acetamide (BioDeep_00001867616)
Main id: BioDeep_00000006099
PANOMIX_OTCML-2023
代谢物信息卡片
acetamide
化学式: C2H5NO (59.0371)
中文名称: 乙酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)N
InChI: InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:49028
- ChEBI: CHEBI:27856
- KEGG: C06244
- PubChem: 178
- DrugBank: DB02736
- ChEMBL: CHEMBL16081
- CAS: 74330-92-0
- CAS: 60-35-5
- MetaboLights: MTBLC27856
- PubChem: 8483
- PDB-CCD: ACM
- 3DMET: B00928
- NIKKAJI: J2.339F
- RefMet: Acetamide
- KNApSAcK: 27856
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 1485683 - Convolvulus erinaceus: 10.1007/BF00563774
- 452768 - Haplophyllum acutifolium: 10.1007/BF00568641
- 181124 - Marasmius oreades: 10.1139/V89-210
- 4463 - Sauromatum venosum: 10.1016/S0031-9422(00)94756-3
- 29760 - Vitis vinifera: 10.3389/FMICB.2017.00457
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- William Nguyen, Coralie Boulet, Madeline G Dans, Katie Loi, Kate E Jarman, Gabrielle M Watson, Wai-Hong Tham, Kate J Fairhurst, Tomas Yeo, David A Fidock, Sergio Wittlin, Mrittika Chowdury, Tania F de Koning-Ward, Gong Chen, Dandan Yan, Susan A Charman, Delphine Baud, Stephen Brand, Paul F Jackson, Alan F Cowman, Paul R Gilson, Brad E Sleebs. Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein.
European journal of medicinal chemistry.
2024 Apr; 270(?):116354. doi:
10.1016/j.ejmech.2024.116354. [PMID: 38554474] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Vartika Srivastava, Mohmmad Younus Wani, Abdullah Saad Al-Bogami, Aijaz Ahmad. Piperidine based 1,2,3-triazolylacetamide derivatives induce cell cycle arrest and apoptotic cell death in Candida auris.
Journal of advanced research.
2021 03; 29(?):121-135. doi:
10.1016/j.jare.2020.11.002. [PMID: 33842010] - Qi Zhang, Peipei Yuan, Meng Li, Yang Fu, Ying Hou, Yaping Sun, Liyuan Gao, Yaxin Wei, Weisheng Feng, Xiaoke Zheng. Effect of phenylacetamide isolated from lepidium apetalum on myocardial injury in spontaneously hypertensive rats and its possible mechanism.
Pharmaceutical biology.
2020 Dec; 58(1):597-609. doi:
10.1080/13880209.2020.1778043. [PMID: 32631115] - Abdul Kadir, Sadaf Ibrahim, Syed Nudrat Nawaid Shah, Zara Aslam, Rehan Ahmed Siddiqui, Mirza Tasawer Baig, Muhammad Raza Shah, Talat Mirza, Shabana Usman Simjee, Adeel Arsalan. Attenuation of cisplatin-induced acute kidney injury by N-(2-Hydroxyphenyl) acetamide and its gold conjugated nano-formulations in mice.
Pakistan journal of pharmaceutical sciences.
2020 Mar; 33(2(Supplementary)):787-793. doi:
NULL. [PMID: 32863253] - Maureen Hamilton, Andrew L Consiglio, Kyle MacEwen, A Joe Shaw, Vasiliki Tsakraklides. Identification of a Yarrowia lipolytica acetamidase and its use as a yeast genetic marker.
Microbial cell factories.
2020 Feb; 19(1):22. doi:
10.1186/s12934-020-1292-9. [PMID: 32024536] - Rance Nault, Bryan Bals, Farzaneh Teymouri, Michael B Black, Melvin E Andersen, Patrick D McMullen, Seetha Krishnan, Nagesh Kuravadi, Neetha Paul, Santhosh Kumar, Kamala Kannan, K C Jayachandra, Lakshmanan Alagappan, Bhavesh Dhirajlal Patel, Kenneth T Bogen, Bhaskar B Gollapudi, James E Klaunig, Tim R Zacharewski, Venkataraman Bringi. A toxicogenomic approach for the risk assessment of the food contaminant acetamide.
Toxicology and applied pharmacology.
2020 02; 388(?):114872. doi:
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Regulatory toxicology and pharmacology : RTP.
2019 Nov; 108(?):104451. doi:
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2018 Jun; 10(11):863-875. doi:
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2017 Oct; 137(?):54-57. doi:
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Medicine.
2017 Jul; 96(27):e7256. doi:
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2017 Jun; 23(21):3890-3899. doi:
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Bioorganic & medicinal chemistry.
2016 11; 24(21):5455-5461. doi:
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Bioresource technology.
