Dibutyl succinate (BioDeep_00000001777)
Secondary id: BioDeep_00001868075
human metabolite blood metabolite
代谢物信息卡片
2,4-Dinitrofluorobenzene Sulfonic Acid
化学式: C12H22O4 (230.1518)
中文名称: 丁二酸二丁酯, 琥珀酸二丁酯
谱图信息:
最多检出来源 Homo sapiens(blood) 75%
分子结构信息
SMILES: CCCCOC(=O)CCC(=O)OCCCC
InChI: InChI=1S/C12H22O4/c1-3-5-9-15-11(13)7-8-12(14)16-10-6-4-2/h3-10H2,1-2H3
描述信息
P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03B - Insecticides and repellents
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:82263
- KEGG: C19143
- PubChem: 8830
- HMDB: HMDB0251173
- Metlin: METLIN72884
- DrugBank: DB13332
- ChEMBL: CHEMBL1788388
- CAS: 141-03-7
- PMhub: MS000001157
- PubChem: 124489815
- KNApSAcK: 82263
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Valéria Costa Da Silva, Gerlane Coelho Bernardo Guerra, Daline Fernandes De Souza Araújo, Edilane Rodrigues De Araújo, Aurigena Antunes De Araújo, Renato Dantas-Medeiros, Ana Caroline Zanatta, Isadora Luisa Gomes Da Silva, Raimundo Fernandes De Araújo Júnior, Debora Esposito, Marvin Moncada, Silvana Maria Zucolotto. Chemopreventive and immunomodulatory effects of phenolic-rich extract of Commiphora leptophloeos against inflammatory bowel disease: Preclinical evidence.
Journal of ethnopharmacology.
2024 Jun; 328(?):118025. doi:
10.1016/j.jep.2024.118025. [PMID: 38458342] - Stefania Lama, Ester Pagano, Francesca Borrelli, Maria Maisto, Gian Carlo Tenore, Maria Francesca Nanì, Pilar Chacon-Millan, Ettore Novellino, Paola Stiuso. Polyphenol-Rich Extract from 'Limoncella' Apple Variety Ameliorates Dinitrobenzene Sulfonic Acid-Induced Colitis and Linked Liver Damage.
International journal of molecular sciences.
2024 Mar; 25(6):. doi:
10.3390/ijms25063210. [PMID: 38542183] - Tommaso Venneri, Giada Giorgini, Nadine Leblanc, Nicolas Flamand, Francesca Borrelli, Cristoforo Silvestri, Vincenzo Di Marzo. Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice.
Lipids in health and disease.
2023 May; 22(1):63. doi:
10.1186/s12944-023-01823-1. [PMID: 37189092] - José R Cruz-Muñoz, Tonatiuh Barrios-García, Eduardo E Valdez-Morales, María F Durán-Vazquez, Karen B Méndez-Rodríguez, Alma Barajas-Espinosa, Fernando Ochoa-Cortes, María C Martínez-Saldaña, Yenny A Gómez-Aguirre, Raquel Guerrero Alba. Ethanolic extract from Lepidium virginicum L. ameliorates DNBS-induced colitis in rats.
Journal of ethnopharmacology.
2022 May; 289(?):115056. doi:
10.1016/j.jep.2022.115056. [PMID: 35104576] - Emiliano Manzo, Aniello Schiano Moriello, Francesco Tinto, Roberta Verde, Marco Allarà, Luciano De Petrocellis, Ester Pagano, Angelo A Izzo, Vincenzo Di Marzo, Stefania Petrosino. A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator.
Cells.
2021 02; 10(2):. doi:
10.3390/cells10020450. [PMID: 33672574] - Carmen Parisio, Elena Lucarini, Laura Micheli, Alessandra Toti, Maria Bellumori, Lorenzo Cecchi, Laura Calosi, Daniele Bani, Lorenzo Di Cesare Mannelli, Nadia Mulinacci, Carla Ghelardini. Extra virgin olive oil and related by-products (Olea europaea L.) as natural sources of phenolic compounds for abdominal pain relief in gastrointestinal disorders in rats.
Food & function.
2020 Dec; 11(12):10423-10435. doi:
10.1039/d0fo02293d. [PMID: 33237043] - Valéria Costa da Silva, Aurigena Antunes de Araújo, Daline Fernandes de Souza Araújo, Maíra Conceição Jerônimo Souza Lima, Roseane Carvalho Vasconcelos, Raimundo Fernandes de Araújo Júnior, Silvana Maria Zucolotto Langasnner, Matheus de Freitas Fernandes Pedrosa, Caroline Addison Carvalho Xavier de Medeiros, Gerlane Coelho Bernardo Guerra. Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats.
International journal of molecular sciences.
2018 Dec; 19(12):. doi:
10.3390/ijms19124016. [PMID: 30545135] - Marika Cordaro, Daniela Impellizzeri, Enrico Gugliandolo, Rosalba Siracusa, Rosalia Crupi, Emanuela Esposito, Salvatore Cuzzocrea. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease.
Molecular pharmacology.
