ALLYL ALCOHOL (BioDeep_00001867719)

Main id: BioDeep_00000004818

 

PANOMIX_OTCML-2023


代谢物信息卡片


ALLYL ALCOHOL

化学式: C3H6O (58.041862599999995)
中文名称: 烯丙醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CCO
InChI: InChI=1S/C3H6O/c1-2-3-4/h2,4H,1,3H2

描述信息

A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.

同义名列表

1 个代谢物同义名

ALLYL ALCOHOL



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Jiajin Xia, Baolong Zhu, Qiuling Wan, Yinghua Yu, Shenlin Huang, Jian Zhang, Xueliang Huang. Gold-Catalyzed Cascade Reaction of Diynamides with Allylic Alcohols: A Versatile Platform to Allenamide, 2-Aminofuran and Bridged [2.2.2]Octadiene Derivatives. Chemistry (Weinheim an der Bergstrasse, Germany). 2023 Jun; 29(33):e202300826. doi: 10.1002/chem.202300826. [PMID: 36973187]
  • Hak Joong Kim, Keishi Ishida, Mie Ishida-Ito, Christian Hertweck. Sequential Allylic Alcohol Formation by a Multifunctional Cytochrome P450 Monooxygenase with Rare Redox Partners. Angewandte Chemie (International ed. in English). 2022 06; 61(26):e202203264. doi: 10.1002/anie.202203264. [PMID: 35416382]
  • Edward J Whittle, Yuanheng Cai, Jantana Keereetaweep, Jin Chai, Peter H Buist, John Shanklin. Castor Stearoyl-ACP Desaturase Can Synthesize a Vicinal Diol by Dioxygenase Chemistry. Plant physiology. 2020 02; 182(2):730-738. doi: 10.1104/pp.19.01111. [PMID: 31806737]
  • Erica E Carroll, Danielle L Ippolito, Matthew G Permenter, B Claire McDyre, Christine E Baer, David M Kumsher, Molly H Boyle, Valerie T DiVito, John A Lewis, Jason M Koontz. Utility of Serum miR-122, Liver Enzymes, and Hepatic Histopathology in Response to Hepatotoxicants in Sprague-Dawley Rats. Toxicologic pathology. 2018 10; 46(7):835-846. doi: 10.1177/0192623318795435. [PMID: 30205766]
  • Jia Liu, Honglian Li, Chao Zheng, Shichao Lu, Xianru Guo, Xinming Yin, Risong Na, Bin Yu, Min Wang. A General Asymmetric Synthesis of (R)-Matsutakeol and Flavored Analogs. Molecules (Basel, Switzerland). 2017 Feb; 22(3):. doi: 10.3390/molecules22030364. [PMID: 28264452]
  • Louise E Smith, Christian Bryant, Marta Krasowska, Allison J Cowin, Jason D Whittle, Sheila MacNeil, Robert D Short. Haptotatic Plasma Polymerized Surfaces for Rapid Tissue Regeneration and Wound Healing. ACS applied materials & interfaces. 2016 Dec; 8(48):32675-32687. doi: 10.1021/acsami.6b11320. [PMID: 27934156]
  • Danielle L Ippolito, Mohamed Diwan M AbdulHameed, Gregory J Tawa, Christine E Baer, Matthew G Permenter, Bonna C McDyre, William E Dennis, Molly H Boyle, Cheryl A Hobbs, Michael A Streicker, Bobbi S Snowden, John A Lewis, Anders Wallqvist, Jonathan D Stallings. Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. Toxicological sciences : an official journal of the Society of Toxicology. 2016 Jan; 149(1):67-88. doi: 10.1093/toxsci/kfv214. [PMID: 26396155]
  • Yoko Nishimura, Yuji Morikawa, Chiaki Kondo, Yutaka Tonomura, Ryou Fukushima, Mikinori Torii, Takeki Uehara. Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies. Journal of applied toxicology : JAT. 2013 Oct; 33(10):1120-30. doi: 10.1002/jat.2867. [PMID: 23558518]
  • Sofie Starckx, Ameesha Batheja, Geert R Verheyen, Sandra De Jonghe, Kristel Steemans, Bram Van Dijck, Monica Singer, Nancy Bogdan, Jan Snoeys, Petra Vinken, Jennifer C Sasaki, Jacky Van Gompel, Peggy Guzzie-Peck, Ann Lampo, Lieve Lammens. Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats. Toxicologic pathology. 2013 Jul; 41(5):795-804. doi: 10.1177/0192623312464436. [PMID: 23143187]
  • Juan E Puche, Youngmin A Lee, Jingjing Jiao, Costica Aloman, Maria I Fiel, Ursula Muñoz, Thomas Kraus, Tingfang Lee, Hal F Yee, Scott L Friedman. A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice. Hepatology (Baltimore, Md.). 2013 Jan; 57(1):339-50. doi: 10.1002/hep.26053. [PMID: 22961591]