2016 Oct; 218(?):123-8. doi:
10.1016/j.biortech.2016.05.120. [PMID: 27359060] - Jun Li, Michael L Schulte, Michael L Nickels, H Charles Manning. New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO.
Bioorganic & medicinal chemistry letters.
2016 08; 26(15):3472-7. doi:
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Environmental science & technology.
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2013 Feb; 114(2):282-93. doi:
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2012 Oct; 73(10):1512-8. doi:
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Journal of integrative plant biology.
2012 Jul; 54(7):471-85. doi:
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Animal reproduction science.
2012 Jun; 132(3-4):155-8. doi:
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Water research.
2012 May; 46(8):2515-24. doi:
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Microbial ecology.
2012 Feb; 63(2):460-70. doi:
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Tuberculosis research and treatment.
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Journal of lipids.
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BMC cancer.
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Current genetics.
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PloS one.
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International journal of molecular sciences.
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Frontiers in molecular neuroscience.
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Frontiers in microbiology.
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Molecular microbiology.
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European journal of histochemistry : EJH.
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2010 Mar; 73(3):331-7. doi:
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Marine drugs.
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Bioscience, biotechnology, and biochemistry.
2009 Sep; 73(9):1940-7. doi:
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PloS one.
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Bioconjugate chemistry.
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American journal of physiology. Regulatory, integrative and comparative physiology.
2009 Aug; 297(2):R313-22. doi:
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Bioorganic & medicinal chemistry.
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2009 Aug; 30(15):2632-9. doi:
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Chemical reviews.
2009 May; 109(5):1793-899. doi:
10.1021/cr030440j. [PMID: 19265398] - Geeta Godara, Craig Smith, Janine Bosse, Mark Zeidel, John Mathai. Functional characterization of Actinobacillus pleuropneumoniae urea transport protein, ApUT.
American journal of physiology. Regulatory, integrative and comparative physiology.
2009 Apr; 296(4):R1268-73. doi:
10.1152/ajpregu.90726.2008. [PMID: 19144751] - Yoonkyung Kim, Athena M Klutz, Béatrice Hechler, Zhan-Guo Gao, Christian Gachet, Kenneth A Jacobson. Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors.
Purinergic signalling.
2009 Mar; 5(1):39-50. doi:
10.1007/s11302-008-9113-3. [PMID: 18600474] - Wen-Xia Fan, Xue-Hu Ma, Dan Ge, Tian-Qing Liu, Zhan-Feng Cui. Cryoprotectants for the vitrification of corneal endothelial cells.
Cryobiology.
2009 Feb; 58(1):28-36. doi:
10.1016/j.cryobiol.2008.10.124. [PMID: 18976647] - Annamaria Buschini, Lisa Ferrarini, Susanna Franzoni, Serena Galati, Mirca Lazzaretti, Francesca Mussi, Cristina Northfleet de Albuquerque, Tânia Maria Araújo Domingues Zucchi, Paola Poli. Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.
Journal of parasitology research.
2009; 2009(?):463575. doi:
10.1155/2009/463575. [PMID: 20981287] - Carol M Ulloa, Allen Towfigh, Joseph Safdieh. Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures.
Neuropsychiatric disease and treatment.
2009; 5(?):467-76. doi:
10.2147/ndt.s4844. [PMID: 19777068] - Wei-Lie Xiao, Sheng-Xiong Huang, Rui-Rui Wang, Jia-Liang Zhong, Xue-Mei Gao, Fei He, Jian-Xin Pu, Yang Lu, Yong-Tang Zheng, Qi-Tai Zheng, Han-Dong Sun. Nortriterpenoids and lignans from Schisandra sphenanthera.
Phytochemistry.
2008 Nov; 69(16):2862-6. doi:
10.1016/j.phytochem.2008.09.010. [PMID: 18951592] - Athena M Klutz, Zhan-Guo Gao, John Lloyd, Asher Shainberg, Kenneth A Jacobson. Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.
Journal of nanobiotechnology.
2008 Oct; 6(?):12. doi:
10.1186/1477-3155-6-12. [PMID: 18947419] - Alex C Varghese, Stefan S du Plessis, Tommaso Falcone, Ashok Agarwal. Cryopreservation/transplantation of ovarian tissue and in vitro maturation of follicles and oocytes: challenges for fertility preservation.
Reproductive biology and endocrinology : RB&E.
2008 Oct; 6(?):47. doi:
10.1186/1477-7827-6-47. [PMID: 18828928] - Ruyi Xue, Zhenxin Lin, Chunhui Deng, Ling Dong, Taotao Liu, Jiyao Wang, Xizhong Shen. A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2008 Oct; 22(19):3061-8. doi:
10.1002/rcm.3708. [PMID: 18767022] - Chang-Tong Yang, Young-Seung Kim, Jianjun Wang, Lijun Wang, Jiyun Shi, Zi-Bo Li, Xiaoyuan Chen, Ming Fan, Jian-Jian Li, Shuang Liu. 64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics.
