P-Hydroxyphenylethanolamine (BioDeep_00000004096)

 

Secondary id: BioDeep_00001868514

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


alpha-(Aminoethyl)-4-hydroxybenzenemethanol

化学式: C8H11NO2 (153.0789746)
中文名称: 章胺, 章鱼胺, 对羟基苯乙醇胺, 奥克巴胺
谱图信息: 最多检出来源 Homo sapiens(blood) 0.22%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

P-Hydroxyphenylethanolamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/p-hydroxyphenylethanolamine (retrieved 2024-11-25) (BioDeep RN: BioDeep_00000004096). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CC=C1C(CN)O)O
InChI: InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2

描述信息

Alkaloid from leaves of tabasco pepper (Capsicum frutescens), nutgrass (Cyperus rotundus) and leaves or fruit of Citrus subspecies Occurs in many animal tissues; found in high concs. in octopus
p-Octopamine is an amine in traces quantities in plasma and cerebrospinal fluid in humans with septic encephalopathy (PMID 15932098).
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist

同义名列表

29 个代谢物同义名

alpha-(Aminoethyl)-4-hydroxybenzenemethanol; 4-[(1R)-2-amino-1-hydroxyethyl]phenol; 2-amino-1-(4-Hydroxyphenyl)ethanol; 1-(P-Hydroxyphenyl)-2-aminoethanol; 1-(4-Hydroxyphenyl)-2-aminoethanol; 4-(2R-AMINO-1-hydroxyethyl)phenol; 4-[2-amino-1-Hydroxyethyl]phenol; p-Hydroxyphenylethanolamine; 4-Hydroxyphenethanolamine; Racemic octopamine; (RS)-Octopamine; Para-octopamine; (R)-Octopamine; DL-Octopamine; Norsynephrine; 4-Octopamine; p-Octopamine; Norsympathol; Norsympatol; octopamine; Norphen; Norton; Analet; Norden; ND 50; Octopamine (p-Hydroxyphenylethanolamine); p-Octopamine; Octopamine; US10112926, Example 104.14