  • Victoria Kearns, Anita Mistry, Sharon Mason, Yamini Krishna, Carl Sheridan, Robert Short, Rachel L Williams. Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration. Journal of materials science. Materials in medicine. 2012 Aug; 23(8):2013-21. doi: 10.1007/s10856-012-4675-6. [PMID: 22618272]
  • Ze Yun, Shuai Jin, Yuduan Ding, Zhuang Wang, Huijun Gao, Zhiyong Pan, Juan Xu, Yunjiang Cheng, Xiuxin Deng. Comparative transcriptomics and proteomics analysis of citrus fruit, to improve understanding of the effect of low temperature on maintaining fruit quality during lengthy post-harvest storage. Journal of experimental botany. 2012 May; 63(8):2873-93. doi: 10.1093/jxb/err390. [PMID: 22323274]
  • Richard A Becker, Don R Bergfelt, Susan Borghoff, Jeffrey P Davis, Bonnie T Hamby, John C O'Connor, A Michael Kaplan, Carol S Sloan, Rochelle W Tyl, Michael Wade, Mary Sue Marty. Interlaboratory study comparison of the 15-day intact adult male rat screening assay: evaluation of an antithyroid chemical and a negative control chemical. Birth defects research. Part B, Developmental and reproductive toxicology. 2012 Feb; 95(1):63-78. doi: 10.1002/bdrb.20343. [PMID: 22127959]
  • Jessie Fernandez, Janet D Wright, David Hartline, Cristian F Quispe, Nandakumar Madayiputhiya, Richard A Wilson. Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection. PLoS genetics. 2012; 8(5):e1002673. doi: 10.1371/journal.pgen.1002673. [PMID: 22570632]
  • Keiko Hosohata, Hitoshi Ando, Yoko Fujiwara, Akio Fujimura. Vanin-1: a potential biomarker for nephrotoxicant-induced renal injury. Toxicology. 2011 Nov; 290(1):82-8. doi: 10.1016/j.tox.2011.08.019. [PMID: 21907259]
  • Laura R Jarboe. YqhD: a broad-substrate range aldehyde reductase with various applications in production of biorenewable fuels and chemicals. Applied microbiology and biotechnology. 2011 Jan; 89(2):249-57. doi: 10.1007/s00253-010-2912-9. [PMID: 20924577]
  • Lijuan Peng, Gary R Kinsel. Characterization of plasma polymerized C, H, and O containing compounds by MALDI mass spectrometry. Langmuir : the ACS journal of surfaces and colloids. 2010 Nov; 26(22):17477-81. doi: 10.1021/la1027866. [PMID: 20961059]
  • Jayaram Bhandari, A Heather Fitzpatrick, Dring N Crowell. Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis. Plant physiology. 2010 Nov; 154(3):1116-27. doi: 10.1104/pp.110.157784. [PMID: 20807998]
  • Lolita Zaliauskiene, Ula Bernadisiute, Ausvydas Vareikis, Ricardas Makuska, Ieva Volungeviciene, Agne Petuskaite, Laurynas Riauba, Arunas Lagunavicius, Sarunas Zigmantas. Efficient gene transfection using novel cationic polymers poly(hydroxyalkylene imines). Bioconjugate chemistry. 2010 Sep; 21(9):1602-11. doi: 10.1021/bc900535k. [PMID: 20695432]
  • Andrew Shepherd, Peter W Piper. The Fps1p aquaglyceroporin facilitates the use of small aliphatic amides as a nitrogen source by amidase-expressing yeasts. FEMS yeast research. 2010 Aug; 10(5):527-34. doi: 10.1111/j.1567-1364.2010.00636.x. [PMID: 20491941]
  • Eric Block, A John Dane, Siji Thomas, Robert B Cody. Applications of direct analysis in real time mass spectrometry (DART-MS) in Allium chemistry. 2-propenesulfenic and 2-propenesulfinic acids, diallyl trisulfane S-oxide, and other reactive sulfur compounds from crushed garlic and other Alliums. Journal of agricultural and food chemistry. 2010 Apr; 58(8):4617-25. doi: 10.1021/jf1000106. [PMID: 20225897]
