Deoxyribose 5-phosphate (BioDeep_00000001746)
Secondary id: BioDeep_00000400396, BioDeep_00001869794
natural product human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
化学式: C5H11O7P (214.0242)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(otcml) 8.48%
分子结构信息
SMILES: C1C(C(OC1O)COP(=O)(O)O)O
InChI: InChI=1S/C5H11O7P/c6-3-1-5(7)12-4(3)2-11-13(8,9)10/h3-7H,1-2H2,(H2,8,9,10)/t3-,4+,5+/m0/s1
描述信息
Deoxyribose 5-phosphate is a a metabolite in the pentose phosphate pathway. It can be generated from D-glyceraldehdye-3 phosphate via the enzyme 2-Deoxyribose 5-phosphate aldolase (DERA). Alternately Deoxyribose 5-phosphate can be converted to D-glyceraldehyde-3 phosphate that can then feed into the pentose phosphate pathway. Deoxyribose 5-phosphate can also be generated from 2-Deoxy-D-ribose via the enzyme Ribokinase (EC 2.7.1.15). It has been shown in a number of organisms that deoxynucleosides or deoxyriboses cause the induction of aldolases (such as DERA) involved in their catabolism, leading to the utilisation of the pentose moiety as carbon and energy source. [HMDB]
Deoxyribose 5-phosphate is a a metabolite in the pentose phosphate pathway. It can be generated from D-glyceraldehdye-3 phosphate via the enzyme 2-Deoxyribose 5-phosphate aldolase (DERA). Alternately Deoxyribose 5-phosphate can be converted to D-glyceraldehyde-3 phosphate that can then feed into the pentose phosphate pathway. Deoxyribose 5-phosphate can also be generated from 2-Deoxy-D-ribose via the enzyme Ribokinase (EC 2.7.1.15). It has been shown in a number of organisms that deoxynucleosides or deoxyriboses cause the induction of aldolases (such as DERA) involved in their catabolism, leading to the utilisation of the pentose moiety as carbon and energy source.
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID D026
同义名列表
16 个代谢物同义名
{[(2R,3S,5R)-3,5-dihydroxyoxolan-2-yl]methoxy}phosphonic acid; 2-Deoxy-alpha-delta-ribose 5-phosphate; 2-Deoxyribose-5-phosphate sodium salt; 2-Deoxy-D-ribofuranose 5-phosphate; 2-Deoxy-alpha-D-ribose 5-phosphate; Deoxyribose 5-phosphoric acid; 2-Deoxy-D-ribose-5-phosphate; 2-Deoxy-D-ribose 5-phosphate; 2-Deoxyribose 5-phosphate; 2-Deoxyribose-5-phosphate; Deoxyribose 5-phosphate; Deoxyribose-5-phosphate; 2-Deoxyribose-5-p; Deoxy-ribose-5P; Deoxyribose-5-p; CHEMBL1161472
数据库引用编号
30 个数据库交叉引用编号
- ChEBI: CHEBI:190741
- ChEBI: CHEBI:55513
- KEGG: C00673
- PubChem: 45934311
- PubChem: 439288
- PubChem: 635
- HMDB: HMDB0001031
- Metlin: METLIN63109
- Metlin: METLIN3349
- foodb: FDB022380
- chemspider: 25057464
- CAS: 102916-66-5
- CAS: 7685-50-9
- MoNA: KO000568
- MoNA: PS015007
- MoNA: KO000564
- MoNA: PS015009
- MoNA: KO000566
- MoNA: KO000567
- MoNA: KO000565
- MoNA: PR100525
- MoNA: PS015002
- PMhub: MS000001087
- ChEBI: CHEBI:16132
- PubChem: 3942
- PDB-CCD: AAB
- PDB-CCD: ORP
- 3DMET: B04714
- NIKKAJI: J993.340I
- RefMet: Deoxyribose 5-phosphate
分类词条
相关代谢途径
Reactome(0)
BioCyc(2)
PlantCyc(0)
代谢反应
21 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(4)
- superpathway of ribose and deoxyribose phosphate degradation:
H2O + deoxycytidine ⟶ ammonia + deoxyuridine - (deoxy)ribose phosphate degradation:
H2O + deoxycytidine ⟶ ammonia + deoxyuridine - (deoxy)ribose phosphate degradation:
deoxyuridine + phosphate ⟶ deoxyribose 1-phosphate + uracil - superpathway of ribose and deoxyribose phosphate degradation:
deoxyuridine + phosphate ⟶ deoxyribose 1-phosphate + uracil
WikiPathways(0)
Plant Reactome(0)
INOH(1)
- Pentose phosphate cycle ( Pentose phosphate cycle ):
ATP + D-Ribose 5-phosphate ⟶ AMP + D-5-Phospho-ribosyl 1-diphosphate
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(16)
- Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Glucose-6-phosphate Dehydrogenase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Ribose-5-phosphate Isomerase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Transaldolase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Purine Deoxyribonucleosides Degradation:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Glucose-6-phosphate Dehydrogenase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Ribose-5-phosphate Isomerase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Transaldolase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Pentose Phosphate Pathway:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Glucose-6-phosphate Dehydrogenase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Ribose-5-phosphate Isomerase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate - Transaldolase Deficiency:
Adenosine triphosphate + D-Ribose 5-phosphate ⟶ Adenosine monophosphate + Phosphoribosyl pyrophosphate
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