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shuhao Wang, Yang Li, Xin Lin, Xiangjin Fu, Haiyan Zhong, Kangzi Ren, Cheng Liu, Wen Yao. Rapid Screening of Phenolic Compounds with Anti-Enteritis Activity from Camellia oleifera Oil Using a Smurf Drosophila Model and Molecular Docking Methods. Molecules (Basel, Switzerland). 2023 Dec; 29(1):. doi: 10.3390/molecules29010076. [PMID: 38202658]
  • Ping Cai, Yuanyuan Zhang, Mu Yang, Chenghao Zhang, Mingxia Li, Wei Xiao, Zhifeng Xu, Yongqiang Zhang. Target identification and acaricidal activity difference of amitraz and its metabolite DPMF in Tetranychus cinnabarinus (Boisduval). Pest management science. 2023 Apr; ?(?):. doi: 10.1002/ps.7500. [PMID: 37036086]
  • Gang Xu, Yuan-Yuan Zhang, Gui-Xiang Gu, Guo-Qing Yang, Gong-Yin Ye. Molecular and Pharmacological Characterization of β-Adrenergic-like Octopamine Receptors in the Endoparasitoid Cotesia chilonis (Hymenoptera: Braconidae). International journal of molecular sciences. 2022 Nov; 23(23):. doi: 10.3390/ijms232314513. [PMID: 36498840]
  • Yue Yang, Xingyu Ma, Long Zhang, Wenli Zhao, Xiaoguang Liu, Xiang Li, Mengfang Du, Shiheng An. Octopamine terminates sex pheromone biosynthesis by suppressing PBAN signal in moths. Insect molecular biology. 2022 10; 31(5):647-658. doi: 10.1111/imb.12793. [PMID: 35652818]
  • Dandan Liu, Xinxin Zhang, Fang Chiqin, Innocent Nyamwasa, Yazhong Cao, Jiao Yin, Shuai Zhang, Honglin Feng, Kebin Li. Octopamine modulates insect mating and Oviposition. Journal of chemical ecology. 2022 Aug; 48(7-8):628-640. doi: 10.1007/s10886-022-01366-2. [PMID: 35687218]
  • Pantea Kianmehr, Mohammad Ali Azarbayjani, Maghsoud Peeri, Parvin Farzanegi. The effects of aerobic exercise training with octopamine supplementation on cardiomyocyte apoptosis induced by deep-frying oil: The role of caspase and procaspase 3. Clinical nutrition ESPEN. 2022 06; 49(?):529-535. doi: 10.1016/j.clnesp.2022.02.008. [PMID: 35623862]
  • Dahae Lee, Ji Hwan Lee, Byoung Ha Kim, Sanghyun Lee, Dong-Wook Kim, Ki Sung Kang. Phytochemical Combination (p-Synephrine, p-Octopamine Hydrochloride, and Hispidulin) for Improving Obesity in Obese Mice Induced by High-Fat Diet. Nutrients. 2022 May; 14(10):. doi: 10.3390/nu14102164. [PMID: 35631305]
  • Sheraz Ahmad, Yu Chen, Jieyu Zhang, David Stanley, Qisheng Song, Linquan Ge. Octopamine signaling is involved in the female postmating state in Nilaparvata lugens Stål (Hemiptera: Delphacidae). Archives of insect biochemistry and physiology. 2021 Aug; 107(4):e21825. doi: 10.1002/arch.21825. [PMID: 34164848]
  • Li-Sha Zheng, Xiao-Qiang Liu, Ge-Ge Liu, Qian-Qiao Huang, Jin-Jun Wang, Hong-Bo Jiang. Knockdown of a β-Adrenergic-Like Octopamine Receptor Affects Locomotion and Reproduction of Tribolium castaneum. International journal of molecular sciences. 2021 Jul; 22(14):. doi: 10.3390/ijms22147252. [PMID: 34298876]
  • Yicong Jia, Shan Jin, Kunkun Hu, Lei Geng, Caihong Han, Ruxue Kang, Yuxin Pang, Erjun Ling, Eng King Tan, Yufeng Pan, Wei Liu. Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature communications. 2021 05; 12(1):2698. doi: 10.1038/s41467-021-23041-y. [PMID: 33976215]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Zhangwu Zhao, Xianguo Zhao, Tao He, Xiaoyu Wu, Pengfei Lv, Alan J Zhu, Juan Du. Epigenetic regulator Stuxnet modulates octopamine effect on sleep through a Stuxnet-Polycomb-Octβ2R cascade. EMBO reports. 2021 02; 22(2):e47910. doi: 10.15252/embr.201947910. [PMID: 33410264]
  • Abisola Grace Ayanlowo, Zsófia Garádi, Imre Boldizsár, András Darcsi, Andrea Nagyné Nedves, Bence Varjas, Alexandra Simon, Ágnes Alberti, Eszter Riethmüller. UHPLC-DPPH method reveals antioxidant tyramine and octopamine derivatives in Celtis occidentalis. Journal of pharmaceutical and biomedical analysis. 2020 Nov; 191(?):113612. doi: 10.1016/j.jpba.2020.113612. [PMID: 32980795]
