Methyl 2-aminobenzoate (BioDeep_00000002332)

Secondary id: BioDeep_00000615819, BioDeep_00000862795, BioDeep_00001867647

human metabolite Endogenous

代谢物信息卡片

Methyl ester OF O-aminobenzoic acid

化学式: C8H9NO2 (151.0633254)
中文名称: 邻氨基苯甲酸甲酯
谱图信息: 最多检出来源 Homo sapiens(blood) 1.53%

分子结构信息

SMILES: c1ccc(c(c1)C(=O)OC)N
InChI: InChI=1S/C8H9NO2/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5H,9H2,1H3

描述信息

Methyl 2-aminobenzoate is found in alcoholic beverages. Methyl 2-aminobenzoate is found in essential oils, including bergamot, orange peel, lemon peel, jasmine, ylang-ylang and neroli. Also present in concord grape, strawberry, star fruit, wines, cocoa, black tea and rice bran. Methyl 2-aminobenzoate is a flavouring agent
Found in essential oils, including bergamot, orange peel, lemon peel, jasmine, ylang-ylang and neroliand is also present in concord grape, strawberry, star fruit, wines, cocoa, black tea and rice bran. Flavouring agent.

同义名列表

21 个代谢物同义名

Methyl ester OF O-aminobenzoic acid; O-Aminobenzoic acid methyl ester; 2-Aminobenzoic acid methyl ester; Anthranilic acid methyl ester; O-Aminobenzoate methyl ester; 2-Aminobenzoate methyl ester; Methyl 2-aminobenzoic acid; Methyl O-aminobenzoic acid; 2-(Methoxycarbonyl)aniline; Anthranilate methyl ester; O-Methyl anthranilic acid; Methyl anthranilic acid; O-amino Methyl benzoate; Methyl 2-aminobenzoate; Methyl O-aminobenzoate; O-Methyl anthranilate; O-Carbomethoxyaniline; 2-Carbomethoxyaniline; Carbomethoxyaniline; METHYL ANTHRANILATE; FEMA 2682

数据库引用编号

13 个数据库交叉引用编号

ChEBI: CHEBI:73244
KEGG: C20634
KEGGdrug: D77860
PubChem: 8635
HMDB: HMDB0029703
ChEMBL: CHEMBL1493986
Wikipedia: Methyl_anthranilate
KNApSAcK: C00034600
foodb: FDB000897
chemspider: 13858096
CAS: 134-20-3
PMhub: MS000002366
PubChem: 172232358

