Thapsigargin (BioDeep_00000000710)

   

PANOMIX_OTCML-2023 Chemicals and Drugs natural product Volatile Flavor Compounds


代谢物信息卡片


[(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-acetyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-[(Z)-2-methylbut-2-enoyl]oxy-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] octanoate

化学式: C34H50O12 (650.33021)
中文名称: 毒胡萝卜素, 毒胡萝卜内酯
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 12.12%

Reviewed

Last reviewed on 2024-11-06.

Cite this Page

Thapsigargin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/thapsigargin (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000000710). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C/C=C(/C)C(=O)O[C@H]1C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@@H](OC(=O)CCC)C[C@](C)(OC(C)=O)[C@H]2[C@@H]1OC(=O)CCCCCCC
InChI: InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1

描述信息

Thapsigargin is an organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. It has a role as an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a calcium channel blocker. It is a sesquiterpene lactone, an organic heterotricyclic compound and a butyrate ester.
Thapsigargin is a natural product found in Thapsia gymnesica, Thapsia villosa, and Thapsia garganica with data available.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
C1907 - Drug, Natural Product > C28269 - Phytochemical > C93252 - Sesquiterpene Lactone
D004791 - Enzyme Inhibitors

(-)-Thapsigargin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=67526-95-8 (retrieved 2024-11-06) (CAS RN: 67526-95-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

35 个代谢物同义名

OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER; OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OXY]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER; Octanoic Acid [3s-[3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha(Z), 9balpha]]-6-(Acetyloxy)-2,3,-3a,4,5,6,6a,7,8,9b-Decahydro-3,3a-Dihydroxy-3,6,9-Trimethyl-8-[(2-Methyl-1-Oxo-2-Butenyl)oxy]-2-Oxo-4-(1-Oxobutoxy)-Azuleno[4,5-B]furan-7-Yl Ester; Octanoic Acid [3s-[3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha(Z), 9balpha]]-6-(Acetyloxy)-2,3,-3a,4,5,6,6a,7,8,9b-Decahydro-3,3a-Dihydroxy-3,6,9-Trimethyl-8-[(2-Methyl-1-Oxo-2-Butenyl)oxy]-2-Oxo-4-(1-Oxobutoxy)-Azuleno[4,5-B]furan-7-Yl Ester; Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-((2-methyl-1-oxo-2-butenyl)oxy)-2-oxo-4-(1-oxobutoxy)azuleno(4,5-b)furan-7-yl ester, (3S-(3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha))-; octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester; OCTANOIC ACID, (3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-(((2Z)-2-METHYL-1-OXO-2-BUTEN-1-YL)OXY)-2-OXO-4-(1-OXOBUTOXY)AZULENO(4,5-B)FURAN-7-YL ESTER; (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b- decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate; (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]f uran-7-yl ester; (3S,3aR,4S,6S,6AR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate; Octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]fura; Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester, [3S-[3alpha,3abeta,4; octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(-oxobutoxy)azuleno[4,5-b]furan; (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2H,3H,3aH,4H,5H,6H,6aH,7H,8H,9bH-azuleno[4,5-b]furan-7-yl octanoate; (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate; 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX; OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z),; Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER; alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]]-; Azuleno[4,5-b]furan, octanoic acid deriv.; Thapsigargin, >=98\\% (HPLC), solid film; n-7-yl ester (9CI); THAPSIGARGIN [MI]; (-)-Thapsigargin; UNII-Z96BQ26RZD; Lopac0_001262; Tox21_501262; Thapsigargin; IDI1_033971; -7-yl ester; Z96BQ26RZD; C34H50O12; TG1; octanoic acid [6-acetyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-(2-methyl-1-oxobut-2-enoxy)-2-oxo-4-(1-oxobutoxy)-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] ester; Thapsigargin