Bioconjugate chemistry.
2008 Oct; 19(10):2008-22. doi:
10.1021/bc8002056. [PMID: 18763821] - Christopher V Kelly, Pascale R Leroueil, Bradford G Orr, Mark M Banaszak Holl, Ioan Andricioaei. Poly(amidoamine) dendrimers on lipid bilayers II: Effects of bilayer phase and dendrimer termination.
The journal of physical chemistry. B.
2008 Aug; 112(31):9346-53. doi:
10.1021/jp8013783. [PMID: 18620451] - Christopher V Kelly, Pascale R Leroueil, Elizabeth K Nett, Jeffery M Wereszczynski, James R Baker, Bradford G Orr, Mark M Banaszak Holl, Ioan Andricioaei. Poly(amidoamine) dendrimers on lipid bilayers I: Free energy and conformation of binding.
The journal of physical chemistry. B.
2008 Aug; 112(31):9337-45. doi:
10.1021/jp801377a. [PMID: 18620450] - Laureen C Colis, Paromita Raychaudhury, Ashis K Basu. Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta.
Biochemistry.
2008 Aug; 47(31):8070-9. doi:
10.1021/bi800529f. [PMID: 18616294] - . Toxicology and carcinogenesis studies of formamide (Cas No. 75-12-7) in F344/N rats and B6C3F1 mice (gavage studies).
National Toxicology Program technical report series.
2008 Jul; ?(541):1-192. doi:
. [PMID: 18716632] - Bassel Abou-Khalil. Levetiracetam in the treatment of epilepsy.
Neuropsychiatric disease and treatment.
2008 Jun; 4(3):507-23. doi:
10.2147/ndt.s2937. [PMID: 18830435] - Tuula M Kalliomäki, Gordon McCallum, Sarah Jane Lunt, Peter G Wells, Richard P Hill. Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model.
BMC cancer.
2008 May; 8(?):151. doi:
10.1186/1471-2407-8-151. [PMID: 18507854] - Holger A Lindner, Margot Täfler-Naumann, Klaus-Heinrich Röhm. N-acetylamino acid utilization by kidney aminoacylase-1.
Biochimie.
2008 May; 90(5):773-80. doi:
10.1016/j.biochi.2007.12.006. [PMID: 18222180] - Carole Gauthier, Fabienne Clerisse, Jacques Dommes, Marie-France Jaspar-Versali. Characterization and cloning of chitin deacetylases from Rhizopus circinans.
Protein expression and purification.
2008 May; 59(1):127-37. doi:
10.1016/j.pep.2008.01.013. [PMID: 18314348] - Bryce Maciver, Craig P Smith, Warren G Hill, Mark L Zeidel. Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes.
American journal of physiology. Renal physiology.
2008 Apr; 294(4):F956-64. doi:
10.1152/ajprenal.00229.2007. [PMID: 18256317] - Stephen C Alley, Dennis R Benjamin, Scott C Jeffrey, Nicole M Okeley, Damon L Meyer, Russell J Sanderson, Peter D Senter. Contribution of linker stability to the activities of anticancer immunoconjugates.
Bioconjugate chemistry.
2008 Mar; 19(3):759-65. doi:
10.1021/bc7004329. [PMID: 18314937] - D L Garzón, D S Peñaranda, L Pérez, F Marco-Jiménez, X Espert, T Müller, M Jover, J F Asturiano. Effects of pH, sodium bicarbonate, cryoprotectants and foetal bovine serum on the cryopreservation of European eel sperm.
Reproduction in domestic animals = Zuchthygiene.
2008 Feb; 43(1):99-105. doi:
10.1111/j.1439-0531.2007.00861.x. [PMID: 18199265] - Koichi Takao, Tomohiro Ozawa, Satoko Shibata, Makiko Wada, Yoshiaki Sugita, Akira Shirahata, Keijiro Samejima. Formation of spermidine or norspermidine from synthetic diacetylpolyamines by acetylpolyamine oxidase in cultured cells.
Biological & pharmaceutical bulletin.
2007 Dec; 30(12):2389-93. doi:
10.1248/bpb.30.2389. [PMID: 18057731] - Nathan A Stasko, C Bryce Johnson, Mark H Schoenfisch, Timothy A Johnson, Ekhson L Holmuhamedov. Cytotoxicity of polypropylenimine dendrimer conjugates on cultured endothelial cells.
Biomacromolecules.