  • Mohamed Ahmed Ibrahim Ahmed, Christoph Franz Adam Vogel. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster. Chemosphere. 2020 Aug; 253(?):126629. doi: 10.1016/j.chemosphere.2020.126629. [PMID: 32283422]
  • Gang Xu, Xue-Fei Chang, Gui-Xiang Gu, Wen-Xi Jia, Lei Guo, Jia Huang, Gong-Yin Ye. Molecular and pharmacological characterization of a β-adrenergic-like octopamine receptor from the green rice leafhopper Nephotettix cincticeps. Insect biochemistry and molecular biology. 2020 05; 120(?):103337. doi: 10.1016/j.ibmb.2020.103337. [PMID: 32109588]
  • Vanessa Corby-Harris, Megan E Deeter, Lucy Snyder, Charlotte Meador, Ashley C Welchert, Amelia Hoffman, Bethany T Obernesser. Octopamine mobilizes lipids from honey bee (Apis mellifera) hypopharyngeal glands. The Journal of experimental biology. 2020 04; 223(Pt 8):. doi: 10.1242/jeb.216135. [PMID: 32139471]
  • Matthias Romauch. Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 3. Open biology. 2020 04; 10(4):190035. doi: 10.1098/rsob.190035. [PMID: 32315567]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Andy Hsien Wei Koh, Russ Chess-Williams, Anna Elizabeth Lohning. Differential mechanisms of action of the trace amines octopamine, synephrine and tyramine on the porcine coronary and mesenteric artery. Scientific reports. 2019 07; 9(1):10925. doi: 10.1038/s41598-019-46627-5. [PMID: 31358768]
  • Sandra Arancibia, Matías Marambio, Jorge M Campusano, Angélica Fierro. Modeling of the Binding of Octopamine and Dopamine in Insect Monoamine Transporters Reveals Structural and Electrostatic Differences. ACS chemical neuroscience. 2019 05; 10(5):2310-2317. doi: 10.1021/acschemneuro.8b00631. [PMID: 30605598]
  • Hsin-Wei Kuo, Dong-Wei Lin, Winton Cheng. Transient enhancement of immune resistance functions in Litopenaeus vannamei through a low-dose octopamine injection. Fish & shellfish immunology. 2019 Jan; 84(?):532-540. doi: 10.1016/j.fsi.2018.10.060. [PMID: 30366092]
  • Li Xu, Hong-Bo Jiang, Xiao-Feng Chen, Ying Xiong, Xue-Ping Lu, Yu-Xia Pei, Guy Smagghe, Jin-Jun Wang. How Tyramine β-Hydroxylase Controls the Production of Octopamine, Modulating the Mobility of Beetles. International journal of molecular sciences. 2018 Mar; 19(3):. doi: 10.3390/ijms19030846. [PMID: 29538302]
  • Hailong Kong, Chuanlei Dong, Zhen Tian, Nian Mao, Cheng Wang, Yunxia Cheng, Lei Zhang, Xingfu Jiang, Lizhi Luo. Altered immunity in crowded Mythimna separata is mediated by octopamine and dopamine. Scientific reports. 2018 02; 8(1):3215. doi: 10.1038/s41598-018-20711-8. [PMID: 29453438]
  • Ross E Beaumont, Philip Cordery, Lewis J James, Phillip Watson. Supplementation with a low-dose of octopamine does not influence endurance cycling performance in recreationally active men. Journal of science and medicine in sport. 2017 Oct; 20(10):952-956. doi: 10.1016/j.jsams.2017.03.007. [PMID: 28389217]
  • Shun-Fan Wu, Xiao-Min Jv, Jian Li, Guang-Jian Xu, Xiao-Yi Cai, Cong-Fen Gao. Pharmacological characterisation and functional roles for egg-laying of a β-adrenergic-like octopamine receptor in the brown planthopper Nilaparvata lugens. Insect biochemistry and molecular biology. 2017 08; 87(?):55-64. doi: 10.1016/j.ibmb.2017.06.008. [PMID: 28629966]
  • Rachel R Rix, G Christopher Cutler. Acute Exposure to Worst-Case Concentrations of Amitraz Does Not Affect Honey Bee Learning, Short-Term Memory, or Hemolymph Octopamine Levels. Journal of economic entomology. 2017 02; 110(1):127-132. doi: 10.1093/jee/tow250. [PMID: 28028168]
  • Hui-Min Li, Hong-Bo Jiang, Shun-Hua Gui, Xiao-Qiang Liu, Hong Liu, Xue-Ping Lu, Guy Smagghe, Jin-Jun Wang. Characterization of a β-Adrenergic-Like Octopamine Receptor in the Oriental Fruit Fly, Bactrocera dorsalis (Hendel). International journal of molecular sciences. 2016 Sep; 17(10):. doi: 10.3390/ijms17101577. [PMID: 27669213]
