparasites as developmental stressors: Effects on somatic and physiological development.
Journal of experimental zoology. Part A, Ecological and integrative physiology.
2017 06; 327(5):311-321. doi:
10.1002/jez.2097. [PMID: 29356449] - Youhui Gong, Ting Li, Yucheng Feng, Nannan Liu. The function of two P450s, CYP9M10 and CYP6AA7, in the permethrin resistance of Culex quinquefasciatus.
Scientific reports.
2017 04; 7(1):587. doi:
10.1038/s41598-017-00486-0. [PMID: 28373679] - Kathryn L Anderson, Lindsay C Strowd. Epidemiology, Diagnosis, and Treatment of Scabies in a Dermatology Office.
Journal of the American Board of Family Medicine : JABFM.
2017 01; 30(1):78-84. doi:
10.3122/jabfm.2017.01.160190. [PMID: 28062820] - Geetha A Shetty, Bharathi Hattiangady, Dinesh Upadhya, Adrian Bates, Sahithi Attaluri, Bing Shuai, Maheedhar Kodali, Ashok K Shetty. Chronic Oxidative Stress, Mitochondrial Dysfunction, Nrf2 Activation and Inflammation in the Hippocampus Accompany Heightened Systemic Inflammation and Oxidative Stress in an Animal Model of Gulf War Illness.
Frontiers in molecular neuroscience.
2017; 10(?):182. doi:
10.3389/fnmol.2017.00182. [PMID: 28659758] - Richard E Lizotte, Matthew T Moore. Do Varying Aquatic Plant Species Affect Phytoplankton and Crustacean Responses to a Nitrogen-Permethrin Mixture?.
Bulletin of environmental contamination and toxicology.
2017 Jan; 98(1):58-64. doi:
10.1007/s00128-016-1978-1. [PMID: 27878321] - Pattamaporn Kittayapong, Phanthip Olanratmanee, Pongsri Maskhao, Peter Byass, James Logan, Yesim Tozan, Valérie Louis, Duane J Gubler, Annelies Wilder-Smith. Mitigating Diseases Transmitted by Aedes Mosquitoes: A Cluster-Randomised Trial of Permethrin-Impregnated School Uniforms.
PLoS neglected tropical diseases.
2017 01; 11(1):e0005197. doi:
10.1371/journal.pntd.0005197. [PMID: 28103255]