2-Hydroxyphenethylamine (BioDeep_00000001193)

 

Secondary id: BioDeep_00000405413

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


2-amino-1-phenylethan-1-ol

化学式: C8H11NO (137.0841)
中文名称: 2-氨基-1-苯乙醇, 2-羟基苯乙胺
谱图信息: 最多检出来源 Homo sapiens(plant) 12.99%

Reviewed

Last reviewed on 2024-09-26.

Cite this Page

2-Hydroxyphenethylamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/2-hydroxyphenethylamine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001193). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C(C=C1)C(CN)O
InChI: InChI=1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2

描述信息

2-Hydroxyphenethylamine, also known as beta-phenethanolamine or 2-amino-1-phenylethanol, belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group. It is the simplest member of the class of phenylethanolamines that is 2-aminoethanol bearing a phenyl substituent at the 1-position. 2-Hydroxyphenethylamine exists in all living organisms, ranging from bacteria to humans. 2-Hydroxyphenethylamine ia an amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists.
Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry. [HMDB]
2-Amino-1-phenylethanol is an analogue of noradrenaline.

同义名列表

39 个代谢物同义名

DL-beta-Phenyl-beta-hydroxyethylamine; beta-Hydroxy-beta-phenyl-ethylamine; beta-Hydroxy-beta-phenylethylamine; alpha-(Aminomethyl)benzyl alcohol; a-(Aminomethyl)benzyl alcohol; Α-(aminomethyl)benzyl alcohol; Β-hydroxy-β-phenylethylamine; 2-Phenyl-2-hydroxyethylamine; beta-Hydroxyphenylethylamine; 2-Hydroxy-2-phenylethylamine; b-Hydroxy-b-phenylethylamine; beta-Hydroxy-phenethylamine; 2-amino-1-Phenyl-1-ethanol; 2-amino-1-phenylethan-1-ol; beta-Hydroxyphenethylamine; beta Hydroxyphenethylamine; 2-amino-1-Phenylethanol-1; b-Hydroxyphenethylamine; beta Phenylethanolamine; 2-Amino-1-phenylethanol; 2-Hydroxyphenethylamine; beta-Phenylethanolamine; 2 Hydroxyphenethylamine; Β-hydroxyphenethylamine; beta-Phenethanolamine; 2 Phenylethanolamine; 2-Phenylethanolamine; β phenylethanolamine; b-Phenylethanolamine; Β-phenylethanolamine; b-Phenethanolamine; phenylethanolamine; Β-phenethanolamine; Hydroxyethylamine; Phenethanolamine; Bisnorephedrine; 2-Hydroxyphenethylamine; 2-Amino-1-phenylethanol; Phenylethanolamine



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

41 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADRA1A, ALB, AOC3, DBH, DDC, GRIN1, GRIN2B, SND1, TH
Endosome membrane 1 ADRB2
Endoplasmic reticulum membrane 4 GRIN1, GRIN2B, PNMT, SPP1
Mitochondrion membrane 1 PNMT
Nucleus 6 ADRA1A, ADRB2, ALB, APCS, SND1, TH
cytosol 8 ADRA1A, ALB, COMT, DDC, PNMT, SND1, SST, TH
dendrite 4 COMT, GRIN1, HTR6, TH
mitochondrial membrane 1 PNMT
centrosome 1 ALB
nucleoplasm 1 ADRA1A
Cell membrane 9 ADRA1A, ADRB2, ADRB3, AOC3, COMT, GRIN1, GRIN2B, HTR6, SPP1
Cell projection, axon 1 TH
Multi-pass membrane protein 9 ADRA1A, ADRB2, ADRB3, GRIN1, GRIN2B, HTR6, PNMT, SPP1, UCP1
Synapse 5 COMT, DBH, GRIN1, HTR6, TAC1
cell surface 3 AOC3, GRIN1, GRIN2B
Golgi apparatus 4 ADRB2, ALB, AOC3, SPP1
Golgi membrane 1 INS
mitochondrial inner membrane 1 UCP1
neuronal cell body 2 SST, TAC1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 2 GRIN1, TH
Lysosome 2 ADRB2, GRIN2B
endosome 1 ADRB2
plasma membrane 9 ADRA1A, ADRB2, ADRB3, AOC3, COMT, GRIN1, GRIN2B, HTR6, SPP1
terminal bouton 2 GRIN1, TH
Membrane 7 ADRB2, AOC3, COMT, DBH, GRIN1, GRIN2B, SND1
apical plasma membrane 1 ADRB2
axon 3 COMT, TAC1, TH
caveola 1 ADRA1A
extracellular exosome 6 ALB, APCS, COMT, DDC, SND1, SPP1
endoplasmic reticulum 4 ALB, AOC3, DBH, PNMT
extracellular space 7 ALB, APCS, DBH, INS, SPP1, SST, TAC1
perinuclear region of cytoplasm 2 SPP1, TH
mitochondrion 3 PNMT, TH, UCP1
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 4 ADRA1A, COMT, DBH, PNMT
postsynaptic density 2 GRIN1, GRIN2B
Secreted 6 ALB, APCS, DBH, INS, SPP1, SST
extracellular region 7 ALB, APCS, DBH, INS, SPP1, SST, TAC1
cytoplasmic side of plasma membrane 1 TH
excitatory synapse 1 GRIN1
Extracellular side 1 COMT
anchoring junction 1 ALB
centriolar satellite 1 DBH
Nucleus membrane 1 ADRA1A
nuclear membrane 1 ADRA1A
dendritic spine 1 GRIN1
perikaryon 1 TH
cytoplasmic vesicle 1 TH
Melanosome membrane 1 TH
Early endosome 2 ADRB2, AOC3
Single-pass type II membrane protein 3 AOC3, COMT, DBH
postsynaptic membrane 2 GRIN1, GRIN2B
Cytoplasm, perinuclear region 1 TH
Mitochondrion inner membrane 1 UCP1
Cytoplasm, cytoskeleton 1 GRIN2B
GABA-ergic synapse 1 SST
collagen-containing extracellular matrix 1 APCS
Postsynaptic cell membrane 2 GRIN1, GRIN2B
Late endosome 1 GRIN2B
receptor complex 2 ADRB2, ADRB3
neuron projection 3 GRIN1, GRIN2B, TH
ciliary basal body 1 ALB
cilium 1 HTR6
cell projection 1 SPP1
cytoskeleton 1 GRIN2B
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, APCS
endosome lumen 1 INS
microvillus 1 AOC3
Membrane, caveola 1 ADRA1A
[Isoform 1]: Endoplasmic reticulum membrane 1 PNMT
Cell projection, dendrite 1 GRIN2B
Melanosome 1 SND1
Synaptic cell membrane 1 GRIN1
synaptic membrane 2 GRIN1, GRIN2B
secretory granule lumen 2 DBH, INS
secretory granule membrane 1 DBH
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, INS, SPP1
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
postsynaptic density membrane 2 GRIN1, GRIN2B
neuronal dense core vesicle 2 ADRB2, SST
clathrin-coated endocytic vesicle membrane 1 ADRB2
synaptic cleft 1 GRIN1
NMDA selective glutamate receptor complex 2 GRIN1, GRIN2B
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
[Isoform 2]: Endoplasmic reticulum membrane 1 PNMT
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
transport vesicle membrane 1 DBH
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
ciliary transition fiber 1 ALB
dense body 1 SND1
RNAi effector complex 1 SND1


文献列表

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