  • Poojan Pyakurel, Eve Privman Champaloux, B Jill Venton. Fast-Scan Cyclic Voltammetry (FSCV) Detection of Endogenous Octopamine in Drosophila melanogaster Ventral Nerve Cord. ACS chemical neuroscience. 2016 08; 7(8):1112-9. doi: 10.1021/acschemneuro.6b00070. [PMID: 27326831]
  • Jun Tao, Yi-Cheng Ma, Zhong-Shan Yang, Cheng-Gang Zou, Ke-Qin Zhang. Octopamine connects nutrient cues to lipid metabolism upon nutrient deprivation. Science advances. 2016 05; 2(5):e1501372. doi: 10.1126/sciadv.1501372. [PMID: 27386520]
  • Juliany Fontoura da Silva-Pereira, Gisele Adriana Bubna, Geferson de Almeida Gonçalves, Fabrício Bracht, Rosane Marina Peralta, Adelar Bracht. Fast hepatic biotransformation of p-synephrine and p-octopamine and implications for their oral intake. Food & function. 2016 Mar; 7(3):1483-91. doi: 10.1039/c6fo00014b. [PMID: 26883936]
  • Colin S Brent, Katelyn Miyasaki, Connor Vuong, Brittany Miranda, Bronwen Steele, Kristoffer G Brent, Rachna Nath. Regulatory roles of biogenic amines and juvenile hormone in the reproductive behavior of the western tarnished plant bug (Lygus hesperus). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2016 Feb; 186(2):169-79. doi: 10.1007/s00360-015-0953-1. [PMID: 26686231]
  • Monika Sobiech, Teresa Żołek, Piotr Luliński, Dorota Maciejewska. Separation of octopamine racemate on (R,S)-2-amino-1-phenylethanol imprinted polymer--Experimental and computational studies. Talanta. 2016; 146(?):556-67. doi: 10.1016/j.talanta.2015.05.074. [PMID: 26695304]
  • Yan Wu, Zheng-Rong Wu, Peng Chen, Yang-Li, Wan-Rong Deng, You-Quan Wang, Hong-Yu Li. Effect of the tyrosinase inhibitor (S)-N-trans-feruloyloctopamine from garlic skin on tyrosinase gene expression and melanine accumulation in melanoma cells. Bioorganic & medicinal chemistry letters. 2015 Apr; 25(7):1476-8. doi: 10.1016/j.bmcl.2015.02.028. [PMID: 25726329]
  • Shun-Fan Wu, Gang Xu, Gong-Yin Ye. Characterization of a tyramine receptor type 2 from hemocytes of rice stem borer, Chilo suppressalis. Journal of insect physiology. 2015 Apr; 75(?):39-46. doi: 10.1016/j.jinsphys.2015.03.004. [PMID: 25772095]
  • N Kirk Hillier, Rhys M B Kavanagh. Differential Octopaminergic Modulation of Olfactory Receptor Neuron Responses to Sex Pheromones in Heliothis virescens. PloS one. 2015; 10(12):e0143179. doi: 10.1371/journal.pone.0143179. [PMID: 26650832]
  • Piotr Luliński, Monika Sobiech, Teresa Zołek, Dorota Maciejewska. A separation of tyramine on a 2-(4-methoxyphenyl)ethylamine imprinted polymer: an answer from theoretical and experimental studies. Talanta. 2014 Nov; 129(?):155-64. doi: 10.1016/j.talanta.2014.05.029. [PMID: 25127579]
  • Shun-Fan Wu, Gang Xu, Yi-Xiang Qi, Ren-Ying Xia, Jia Huang, Gong-Yin Ye. Two splicing variants of a novel family of octopamine receptors with different signaling properties. Journal of neurochemistry. 2014 Apr; 129(1):37-47. doi: 10.1111/jnc.12526. [PMID: 24279508]
  • David M Raffel, Robert A Koeppe, Yong-Woon Jung, Guie Gu, Keun Sam Jang, Phillip S Sherman, Carole A Quesada. Quantification of cardiac sympathetic nerve density with N-11C-guanyl-meta-octopamine and tracer kinetic analysis. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2013 Sep; 54(9):1645-52. doi: 10.2967/jnumed.113.120659. [PMID: 23886728]
  • Giovanni D'Andrea, Domenico D'Amico, Gennaro Bussone, Andrea Bolner, Marco Aguggia, Maria G Saracco, Elisabetta Galloni, Valentina De Riva, Davide Colavito, Alberta Leon, Valeria Rosteghin, Francesco Perini. The role of tyrosine metabolism in the pathogenesis of chronic migraine. Cephalalgia : an international journal of headache. 2013 Aug; 33(11):932-7. doi: 10.1177/0333102413480755. [PMID: 23493762]