  • Soichi Ozaki, Yoshiyuki Ogata, Kunihiro Suda, Atsushi Kurabayashi, Tatsuya Suzuki, Naoki Yamamoto, Yoko Iijima, Taneaki Tsugane, Takashi Fujii, Chiaki Konishi, Shuji Inai, Somnuk Bunsupa, Mami Yamazaki, Daisuke Shibata, Koh Aoki. Coexpression analysis of tomato genes and experimental verification of coordinated expression of genes found in a functionally enriched coexpression module. DNA research : an international journal for rapid publication of reports on genes and genomes. 2010 Apr; 17(2):105-16. doi: 10.1093/dnares/dsq002. [PMID: 20130013]
  • Jen-Hsiang Tsai, Haw-Wen Chen, Yi-Wan Chen, Jer-Yuh Liu, Chong-Kuei Lii. The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT. Journal of biomedicine & biotechnology. 2010; 2010(?):486267. doi: 10.1155/2010/486267. [PMID: 20490359]
  • David Wenkert, Bernadette Ramirez, Yuehai Shen, Michael A Kron. In Vitro Activity of Geldanamycin Derivatives against Schistosoma japonicum and Brugia malayi. Journal of parasitology research. 2010; 2010(?):716498. doi: 10.1155/2010/716498. [PMID: 21253549]
  • M Kwolek-Mirek, S Bednarska, G Bartosz, T Biliński. Acrolein toxicity involves oxidative stress caused by glutathione depletion in the yeast Saccharomyces cerevisiae. Cell biology and toxicology. 2009 Aug; 25(4):363-78. doi: 10.1007/s10565-008-9090-x. [PMID: 18563599]
  • Ryusuke Fudouji, Takashi Tanaka, Toshitugu Taguri, Yosuke Matsuo, Isao Kouno. Coupling reactions of catechins with natural aldehydes and allyl alcohols and radical scavenging activities of the triglyceride-soluble products. Journal of agricultural and food chemistry. 2009 Jul; 57(14):6417-24. doi: 10.1021/jf9010998. [PMID: 19537756]
  • Shinobu Kitazume, Ritsuko Oka, Kazuko Ogawa, Satoshi Futakawa, Yoshiaki Hagiwara, Hajime Takikawa, Michio Kato, Akinori Kasahara, Eiji Miyoshi, Naoyuki Taniguchi, Yasuhiro Hashimoto. Molecular insights into beta-galactoside alpha2,6-sialyltransferase secretion in vivo. Glycobiology. 2009 May; 19(5):479-87. doi: 10.1093/glycob/cwp003. [PMID: 19150807]
  • Sarah N Campion, Cristina Tatis-Rios, Lisa M Augustine, Michael J Goedken, Nico van Rooijen, Nathan J Cherrington, José E Manautou. Effect of allyl alcohol on hepatic transporter expression: zonal patterns of expression and role of Kupffer cell function. Toxicology and applied pharmacology. 2009 Apr; 236(1):49-58. doi: 10.1016/j.taap.2009.01.007. [PMID: 19371622]
  • Soo Hyung Ryu, Young-Hwa Chung, Jae Kyun Lee, Jeong A Kim, Jung Woo Shin, Myoung Kuk Jang, Neung Hwa Park, Han Chu Lee, Yung Sang Lee, Dong Jin Suh. Antifibrogenic effects of tamoxifen in a rat model of periportal hepatic fibrosis. Liver international : official journal of the International Association for the Study of the Liver. 2009 Feb; 29(2):308-14. doi: 10.1111/j.1478-3231.2008.01811.x. [PMID: 18564211]
  • Meng Chen, Ting-Ting Hsieh, Shigemasa Osaki, Paul O Zamora, Ray Tsang. Improvement of surface lubricity of polymers and metals by a glow-discharge plasma cross-linking process. Journal of biomaterials science. Polymer edition. 2009; 20(4):511-27. doi: 10.1163/156856209x416511. [PMID: 19228451]
  • Richard M Lopachin, Brian C Geohagen, Terrence Gavin. Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal. Toxicological sciences : an official journal of the Society of Toxicology. 2009 Jan; 107(1):171-81. doi: 10.1093/toxsci/kfn226. [PMID: 18996889]
  • Kumiko Ueda, Yuriko Kawaguchi, Seigo Iwakawa. Effect of oxyethylene numbers on the pharmacokinetics of menatetrenone incorporated in oil-in-water lipid emulsions prepared with polyoxyethylene-polyoxypropylene block copolymers and soybean oil in rats. Biological & pharmaceutical bulletin. 2008 Dec; 31(12):2283-7. doi: 10.1248/bpb.31.2283. [PMID: 19043214]
