Glycochenodeoxycholate (BioDeep_00000229659)

Main id: BioDeep_00000001652

Secondary id: BioDeep_00000404224

human metabolite PANOMIX_OTCML-2023 Bile acids BioNovoGene_Lab2019


代谢物信息卡片


Glycochenodeoxycholic acid

化学式: C26H43NO5 (449.3141)
中文名称: 甘氨鹅脱氧胆酸, 甘氨鹅脱氧胆酸钠
谱图信息: 最多检出来源 not specific(not specific) 0%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

Glycochenodeoxycholate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/glycochenodeoxycholate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000229659). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(C(C1(C)4)([H])CCC1([H])C(C(O)3)(C(CC4)([H])C(C)(C([H])2C3)CCC(C2)O)[H])C)CC(=O)NCC(O)=O
InChI: InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1

描述信息

D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
D013501 - Surface-Active Agents > D003902 - Detergents
Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2].

同义名列表

3 个代谢物同义名

Glycochenodeoxycholic acid; Chenodeoxycholylglycine; Glycochenodeoxycholate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AKT1, ANXA5, BCL2, BIRC5, CASP3, CASP8, FABP6, FAS, GNAT3, MAPK3, MCL1, NFKB1, STAT3
Peripheral membrane protein 2 ANXA5, FABP6
Endoplasmic reticulum membrane 2 BCL2, CYP7A1
Nucleus 12 AKT1, BCL2, BIRC5, CASP3, CASP8, FABP6, JUN, MAPK3, MCL1, NFKB1, NR1H4, STAT3
cytosol 12 AKT1, ANXA5, BCL2, BIRC5, CASP3, CASP8, FABP6, FAS, MAPK3, MCL1, NFKB1, STAT3
nuclear body 1 FAS
nucleoplasm 10 AKT1, BIRC5, CASP3, CASP8, JUN, MAPK3, MCL1, NFKB1, NR1H4, STAT3
RNA polymerase II transcription regulator complex 3 JUN, NR1H4, STAT3
Cell membrane 5 AKT1, FAS, SLC10A1, SLCO1B1, SLCO1B3
Cytoplasmic side 1 FABP6
lamellipodium 2 AKT1, CASP8
Multi-pass membrane protein 3 SLC10A1, SLCO1B1, SLCO1B3
cell cortex 1 AKT1
cell surface 1 FAS
glutamatergic synapse 3 AKT1, CASP3, MAPK3
Golgi apparatus 2 FAS, MAPK3
Golgi membrane 1 INS
neuronal cell body 1 CASP3
postsynapse 1 AKT1
sarcolemma 1 ANXA5
acrosomal vesicle 1 GNAT3
plasma membrane 8 AKT1, FAS, GNAT3, MAPK3, SLC10A1, SLCO1B1, SLCO1B3, STAT3
Membrane 9 AKT1, ANXA5, BCL2, FABP6, FAS, MCL1, SLC10A1, SLCO1B1, SLCO1B3
apical plasma membrane 1 GNAT3
basolateral plasma membrane 3 SLC10A1, SLCO1B1, SLCO1B3
caveola 1 MAPK3
extracellular exosome 2 ANXA5, FAS
endoplasmic reticulum 1 BCL2
extracellular space 1 INS
mitochondrion 5 BCL2, CASP8, MAPK3, MCL1, NFKB1
protein-containing complex 5 AKT1, BCL2, BIRC5, CASP8, GNAT3
intracellular membrane-bounded organelle 1 CYP7A1
Microsome membrane 1 CYP7A1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 FAS
Secreted 1 INS
extracellular region 3 ANXA5, INS, NFKB1
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 3 BCL2, CYP7A1, MCL1
mitochondrial outer membrane 3 BCL2, CASP8, MCL1
transcription regulator complex 3 JUN, NFKB1, STAT3
photoreceptor inner segment 1 GNAT3
photoreceptor outer segment 1 GNAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 2 BCL2, MCL1
nuclear membrane 1 BCL2
external side of plasma membrane 2 ANXA5, FAS
microtubule cytoskeleton 2 AKT1, BIRC5
midbody 1 BIRC5
Early endosome 1 MAPK3
cell-cell junction 1 AKT1
vesicle 1 AKT1
Cell projection, lamellipodium 1 CASP8
Membrane raft 1 FAS
pore complex 1 BCL2
Cell junction, focal adhesion 1 MAPK3
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 2 ANXA5, MAPK3
microtubule 1 BIRC5
spindle 2 AKT1, BIRC5
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ANXA5
axoneme 1 GNAT3
interphase microtubule organizing center 1 BIRC5
Late endosome 1 MAPK3
receptor complex 1 NR1H4
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 AKT1
chromatin 4 JUN, NFKB1, NR1H4, STAT3
Chromosome 1 BIRC5
cytoskeleton 2 CASP8, MAPK3
[Isoform 3]: Nucleus 1 NR1H4
centriole 1 BIRC5
nuclear chromosome 2 BIRC5, JUN
Basolateral cell membrane 2 SLCO1B1, SLCO1B3
nuclear envelope 1 MAPK3
endosome lumen 1 INS
Membrane, caveola 1 MAPK3
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
heterotrimeric G-protein complex 1 GNAT3
myosin complex 1 MCL1
Nucleus, nucleoplasm 1 MCL1
Melanosome 1 FAS
euchromatin 2 JUN, NR1H4
cell body 1 CASP8
myelin sheath 1 BCL2
pseudopodium 1 MAPK3
basal plasma membrane 2 SLCO1B1, SLCO1B3
[Isoform 1]: Cytoplasm 1 FABP6
secretory granule lumen 2 INS, NFKB1
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, MAPK3
specific granule lumen 1 NFKB1
kinetochore 1 BIRC5
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
chromosome, centromeric region 1 BIRC5
[Isoform 2]: Cytoplasm 1 FABP6
vesicle membrane 1 ANXA5
chromosome passenger complex 1 BIRC5
[Isoform 2]: Nucleus 1 NR1H4
[Isoform 1]: Nucleus 1 NR1H4
cytoplasmic microtubule 1 BIRC5
Basal cell membrane 2 SLCO1B1, SLCO1B3
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
CD95 death-inducing signaling complex 2 CASP8, FAS
death-inducing signaling complex 3 CASP3, CASP8, FAS
ripoptosome 1 CASP8
[Isoform 1]: Cell membrane 1 FAS
[Isoform 4]: Nucleus 1 NR1H4
transcription factor AP-1 complex 1 JUN
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 1 NFKB1
NF-kappaB p50/p65 complex 1 NFKB1
glycogen granule 1 FAS


文献列表

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