Vitamin P (BioDeep_00001876165)

代谢物信息卡片

Quercetin 3-O-rutinoside

化学式: C27H30O16 (610.1534)
中文名称: 槲皮素3-O-芸香糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
InChI: InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3

描述信息

同义名列表

2 个代谢物同义名

Quercetin 3-O-rutinoside; Vitamin P

数据库引用编号

6 个数据库交叉引用编号

ChEBI: CHEBI:91643
PubChem: 5293655
ChEMBL: CHEMBL32579
CAS: 1558680-22-0
CAS: 949926-49-2
CAS: 10163-13-0

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

177 个相关的物种来源信息

138511 - Acacia aulacocarpa: 10.1021/NP990482W
1173637 - Acacia cambagei: 10.1021/NP990482W
1120459 - Acacia kempeana: 10.1021/NP990482W
139014 - Acacia paradoxa: 10.1021/NP990482W
282722 - Achillea biebersteinii: 10.1248/CPB.52.1462
282730 - Achillea collina: 10.1248/CPB.52.1462
282734 - Achillea erba-rotta: 10.1248/CPB.52.1462
13329 - Achillea millefolium: 10.1248/CPB.52.1462
282752 - Achillea nana: 10.1248/CPB.52.1462
462376 - Acrisione denticulata: 10.1021/NP50051A034
199616 - Aframomum daniellii: 10.1248/CPB.56.97
647088 - Albizia myriophylla: 10.1021/NP020220L
47037 - Alhagi maurorum: 10.1007/S10600-009-9287-0
72332 - Artemisia absinthium: 10.1007/BF00595086
1227615 - Artemisia alba: 10.1007/BF00595086
35608 - Artemisia annua: 10.1007/BF00595086
262982 - Artemisia apiacea: 10.1007/BF00595086
265783 - Artemisia capillaris: 10.1007/BF00595086
496566 - Artemisia carvifolia: 10.1007/BF00595086
401898 - Artemisia gmelinii: 10.1007/BF00595086
265784 - Artemisia iwayomogi: 10.1007/BF00595086
72351 - Artemisia scoparia: 10.1007/BF00595086
1903237 - Artemisia vachanica: 10.1007/BF00595086
155124 - Aspalathus linearis: 10.1248/BPB.29.1271
1120561 - Asparagus gonoclados: 10.1016/S0031-9422(00)98555-8
5061 - Aspergillus niger: 10.1021/JF102871G
669631 - Aster alpinus: 10.1007/BF02787086
314325 - Aster sedifolius: 10.1007/BF02787086
20410 - Astragalus cicer: 10.1007/BF00602480
72900 - Baccharis dracunculifolia: 10.1248/CPB.51.197
1654445 - Baccharis neaei: 10.1248/CPB.51.197
41488 - Baccharis neglecta: 10.1248/CPB.51.197
1654448 - Baccharis sagittalis: 10.1248/CPB.51.197
2707840 - Baccharis truncata: 10.1248/CPB.51.197
216991 - Betula humilis: 10.1002/ARDP.19532861002
78630 - Betula platyphylla: 10.1016/S0031-9422(00)86815-6
1527830 - Bidens parviflora: 10.3390/MOLECULES13081931
83906 - Boehmeria nivea: 10.1016/0031-9422(75)80399-2
52451 - Bupleurum chinense: 10.1007/BF00576107
53846 - Caesalpinia pulcherrima: 10.1021/NP0201523
1407748 - Camellia crassicolumna: 10.1021/JF802974M
4442 - Camellia sinensis: 10.1021/NP0580614
403832 - Caragana sinica: 10.3390/MOLECULES15106722
53851 - Cassia: 10.1021/NP980195C
121072 - Cassytha: 10.1021/NP070564H
489979 - Celastrus hindsii: 10.1021/JF052743F
3559 - Chenopodium album: 10.1021/JF800421J
128608 - Cinnamomum verum: 10.1021/JF052736R
43365 - Clitoria: 10.1016/S0031-9422(02)00486-7
2907091 - Cnidoscolus texanus: 10.1055/S-2007-990226
461574 - Cocculus diversifolius: 10.1021/NP050082A
106663 - Colubrina: 10.1021/NP000225N