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Abeer Al Otaibi, Sindiyan Al Shaikh Mubarak, Fatimah Al Hejji, Abdulrahman Almasaud, Haya Al Jami, Jahangir Iqbal, Ali Al Qarni, Naif Khalaf Al Harbi, Ahmed Bakillah. Thapsigargin and Tunicamycin Block SARS-CoV-2 Entry into Host Cells via Differential Modulation of Unfolded Protein Response (UPR), AKT Signaling, and Apoptosis. Cells. 2024 Apr; 13(9):. doi: 10.3390/cells13090769. [PMID: 38727305]
  • Huan Zhang, Chao Yang, Songjiao Wang, Aohong Xu, Qian Zhang, Xiuqun Duan, Guofu Gong, Yuxue Wang. Overexpression of salusin‑α upregulates AdipoR2 and activates the PPARα/ApoA5/SREBP‑1c pathway to inhibit lipid synthesis in HepG2 cells. International journal of molecular medicine. 2023 May; 51(5):. doi: 10.3892/ijmm.2023.5244. [PMID: 37026514]
  • Maria H Jäntti, Shelley N Jackson, Jeffrey Kuhn, Ilmari Parkkinen, Sreesha Sree, Joshua J Hinkle, Eija Jokitalo, Leesa J Deterding, Brandon K Harvey. Palmitate and thapsigargin have contrasting effects on ER membrane lipid composition and ER proteostasis in neuronal cells. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2022 11; 1867(11):159219. doi: 10.1016/j.bbalip.2022.159219. [PMID: 35981704]
  • Mohammed Samer Shaban, Christin Mayr-Buro, Johanna Meier-Soelch, Benadict Vincent Albert, M Lienhard Schmitz, John Ziebuhr, Michael Kracht. Thapsigargin: key to new host-directed coronavirus antivirals?. Trends in pharmacological sciences. 2022 Jul; 43(7):557-568. doi: 10.1016/j.tips.2022.04.004. [PMID: 35534355]
  • Hassan O J Morad, Suaib Luqman, Larissa Garcia Pinto, Kevin P Cunningham, Bruno Vilar, Georgia Clayton, Manu Shankar-Hari, Peter A McNaughton. Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release. Scientific reports. 2022 06; 12(1):11078. doi: 10.1038/s41598-022-15214-6. [PMID: 35773325]
  • Atousa Khalatbari, Zahra Aghazadeh, Cheng Ji. Adverse Effects of Anti-Covid-19 Drug Candidates and Alcohol on Cellular Stress Responses of Hepatocytes. Hepatology communications. 2022 06; 6(6):1262-1277. doi: 10.1002/hep4.1887. [PMID: 34910385]
  • Duygu Elif Yilmaz, Karin Kirschner, Hasan Demirci, Nina Himmerkus, Sebastian Bachmann, Kerim Mutig. Immunosuppressive calcineurin inhibitor cyclosporine A induces proapoptotic endoplasmic reticulum stress in renal tubular cells. The Journal of biological chemistry. 2022 03; 298(3):101589. doi: 10.1016/j.jbc.2022.101589. [PMID: 35033536]
  • Eric D Deihl, Luke T Jesikiewicz, Logan J Newman, Peng Liu, Kay M Brummond. Rh(I)-Catalyzed Allenic Pauson-Khand Reaction to Access the Thapsigargin Core: Influence of Furan and Allenyl Chloroacetate Groups on Enantioselectivity. Organic letters. 2022 02; 24(4):995-999. doi: 10.1021/acs.orglett.1c03951. [PMID: 35081313]
  • Wing-Kee Lee, Michelle Maaß, Amy Quach, Nataliya Poscic, Holly Prangley, Erin-Claire Pallott, Jiyoon L Kim, Jason S Pierce, Besim Ogretmen, Anthony H Futerman, Frank Thévenod. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. The Journal of biological chemistry. 2022 02; 298(2):101492. doi: 10.1016/j.jbc.2021.101492. [PMID: 34915026]
  • Min Yao, Gan Li, Long-Yun Zhou, Zhong Zheng, Yue-Li Sun, Shu-Fen Liu, Yong-Jun Wang, Xue-Jun Cui. Shikonin inhibits neuronal apoptosis via regulating endoplasmic reticulum stress in the rat model of double-level chronic cervical cord compression. Cell biology and toxicology. 2022 Jan; ?(?):. doi: 10.1007/s10565-021-09648-3. [PMID: 35028790]