  • Scott S Auerbach, Joel Mahler, Gregory S Travlos, Richard D Irwin. A comparative 90-day toxicity study of allyl acetate, allyl alcohol and acrolein. Toxicology. 2008 Nov; 253(1-3):79-88. doi: 10.1016/j.tox.2008.08.014. [PMID: 18817840]
  • José C Aponte, Manuela Verástegui, Edith Málaga, Mirko Zimic, Miguel Quiliano, Abraham J Vaisberg, Robert H Gilman, Gerald B Hammond. Synthesis, cytotoxicity, and anti-Trypanosoma cruzi activity of new chalcones. Journal of medicinal chemistry. 2008 Oct; 51(19):6230-4. doi: 10.1021/jm800812k. [PMID: 18798609]
  • Edward J Whittle, Amy E Tremblay, Peter H Buist, John Shanklin. Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 2008 Sep; 105(38):14738-43. doi: 10.1073/pnas.0805645105. [PMID: 18796606]
  • Hiroshi Murayama, Masaki Ikemoto, Yoshihiro Fukuda, Atsuo Nagata. Superiority of serum type-I arginase and ornithine carbamyltransferase in the detection of toxicant-induced acute hepatic injury in rats. Clinica chimica acta; international journal of clinical chemistry. 2008 May; 391(1-2):31-5. doi: 10.1016/j.cca.2008.01.023. [PMID: 18279670]
  • John C O'Connor, M Sue Marty, Richard A Becker, Suzanne Snajdr, A Michael Kaplan. Results of the negative control chemical allyl alcohol in the 15-day intact adult male rat screening assay for endocrine activity. Birth defects research. Part B, Developmental and reproductive toxicology. 2008 Apr; 83(2):117-22. doi: 10.1002/bdrb.20152. [PMID: 18383315]
  • J Stephen Clark, Carl A Baxter, Alexander G Dossetter, Stéphane Poigny, José L Castro, William G Whittingham. Stereoselective construction of the tricyclic core of neoliacinic acid. The Journal of organic chemistry. 2008 Feb; 73(3):1040-55. doi: 10.1021/jo702111u. [PMID: 18171077]
  • Volodymyr Ivanov, Saeid Rezaei Nejad, Shan Yi, Xiao Hui Wang. Physiological heterogeneity of suspended microbial aggregates. Water science and technology : a journal of the International Association on Water Pollution Research. 2008; 58(12):2435-41. doi: 10.2166/wst.2008.837. [PMID: 19092223]
  • I Chung, S H Kwon, S-T Shim, K H Kyung. Synergistic antiyeast activity of garlic oil and allyl alcohol derived from alliin in garlic. Journal of food science. 2007 Nov; 72(9):M437-40. doi: 10.1111/j.1750-3841.2007.00545.x. [PMID: 18034739]
  • G Tranfo, D Pigini, G Federici, S Bernardini, C Perricone, R Perricone. [Feasibility study of biological monitoring of chemical agents by means of evaluation of the effects on their in vitro effects on the complement system]. Giornale italiano di medicina del lavoro ed ergonomia. 2007 Jul; 29(3 Suppl):520-2. doi: NULL. [PMID: 18409809]
  • Marc C A Stuart, Jan van Esch, John C van de Pas, Jan B F N Engberts. Chain-length and solvent dependent morphological changes in sodium soap fibers. Langmuir : the ACS journal of surfaces and colloids. 2007 Jun; 23(12):6494-7. doi: 10.1021/la063633l. [PMID: 17488042]
  • M-K Shyu, R-H Yuan, J-C Shih, M-Z Wu, H-L Chen, Y-C Kuo, C-L Chien, L-P Chow, H-L Chen, F-J Hsieh. Kinetics and functional assay of liver repopulation after human cord blood transplantation. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2007 May; 39(5):455-65. doi: 10.1016/j.dld.2007.01.007. [PMID: 17379589]
  • Taku Chiba, Takemasa Takii, Kenji Nishimura, Yoshifumi Yamamoto, Hiroko Morikawa, Chiyoji Abe, Kikuo Onozaki. Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. Bioorganic & medicinal chemistry letters. 2007 May; 17(9):2487-91. doi: 10.1016/j.bmcl.2007.02.024. [PMID: 17331717]
  • Maria Notara, N A Bullett, Palavi Deshpande, David B Haddow, Sheila MacNeil, Julie T Daniels. Plasma polymer coated surfaces for serum-free culture of limbal epithelium for ocular surface disease. Journal of materials science. Materials in medicine. 2007 Feb; 18(2):329-38. doi: 10.1007/s10856-006-0697-2. [PMID: 17323166]