2007 Dec; 8(12):3853-9. doi:
10.1021/bm7008203. [PMID: 18004811] - Tinggang Li, Junxin Liu, Renbi Bai, Dieudonne-Guy Ohandja, Fook-Sin Wong. Biodegradation of organonitriles by adapted activated sludge consortium with acetonitrile-degrading microorganisms.
Water research.
2007 Aug; 41(15):3465-73. doi:
10.1016/j.watres.2007.04.033. [PMID: 17544472] - Keisuke Edashige, Satoshi Ohta, Mitsunobu Tanaka, Tatsunaga Kuwano, Delgado M Valdez, Takao Hara, Bo Jin, Sei-ichi Takahashi, Shinsuke Seki, Chihiro Koshimoto, Magosaburo Kasai. The role of aquaporin 3 in the movement of water and cryoprotectants in mouse morulae.
Biology of reproduction.
2007 Aug; 77(2):365-75. doi:
10.1095/biolreprod.106.059261. [PMID: 17429015] - Dan Zhao, N D Sonawane, Marc H Levin, Baoxue Yang. Comparative transport efficiencies of urea analogues through urea transporter UT-B.
Biochimica et biophysica acta.
2007 Jul; 1768(7):1815-21. doi:
10.1016/j.bbamem.2007.04.010. [PMID: 17506977] - Robert M Burk, David F Woodward. A historical perspective and recent advances in prostamide research and therapeutics.
Current opinion in drug discovery & development.
2007 Jul; 10(4):413-21. doi:
NULL. [PMID: 17659482] - John Cuppoletti, Danuta H Malinowska, Kirti P Tewari, Jayati Chakrabarti, Ryuji Ueno. Cellular and molecular effects of unoprostone as a BK channel activator.
Biochimica et biophysica acta.
2007 May; 1768(5):1083-92. doi:
10.1016/j.bbamem.2006.12.015. [PMID: 17307133] - S M Rutherfurd, T M Kitson, A D Woolhouse, M C McGrath, W H Hendriks. Felinine stability in the presence of selected urine compounds.
Amino acids.
2007 Feb; 32(2):235-42. doi:
10.1007/s00726-006-0369-z. [PMID: 16868647] - Yasushi Okuda, Yasunari Seita, Shin Hisamatsu, Shigenori Sonoki, Masao Shino, Toshio Masaoka, Tomo Inomata, Shin-ichi Kamijo, Naomi Kashiwazaki. Fertility of spermatozoa cryopreserved with 2\% acetamide or glycerol through artificial insemination in the Japanese white rabbit.
Experimental animals.
2007 Jan; 56(1):29-34. doi:
10.1538/expanim.56.29. [PMID: 17283888] - A Junaidi, P E Williamson, G B Martin, P G Stanton, M A Blackberry, J M Cummins, T E Trigg. Pituitary and testicular endocrine responses to exogenous gonadotrophin-releasing hormone (GnRH) and luteinising hormone in male dogs treated with GnRH agonist implants.
Reproduction, fertility, and development.
2007; 19(8):891-8. doi:
10.1071/rd07088. [PMID: 18076821] - Kiran A Kulkarni, Samiksha Katiyar, Avadhesha Surolia, Mamannamana Vijayan, Kaza Suguna. Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc.
Acta crystallographica. Section D, Biological crystallography.
2006 Nov; 62(Pt 11):1319-24. doi:
10.1107/s0907444906028198. [PMID: 17057334] - Mariano Pertino, Jaime A Rodríguez, Cristina Theoduloz, Iván Razmilic, Guillermo Schmeda-Hirschmann. Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives.
The Journal of pharmacy and pharmacology.
2006 Nov; 58(11):1507-13. doi:
10.1211/jpp.58.11.0012. [PMID: 17132214] - Naomi Kashiwazaki, Yasushi Okuda, Yasunari Seita, Shin Hisamatsu, Shigenori Sonoki, Masao Shino, Toshio Masaoka, Tomo Inomata. Comparison of glycerol, lactamide, acetamide and dimethylsulfoxide as cryoprotectants of Japanese white rabbit spermatozoa.
The Journal of reproduction and development.
2006 Aug; 52(4):511-6. doi:
10.1262/jrd.18008. [PMID: 16679717] - Ming-Rong Zhang, Masanao Ogawa, Jun Maeda, Takehito Ito, Junko Noguchi, Katsushi Kumata, Takashi Okauchi, Tetsuya Suhara, Kazutoshi Suzuki. [2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.
Journal of medicinal chemistry.
2006 May; 49(9):2735-42. doi:
10.1021/jm060006k. [PMID: 16640334] - Tyrone B Hayes, Paola Case, Sarah Chui, Duc Chung, Cathryn Haeffele, Kelly Haston, Melissa Lee, Vien Phoung Mai, Youssra Marjuoa, John Parker, Mable Tsui. Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?.
Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):40-50. doi:
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