  • Sarah Al-Beltagi, Leah V Goulding, Daniel K E Chang, Kenneth H Mellits, Christopher J Hayes, Pavel Gershkovich, Christopher M Coleman, Kin-Chow Chang. Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin. Virulence. 2021 12; 12(1):2946-2956. doi: 10.1080/21505594.2021.2006960. [PMID: 34793280]
  • Kazuhiro Ogi, Tetsuji Takabayashi, Kaori Tomita, Masafumi Sakashita, Taiyo Morikawa, Takahiro Ninomiya, Masayuki Okamoto, Norihiko Narita, Shigeharu Fujieda. ORMDL3 overexpression facilitates FcεRI-mediated transcription of proinflammatory cytokines and thapsigargin-mediated PERK phosphorylation in RBL-2H3 cells. Immunity, inflammation and disease. 2021 12; 9(4):1394-1405. doi: 10.1002/iid3.489. [PMID: 34288557]
  • Anqi Kong, Yao Zhang, Bo Ning, Kongdong Li, Zhen Ren, Shuya Dai, Dongfeng Chen, Yang Zhou, Jie Gu, Haifeng Shi. Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis. Chemico-biological interactions. 2021 Oct; 348(?):109649. doi: 10.1016/j.cbi.2021.109649. [PMID: 34516972]
  • Mohammed Samer Shaban, Christin Müller, Christin Mayr-Buro, Hendrik Weiser, Johanna Meier-Soelch, Benadict Vincent Albert, Axel Weber, Uwe Linne, Torsten Hain, Ilya Babayev, Nadja Karl, Nina Hofmann, Stephan Becker, Susanne Herold, M Lienhard Schmitz, John Ziebuhr, Michael Kracht. Multi-level inhibition of coronavirus replication by chemical ER stress. Nature communications. 2021 09; 12(1):5536. doi: 10.1038/s41467-021-25551-1. [PMID: 34545074]
  • Simon Ngao Mule, Vinícius De Morais Gomes, Rosangela A M Wailemann, Janaina Macedo-da-Silva, Livia Rosa-Fernandes, Martin R Larsen, Letícia Labriola, Giuseppe Palmisano. HSPB1 influences mitochondrial respiration in ER-stressed beta cells. Biochimica et biophysica acta. Proteins and proteomics. 2021 09; 1869(9):140680. doi: 10.1016/j.bbapap.2021.140680. [PMID: 34051341]
  • Nanami Goto, Shusaku Shibutani, Noboru Miura, Rie Watanabe, Hiroyuki Iwata. Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress. Biochemical and biophysical research communications. 2021 05; 552(?):30-36. doi: 10.1016/j.bbrc.2021.03.017. [PMID: 33740662]
  • Chinmayee Das, Manoj K Rout, Willem C Wildering, Mathilakath M Vijayan. Cortisol modulates calcium release-activated calcium channel gating in fish hepatocytes. Scientific reports. 2021 05; 11(1):9621. doi: 10.1038/s41598-021-88957-3. [PMID: 33953236]
  • Jung Woo Han, Woon Heo, Donghyuk Lee, Choeun Kang, Hye-Yeon Kim, Ikhyun Jun, Insuk So, Hyuk Hur, Min Goo Lee, Minkyu Jung, Joo Young Kim. Plasma Membrane Localized GCaMP-MS4A12 by Orai1 Co-Expression Shows Thapsigargin- and Ca2+-Dependent Fluorescence Increases. Molecules and cells. 2021 Apr; 44(4):223-232. doi: 10.14348/molcells.2021.2031. [PMID: 33935043]
  • Pavla Taborska, Dmitry Stakheev, Jirina Bartunkova, Daniel Smrz. Thapsigargin-Stimulated LAD2 Human Mast Cell Line Is a Potent Cellular Adjuvant for the Maturation of Monocyte-Derived Dendritic Cells for Adoptive Cellular Immunotherapy. International journal of molecular sciences. 2021 Apr; 22(8):. doi: 10.3390/ijms22083978. [PMID: 33921475]
  • Julien Allard, Simon Bucher, Julie Massart, Pierre-Jean Ferron, Dounia Le Guillou, Roxane Loyant, Yoann Daniel, Youenn Launay, Nelly Buron, Karima Begriche, Annie Borgne-Sanchez, Bernard Fromenty. Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell biology and toxicology. 2021 04; 37(2):151-175. doi: 10.1007/s10565-020-09537-1. [PMID: 32535746]
