Quebrachitol (BioDeep_00001867505)
Main id: BioDeep_00000407572
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C7H14O6 (194.079)
中文名称: L-白雀木醇, 左旋水杨糖醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1C(C(C(C(C1O)O)O)O)O
InChI: InChI=1S/C7H14O6/c1-13-7-5(11)3(9)2(8)4(10)6(7)12/h2-12H,1H3/t2?,3-,4-,5+,6+,7?/m0/s1
描述信息
L-Quebrachitol is a member of cyclohexanols.
L-Quebrachitol is a natural product found in Croton cortesianus, Hippophae rhamnoides, and other organisms with data available.
L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1].
L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway[1].
同义名列表
28 个代谢物同义名
(1R,2S,3S,4S,5R,6R)-6-Methoxycyclohexane-1,2,3,4,5-pentaol; (1R,2S,3S,4S,5R,6R)-6-methoxycyclohexane-1,2,3,4,5-pentol; (1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol; 6-methoxycyclohexane-1,2,3,4,5-pentol; 2B678708-4698-466E-88D8-3443A058E849; Inositol, 2-O-methyl-, L-chiro-; quebrachitol, (L-chiro)-isomer; L-chiro-Inositol, 2-O-methyl-; D-chiro-Inositol, 2-O-methyl-; L-chiro-Inositol,2-O-methyl-; 1L-2-O-methyl-chiro-inositol; 2-O-Methyl-L-chiro-inositol; DSCFFEYYQKSRSV-FIZWYUIZSA-N; 2-O-methyl-chiro-inositol; L-(-)-2-O-Methylinositol; 2-O-methylchiroinositol; Inositol, 2-O-methyl-; Quebrachitol, (-)-; Quebrachitol, L-; (-)-Quebrachitol; UNII-9W4JLQ7I4W; L-Quebrachitol; quebrachitol; Pinitol TMS; 9W4JLQ7I4W; Quebrachit; Brahol; (-)-Quebrachitol
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:170050
- ChEBI: CHEBI:111
- KEGG: C08257
- PubChem: 151108
- ChEMBL: CHEMBL501109
- Wikipedia: Quebrachitol
- MeSH: quebrachitol
- ChemIDplus: 0000642386
- CAS: 3564-07-6
- CAS: 642-38-6
- medchemexpress: HY-N2375
- PubChem: 10456
- KNApSAcK: C00001169
- NIKKAJI: J16.953F
- KNApSAcK: 111
- LOTUS: LTS0190476
- wikidata: Q100899778
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
12 个相关的物种来源信息
- 259893 - Artemisia argyi Lévl.et Vant.: -
- 401898 - Artemisia gmelinii:
- 265784 - Artemisia iwayomogi:
- 1475389 - Croton cortesianus: 10.1016/0031-9422(92)80479-X
- 241838 - Excoecaria agallocha: 10.1016/S0044-328X(84)80097-5
- 201003 - Harpullia arborea: 10.1016/J.FITOTE.2008.04.010
- 193516 - Hippophae rhamnoides: 10.1007/BF00565192
- 556999 - Magonia pubescens: 10.1016/J.PHYMED.2007.09.002
- 387710 - Mandevilla martiana: 10.1002/PTR.865
- 33090 - Plants: -
- 3972 - Viscum album: 10.1111/J.1469-8137.1992.TB02943.X
- 569835 - Zanha africana:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sonali Mishra, Saurabh Kumar, Ramdas, Sonam Khare, Aparna Shukla, Karuna Shanker, Anirban Pal, Feroz Khan, Mahendra P Darokar. Quebrachitol from Putranjiva roxburghii Wall. (Putranjivaceae) a potent antimalarial: Pre-clinical efficacy and its interaction with PfLDH.
Parasitology international.
2023 Feb; 92(?):102675. doi:
10.1016/j.parint.2022.102675. [PMID: 36089201] - Vijayakumar Karuppiah, Ramanathan Thirunanasambandham. Quebrachitol from Rhizophora mucronata inhibits biofilm formation and virulence production in Staphylococcus epidermidis by impairment of initial attachment and intercellular adhesion.
Archives of microbiology.
2020 Aug; 202(6):1327-1340. doi:
10.1007/s00203-020-01844-9. [PMID: 32146497] - María Yolanda Rios, Ismael León-Rivera, Ramiro Ríos-Gomez, Liliana C Córdova-Albores, Angelica Berenice Aguilar-Guadarrama. Phytotoxic and nematicide evaluation of Croton ehrenbergii (Euphorbiaceae).
Pest management science.
2019 Aug; 75(8):2158-2165. doi:
10.1002/ps.5336. [PMID: 30637916] - Zi-Chen Wu, Jie-Qiong Zhang, Jie-Tang Zhao, Jian-Guo Li, Xu-Ming Huang, Hui-Cong Wang. Biosynthesis of quebrachitol, a transportable photosynthate, in Litchi chinensis.
Journal of experimental botany.
2018 03; 69(7):1649-1661. doi:
10.1093/jxb/erx483. [PMID: 29281092] - Martina Díaz, Andrés González, Ian Castro-Gamboa, David Gonzalez, Carmen Rossini. First record of L-quebrachitol in Allophylus edulis (Sapindaceae).
Carbohydrate research.
2008 Oct; 343(15):2699-700. doi:
10.1016/j.carres.2008.07.014. [PMID: 18715552] - Ahmed A Mahmoud, Ahmed A Ahmed. Alpha-pinene-type monoterpenes and other constituents from Artemisia suksdorfii.
Phytochemistry.
2006 Oct; 67(19):2103-9. doi:
10.1016/j.phytochem.2006.06.013. [PMID: 16860353] - H V Nobre Júnior, G M A Cunha, M O Moraes, M F D Luciana, R A Oliveira, F D Maia, M A S Nogueira, T L G Lemos, V S Rao. Quebrachitol (2-O-methyl-L-inositol) attenuates 6-hydroxydopamine-induced cytotoxicity in rat fetal mesencephalic cell cultures.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2006 Sep; 44(9):1544-51. doi:
10.1016/j.fct.2006.04.002. [PMID: 16797817] - Telma L G Lemos, Luciana L Machado, João S N Souza, Aluisio M Fonseca, Juliana L Maia, Otilia D L Pessoa. Antioxidant, icthyotoxicity and brine shrimp lethality tests of Magonia glabrata.
Fitoterapia.
2006 Sep; 77(6):443-5. doi:
10.1016/j.fitote.2006.04.008. [PMID: 16828535] - Wei Xiang, Rong-Tao Li, Yun-Ling Mao, Hong-Jie Zhang, Sheng-Hong Li, Qi-Shi Song, Han-Dong Sun. Four new prenylated isoflavonoids in Tadehagi triquetrum.
Journal of agricultural and food chemistry.
2005 Jan; 53(2):267-71. doi:
10.1021/jf0483117. [PMID: 15656660] - A Falshaw, J B Hart, P C Tyler. New syntheses of 1D- and 1L-1,2-anhydro-myo-inositol and assessment of their glycosidase inhibitory activities.
Carbohydrate research.
2000 Nov; 329(2):301-8. doi:
10.1016/s0008-6215(00)00192-0. [PMID: 11117313] - M AUROUSSEAU, E LAGRANGE, F ROQUET. [STUDY OF SOME PHARMACODYNAMIC PROPERTIES OF A LAXATIVE SUBSTANCE OF PLANT ORIGIN: QUEBRACHITOL].
Therapie.
1964 Jul; 19(?):1071-83. doi:
". [PMID: 14190934]