72917 - Conyza canadensis: 10.1021/NP000442O
510735 - Crataegus pinnatifida: 10.1021/JF903337F
323037 - Croton caudatus: 10.3390/MOLECULES15031097
3662 - Cucurbita moschata: 10.1021/NP068074X
155289 - Dodecadenia grandiflora: 10.1016/J.FITOTE.2010.01.011
1341708 - Embelia parviflora: 10.1016/J.PHYTOCHEM.2006.07.025
2595069 - Embelia schimperi: 10.1016/J.PHYTOCHEM.2006.07.025
2026872 - Eria mucronata:
985411 - Erica glauca: 10.1007/BF00568605
72917 - Erigeron canadensis: 10.1021/NP000442O
1130977 - Eucalyptus cypellocarpa: 10.1021/NP0001981
38843 - Euphorbia amygdaloides: 10.1016/J.PHYTOCHEM.2006.06.030
1333909 - Euphorbia ferganensis: 10.1016/J.PHYTOCHEM.2006.06.030
458693 - Euphorbia formosana: 10.1016/J.PHYTOCHEM.2006.06.030
318062 - Euphorbia hirta: 10.1016/J.PHYTOCHEM.2006.06.030
212301 - Euphorbia humifusa: 10.1016/J.PHYTOCHEM.2006.06.030
457253 - Euphorbia jolkinii: 10.1016/J.PHYTOCHEM.2006.06.030
212941 - Euphorbia myrsinites: 10.1016/J.PHYTOCHEM.2006.06.030
1087772 - Euphorbia nicaeensis: 10.1016/J.PHYTOCHEM.2006.06.030
492572 - Euphorbia palustris: 10.1016/J.PHYTOCHEM.2006.06.030
756628 - Euphorbia pannonica: 10.1016/J.PHYTOCHEM.2006.06.030
273621 - Euphorbia pekinensis: 10.1016/J.PHYTOCHEM.2006.06.030
1087776 - Euphorbia pithyusa: 10.1016/J.PHYTOCHEM.2006.06.030
3617 - Fagopyrum esculentum:
3494 - Ficus carica:
463862 - Ficus nervosa:
66386 - Ficus pumila:
479338 - Ficus ruficaulis:
56033 - Fraxinus chinensis: 10.1016/S0031-9422(97)00790-5
2291128 - Fraxinus stylosa: 10.1016/S0031-9422(97)00790-5
114476 - Gardenia jasminoides: 10.1021/NP0580816
3310 - Ginkgo: 10.1016/S0031-9422(01)00320-X
3311 - Ginkgo biloba: 10.1021/JF011682S
74614 - Glycyrrhiza inflata: 10.1248/CPB.51.1338
74613 - Glycyrrhiza uralensis: 10.1248/CPB.51.1338
182084 - Gynostemma pentaphyllum: 10.1021/NP0600898
1000428 - Hedlundia mougeotii: 10.1007/BF00565361
261776 - Helichrysum arenarium: 10.1248/CPB.57.853
3486 - Humulus lupulus: 10.1021/JF1049084
210378 - Hypericum ascyron: 10.1248/CPB.56.1164
268978 - Hypericum balearicum: 10.1248/CPB.56.1164
1136967 - Hypericum curvisepalum: 10.1248/CPB.56.1164
1043417 - Hypericum elodeoides: 10.1248/CPB.56.1164
2306224 - Hypericum faberi: 10.1248/CPB.56.1164
212239 - Hypericum patulum: 10.1248/CPB.56.1164
1341051 - Hypericum polyanthemum: 10.1248/CPB.56.1164
673932 - Hypericum reflexum: 10.1248/CPB.56.1164
282558 - Hypericum triquetrifolium: 10.1248/CPB.56.1164
1321360 - Hypericum wightianum: 10.1248/CPB.56.1164
53199 - Ilex brevicuspis: 10.1248/CPB.55.422
1043419 - Ilex chinensis: 10.1248/CPB.55.422
185544 - Ilex purpurea: 10.1248/CPB.55.422
486091 - Inga velutina: 10.1016/S0031-9422(00)94288-2
595360 - Jacobaea ambracea: 10.1021/NP50051A034
75953 - Lactuca indica: 10.1039/J39690001096
75943 - Lactuca serriola:
422332 - Lasiocephalus ovatus: 10.1021/NP50051A034
99072 - Leucanthemum vulgare: 10.1007/BF00636588
105884 - Lonicera japonica: 10.1248/CPB.55.1073
34305 - Lotus japonicus: 10.1246/NIKKASHI1948.70.36
1524233 - Melilotus neapolitanus: 10.3390/12020263