2016 Nov; 90(5):549-561. doi:
10.1124/mol.116.105668. [PMID: 27625036] - Noureddine Bribi, Francesca Algieri, Alba Rodriguez-Nogales, Teresa Vezza, Jose Garrido-Mesa, María Pilar Utrilla, María Del Mar Contreras, Fadila Maiza, Antonio Segura-Carretero, Maria Elena Rodriguez-Cabezas, Julio Gálvez. Intestinal anti-inflammatory effects of total alkaloid extract from Fumaria capreolata in the DNBS model of mice colitis and intestinal epithelial CMT93 cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2016 Aug; 23(9):901-13. doi:
10.1016/j.phymed.2016.05.003. [PMID: 27387398] - Nidhi Goyal, Ajay Rana, Krishna Reddy V Bijjem, Puneet Kumar. Effect of chenodeoxycholic acid and sodium hydrogen sulfide in dinitro benzene sulfonic acid (DNBS)--Induced ulcerative colitis in rats.
Pharmacological reports : PR.
2015 Jun; 67(3):616-23. doi:
10.1016/j.pharep.2014.12.018. [PMID: 25933978] - Vijay Morampudi, Ganive Bhinder, Xiujuan Wu, Chuanbin Dai, Ho Pan Sham, Bruce A Vallance, Kevan Jacobson. DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat.
Journal of visualized experiments : JoVE.
2014 Feb; ?(84):e51297. doi:
10.3791/51297. [PMID: 24637969] - Isabelle Olivier, Vassilia Theodorou, Philippe Valet, Isabelle Castan-Laurell, Laurent Ferrier, Hélène Eutamène. Modifications of mesenteric adipose tissue during moderate experimental colitis in mice.
Life sciences.
2014 Jan; 94(1):1-7. doi:
10.1016/j.lfs.2013.09.028. [PMID: 24215755] - Helena Shifrin, Mirela Nadler-Milbauer, Shai Shoham, Marta Weinstock. Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses.
PloS one.
2013; 8(2):e57668. doi:
10.1371/journal.pone.0057668. [PMID: 23469045] - D Strøbæk, D T Brown, D P Jenkins, Y-J Chen, N Coleman, Y Ando, P Chiu, S Jørgensen, J Demnitz, H Wulff, P Christophersen. NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.
British journal of pharmacology.
2013 Jan; 168(2):432-44. doi:
10.1111/j.1476-5381.2012.02143.x. [PMID: 22891655] - Sheila M Innis, Chuanbin Dai, Xiujuan Wu, Alison M J Buchan, Kevan Jacobson. Perinatal lipid nutrition alters early intestinal development and programs the response to experimental colitis in young adult rats.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Dec; 299(6):G1376-85. doi:
10.1152/ajpgi.00258.2010. [PMID: 20864654] - Joshua Ka-Shun Ko, Cecilia Wai-Shan Chik. The protective action of radix Astragalus membranaceus against hapten-induced colitis through modulation of cytokines.
Cytokine.
2009 Aug; 47(2):85-90. doi:
10.1016/j.cyto.2009.05.014. [PMID: 19539495] - Emanuela Esposito, Emanuela Mazzon, Luisa Riccardi, Rocco Caminiti, Rosaria Meli, Salvatore Cuzzocrea. Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis.
Journal of pineal research.
2008 Sep; 45(2):166-73. doi:
10.1111/j.1600-079x.2008.00572.x. [PMID: 18429971] - Jean-Eric Ghia, Patricia Blennerhassett, Stephen M Collins. Vagus nerve integrity and experimental colitis.
American journal of physiology. Gastrointestinal and liver physiology.
2007 Sep; 293(3):G560-7. doi:
10.1152/ajpgi.00098.2007. [PMID: 17585014] - Jean Eric Ghia, Patricia Blennerhassett, Harry Kumar-Ondiveeran, Elena F Verdu, Stephen M Collins. The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model.
Gastroenterology.
2006 Oct; 131(4):1122-30. doi:
10.1053/j.gastro.2006.08.016. [PMID: 17030182] - Joshua-Ka-Shun Ko, Flora-Ying-Lee Lam, Andrew-Pok-Lap Cheung. Amelioration of experimental colitis by Astragalus membranaceus through anti-oxidation and inhibition of adhesion molecule synthesis.
World journal of gastroenterology.
2005 Oct; 11(37):5787-94. doi:
10.3748/wjg.v11.i37.5787. [PMID: 16270386] - Jeffrey R Scott, Alison E Fox-Robichaud. Hepatic leukocyte recruitment in a model of acute colitis.
American journal of physiology. Gastrointestinal and liver physiology.
2002 Sep; 283(3):G561-6. doi:
10.1152/ajpgi.00462.2001. [PMID: 12181168] - S Sturiale, G Barbara, B Qiu, M Figini, P Geppetti, N Gerard, C Gerard, E F Grady, N W Bunnett, S M Collins. Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P.
Proceedings of the National Academy of Sciences of the United States of America.
1999 Sep; 96(20):11653-8. doi:
10.1073/pnas.96.20.11653. [PMID: 10500232]
