2-Oxo-3-methylvalerate (BioDeep_00000015107)

Main id: BioDeep_00000265241

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


(+-)-3-Methyl-2-oxovaleric acid sodium salt

化学式: C6H10O3 (130.063)
中文名称: 3-甲基-2-氧代戊酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(C)C(=O)C(=O)O
InChI: InChI=1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)

描述信息

CONFIDENCE standard compound; ML_ID 14
3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.

同义名列表

7 个代谢物同义名

(+-)-3-Methyl-2-oxovaleric acid sodium salt; (3S)-3-Methyl-2-oxopentanoic acid; 3-Methyl-2-oxopentanoic acid; 3-Methyl-2-oxovaleric acid; 2-Oxo-3-methylvaleic acid; 2-Oxo-3-methylvalerate; 3-Methyl-2-oxopentanoate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 CASP3, CAT, FASN, KHK, MAPK14, MMUT, MTOR, NEFH, PRKX, S100B
Peripheral membrane protein 2 ACHE, MTOR
Endoplasmic reticulum membrane 3 MTOR, PROS1, PSEN1
Nucleus 8 ACHE, CASP3, EBF1, MAPK14, MTOR, PRKX, PSEN1, S100B
cytosol 7 CASP3, CAT, FASN, KHK, MAPK14, MTOR, S100B
dendrite 2 MTOR, PSEN1
phagocytic vesicle 1 MTOR
centrosome 1 PSEN1
nucleoplasm 6 CASP3, MAPK14, MTOR, PRKX, PSEN1, S100B
Cell membrane 3 ACHE, PSEN1, TNF
Cytoplasmic side 1 MTOR
Cell projection, axon 2 NEFH, PSEN1
Cell projection, growth cone 1 PSEN1
Cytoplasmic granule 1 PSEN1
Early endosome membrane 1 PSEN1
Multi-pass membrane protein 1 PSEN1
Golgi apparatus membrane 2 MTOR, PSEN1
Synapse 2 ACHE, PSEN1
cell cortex 1 PSEN1
cell junction 1 PSEN1
cell surface 3 ACHE, PSEN1, TNF
ciliary rootlet 1 PSEN1
dendritic shaft 1 PSEN1
gamma-secretase complex 1 PSEN1
glutamatergic synapse 3 CASP3, MAPK14, PSEN1
Golgi apparatus 3 ACHE, FASN, PSEN1
Golgi membrane 4 INS, MTOR, PROS1, PSEN1
growth cone 1 PSEN1
lysosomal membrane 3 EGF, MTOR, PSEN1
mitochondrial inner membrane 1 PSEN1
neuromuscular junction 2 ACHE, PSEN1
neuronal cell body 4 CASP3, PSEN1, S100B, TNF
postsynapse 1 PSEN1
presynaptic membrane 1 PSEN1
sarcolemma 1 PSEN1
smooth endoplasmic reticulum 1 PSEN1
synaptic vesicle 1 PSEN1
Lysosome 1 MTOR
plasma membrane 8 ACHE, EGF, FASN, IGHE, KNG1, PROS1, PSEN1, TNF
Membrane 6 ACHE, CAT, EGF, FASN, MTOR, PSEN1
axon 2 NEFH, PSEN1
extracellular exosome 6 CAT, EGF, FASN, KHK, KNG1, PROS1
Lysosome membrane 1 MTOR
endoplasmic reticulum 2 PROS1, PSEN1
extracellular space 9 ACHE, EGF, IGHE, IL6, INS, KNG1, PROS1, S100B, TNF
perinuclear region of cytoplasm 2 ACHE, S100B
Schaffer collateral - CA1 synapse 1 NEFH
mitochondrion 4 CAT, MAPK14, MMUT, PSEN1
protein-containing complex 2 CAT, PSEN1
intracellular membrane-bounded organelle 2 CAT, S100B
Microsome membrane 1 MTOR
postsynaptic density 2 CASP3, NEFH
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 IGHE
Secreted 5 ACHE, IL6, INS, PROS1, S100B
extracellular region 11 ACHE, CAT, EGF, IGHE, IL6, INS, KNG1, MAPK14, PROS1, S100B, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
Mitochondrion matrix 1 MMUT
mitochondrial matrix 2 CAT, MMUT
Extracellular side 1 ACHE
nuclear membrane 1 PSEN1
external side of plasma membrane 1 TNF
Early endosome 1 PSEN1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 PSEN1, TNF
Cytoplasm, cytoskeleton 1 NEFH
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 1 MTOR
collagen-containing extracellular matrix 1 KNG1
nuclear speck 1 MAPK14
nuclear outer membrane 1 PSEN1
ruffle 1 S100B
Cell projection, neuron projection 1 PSEN1
neuron projection 1 PSEN1
chromatin 1 EBF1
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
cytoskeleton 1 NEFH
Secreted, extracellular space 1 KNG1
spindle pole 1 MAPK14
blood microparticle 2 KNG1, PROS1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 IGHE
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
Melanosome 1 FASN
side of membrane 1 ACHE
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 2 INS, PROS1
endoplasmic reticulum lumen 3 IL6, INS, KNG1
platelet alpha granule lumen 3 EGF, KNG1, PROS1
kinetochore 1 PSEN1
transport vesicle 1 INS
azurophil granule membrane 1 PSEN1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
aggresome 1 PSEN1
neurofilament 1 NEFH
clathrin-coated endocytic vesicle membrane 1 EGF
synaptic cleft 1 ACHE
death-inducing signaling complex 1 CASP3
Rough endoplasmic reticulum 1 PSEN1
Cytoplasmic vesicle, phagosome 1 MTOR
[Isoform 3]: Cell membrane 1 IGHE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
postsynaptic intermediate filament cytoskeleton 1 NEFH
neurofibrillary tangle 1 NEFH
[Isoform H]: Cell membrane 1 ACHE
glycogen granule 1 FASN
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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