28525 - Menyanthes trifoliata: 10.1039/C19680001277
43522 - Morinda citrifolia: 10.1021/JF010492E
659048 - Morinda morindoides: 10.1021/NP068065O
85232 - Morus nigra: 10.1021/JF703709R
327208 - Neocussonia bojeri: 10.1016/S0031-9422(02)00263-7
1297881 - Neocussonia longipedicellata: 10.1016/S0031-9422(02)00263-7
63479 - Nerium oleander: 10.1002/ARDP.19562891103
4087 - Nicotiana alata: 10.1021/JF1017737
254027 - Oldenlandia diffusa: 10.1007/S11418-007-0212-1
4146 - Olea europaea:
34220 - Packera glabella: 10.1021/NP50051A034
321567 - Peltophorum africanum: 10.1016/S0031-9422(00)80675-5
49563 - Peucedanum japonicum: 10.1021/JF0262458
296036 - Phyllanthus emblica: 10.1055/S-2007-969635
296034 - Phyllanthus niruri: 10.1248/CPB.50.841
296035 - Phyllanthus urinaria:
161495 - Physalis longifolia:
1427529 - Piper regnellii: 10.1016/J.PHYTOCHEM.2008.02.018
98712 - Pittocaulon praecox: 10.1021/NP50051A034
120625 - Podocarpus nivalis: 10.1248/CPB.56.585
120631 - Podocarpus salignus: 10.1248/CPB.56.585
57926 - Potentilla anserina: 10.1080/10286020.2010.489826
1958861 - Pourouma cecropiifolia: 10.1021/JF9041497
102107 - Prunus mume: 10.1021/NP020058M
22662 - Punica: 10.1016/J.JEP.2006.09.006
3609 - Rhamnus: 10.1016/S0031-9422(99)00262-9
666566 - Rhodiola semenovii:
74645 - Rosa rugosa:
267261 - Rosa villosa:
1786032 - Rumex chalepensis:
174651 - Rumex japonicus: 10.1007/BF00636016
933122 - Salvia blepharophylla: 10.1002/CBDV.200690093
1520014 - Salvia broussonetii: 10.1002/CBDV.200690093
207754 - Salvia dorrii: 10.1002/CBDV.200690093
268908 - Salvia greggii: 10.1002/CBDV.200690093
49212 - Salvia hispanica: 10.1002/CBDV.200690093
392673 - Salvia munzii: 10.1002/CBDV.200690093
268922 - Salvia polystachya: 10.1002/CBDV.200690093
933147 - Salvia sessei: 10.1002/CBDV.200690093
2039553 - Salvia xalapensis: 10.1002/CBDV.200690093
2726419 - Sedum litoreum: 10.1007/BF00567817
91146 - Sedum sarmentosum: 10.1007/BF00567817
2841764 - Senecio adenophyllus: 10.1021/NP50051A034
189242 - Senecio nemorensis: 10.1021/NP50051A034
1892290 - Senecio polyodon: 10.1021/NP50051A034
1892294 - Senecio sandersonii: 10.1021/NP50051A034
85882 - Senecio viscosus: 10.1021/NP50051A034
346403 - Senna multijuga: 10.1021/NP900644X
210324 - Sida cordata: 10.1002/CHIN.200846211
152363 - Sinomenium acutum: 10.1021/NP050082A
4113 - Solanum tuberosum:
330182 - Solidago flexicaulis: 10.1248/CPB.55.815
72976 - Solidago petiolaris: 10.1248/CPB.55.815
462879 - Solidago virgaurea: 10.1248/CPB.55.815
49840 - Sophora flavescens: 10.1021/NP010081S
99302 - Strychnos spinosa: 10.1016/S0031-9422(00)85534-X
1040936 - Strychnos tricalysioides: 10.1016/S0031-9422(00)85534-X
167719 - Stylosanthes erecta: 10.1021/NP0700671
479933 - Tephroseris subdentata: 10.1021/NP50051A034
43575 - Uncaria rhynchophylla:
203102 - Veratrum stenophyllum: 10.1016/0031-9422(77)84048-X
3916 - Vigna radiata var. radiata: 10.1007/BF00598601
199627 - Wurfbainia villosa: 10.1248/CPB.56.97
345809 - Ziziphus lotus: 10.1016/S0031-9422(99)00262-9

