(±)-Mellein (BioDeep_00000624878)

   

natural product


代谢物信息卡片


(3R)-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one

化学式: C10H10O3 (178.063)
中文名称: 蜂蜜曲菌素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2=C(C(=CC=C2)O)C(=O)O1
InChI: InChI=1S/C10H10O3/c1-6-5-7-3-2-4-8(11)9(7)10(12)13-6/h2-4,6,11H,5H2,1H3/t6-/m1/s1

描述信息

D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins

同义名列表

3 个代谢物同义名

(3R)-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one; (±)-Mellein; (R)-(-)-Mellein



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

90 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • M Saraswathi, S H Meshram, B Siva, S Misra, K Suresh Babu. Isolation, purification and structural elucidation of Mellein from endophytic fungus Lasiodiplodia theobromae strain (SJF-1) and its broad-spectrum antimicrobial and pharmacological properties. Letters in applied microbiology. 2022 Dec; 75(6):1475-1485. doi: 10.1111/lam.13813. [PMID: 36000410]
  • Yuanze Li, Zheng Gai, Caixia Wang, Pingliang Li, Baohua Li. Identification of Mellein as a Pathogenic Substance of Botryosphaeria dothidea by UPLC-MS/MS Analysis and Phytotoxic Bioassay. Journal of agricultural and food chemistry. 2021 Aug; 69(30):8471-8481. doi: 10.1021/acs.jafc.1c03249. [PMID: 34304561]
  • Marco Masi, Pierluigi Reveglia, Regina Baaijens-Billones, Marcin Górecki, Gennaro Pescitelli, Sandra Savocchia, Antonio Evidente. Phytotoxic Metabolites from Three Neofusicoccum Species Causal Agents of Botryosphaeria Dieback in Australia, Luteopyroxin, Neoanthraquinone, and Luteoxepinone, a Disubstituted Furo-α-pyrone, a Hexasubstituted Anthraquinone, and a Trisubstituted Oxepi-2-one from Neofusicoccum luteum. Journal of natural products. 2020 02; 83(2):453-460. doi: 10.1021/acs.jnatprod.9b01057. [PMID: 31951128]
  • Chao Huang, Juan Xiong, Hui-Da Guan, Chang-Hong Wang, Xinsheng Lei, Jin-Feng Hu. Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors. Bioorganic & medicinal chemistry. 2019 05; 27(10):2027-2040. doi: 10.1016/j.bmc.2019.03.060. [PMID: 30975503]
  • Alessio Cimmino, Tamara Cinelli, Marco Masi, Pierluigi Reveglia, Marcondes Araujo da Silva, Laura Mugnai, Sami J Michereff, Giuseppe Surico, Antonio Evidente. Phytotoxic Lipophilic Metabolites Produced by Grapevine Strains of Lasiodiplodia Species in Brazil. Journal of agricultural and food chemistry. 2017 Feb; 65(6):1102-1107. doi: 10.1021/acs.jafc.6b04906. [PMID: 28110532]
  • Suwaibah Madmanang, Naseebah Cheyeng, Sareefah Heembenmad, Wilawan Mahabusarakam, Jongkon Saising, Markus Seeger, Sasitorn Chusri, Suda Chakthong. Constituents of Fagraea fragrans with Antimycobacterial Activity in Combination with Erythromycin. Journal of natural products. 2016 Apr; 79(4):767-74. doi: 10.1021/acs.jnatprod.5b00691. [PMID: 26905094]
  • Yit-Heng Chooi, Christian Krill, Russell A Barrow, Shasha Chen, Robert Trengove, Richard P Oliver, Peter S Solomon. An in planta-expressed polyketide synthase produces (R)-mellein in the wheat pathogen Parastagonospora nodorum. Applied and environmental microbiology. 2015 Jan; 81(1):177-86. doi: 10.1128/aem.02745-14. [PMID: 25326302]
  • M Ramírez-Suero, M Bénard-Gellon, J Chong, H Laloue, E Stempien, E Abou-Mansour, F Fontaine, P Larignon, F Mazet-Kieffer, S Farine, C Bertsch. Extracellular compounds produced by fungi associated with Botryosphaeria dieback induce differential defence gene expression patterns and necrosis in Vitis vinifera cv. Chardonnay cells. Protoplasma. 2014 Nov; 251(6):1417-26. doi: 10.1007/s00709-014-0643-y. [PMID: 24752796]
  • Jiaying Wang, Guoping Wang, Yalei Zhang, Biqiang Zheng, Chulong Zhang, Liwei Wang. Isolation and identification of an endophytic fungus Pezicula sp. in Forsythia viridissima and its secondary metabolites. World journal of microbiology & biotechnology. 2014 Oct; 30(10):2639-44. doi: 10.1007/s11274-014-1686-0. [PMID: 24928260]
  • Mark W Sumarah, Eva Puniani, Barbara A Blackwell, J David Miller. Characterization of polyketide metabolites from foliar endophytes of Picea glauca. Journal of natural products. 2008 Aug; 71(8):1393-8. doi: 10.1021/np800192f. [PMID: 18636777]