  • Rick D Irwin. NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice. Toxicity report series. 2006 Jul; ?(48):1-73, A1. doi: . [PMID: 17160105]
  • Sree D Panuganti, Farah D Khan, Craig K Svensson. Enhanced xenobiotic-induced hepatotoxicity and Kupffer cell activation by restraint-induced stress. The Journal of pharmacology and experimental therapeutics. 2006 Jul; 318(1):26-34. doi: 10.1124/jpet.106.100933. [PMID: 16569754]
  • R Sailaja, O H Setty. Protective effect of Phyllanthus fraternus against allyl alcohol-induced oxidative stress in liver mitochondria. Journal of ethnopharmacology. 2006 Apr; 105(1-2):201-9. doi: 10.1016/j.jep.2005.10.019. [PMID: 16359838]
  • Fragiska Sigala, Stamatis Theocharis, Konstantinos Sigalas, Sophia Markantonis-Kyroudis, Efstathios Papalabros, Aggeliki Triantafyllou, Georgia Kostopanagiotou, Ioanna Andreadou. Therapeutic value of melatonin in an experimental model of liver injury and regeneration. Journal of pineal research. 2006 Apr; 40(3):270-9. doi: 10.1111/j.1600-079x.2005.00310.x. [PMID: 16499564]
  • Ohm Divyam Krishna, Kwangmeyung Kim, Youngro Byun. Covalently grafted phospholipid monolayer on silicone catheter surface for reduction in platelet adhesion. Biomaterials. 2005 Dec; 26(34):7115-23. doi: 10.1016/j.biomaterials.2005.05.023. [PMID: 16009416]
  • S S Anand, M M Mumtaz, H M Mehendale. Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats. Archives of toxicology. 2005 Nov; 79(11):671-82. doi: 10.1007/s00204-005-0675-3. [PMID: 15940471]
  • Katey M Lemar, Ourania Passa, Miguel A Aon, Sonia Cortassa, Carsten T Müller, Sue Plummer, Brian O'Rourke, David Lloyd. Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans. Microbiology (Reading, England). 2005 Oct; 151(Pt 10):3257-3265. doi: 10.1099/mic.0.28095-0. [PMID: 16207909]
  • Wolfgang Völkel, Rubén Alvarez-Sánchez, Idelette Weick, Angela Mally, Wolfgang Dekant, Axel Pähler. Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats. Free radical biology & medicine. 2005 Jun; 38(11):1526-36. doi: 10.1016/j.freeradbiomed.2005.02.015. [PMID: 15890627]
  • Yuri Takahashi, Keisuke Yamato, Hidero Akiyama, Kazuyuki Tsuji, Hiraku Onishi, Yoshiharu Machida. Transdermal absorption of propofol in rats. Biological & pharmaceutical bulletin. 2005 May; 28(5):870-5. doi: 10.1248/bpb.28.870. [PMID: 15863896]
  • Ceren Susut, Richard B Timmons. Plasma enhanced chemical vapor depositions to encapsulate crystals in thin polymeric films: a new approach to controlling drug release rates. International journal of pharmaceutics. 2005 Jan; 288(2):253-61. doi: 10.1016/j.ijpharm.2004.10.004. [PMID: 15620865]
  • Shigeru Kurosawa, Hidenobu Aizawa, Zainal Abidin Talib, Björn Atthoff, Jöns Hilborn. Synthesis of tethered-polymer brush by atom transfer radical polymerization from a plasma-polymerized-film-coated quartz crystal microbalance and its application for immunosensors. Biosensors & bioelectronics. 2004 Dec; 20(6):1165-76. doi: 10.1016/j.bios.2004.06.034. [PMID: 15556363]
  • Sathanandam S Anand, Harihara M Mehendale. Liver regeneration: a critical toxicodynamic response in predictive toxicology. Environmental toxicology and pharmacology. 2004 Nov; 18(2):149-60. doi: 10.1016/j.etap.2004.02.011. [PMID: 21782744]
  • Lisa M Kaminskas, Simon M Pyke, Philip C Burcham. Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde. Organic & biomolecular chemistry. 2004 Sep; 2(18):2578-84. doi: 10.1039/b408796h. [PMID: 15351821]
