Zamamistatin (BioDeep_00000011550)

代谢物信息卡片

Aeroplysinin I

化学式: C9H9Br2NO3 (336.8949)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(Br)C(O)C(O)(CC#N)C=C1Br
InChI: InChI=1S/C9H9Br2NO3/c1-15-7-5(10)4-9(14,2-3-12)8(13)6(7)11/h4,8,13-14H,2H2,1H3/t8-,9-/m0/s1

描述信息

同义名列表

4 个代谢物同义名

Aeroplysinin I; Aeroplysinin 1; Zamamistatin; Aeroplysinin 1

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:80925
KEGG: C17099
PubChem: 100308
Metlin: METLIN71558
ChEMBL: CHEMBL462153
KNApSAcK: C00048927
CAS: 28656-91-9
CAS: 55057-73-3
PMhub: MS000025608
PubChem: 96023572
KNApSAcK: C00038366
NIKKAJI: J17.043G
KNApSAcK: 80925
LOTUS: LTS0198927
wikidata: Q27151425

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

261677 - Aiolochroia crassa:
121476 - Aplysina:
289389 - Aplysina aerophoba:
289390 - Aplysina archeri: 10.1016/0040-4020(96)00518-2
289398 - Aplysina cauliformis: 10.1021/NP9805138
121477 - Aplysina cavernicola: 10.1016/S0040-4020(97)00311-6
202113 - Aplysina fistularis:
1504326 - Callyspongia tenerrima: 10.1021/NP9805138
283601 - Pseudoceratina: 10.1016/0305-1978(95)00013-K
375148 - Pseudoceratina arabica: 10.1007/BF01954262
1162762 - Pseudoceratina durissima: 10.1071/CH9870341
154632 - Tylodina perversa: 10.1016/S0305-1978(99)00024-1
289407 - Verongula gigantea:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	11	ANG, ANXA5, CASP3, CASP7, CHEK1, CTNNB1, EGFR, HIF1A, MSMP, PDGFRA, PTGS2
Peripheral membrane protein	3	ANXA5, GORASP1, PTGS2
Endosome membrane	1	EGFR
Endoplasmic reticulum membrane	4	EGFR, HMOX1, PDGFRA, PTGS2
Nucleus	10	ANG, CASP3, CASP7, CHEK1, CTNNB1, EGFR, H2AX, HIF1A, HMOX1, PDGFRA
cytosol	9	ANG, ANXA5, CASP3, CASP7, CHEK1, CTNNB1, HIF1A, HMOX1, NRK
nuclear body	1	HIF1A
centrosome	3	CHEK1, CTNNB1, H2AX
nucleoplasm	8	CASP3, CASP7, CHEK1, CTNNB1, H2AX, HIF1A, HMOX1, PDGFRA
RNA polymerase II transcription regulator complex	1	HIF1A
Cell membrane	4	CTNNB1, EGFR, ITGAM, PDGFRA
Cytoplasmic side	2	GORASP1, HMOX1
lamellipodium	1	CTNNB1
ruffle membrane	1	EGFR
Early endosome membrane	2	EGFR, WNT3A
Golgi apparatus membrane	1	GORASP1
Synapse	1	CTNNB1
cell cortex	1	CTNNB1
cell junction	3	CTNNB1, EGFR, PDGFRA
cell surface	4	EGFR, ITGAM, THBS1, WNT3A
glutamatergic synapse	4	CASP3, CTNNB1, EGFR, WNT3A
Golgi apparatus	2	GORASP1, PDGFRA
Golgi membrane	2	EGFR, GORASP1
growth cone	1	ANG
lysosomal membrane	1	EGF
neuronal cell body	2	ANG, CASP3
presynaptic membrane	1	CTNNB1
sarcolemma	1	ANXA5
Cytoplasm, cytosol	1	CASP7
Presynapse	1	WNT3A
endosome	1	EGFR
plasma membrane	6	CTNNB1, EGF, EGFR, ITGAM, PDGFRA, WNT3A
Membrane	8	ANXA5, CTNNB1, EGF, EGFR, HMOX1, ITGAM, NRK, PDGFRA
apical plasma membrane	1	EGFR
basolateral plasma membrane	2	CTNNB1, EGFR
caveola	1	PTGS2
extracellular exosome	7	ANXA5, CTNNB1, EGF, H2AX, ITGAM, THBS1, WNT3A
endoplasmic reticulum	3	HMOX1, PTGS2, THBS1
extracellular space	11	ANG, CASP7, CCL2, CHEK1, EGF, EGFR, HMOX1, ITGAM, MSMP, THBS1, WNT3A
perinuclear region of cytoplasm	3	CTNNB1, EGFR, HMOX1
Schaffer collateral - CA1 synapse	1	CTNNB1
adherens junction	1	CTNNB1
apicolateral plasma membrane	1	CTNNB1
bicellular tight junction	1	CTNNB1
protein-containing complex	6	CHEK1, CTNNB1, EGFR, HIF1A, PDGFRA, PTGS2
intracellular membrane-bounded organelle	1	CHEK1
Microsome membrane	1	PTGS2
postsynaptic density	1	CASP3
Single-pass type I membrane protein	3	EGFR, ITGAM, PDGFRA
Secreted	5	ANG, CCL2, MSMP, THBS1, WNT3A