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	7	ADIG, AKT1, ALB, CASP3, CAT, MEFV, SH2D1A
Peripheral membrane protein	2	ACHE, CYP1B1
Endoplasmic reticulum membrane	2	CD4, CYP1B1
Cytoplasmic vesicle, autophagosome	1	MEFV
Nucleus	7	ACHE, ADIG, AKT1, ALB, CASP3, GABPA, MEFV
autophagosome	1	MEFV
cytosol	8	AKT1, ALB, CASP3, CAT, GPT, GSR, MEFV, SH2D1A
centrosome	1	ALB
nucleoplasm	4	AKT1, CASP3, GABPA, MEFV
Cell membrane	6	ACHE, AKT1, CD4, CMKLR1, MGAM, TNF
lamellipodium	2	AKT1, MEFV
Multi-pass membrane protein	1	CMKLR1
Synapse	1	ACHE
cell cortex	1	AKT1
cell surface	2	ACHE, TNF
glutamatergic synapse	2	AKT1, CASP3
Golgi apparatus	2	ACHE, ALB
neuromuscular junction	1	ACHE
neuronal cell body	2	CASP3, TNF
postsynapse	1	AKT1
plasma membrane	6	ACHE, AKT1, CD4, CMKLR1, MGAM, TNF
Membrane	7	ACHE, ADIG, AKT1, CAT, CMKLR1, CYP1B1, MGAM
apical plasma membrane	1	MGAM
extracellular exosome	5	ALB, CAT, GPT, GSR, MGAM
endoplasmic reticulum	1	ALB
extracellular space	7	ACHE, ALB, CXCL8, IL6, PNLIP, RARRES2, TNF
perinuclear region of cytoplasm	1	ACHE
mitochondrion	3	CAT, CYP1B1, GSR
protein-containing complex	3	AKT1, ALB, CAT
intracellular membrane-bounded organelle	2	CAT, CYP1B1
Microsome membrane	1	CYP1B1
postsynaptic density	1	CASP3
Single-pass type I membrane protein	1	CD4
Secreted	8	ACHE, ADIG, ALB, CXCL8, IL6, MGAM, PNLIP, RARRES2
extracellular region	10	ACHE, ADIG, ALB, CAT, CXCL8, IL6, MGAM, PNLIP, RARRES2, TNF
Single-pass membrane protein	2	ADIG, MGAM
mitochondrial matrix	2	CAT, GSR
Extracellular side	1	ACHE
anchoring junction	1	ALB
external side of plasma membrane	3	CD4, GSR, TNF
cytoplasmic vesicle	1	MEFV
microtubule cytoskeleton	1	AKT1
Early endosome	1	CD4
cell-cell junction	1	AKT1
recycling endosome	1	TNF
Single-pass type II membrane protein	1	TNF
vesicle	1	AKT1
Cell projection, lamellipodium	1	MEFV
Membrane raft	2	CD4, TNF
focal adhesion	1	CAT
microtubule	1	MEFV
spindle	1	AKT1
extracellular matrix	1	RARRES2
Peroxisome	1	CAT
basement membrane	1	ACHE
Peroxisome matrix	1	CAT
peroxisomal matrix	1	CAT
peroxisomal membrane	1	CAT
Mitochondrion intermembrane space	1	AKT1
mitochondrial intermembrane space	1	AKT1
collagen-containing extracellular matrix	1	RARRES2
Cell projection, ruffle	1	MEFV
ruffle	1	MEFV
ciliary basal body	2	AKT1, ALB
chromatin	1	GABPA
microtubule associated complex	1	MEFV
phagocytic cup	1	TNF
centriole	1	ALB
spindle pole	1	ALB
blood microparticle	1	ALB
Lipid-anchor, GPI-anchor	1	ACHE
Lipid droplet	1	ADIG
tertiary granule membrane	1	MGAM
side of membrane	1	ACHE
ficolin-1-rich granule lumen	1	CAT
secretory granule lumen	1	CAT
endoplasmic reticulum lumen	3	ALB, CD4, IL6
platelet alpha granule lumen	1	ALB
clathrin-coated endocytic vesicle membrane	1	CD4
[Isoform 2]: Nucleus	1	MEFV
synaptic cleft	1	ACHE
ficolin-1-rich granule membrane	1	MGAM
death-inducing signaling complex	1	CASP3
[Isoform 1]: Cytoplasm, cytoskeleton	1	MEFV
canonical inflammasome complex	1	MEFV
[Tumor necrosis factor, soluble form]: Secreted	1	TNF
T cell receptor complex	1	CD4
platelet dense granule lumen	1	RARRES2
catalase complex	1	CAT
interleukin-6 receptor complex	1	IL6
[Isoform H]: Cell membrane	1	ACHE
ciliary transition fiber	1	ALB
[C-domain 2]: Secreted	1	TNF
[Tumor necrosis factor, membrane form]: Membrane	1	TNF
[C-domain 1]: Secreted	1	TNF