  • Lisa M Kaminskas, Simon M Pyke, Philip C Burcham. Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice. The Journal of pharmacology and experimental therapeutics. 2004 Sep; 310(3):1003-10. doi: 10.1124/jpet.104.067330. [PMID: 15131244]
  • Fragiska Sigala, Georgia Kostopanagiotou, Ioanna Andreadou, Nikolaos Kavatzas, Evangelos Felekouras, Panagiotis Sigalas, Elias Bastounis, Efstathios Papalambros. Histological and lipid peroxidation changes after administration of 2-acetylaminofluorene in a rat liver injury model following selective periportal and pericentral damage. Toxicology. 2004 Mar; 196(1-2):155-63. doi: 10.1016/j.tox.2003.12.005. [PMID: 15036765]
  • K Valentová, A Moncion, I de Waziers, J Ulrichová. The effect of Smallanthus sonchifolius leaf extracts on rat hepatic metabolism. Cell biology and toxicology. 2004 Mar; 20(2):109-20. doi: 10.1023/b:cbto.0000027931.88957.80. [PMID: 15242186]
  • Philip C Burcham, Frank R Fontaine, Lisa M Kaminskas, Dennis R Petersen, Simon M Pyke. Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity. Molecular pharmacology. 2004 Mar; 65(3):655-64. doi: 10.1124/mol.65.3.655. [PMID: 14978244]
  • Sharmilee P Sawant, Ankur V Dnyanmote, Kartik Shankar, Pallavi B Limaye, John R Latendresse, Harihara M Mehendale. Potentiation of carbon tetrachloride hepatotoxicity and lethality in type 2 diabetic rats. The Journal of pharmacology and experimental therapeutics. 2004 Feb; 308(2):694-704. doi: 10.1124/jpet.103.058834. [PMID: 14610242]
  • Tamara R Knight, Marc W Fariss, Anwar Farhood, Hartmut Jaeschke. Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice. Toxicological sciences : an official journal of the Society of Toxicology. 2003 Nov; 76(1):229-36. doi: 10.1093/toxsci/kfg220. [PMID: 12944590]
  • Sathanandam S Anand, Subramanyam N Murthy, Vishal S Vaidya, Moiz M Mumtaz, Harihara M Mehendale. Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2003 Aug; 41(8):1123-32. doi: 10.1016/s0278-6915(03)00066-8. [PMID: 12842180]
  • Jane F Maddox, Robert A Roth, Patricia E Ganey. Allyl alcohol activation of protein kinase C delta leads to cytotoxicity of rat hepatocytes. Chemical research in toxicology. 2003 May; 16(5):609-15. doi: 10.1021/tx025655n. [PMID: 12755590]
  • Zdenek Dvorák, Pavel Kosina, Daniela Walterová, Vilím Simánek, Petr Bachleda, Jitka Ulrichová. Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum. Toxicology letters. 2003 Feb; 137(3):201-12. doi: 10.1016/s0378-4274(02)00406-x. [PMID: 12523963]
  • Katey M Lemar, Carsten T Müller, Susan Plummer, David Lloyd. Cell death mechanisms in the human opportunistic pathogen Candida albicans. The Journal of eukaryotic microbiology. 2003; 50 Suppl(?):685-6. doi: 10.1111/j.1550-7408.2003.tb00687.x. [PMID: 14736219]
  • Shawn Kinser, Bryan L Copple, Robert A Roth, Patricia E Ganey. Enhancement of allyl alcohol hepatotoxicity by endotoxin requires extrahepatic factors. Toxicological sciences : an official journal of the Society of Toxicology. 2002 Oct; 69(2):470-81. doi: 10.1093/toxsci/69.2.470. [PMID: 12377996]
  • Frank R Fontaine, Rachael A Dunlop, Dennis R Petersen, Philip C Burcham. Oxidative bioactivation of crotyl alcohol to the toxic endogenous aldehyde crotonaldehyde: association of protein carbonylation with toxicity in mouse hepatocytes. Chemical research in toxicology. 2002 Aug; 15(8):1051-8. doi: 10.1021/tx0255119. [PMID: 12184789]
  • Thomas P Johnston, James W Coker, Beverly J Paigen, Ossama Tawfik. Sex does not seem to influence the formation of aortic lesions in the P-407-induced mouse model of hyperlipidemia and atherosclerosis. Journal of cardiovascular pharmacology. 2002 Mar; 39(3):404-11. doi: 10.1097/00005344-200203000-00012. [PMID: 11862120]