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

23 个相关的物种来源信息

54860 Narcissus tazetta: 10.3109/13880209409083015
37334 Citrus maxima: 10.1016/J.PHYTOCHEM.2009.07.031
85571 Citrus reticulata: 10.1016/J.PHYTOCHEM.2009.07.031
558547 Citrus deliciosa: 10.1016/J.PHYTOCHEM.2009.07.031
170989 Citrus hystrix: 10.1016/J.PHYTOCHEM.2009.07.031
264418 Hesperis matronalis: 10.1016/J.PHYTOCHEM.2006.12.009
97307 Prunus padus: 10.1080/10412905.1990.9697889
28974 Averrhoa carambola: 10.1021/JF00062A009
292239 Mentha arvensis: 10.1021/JF00021A034
52820 Acokanthera oblongifolia: 10.1055/S-0028-1099492
660624 Jasminum sambac: 10.1271/BBB.57.1101
54860 Narcissus tazetta: 10.3109/13880209409083015
37334 Citrus maxima: 10.1016/J.PHYTOCHEM.2009.07.031
85571 Citrus reticulata: 10.1016/J.PHYTOCHEM.2009.07.031
558547 Citrus deliciosa: 10.1016/J.PHYTOCHEM.2009.07.031
170989 Citrus hystrix: 10.1016/J.PHYTOCHEM.2009.07.031
264418 Hesperis matronalis: 10.1016/J.PHYTOCHEM.2006.12.009
97307 Prunus padus: 10.1080/10412905.1990.9697889
28974 Averrhoa carambola: 10.1021/JF00062A009
292239 Mentha arvensis: 10.1021/JF00021A034
52820 Acokanthera oblongifolia: 10.1055/S-0028-1099492
660624 Jasminum sambac: 10.1271/BBB.57.1101
9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Vlad Dinu, Pallab Kumar Borah, Molly Muleya, David J Scott, Ryan Lithgo, Jacob Pattem, Stephen E Harding, Gleb E Yakubov, Ian D Fisk. Flavour compounds affect protein structure: The effect of methyl anthranilate on bovine serum albumin conformation. Food chemistry. 2022 Sep; 388(?):133013. doi: 10.1016/j.foodchem.2022.133013. [PMID: 35483284]
Jacob Pollier, Nathan De Geyter, Tessa Moses, Benoît Boachon, José M Franco-Zorrilla, Yuechen Bai, Elia Lacchini, Azra Gholami, Robin Vanden Bossche, Danièle Werck-Reichhart, Sofie Goormachtig, Alain Goossens. The MYB transcription factor Emission of Methyl Anthranilate 1 stimulates emission of methyl anthranilate from Medicago truncatula hairy roots. The Plant journal : for cell and molecular biology. 2019 08; 99(4):637-654. doi: 10.1111/tpj.14347. [PMID: 31009122]
Zi Wei Luo, Jae Sung Cho, Sang Yup Lee. Microbial production of methyl anthranilate, a grape flavor compound. Proceedings of the National Academy of Sciences of the United States of America. 2019 05; 116(22):10749-10756. doi: 10.1073/pnas.1903875116. [PMID: 31085637]
Jeremy Pillet, Alan H Chambers, Christopher Barbey, Zhilong Bao, Anne Plotto, Jinhe Bai, Michael Schwieterman, Timothy Johnson, Benjamin Harrison, Vance M Whitaker, Thomas A Colquhoun, Kevin M Folta. Identification of a methyltransferase catalyzing the final step of methyl anthranilate synthesis in cultivated strawberry. BMC plant biology. 2017 Aug; 17(1):147. doi: 10.1186/s12870-017-1088-1. [PMID: 28859633]
Bonnie J Ohler, Christelle Guédot, Richard S Zack, Peter J Landolt. Aggregation of Thaumatomyia glabra (Diptera: Chloropidae) Males on Iris spp. Flowers Releasing Methyl Anthranilate. Environmental entomology. 2016 12; 45(6):1476-1479. doi: 10.1093/ee/nvw140. [PMID: 28028094]
E J Bernklau, B E Hibbard, A P Norton, L B Bjostad. Methyl Anthranilate as a Repellent for Western Corn Rootworm Larvae (Coleoptera: Chrysomelidae). Journal of economic entomology. 2016 08; 109(4):1683-90. doi: 10.1093/jee/tow090. [PMID: 27122493]
Mariana Martins Gomes Pinheiro, Ana B Miltojević, Niko S Radulović, Ikarastika Rahayu Abdul-Wahab, Fabio Boylan, Patrícia Dias Fernandes. Anti-inflammatory activity of Choisya ternata Kunth essential oil, ternanthranin, and its two synthetic analogs (methyl and propyl N-methylanthranilates). PloS one. 2015; 10(3):e0121063. doi: 10.1371/journal.pone.0121063. [PMID: 25807367]
Alan H Chambers, Shane Alan Evans, Kevin M Folta. Methyl anthranilate and γ-decalactone inhibit strawberry pathogen growth and achene Germination. Journal of agricultural and food chemistry. 2013 Dec; 61(51):12625-33. doi: 10.1021/jf404255a. [PMID: 24328200]
Alexandra Esther, Ralf Tilcher, Jens Jacob. Assessing the effects of three potential chemical repellents to prevent bird damage to corn seeds and seedlings. Pest management science. 2013 Mar; 69(3):425-30. doi: 10.1002/ps.3288. [PMID: 22499556]
Rajinder S Mann, Jared G Ali, Sara L Hermann, Siddharth Tiwari, Kirsten S Pelz-Stelinski, Hans T Alborn, Lukasz L Stelinski. Induced release of a plant-defense volatile 'deceptively' attracts insect vectors to plants infected with a bacterial pathogen. PLoS pathogens. 2012; 8(3):e1002610. doi: 10.1371/journal.ppat.1002610. [PMID: 22457628]
Jiao Yin, Honglin Feng, Hongyan Sun, Jinghui Xi, Yazhong Cao, Kebin Li. Functional analysis of general odorant binding protein 2 from the meadow moth, Loxostege sticticalis L. (Lepidoptera: Pyralidae). PloS one. 2012; 7(3):e33589. doi: 10.1371/journal.pone.0033589. [PMID: 22479417]