extracellular region	6	ANG, ANXA5, CCL2, EGF, THBS1, WNT3A
mitochondrial outer membrane	1	HMOX1
transcription regulator complex	1	CTNNB1
Cell projection, cilium	1	PDGFRA
motile cilium	1	HIF1A
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome	1	CHEK1
nuclear membrane	1	EGFR
external side of plasma membrane	4	ANXA5, ITGAM, PDGFRA, THBS1
Secreted, extracellular space, extracellular matrix	2	THBS1, WNT3A
actin cytoskeleton	1	ANG
Z disc	1	CTNNB1
beta-catenin destruction complex	1	CTNNB1
nucleolus	1	ANG
Wnt signalosome	1	CTNNB1
axon cytoplasm	1	HIF1A
apical part of cell	1	CTNNB1
cell-cell junction	1	CTNNB1
postsynaptic membrane	1	CTNNB1
Membrane raft	2	EGFR, ITGAM
Cytoplasm, cytoskeleton	1	CTNNB1
focal adhesion	3	ANXA5, CTNNB1, EGFR
cis-Golgi network	1	GORASP1
Cell junction, adherens junction	1	CTNNB1
flotillin complex	1	CTNNB1
extracellular matrix	1	THBS1
basement membrane	1	ANG
intracellular vesicle	1	EGFR
sarcoplasmic reticulum	1	THBS1
collagen-containing extracellular matrix	2	ANXA5, THBS1
secretory granule	1	THBS1
fascia adherens	1	CTNNB1
lateral plasma membrane	1	CTNNB1
nuclear speck	2	H2AX, HIF1A
Nucleus inner membrane	1	PTGS2
Nucleus outer membrane	1	PTGS2
nuclear inner membrane	1	PTGS2
nuclear outer membrane	1	PTGS2
receptor complex	2	EGFR, PDGFRA
Zymogen granule membrane	1	ANXA5
neuron projection	1	PTGS2
cilium	1	PDGFRA
chromatin	2	CHEK1, HIF1A
cell periphery	1	CTNNB1
Chromosome	3	ANG, CHEK1, H2AX
Cytoplasm, cytoskeleton, cilium basal body	1	CTNNB1
Secreted, extracellular space	1	CASP7
Nucleus, nucleolus	1	ANG
spindle pole	1	CTNNB1
postsynaptic density, intracellular component	1	CTNNB1
microvillus membrane	1	CTNNB1
site of double-strand break	1	H2AX
Endomembrane system	1	CTNNB1
microvillus	1	PDGFRA
specific granule membrane	1	ITGAM
tertiary granule membrane	1	ITGAM
Cytoplasm, Stress granule	1	ANG
cytoplasmic stress granule	1	ANG
Nucleus speckle	1	HIF1A
euchromatin	2	CTNNB1, HIF1A
replication fork	2	CHEK1, H2AX
basal plasma membrane	1	EGFR
synaptic membrane	1	EGFR
platelet alpha granule	1	THBS1
plasma membrane raft	1	ITGAM
Golgi lumen	1	WNT3A
endoplasmic reticulum lumen	3	PTGS2, THBS1, WNT3A
male germ cell nucleus	1	H2AX
platelet alpha granule lumen	2	EGF, THBS1
endocytic vesicle membrane	1	WNT3A
XY body	1	H2AX
endocytic vesicle	1	ANG
beta-catenin-TCF complex	1	CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane	1	GORASP1
Golgi apparatus, cis-Golgi network membrane	1	GORASP1
Single-pass type IV membrane protein	1	HMOX1
condensed nuclear chromosome	2	CHEK1, H2AX
presynaptic active zone cytoplasmic component	1	CTNNB1
vesicle membrane	1	ANXA5
clathrin-coated endocytic vesicle membrane	2	EGF, EGFR
protein-DNA complex	1	CTNNB1
death-inducing signaling complex	1	CASP3
nucleosome	1	H2AX
catenin complex	1	CTNNB1
Wnt-Frizzled-LRP5/6 complex	1	WNT3A
site of DNA damage	1	H2AX
integrin complex	1	ITGAM
multivesicular body, internal vesicle lumen	1	EGFR
Shc-EGFR complex	1	EGFR
fibrinogen complex	1	THBS1
angiogenin-PRI complex	1	ANG
integrin alphaM-beta2 complex	1	ITGAM
endothelial microparticle	1	ANXA5
beta-catenin-TCF7L2 complex	1	CTNNB1
beta-catenin-ICAT complex	1	CTNNB1
Scrib-APC-beta-catenin complex	1	CTNNB1

文献列表

Florian Funk, Katharina Krüger, Christian Henninger, Wim Wätjen, Peter Proksch, Jürgen Thomale, Gerhard Fritz. Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity. Anti-cancer drugs. 2014 Sep; 25(8):917-29. doi: 10.1097/cad.0000000000000119. [PMID: 24820908]