  • Stefan W Toennes, Karl Schmidt, Anabel S Fandiño, Gerold F Kauert. A fatal human intoxication with the herbicide allyl alcohol (2-propen-1-ol). Journal of analytical toxicology. 2002 Jan; 26(1):55-7. doi: 10.1093/jat/26.1.55. [PMID: 11888018]
  • P E Ganey , Y W Barton, S Kinser, R A Sneed, C C Barton, R A Roth. Involvement of cyclooxygenase-2 in the potentiation of allyl alcohol-induced liver injury by bacterial lipopolysaccharide. Toxicology and applied pharmacology. 2001 Jul; 174(2):113-21. doi: 10.1006/taap.2001.9183. [PMID: 11446826]
  • A Iu Kovelenov, Iu V Lobzin, N N Pluzhnikova, D G D'iachkov. [Effect of perftoran on experimental hepatitis]. Eksperimental'naia i klinicheskaia farmakologiia. 2001 May; 64(3):41-4. doi: . [PMID: 11565505]
  • Y H Chung, J A Kim, B C Song, I H Song, M S Koh, H C Lee, E Yu, Y S Lee, D J Suh. Isocitrate dehydrogenase as a marker of centrilobular hepatic necrosis in the experimental model of rats. Journal of gastroenterology and hepatology. 2001 Mar; 16(3):328-32. doi: 10.1046/j.1440-1746.2001.02447.x. [PMID: 11339426]
  • A Lupp, M Tralls, U Fuchs, W Klinger. Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of different cytotoxins on cytochrome P450 mediated monooxygenase functions and on oxidative state. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2001 Feb; 52(6):529-38. doi: 10.1016/s0940-2993(01)80011-7. [PMID: 11256755]
  • M Y Moridani, S Khan, T Chan, S Teng, K Beard, P J O'Brien. Cytochrome P450 2E1 metabolically activates propargyl alcohol: propiolaldehyde-induced hepatocyte cytotoxicity. Chemico-biological interactions. 2001 Jan; 130-132(1-3):931-42. doi: 10.1016/s0009-2797(00)00246-5. [PMID: 11306107]
  • M Karas, S K Chakrabarti. Influence of caffeine on allyl alcohol-induced hepatotoxicity in rats. I. In vivo study. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2001; 20(2):141-54. doi: . [PMID: 11394713]
  • S A Moustafa. Effect of glutathione (GSH) depletion on the serum levels of triiodothyronine (T3), thyroxine (T4), and T3/T4 ratio in allyl alcohol-treated male rats and possible protection with zinc. International journal of toxicology. 2001 Jan; 20(1):15-20. doi: 10.1080/109158101750103332. [PMID: 11288928]
  • K Alam, M N Nagi, O A Al-Shabanah, A M Al-Bekairi. Beneficial effect of nitric oxide synthase inhibitor on hepatotoxicity induced by allyl alcohol. Journal of biochemical and molecular toxicology. 2001; 15(6):317-21. doi: 10.1002/jbt.10008. [PMID: 11835631]
  • M Karas, S K Chakrabarti. Caffeine potentiation of allyl alcohol-induced hepatotoxicity. II. In vitro study. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2001; 20(2):155-64. doi: ". [PMID: 11394714]
  • Janine C Harris, Sue Plummer, Michael P Turner, David Lloyd. The microaerophilic flagellate Giardia intestinalis: Allium sativum (garlic) is an effective antigiardial. Microbiology (Reading, England). 2000 Dec; 146 Pt 12(?):3119-3127. doi: 10.1099/00221287-146-12-3119. [PMID: 11101670]
  • R A Sneed, J P Buchweitz, P A Jean, P E Ganey. Pentoxifylline attenuates bacterial lipopolysaccharide-induced enhancement of allyl alcohol hepatotoxicity. Toxicological sciences : an official journal of the Society of Toxicology. 2000 Jul; 56(1):203-10. doi: 10.1093/toxsci/56.1.203. [PMID: 10869469]
  • R S Wang, T Nakajima, T Honma. Different change patterns of the isozymes of cytochrome P450 and glutathione S-transferases in chemically induced liver damage in rat. Industrial health. 1999 Oct; 37(4):440-8. doi: 10.2486/indhealth.37.440. [PMID: 10547960]
