Tomentosin (BioDeep_00000001040)

   

PANOMIX_OTCML-2023


代谢物信息卡片


2H-Cyclohepta(b)furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-(3-oxobutyl)-, (3aR,7S,8aR)-

化学式: C15H20O3 (248.14123700000002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1C(=O)OC2CC(C)C(CCC(C)=O)=CCC12
InChI: InChI=1S/C15H20O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h6,9,13-14H,3-5,7-8H2,1-2H3/t9-,13+,14+/m0/s1

描述信息

Tomentosin is a sesquiterpene lactone.
Tomentosin is a natural product found in Apalochlamys spectabilis, Leucophyta brownii, and other organisms with data available.

同义名列表

12 个代谢物同义名

2H-Cyclohepta(b)furan-2-one, 3,3a,4,7,8,8a-hexahydro-7-methyl-3-methylene-6-(3-oxobutyl)-, (3aR,7S,8aR)-; 7-Methyl-3-methylidene-6-(3-oxobutyl)-3,3a,4,7,8,8a-hexahydro-2H-cyclohepta[b]furan-2-one; 6-Deacetoxybritanlin G; Xanthalongi; Tomentosin; (3aR,7S,8aR)-7-methyl-3-methylidene-6-(3-oxobutyl)-4,7,8,8a-tetrahydro-3aH-cyclohepta[d]furan-2-one; (3aR,7S,8aR)-6-(3-ketobutyl)-7-methyl-3-methylene-4,7,8,8a-tetrahydro-3aH-cyclohepta[d]furan-2-one; (3aR,7S,8aR)-7-methyl-3-methylene-6-(3-oxobutyl)-4,7,8,8a-tetrahydro-3aH-cyclohepta[d]furan-2-one; 68736-88-9; 33649-15-9; C09562; Parthenium



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

55 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yu-Xi Di, Yu-Jie Bao, Zhi-Qi Zhu, Shan-Liang Sun, Feng-Xiang Tian, Fu-Rong Wang, Ge Yu, Ming-Fei Zhang, Jing Han, Ling-Ling Zhou. Tomentosin suppressed M1 polarization via increasing MERTK activation mediated by regulation of GAS6. Journal of ethnopharmacology. 2023 Apr; ?(?):116429. doi: 10.1016/j.jep.2023.116429. [PMID: 37011736]
  • Tuba Aydin, Ruya Saglamtas, Busra Dogan, Evin Kostekci, Rukiye Durmus, Ahmet Cakir. A new specific method for isolation of tomentosin with a high yield from Inula viscosa (L.) and determination of its bioactivities. Phytochemical analysis : PCA. 2022 Jun; 33(4):612-618. doi: 10.1002/pca.3114. [PMID: 35243708]
  • Yunhu Fan, M Maghimaa, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Sardar Hussain, Thamaraiselvan Rengarajan. Tomentosin Reduces Behavior Deficits and Neuroinflammatory Response in MPTP-Induced Parkinson's Disease in Mice. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2021; 40(1):75-84. doi: 10.1615/jenvironpatholtoxicoloncol.v40.i1.70. [PMID: 33639075]
  • Qinghao Jin, Jin Woo Lee, Hari Jang, Ji Eun Choi, Dongho Lee, Jin Tae Hong, Youngsoo Kim, Mi Kyeong Lee, Bang Yeon Hwang. Sesquiterpenes from Inula japonica with Inhibitory Effects on Nitric Oxide Production in Murine Macrophage RAW 264.7 Cells. Journal of natural products. 2016 06; 79(6):1548-53. doi: 10.1021/acs.jnatprod.5b01106. [PMID: 27276091]
  • Lin-fen Ding, Kou Wang, Hai-yin Wang, Wen-chao Tu, Zhen-tao Deng, Yue Zhou, Liu-dong Song. [Chemical Constituents of Inula japonica]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2016 Jun; 39(6):1296-9. doi: . [PMID: 30156801]
  • Chunfeng Xie, Lingmei Sun, Linghao Meng, Meicheng Wang, Jing Xu, Mark Bartlam, Yuanqiang Guo. Sesquiterpenes from Carpesium macrocephalum inhibit Candida albicans biofilm formation and dimorphism. Bioorganic & medicinal chemistry letters. 2015 Nov; 25(22):5409-11. doi: 10.1016/j.bmcl.2015.09.013. [PMID: 26394911]
  • Mette G Hyldgaard, Stig Purup, Andrew D Bond, Xavier C Fretté, Haiyan Qu, Katrine T Jensen, Lars P Christensen. Guaianolides and a seco-Eudesmane from the Resinous Exudates of Cushion Bush (Leucophyta brownii) and Evaluation of Their Cytostatic and Anti-inflammatory Activity. Journal of natural products. 2015 Aug; 78(8):1877-85. doi: 10.1021/acs.jnatprod.5b00208. [PMID: 26218649]
  • Xiangrong Cheng, Qi Zeng, Jie Ren, Jiangjiang Qin, Shoude Zhang, Yunheng Shen, Jiaxian Zhu, Fei Zhang, Ruijie Chang, Yan Zhu, Weidong Zhang, Huizi Jin. Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents. European journal of medicinal chemistry. 2011 Nov; 46(11):5408-15. doi: 10.1016/j.ejmech.2011.08.047. [PMID: 21924800]
  • Xu-Wen Li, Liang Weng, Xue Gao, Yun Zhao, Fei Pang, Jian-Hui Liu, Hong-Feng Zhang, Jin-Feng Hu. Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi. Bioorganic & medicinal chemistry letters. 2011 Jan; 21(1):366-72. doi: 10.1016/j.bmcl.2010.10.138. [PMID: 21109433]
  • Sharon Rozenblat, Shlomo Grossman, Margalit Bergman, Hugo Gottlieb, Yigal Cohen, Sara Dovrat. Induction of G2/M arrest and apoptosis by sesquiterpene lactones in human melanoma cell lines. Biochemical pharmacology. 2008 Jan; 75(2):369-82. doi: 10.1016/j.bcp.2007.08.024. [PMID: 17919456]
  • C Cafarchia, N De Laurentis, M A Milillo, V Losacco, V Puccini. [Fungistatic activity of a sesquiterpene lactone (tomentosin) isolated from fresh Inula viscosa (Asteraceae) flowers from the Puglia region]. Parassitologia. 2001 Sep; 43(3):117-21. doi: ". [PMID: 11921538]