SAICAR (BioDeep_00001868455)
Main id: BioDeep_00000005666
代谢物信息卡片
化学式: C13H19N4O12P (454.0737)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C([C@@H](C(=O)O)NC(=O)c1c(N)n(cn1)[C@H]1[C@@H]([C@@H]([C@@H](COP(=O)(O)O)O1)O)O)C(=O)O
InChI: InChI=1S/C13H19N4O12P/c14-10-7(11(22)16-4(13(23)24)1-6(18)19)15-3-17(10)12-9(21)8(20)5(29-12)2-28-30(25,26)27/h3-5,8-9,12,20-21H,1-2,14H2,(H,16,22)(H,18,19)(H,23,24)(H2,25,26,27)/t4-,5+,8+,9+,12+/m0/s1
描述信息
A 1-(phosphoribosyl)imidazolecarboxamide resulting from the formal condesation of the darboxy group of 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid with the amino group of L-aspartic acid.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:18319
- KEGG: C04823
- PubChem: 160666
- CAS: 3031-95-6
- MetaboLights: MTBLC18319
- PubChem: 7384
- PDB-CCD: OK8
- 3DMET: B04963
- NIKKAJI: J7.666J
- RefMet: SAICAR
- KNApSAcK: 18319
分类词条
相关代谢途径
Reactome(0)
BioCyc(3)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 4896 - Schizosaccharomyces pombe: 10.1039/C4MB00346B
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Péter Monostori, Glynis Klinke, Jana Hauke, Sylvia Richter, Jörgen Bierau, Sven F Garbade, Georg F Hoffmann, Claus-Dieter Langhans, Dorothea Haas, Jürgen G Okun. Extended diagnosis of purine and pyrimidine disorders from urine: LC MS/MS assay development and clinical validation.
PloS one.
2019; 14(2):e0212458. doi:
10.1371/journal.pone.0212458. [PMID: 30817767] - M Henneke, S Dreha-Kulaczewski, K Brockmann, M van der Graaf, M A A P Willemsen, U Engelke, P Dechent, A Heerschap, G Helms, R A Wevers, J Gärtner. In vivo proton MR spectroscopy findings specific for adenylosuccinate lyase deficiency.
NMR in biomedicine.
2010 Jun; 23(5):441-5. doi:
10.1002/nbm.1480. [PMID: 20175147] - Cyril Gitiaux, Irène Ceballos-Picot, Sandrine Marie, Vassili Valayannopoulos, Marlène Rio, Séverine Verrieres, Jean François Benoist, Marie Françoise Vincent, Isabelle Desguerre, Nadia Bahi-Buisson. Misleading behavioural phenotype with adenylosuccinate lyase deficiency.
European journal of human genetics : EJHG.
2009 Jan; 17(1):133-6. doi:
10.1038/ejhg.2008.174. [PMID: 18830228] - A M Marinaki, M Champion, M A Kurian, H A Simmonds, S Marie, M F Vincent, G van den Berghe, J A Duley, L D Fairbanks. Adenylosuccinate lyase deficiency--first British case.
Nucleosides, nucleotides & nucleic acids.
2004 Oct; 23(8-9):1231-3. doi:
10.1081/ncn-200027494. [PMID: 15571235] - F A van den Bergh, A N Bosschaart, G Hageman, M Duran, B Tien Poll-The. Adenylosuccinase deficiency with neonatal onset severe epileptic seizures and sudden death.
Neuropediatrics.
1998 Feb; 29(1):51-3. doi:
10.1055/s-2007-973536. [PMID: 9553952] - J Krijt, I Sebesta, A Svehlakova, A Zumrova, J Zeman. Adenylosuccinate lyase deficiency in a Czech girl and two siblings.
Advances in experimental medicine and biology.
1994; 370(?):367-70. doi:
10.1007/978-1-4615-2584-4_79. [PMID: 7660930] - C Salerno, C Crifò, E Capuozzo, O Giardini. Anomalous response to intravenous fructose tolerance test in a case of deficit of adenylosuccinate lyase.
Advances in experimental medicine and biology.
1994; 370(?):371-4. doi:
10.1007/978-1-4615-2584-4_80. [PMID: 7660931] - P K Laikind, J E Seegmiller, H E Gruber. Detection of 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole in urine by use of the Bratton-Marshall reaction: identification of patients deficient in adenylosuccinate lyase activity.
Analytical biochemistry.
1986 Jul; 156(1):81-90. doi:
10.1016/0003-2697(86)90158-2. [PMID: 3740420]
