Isoflurophate (BioDeep_00001867949)
Main id: BioDeep_00000004395
代谢物信息卡片
diisopropyl fluorophosphate
化学式: C6H14FO3P (184.0665)
中文名称: 3-氟-4-甲氧基苯乙酮, 氟磷酸二异丙酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)OP(=O)(F)OC(C)C
InChI: InChI=1S/C6H14FO3P/c1-5(2)9-11(7,8)10-6(3)4/h5-6H,1-4H3
描述信息
S - Sensory organs > S01 - Ophthalmologicals > S01E - Antiglaucoma preparations and miotics > S01EB - Parasympathomimetics
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:17941
- KEGG: C00202
- KEGGdrug: D00043
- PubChem: 5936
- DrugBank: DB00677
- ChEMBL: CHEMBL1025
- MeSH: Isoflurophate
- CAS: 55-91-4
- PubChem: 3502
- 3DMET: B00057
- NIKKAJI: J4.564K
- RefMet: Isoflurophate
- KNApSAcK: 17941
分类词条
相关代谢途径
Reactome(0)
BioCyc(7)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lambert K Sørensen, Jørgen B Hasselstrøm, Jesper D Gunst, Ole S Søgaard, Mads Kjolby. Determination of camostat and its metabolites in human plasma - Preservation of samples and quantification by a validated UHPLC-MS/MS method.
Clinical biochemistry.
2021 Oct; 96(?):56-62. doi:
10.1016/j.clinbiochem.2021.07.007. [PMID: 34252447] - Royce H Nichols, Janice E Chambers. Reactivation of organophosphate-inhibited serum butyrylcholinesterase by novel substituted phenoxyalkyl pyridinium oximes and traditional oximes.
Toxicology.
2021 03; 452(?):152719. doi:
10.1016/j.tox.2021.152719. [PMID: 33592259] - Marson Putra, Meghan Gage, Shaunik Sharma, Cara Gardner, Grace Gasser, Vellareddy Anantharam, Thimmasettappa Thippeswamy. Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model.
Annals of the New York Academy of Sciences.
2020 11; 1479(1):75-93. doi:
10.1111/nyas.14314. [PMID: 32037612] - Marson Putra, Shaunik Sharma, Meghan Gage, Grace Gasser, Andy Hinojo-Perez, Ashley Olson, Adriana Gregory-Flores, Sreekanth Puttachary, Chong Wang, Vellareddy Anantharam, Thimmasettappa Thippeswamy. Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model.
Neurobiology of disease.
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Molecular pharmacology.
2019 11; 96(5):629-640. doi:
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Toxicology and applied pharmacology.
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Chemical research in toxicology.
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Life sciences.
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2012 Feb; 195(3):189-98. doi:
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2011 Mar; 57(3):211-6. doi:
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Oxidative medicine and cellular longevity.
2011; 2011(?):213686. doi:
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Analytical and bioanalytical chemistry.
2010 Nov; 398(6):2677-91. doi:
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Chemico-biological interactions.
2010 Sep; 187(1-3):191-8. doi:
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Chemico-biological interactions.
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Drug metabolism and disposition: the biological fate of chemicals.
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2010 Jan; 173(1-3):40-6. doi:
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2009 Nov; 10(?):28. doi:
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2009 Oct; 240(2):124-31. doi:
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2009 May; 39(5):407-14. doi:
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