2-Phenylglycine (BioDeep_00000001197)

 

Secondary id: BioDeep_00001868925

human metabolite Endogenous blood metabolite


代谢物信息卡片


DL-alpha-Aminophenylacetic acid

化学式: C8H9NO2 (151.0633254)
中文名称: Alpha-氨基苯乙酸, DL-苯甘氨酸, L-(+)-α-苯甘氨酸, 2-苯甘氨酸
谱图信息: 最多检出来源 Homo sapiens(urine) 10.1%

分子结构信息

SMILES: C1=CC=C(C=C1)C(C(=O)O)N
InChI: InChI=1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)

描述信息

2-Phenylglycine, also known as a-amino-a-toluate or L-PHG amino acid, belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). Outside of the human body, 2-Phenylglycine has been detected, but not quantified in cow milk. This could make 2-phenylglycine a potential biomarker for the consumption of these foods. 2-Phenylglycine is a metabolite described in normal human urine (PMID 14473597) and plasma (PMID 5888801).
2-Phenylglycine is a metabolite described in normal human urine (PMID 14473597) and plasma (PMID 5888801) [HMDB]

同义名列表

57 个代谢物同义名

DL-alpha-Aminophenylacetic acid; DL-alpha-Phenylaminoacetic acid; alpha-Amino-benzeneacetic acid; alpha-Aminobenzeneacetic acid; alpha-Amino-alpha-toluic acid; alpha-Aminophenylacetic acid; 2-Phenylglycine, (DL)-isomer; DL-a-Aminophenylacetic acid; DL-alpha-Phenylaminoacetate; 2-Phenylglycine, (D)-isomer; DL-alpha-Aminophenylacetate; 2-Phenylglycine, (L)-isomer; 2-Amino-2-phenylacetic acid; alpha-Amino-benzeneacetate; alpha-Aminobenzeneacetate; (+/-)-alpha-phenylglycine; Α-aminobenzeneacetic acid; a-Aminobenzeneacetic acid; alpha-Amino-alpha-toluate; Amino(phenyl)acetic acid; Α-aminophenylacetic acid; alpha-Aminophenylacetate; Amino-phenyl-acetic acid; 2-Aminophenylacetic acid; a-Aminophenylacetic acid; 2-Amino-2-phenylacetate; DL-a-Aminophenylacetate; DL-alpha-Phenylglycine; Aminophenylacetic acid; Α-aminobenzeneacetate; a-Amino-a-toluic acid; (+/-)-α-phenylglycine; Α-amino-α-toluic acid; (+/-)-a-phenylglycine; a-Aminobenzeneacetate; Α-aminophenylacetate; Amino(phenyl)acetate; a-Aminophenylacetate; Amino-phenyl-acetate; DL-2-Phenyl-glycine; DL-Α-phenylglycine; alpha-Phenylgycine; DL-a-Phenylglycine; DL-2-Phenylglycine; Α-amino-α-toluate; a-Amino-a-toluate; L-PHG Amino acid; DL-Phenylglycine; 2-Phenyl-glycine; Α-phenylglycine; a-Phenylglycine; 2-Phenylglycine; D-Phenylglycine; L-Phenylglycine; Phenylglycine; H-Phg-OH; 2-Phenylglycine



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hong Zhang, Cailong Zhao, Huanlin Zheng, Xiaocui Chen, Biao Chen, Zhibing Wu. Design, Synthesis and Bioassay of 2-Phenylglycine Derivatives as Potential Pesticide Candidates. Chemistry & biodiversity. 2023 Jan; 20(1):e202200957. doi: 10.1002/cbdv.202200957. [PMID: 36515624]
  • Alan C Foster, Natalie Rangel-Diaz, Ursula Staubli, Jia-Ying Yang, Mahmud Penjwini, Veena Viswanath, Yong-Xin Li. Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor-mediated LTP in rat visual cortex slices. Neuropharmacology. 2017 Nov; 126(?):70-83. doi: 10.1016/j.neuropharm.2017.08.010. [PMID: 28807674]
  • Karin Halbmair, Janine Wegner, Ulf Diederichsen, Marina Bennati. Pulse EPR Measurements of Intramolecular Distances in a TOPP-Labeled Transmembrane Peptide in Lipids. Biophysical journal. 2016 Dec; 111(11):2345-2348. doi: 10.1016/j.bpj.2016.10.022. [PMID: 27836102]
  • Yawei Zhao, Rongrong Feng, Guosong Zheng, Jinzhong Tian, Lijun Ruan, Mei Ge, Weihong Jiang, Yinhua Lu. Involvement of the TetR-Type Regulator PaaR in the Regulation of Pristinamycin I Biosynthesis through an Effect on Precursor Supply in Streptomyces pristinaespiralis. Journal of bacteriology. 2015 Jun; 197(12):2062-71. doi: 10.1128/jb.00045-15. [PMID: 25868645]
  • Sookie La, Ahrrum Kim, Jung-Han Kim, One-Kyun Choi, Kyoung-Rae Kim. Profiling and screening analysis of 27 aromatic amino acids by capillary electrophoresis in dual modes. Electrophoresis. 2002 Apr; 23(7-8):1080-9. doi: 10.1002/1522-2683(200204)23:7/8<1080::aid-elps1080>3.0.co;2-f. [PMID: 11981855]