  • M G Soni, S K Ramaiah, M M Mumtaz, H Clewell, H M Mehendale. Toxicant-inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. Regulatory toxicology and pharmacology : RTP. 1999 Apr; 29(2 Pt 1):165-74. doi: 10.1006/rtph.1998.1280. [PMID: 10341147]
  • R A Sneed, S D Grimes, A E Schultze, A P Brown, P E Ganey. Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol. Toxicology and applied pharmacology. 1997 May; 144(1):77-87. doi: 10.1006/taap.1997.8115. [PMID: 9169072]
  • S Sell. Electron microscopic identification of putative liver stem cells and intermediate hepatocytes following periportal necrosis induced in rats by allyl alcohol. Stem cells (Dayton, Ohio). 1997; 15(5):378-85. doi: 10.1002/stem.150378. [PMID: 9323801]
  • S Khan, C Sood, P J O'Brien. The involvement of cytochrome P4502E1 in 2-bromoethanol-induced hepatocyte cytotoxicity. Pharmacology & toxicology. 1996 Apr; 78(4):241-8. doi: 10.1111/j.1600-0773.1996.tb00212.x. [PMID: 8861782]
  • L Atzori, L Congiu. Effect of verapamil on allyl alcohol hepatotoxicity. Drug metabolism and drug interactions. 1996; 13(2):87-98. doi: 10.1515/dmdi.1996.13.2.87. [PMID: 8905240]
  • S G Kim, S Y Nam, H C Chung, S Y Hong, K H Jung. Enhanced effectiveness of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in combination with garlic oil against experimental hepatic injury in rats and mice. The Journal of pharmacy and pharmacology. 1995 Aug; 47(8):678-82. doi: 10.1111/j.2042-7158.1995.tb05859.x. [PMID: 8583372]
  • P E Ganey, A E Schultze. Depletion of neutrophils and modulation of Kupffer cell function in allyl alcohol-induced hepatotoxicity. Toxicology. 1995 May; 99(1-2):99-106. doi: 10.1016/0300-483x(94)03005-m. [PMID: 7762005]
  • R J Rosengren, J M Sauer, S B Hooser, I G Sipes. The interactions between retinol and five different hepatotoxicants in the Swiss Webster mouse. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1995 May; 25(2):281-92. doi: 10.1006/faat.1995.1064. [PMID: 7665012]
  • J Liu, Y Liu, C D Klaassen. The effect of Chinese hepatoprotective medicines on experimental liver injury in mice. Journal of ethnopharmacology. 1994 May; 42(3):183-91. doi: 10.1016/0378-8741(94)90084-1. [PMID: 7934088]
  • P Bedossa, K Houglum, C Trautwein, A Holstege, M Chojkier. Stimulation of collagen alpha 1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: a link to tissue fibrosis?. Hepatology (Baltimore, Md.). 1994 May; 19(5):1262-71. doi: ". [PMID: 8175151]
  • M P Miguez, I Anundi, L A Sainz-Pardo, K O Lindros. Hepatoprotective mechanism of silymarin: no evidence for involvement of cytochrome P450 2E1. Chemico-biological interactions. 1994 Apr; 91(1):51-63. doi: 10.1016/0009-2797(94)90006-x. [PMID: 8194125]
  • Y J Surh, S S Lee. Enzymatic reduction of xenobiotic alpha,beta-unsaturated ketones: formation of allyl alcohol metabolites from shogaol and dehydroparadol. Research communications in chemical pathology and pharmacology. 1994 Apr; 84(1):53-61. doi: NULL. [PMID: 8042009]
  • L Ciccoli, C Signorini, C Alessandrini, M Ferrali, M Comporti. Iron release, lipid peroxidation, and morphological alterations of erythrocytes exposed to acrolein and phenylhydrazine. Experimental and molecular pathology. 1994 Apr; 60(2):108-18. doi: 10.1006/exmp.1994.1010. [PMID: 8070539]
  • E Maellaro, B Del Bello, L Sugherini, A Pompella, A F Casini, M Comporti. Protection by ascorbic acid against oxidative injury of isolated hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems. 1994 Mar; 24(3):281-9. doi: 10.3109/00498259409043239. [PMID: 8009890]
  • M Z Badr. Controversial role of intracellular iron in the mechanisms of chemically-induced hepatotoxicity. Journal of biochemical toxicology. 1994 Feb; 9(1):25-9. doi: 10.1002/jbt.2570090105. [PMID: 8151629]