David C Robacker, Michelle J Massa, Patrizia Sacchetti, Robert J Bartelt. A novel attractant for Anastrepha ludens (Diptera: Tephritidae) from a Concord grape product. Journal of economic entomology. 2011 Aug; 104(4):1195-203. doi: 10.1603/ec10220. [PMID: 21882683]
Daniela Roell, Thomas W Rösler, Stephanie Degen, Rudolf Matusch, Aria Baniahmad. Antiandrogenic activity of anthranilic acid ester derivatives as novel lead structures to inhibit prostate cancer cell proliferation. Chemical biology & drug design. 2011 Jun; 77(6):450-9. doi: 10.1111/j.1747-0285.2011.01116.x. [PMID: 21439024]
Christy E Manyi-Loh, Roland N Ndip, Anna M Clarke. Volatile compounds in honey: a review on their involvement in aroma, botanical origin determination and potential biomedical activities. International journal of molecular sciences. 2011; 12(12):9514-32. doi: 10.3390/ijms12129514. [PMID: 22272147]
Matthias Erb, Nicolas Foresti, Ted C J Turlings. A tritrophic signal that attracts parasitoids to host-damaged plants withstands disruption by non-host herbivores. BMC plant biology. 2010 Nov; 10(?):247. doi: 10.1186/1471-2229-10-247. [PMID: 21078181]
Tobias G Köllner, Claudia Lenk, Nan Zhao, Irmgard Seidl-Adams, Jonathan Gershenzon, Feng Chen, Jörg Degenhardt. Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine. Plant physiology. 2010 Aug; 153(4):1795-807. doi: 10.1104/pp.110.158360. [PMID: 20519632]
Hayet Edziri, Maha Mastouri, Imed Cheraif, Mahjoub Aouni. Chemical composition and antibacterial, antifungal and antioxidant activities of the flower oil of Retama raetam (Forssk.) Webb from Tunisia. Natural product research. 2010 May; 24(9):789-96. doi: 10.1080/14786410802529190. [PMID: 20461625]
Frank Hippauf, Elke Michalsky, Ruiqi Huang, Robert Preissner, Todd J Barkman, Birgit Piechulla. Enzymatic, expression and structural divergences among carboxyl O-methyltransferases after gene duplication and speciation in Nicotiana. Plant molecular biology. 2010 Feb; 72(3):311-30. doi: 10.1007/s11103-009-9572-0. [PMID: 19936944]
Anna Wajs, Radoslaw Bonikowski, Danuta Kalemba. Different isolation methods for determination of composition of volatiles from Nigella damascena L. seeds. Natural product communications. 2009 Nov; 4(11):1577-80. doi: . [PMID: 19967995]
Jonas M Bengtsson, Yitbarek Wolde-Hawariat, Hamida Khbaish, Merid Negash, Bekele Jembere, Emiru Seyoum, Bill S Hansson, Mattias C Larsson, Ylva Hillbur. Field attractants for Pachnoda interrupta selected by means of GC-EAD and single sensillum screening. Journal of chemical ecology. 2009 Sep; 35(9):1063-76. doi: 10.1007/s10886-009-9684-7. [PMID: 19768509]
Fatima A Jabalpurwala, John M Smoot, Russell L Rouseff. A comparison of citrus blossom volatiles. Phytochemistry. 2009 Jul; 70(11-12):1428-34. doi: 10.1016/j.phytochem.2009.07.031. [PMID: 19747702]
Wipapan Pongcharoen, Vatcharin Rukachaisirikul, Masahiko Isaka, Kanlayanee Sriklung. Cytotoxic metabolites from the wood-decayed fungus Xylaria sp. BCC 9653. Chemical & pharmaceutical bulletin. 2007 Nov; 55(11):1647-8. doi: 10.1248/cpb.55.1647. [PMID: 17978529]
Jihong Wang, Vincenzo De Luca. The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate. The Plant journal : for cell and molecular biology. 2005 Nov; 44(4):606-19. doi: 10.1111/j.1365-313x.2005.02552.x. [PMID: 16262710]
Eugene Sebastian J Nidiry, C S Bujji Babu. Antifungal activity of tuberose absolute and some of its constituents. Phytotherapy research : PTR. 2005 May; 19(5):447-9. doi: 10.1002/ptr.1630. [PMID: 16106389]
David G James. Further field evaluation of synthetic herbivore-induced plant volatiles as attractants for beneficial insects. Journal of chemical ecology. 2005 Mar; 31(3):481-95. doi: 10.1007/s10886-005-2020-y. [PMID: 15898496]
Leslie Hammack, Richard J Petroski. Field capture of northern and western corn rootworm beetles relative to attractant structure and volatility. Journal of chemical ecology. 2004 Sep; 30(9):1809-25. doi: 10.1023/b:joec.0000042403.88930.a7. [PMID: 15586676]
Louise Urruty, Jean-Luc Giraudel, Sovan Lek, Philippe Roudeillac, Michel Montury. Assessment of strawberry aroma through SPME/GC and ANN methods. Classification and discrimination of varieties. Journal of agricultural and food chemistry. 2002 May; 50(11):3129-36. doi: 10.1021/jf0116799. [PMID: 12009974]
Rafael del Campo, Julio J Criado, Eva García, María R Hermosa, A Jiménez-Sánchez, Juan L Manzano, Enrique Monte, E Rodríguez-Fernández, Francisca Sanz. Thiourea derivatives and their nickel(II) and platinum(II) complexes: antifungal activity. Journal of inorganic biochemistry. 2002 Apr; 89(1-2):74-82. doi: 10.1016/s0162-0134(01)00408-1. [PMID: 11931966]
S Moran. Aversion of the feral pigeon and the house sparrow to pellets and sprouts treated with commercial formulations of methyl anthranilate. Pest management science. 2001 Mar; 57(3):248-52. doi: 10.1002/ps.271. [PMID: 11455654]