文献列表

Daniel Lotanna Ajaghaku, Peter Achunike Akah, Emmanuel Emeka Ilodigwe, Sunday Odunke Nduka, Uduma Eke Osonwa, Festus Basden Chinedu Okoye. Upregulation of CD4+ T-Lymphocytes by Isomeric Mixture of Quercetin-3-O-Rutinoside and Quercetin-3-O-Robinobioside Isolated from Millettia aboensis. Immunological investigations. 2018 May; 47(4):372-388. doi: 10.1080/08820139.2018.1433201. [PMID: 29405788]
Li-Li Dou, Li Duan, Long Guo, Le-Le Liu, Yu-Dong Zhang, Ping Li, E-Hu Liu. An UHPLC-MS/MS method for simultaneous determination of quercetin 3-O-rutinoside, kaempferol 3-O-rutinoside, isorhamnetin 3-O-rutinoside, bilobalide and ligustrazine in rat plasma, and its application to pharmacokinetic study of Xingxiong injection. Chinese journal of natural medicines. 2017 Sep; 15(9):710-720. doi: 10.1016/s1875-5364(17)30101-2. [PMID: 28991533]
Rahmat Ali Khan, Muhammad Rashid Khan, Sumaira Sahreen, Mushtaq Ahmed. Evaluation of phenolic contents and antioxidant activity of various solvent extracts of Sonchus asper (L.) Hill. Chemistry Central journal. 2012 Feb; 6(1):12. doi: 10.1186/1752-153x-6-12. [PMID: 22305477]
Pavle Mašković, Slavica Solujić, Vladimir Mihailović, Milan Mladenović, Milica Cvijović, Jelena Mladenović, Gordana Aćamović-Đoković, Vladimir Kurćubić. Phenolic compounds and biological activity of Kitaibelia vitifolia. Journal of medicinal food. 2011 Dec; 14(12):1617-23. doi: 10.1089/jmf.2011.0013. [PMID: 21877950]
Sara Sjöström, Ulf Hjalmars, Per Juto, Göran Wadell, Göran Hallmans, Anne Tjönneland, Jytte Halkjaer, Jonas Manjer, Martin Almquist, Beatrice S Melin. Human immunoglobulin G levels of viruses and associated glioma risk. Cancer causes & control : CCC. 2011 Sep; 22(9):1259-66. doi: 10.1007/s10552-011-9799-3. [PMID: 21717196]
Min Zhang, Yong Meng, Yongli Yang, Yancai Liu, Caiqin Dong, Jianming Xiao, Ling Zhao, Fang Li. Major inducing factors of hypertensive complications and the interventions required to reduce their prevalence: an epidemiological study of hypertension in a rural population in China. BMC public health. 2011 May; 11(?):301. doi: 10.1186/1471-2458-11-301. [PMID: 21569365]
