N-Acetylarylamine (BioDeep_00000001437)
Secondary id: BioDeep_00000405741
human metabolite Endogenous
描述信息
N-Acetylarylamine is an odourless solid chemical of leaf or flake-like appearance. It is also known as acetanilide, N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin. N-Acetylarylamine has analgesic and fever-reducing properties; it is in the same class of drugs as acetaminophen (paracetamol). Under the name acetanilid it formerly figured in the formula of a number of patent medicines and over the counter drugs. In 1948, Julius Axelrod and Bernard Brodie discovered that acetanilide is much more toxic in these applications than other drugs, causing methemoglobinemia and ultimately doing damage to the liver and kidneys. As such, acetanilide has largely been replaced by less toxic drugs, in particular acetaminophen, which is a metabolite of acetanilide and whose use Axelrod and Brodie suggested in the same study.
Acetanilide has analgesic and fever-reducing properties; it is in the same class of drugs as acetaminophen (paracetamol). Under the name acetanilid it formerly figured in the formula of a number of patent medicines and over the counter drugs. In 1948, Julius Axelrod and Bernard Brodie discovered that acetanilide is much more toxic in these applications than other drugs, causing methemoglobinemia and ultimately doing damage to the liver and kidneys. As such, acetanilide has largely been replaced by less toxic drugs, in particular acetaminophen, which is a metabolite of acetanilide and whose use Axelrod and Brodie suggested in the same study.
KEIO_ID A130
同义名列表
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:28884
- KEGG: C07565
- KEGGdrug: D72485
- PubChem: 904
- HMDB: HMDB0001250
- Metlin: METLIN6107
- ChEMBL: CHEMBL269644
- Wikipedia: N-Phenylacetamide
- foodb: FDB022512
- chemspider: 880
- CAS: 55576-55-1
- CAS: 1449-75-8
- CAS: 103-84-4
- MoNA: KO000198
- MoNA: KO000199
- MoNA: KO002293
- MoNA: KO002297
- MoNA: KO002296
- MoNA: KO000196
- MoNA: KO002294
- MoNA: KO002295
- MoNA: KO000195
- MoNA: KO000197
- PMhub: MS000000525
- PubChem: 9768
- NIKKAJI: J4.023A
- RefMet: N-Acetylarylamine
- KNApSAcK: 28884
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
2 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(2)
- Arylamine metabolism:
N-Acetylarylamine ⟶ Arylamine - Arylamine metabolism:
N-Acetylarylamine ⟶ N-hydroxy-N-acetylamine
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 906689 - Dendrobium catenatum: 10.1021/NP900252F
- 154293 - Dendrobium huoshanense: 10.1021/NP900252F
- 142614 - Dendrobium moniliforme: 10.1021/NP900252F
- 142615 - Dendrobium officinale: 10.1021/NP900252F
- 9606 - Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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