  • Sarah Al-Beltagi, Cristian Alexandru Preda, Leah V Goulding, Joe James, Juan Pu, Paul Skinner, Zhimin Jiang, Belinda Lei Wang, Jiayun Yang, Ashley C Banyard, Kenneth H Mellits, Pavel Gershkovich, Christopher J Hayes, Jonathan Nguyen-Van-Tam, Ian H Brown, Jinhua Liu, Kin-Chow Chang. Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus. Viruses. 2021 02; 13(2):. doi: 10.3390/v13020234. [PMID: 33546185]
  • Søren Brøgger Christensen, Henrik Toft Simonsen, Nikolai Engedal, Poul Nissen, Jesper Vuust Møller, Samuel R Denmeade, John T Isaacs. From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development. Progress in the chemistry of organic natural products. 2021; 115(?):59-114. doi: 10.1007/978-3-030-64853-4_2. [PMID: 33797641]
  • Noemi Esteras, Franziska Kundel, Giuseppe F Amodeo, Evgeny V Pavlov, David Klenerman, Andrey Y Abramov. Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase. The FEBS journal. 2021 01; 288(1):127-141. doi: 10.1111/febs.15340. [PMID: 32338825]
  • Yulin Ren, A Douglas Kinghorn. Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones. Journal of medicinal chemistry. 2020 12; 63(24):15410-15448. doi: 10.1021/acs.jmedchem.0c01449. [PMID: 33289552]
  • Tomáš Zimmermann, Pavel Drašar, Silvie Rimpelová, Søren Brøgger Christensen, Vladimir A Khripach, Michal Jurášek. Large Scale Conversion of Trilobolide into the Payload of Mipsagargin: 8-O-(12-Aminododecanoyl)-8-O-Debutanoylthapsigargin. Biomolecules. 2020 12; 10(12):. doi: 10.3390/biom10121640. [PMID: 33291419]
  • A G Gomes Coutinho, E Pinheiro, R Fernandez. The calcium sensing receptor modulates H+-ATPase activity in intercalated cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2020 Dec; 71(6):. doi: 10.26402/jpp.2020.6.09. [PMID: 33901996]
  • Yohan Bignon, Virginie Poindessous, Luca Rampoldi, Violette Haldys, Nicolas Pallet. Chemically based transmissible ER stress protocols are unsuitable to study cell-to-cell UPR transmission. The Biochemical journal. 2020 10; 477(20):4037-4051. doi: 10.1042/bcj20200699. [PMID: 33016323]
  • Taiding Wu, Nina Yin, Xiaoyun Chen, Hao Huang, Yanhong Liao. Functional coupling between BKCa and SOC channels. Tissue & cell. 2020 Oct; 66(?):101394. doi: 10.1016/j.tice.2020.101394. [PMID: 32933717]
  • Kyung Hwan Jegal, Eun Ok Kim, Jae Kwang Kim, Sang Mi Park, Dae Hwa Jung, Gum Hwa Lee, Sung Hwan Ki, Sung Hui Byun, Sae Kwang Ku, Il Je Cho, Sang Chan Kim. Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction. Toxicology and applied pharmacology. 2020 07; 399(?):115036. doi: 10.1016/j.taap.2020.115036. [PMID: 32407927]
  • Eduard Sarró, Mónica Durán, Ana Rico, Diana Bou-Teen, Vanesa Fernández-Majada, Anthony J Croatt, Karl A Nath, Maria Teresa Salcedo, Justin H Gundelach, Daniel Batlle, Richard J Bram, Anna Meseguer. Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype. Journal of molecular cell biology. 2020 07; 12(7):499-514. doi: 10.1093/jmcb/mjaa005. [PMID: 32162654]
  • Rodrigo Aguayo-Ortiz, L Michel Espinoza-Fonseca. Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities. International journal of molecular sciences. 2020 Jun; 21(11):. doi: 10.3390/ijms21114146. [PMID: 32532023]
  • Hong-Ting Lu, Ren-Qian Feng, Jia-Kun Tang, Jing-Jun Zhou, Feng Gao, Jun Ren. CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts. Cell death & disease. 2020 05; 11(5):388. doi: 10.1038/s41419-020-2605-y. [PMID: 32439852]
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