Showkat Ahmad Ganie, Ehtishamul Haq, Abid Hamid, Yasrib Qurishi, Zahid Mahmood, Bilal Ahmad Zargar, Akbar Masood, Mohmmad Afzal Zargar. Carbon tetrachloride induced kidney and lung tissue damages and antioxidant activities of the aqueous rhizome extract of Podophyllum hexandrum. BMC complementary and alternative medicine. 2011 Feb; 11(?):17. doi: 10.1186/1472-6882-11-17. [PMID: 21356055]
T V Thu, Teck Chwen Loh, H L Foo, H Yaakub, M H Bejo. Effects of liquid metabolite combinations produced by Lactobacillus plantarum on growth performance, faeces characteristics, intestinal morphology and diarrhoea incidence in postweaning piglets. Tropical animal health and production. 2011 Jan; 43(1):69-75. doi: 10.1007/s11250-010-9655-6. [PMID: 20632092]
Chunhua Zhou, Chongde Sun, Kunsong Chen, Xian Li. Flavonoids, phenolics, and antioxidant capacity in the flower of Eriobotrya japonica Lindl. International journal of molecular sciences. 2011; 12(5):2935-45. doi: 10.3390/ijms12052935. [PMID: 21686159]
O U Amaeze, G A Ayoola, M O Sofidiya, A A Adepoju-Bello, A O Adegoke, H A B Coker. Evaluation of antioxidant activity of Tetracarpidium conophorum (Müll. Arg) Hutch & Dalziel leaves. Oxidative medicine and cellular longevity. 2011; 2011(?):976701. doi: 10.1155/2011/976701. [PMID: 21912723]
John L Freeman, Masanori Tamaoki, Cecil Stushnoff, Colin F Quinn, Jennifer J Cappa, Jean Devonshire, Sirine C Fakra, Matthew A Marcus, Steve P McGrath, Doug Van Hoewyk, Elizabeth A H Pilon-Smits. Molecular mechanisms of selenium tolerance and hyperaccumulation in Stanleya pinnata. Plant physiology. 2010 Aug; 153(4):1630-52. doi: 10.1104/pp.110.156570. [PMID: 20498337]
Tom P V M de Jong, Rafal Chrzan, Aart J Klijn, Pieter Dik. Treatment of the neurogenic bladder in spina bifida. Pediatric nephrology (Berlin, Germany). 2008 Jun; 23(6):889-96. doi: 10.1007/s00467-008-0780-7. [PMID: 18350321]
Ioannis P Tzanakis, Antonia N Papadaki, Mingxin Wei, Stella Kagia, Vlassios V Spadidakis, Nikolaos E Kallivretakis, Dimitrios G Oreopoulos. Magnesium carbonate for phosphate control in patients on hemodialysis. A randomized controlled trial. International urology and nephrology. 2008; 40(1):193-201. doi: 10.1007/s11255-007-9300-0. [PMID: 18193489]
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