Sirodesmin H (BioDeep_00000008207)

   

natural product


Metabolite Card


Sirodesmin H

Formula: C20H26N2O8S (454.141)
Chinese Names:
Spectrum Hits: Top Source () 0%

Molecular Structure

SMILES: CC(=O)OC1C2(CC3N4C(=O)C5(CO)SC4(CC31O)C(=O)N5C)OC(C)C(C)(C)C2=O
InChI: InChI=1S/C20H26N2O8S/c1-9-16(3,4)12(25)18(30-9)6-11-17(28,13(18)29-10(2)24)7-19-14(26)21(5)20(8-23,31-19)15(27)22(11)19/h9,11,13,23,28H,6-8H2,1-5H3/t9-,11-,13+,17+,18-,19-,20-/m1/s1

Description

Synonyms

2 synonym names

Sirodesmin H; Sirodesmin H



Cross Reference

15 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

Sub-cellular location Genes


Literature Reference

  • James A Fortune, Evren Bingol, Aiming Qi, Daniel Baker, Faye Ritchie, Chinthani S Karandeni Dewage, Bruce D L Fitt, Yong-Ju Huang. Leptosphaeria biglobosa inhibits the production of sirodesmin PL by L. maculans. Pest management science. 2024 May; 80(5):2416-2425. doi: 10.1002/ps.7275. [PMID: 36327145]
  • Andrew S Urquhart, Candace E Elliott, Wei Zeng, Alexander Idnurm. Constitutive expression of transcription factor SirZ blocks pathogenicity in Leptosphaeria maculans independently of sirodesmin production. PloS one. 2021; 16(6):e0252333. doi: 10.1371/journal.pone.0252333. [PMID: 34111151]
  • M Soledade C Pedras, Iman Khallaf. Molecular interactions of the phytotoxins destruxin B and sirodesmin PL with crucifers and cereals: metabolism and elicitation of plant defenses. Phytochemistry. 2012 May; 77(?):129-39. doi: 10.1016/j.phytochem.2012.02.010. [PMID: 22414311]
  • Candace E Elliott, Ellen M Fox, Renee S Jarvis, Barbara J Howlett. The cross-pathway control system regulates production of the secondary metabolite toxin, sirodesmin PL, in the ascomycete, Leptosphaeria maculans. BMC microbiology. 2011 Jul; 11(?):169. doi: 10.1186/1471-2180-11-169. [PMID: 21791055]
  • M Soledade C Pedras, Yang Yu. Stress-driven discovery of metabolites from the phytopathogenic fungus Leptosphaeria maculans: structure and activity of leptomaculins A-E. Bioorganic & medicinal chemistry. 2008 Sep; 16(17):8063-71. doi: 10.1016/j.bmc.2008.07.060. [PMID: 18701303]
  • Ellen M Fox, Donald M Gardiner, Nancy P Keller, Barbara J Howlett. A Zn(II)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans. Fungal genetics and biology : FG & B. 2008 May; 45(5):671-82. doi: 10.1016/j.fgb.2007.10.005. [PMID: 18023597]
  • Donald M Gardiner, Anton J Cozijnsen, Leanne M Wilson, M Soledade C Pedras, Barbara J Howlett. The sirodesmin biosynthetic gene cluster of the plant pathogenic fungus Leptosphaeria maculans. Molecular microbiology. 2004 Sep; 53(5):1307-18. doi: 10.1111/j.1365-2958.2004.04215.x. [PMID: 15387811]
  • B J Howlett, A Idnurm, M S Pedras. Leptosphaeria maculans, the causal agent of blackleg disease of Brassicas. Fungal genetics and biology : FG & B. 2001 Jun; 33(1):1-14. doi: 10.1006/fgbi.2001.1274. [PMID: 11407881]
  • K Voigt, M Jedryczka, J Wöstemeyer. Strain typing of polish Leptosphaeria maculans isolates supports at the genomic level the multi-species concept of aggressive and non-aggressive strains. Microbiological research. 2001; 156(2):169-77. doi: 10.1078/0944-5013-00099. [PMID: 11572457]
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