  • Jo-Anne C H Tan, Michael G K Jones, John Fosu-Nyarko. Gene silencing in root lesion nematodes (Pratylenchus spp.) significantly reduces reproduction in a plant host. Experimental parasitology. 2013 Feb; 133(2):166-78. doi: 10.1016/j.exppara.2012.11.011. [PMID: 23201220]
  • Markus Knaden, Bill S Hansson. Neuroscience. Specialized but flexible. Science (New York, N.Y.). 2013 Jan; 339(6116):151-2. doi: 10.1126/science.1232930. [PMID: 23307729]
  • Jeffrey A Riffell, Hong Lei, Leif Abrell, John G Hildebrand. Neural basis of a pollinator's buffet: olfactory specialization and learning in Manduca sexta. Science (New York, N.Y.). 2013 Jan; 339(6116):200-4. doi: 10.1126/science.1225483. [PMID: 23223454]
  • Shun-Fan Wu, Yao Yao, Jia Huang, Gong-Yin Ye. Characterization of a β-adrenergic-like octopamine receptor from the rice stem borer (Chilo suppressalis). The Journal of experimental biology. 2012 Aug; 215(Pt 15):2646-52. doi: 10.1242/jeb.068932. [PMID: 22786641]
  • Giovanni D'Andrea, Roberto Ostuzzi, Andrea Bolner, Davide Colavito, Alberta Leon. Is migraine a risk factor for the occurrence of eating disorders? Prevalence and biochemical evidences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2012 May; 33 Suppl 1(?):S71-6. doi: 10.1007/s10072-012-1045-6. [PMID: 22644175]
  • Mario Thevis, Anja Koch, Gerd Sigmund, Andreas Thomas, Wilhelm Schänzer. Analysis of octopamine in human doping control samples. Biomedical chromatography : BMC. 2012 May; 26(5):610-5. doi: 10.1002/bmc.1705. [PMID: 21932383]
  • Rita Gatti, Cinzia Lotti, Rita Morigi, Aldo Andreani. Determination of octopamine and tyramine traces in dietary supplements and phytoextracts by high performance liquid chromatography after derivatization with 2,5-dimethyl-1H-pyrrole-3,4-dicarbaldehyde. Journal of chromatography. A. 2012 Jan; 1220(?):92-100. doi: 10.1016/j.chroma.2011.11.060. [PMID: 22196247]
  • Taro Ueno, Jun Tomita, Shoen Kume, Kazuhiko Kume. Dopamine modulates metabolic rate and temperature sensitivity in Drosophila melanogaster. PloS one. 2012; 7(2):e31513. doi: 10.1371/journal.pone.0031513. [PMID: 22347491]
  • Jie-Ping Fan, Lu Zhang, Xue-Hong Zhang, Jun-zhong Huang, Sheng Tong, Tao Kong, Zhe-You Tian, Jian-Hang Zhu. Molecularly imprinted polymers for selective extraction of synephrine from Aurantii Fructus Immaturus. Analytical and bioanalytical chemistry. 2012 Jan; 402(3):1337-46. doi: 10.1007/s00216-011-5506-1. [PMID: 22086397]
  • Catherine Regnault-Roger, Charles Vincent, John Thor Arnason. Essential oils in insect control: low-risk products in a high-stakes world. Annual review of entomology. 2012; 57(?):405-24. doi: 10.1146/annurev-ento-120710-100554. [PMID: 21942843]
  • Nina Deisig, Jan Kropf, Simon Vitecek, Delphine Pevergne, Angela Rouyar, Jean-Christophe Sandoz, Philippe Lucas, Christophe Gadenne, Sylvia Anton, Romina Barrozo. Differential interactions of sex pheromone and plant odour in the olfactory pathway of a male moth. PloS one. 2012; 7(3):e33159. doi: 10.1371/journal.pone.0033159. [PMID: 22427979]
  • Josep Mercader, Estelle Wanecq, Jian Chen, Christian Carpéné. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. Journal of physiology and biochemistry. 2011 Sep; 67(3):443-52. doi: 10.1007/s13105-011-0078-2. [PMID: 21336650]
  • Hans-Joachim Pflüger, Carsten Duch. Dynamic neural control of insect muscle metabolism related to motor behavior. Physiology (Bethesda, Md.). 2011 Aug; 26(4):293-303. doi: 10.1152/physiol.00002.2011. [PMID: 21841077]
  • Rita Gatti, Cinzia Lotti. Development and validation of a pre-column reversed phase liquid chromatographic method with fluorescence detection for the determination of primary phenethylamines in dietary supplements and phytoextracts. Journal of chromatography. A. 2011 Jul; 1218(28):4468-73. doi: 10.1016/j.chroma.2011.05.044. [PMID: 21652038]
  • Berrin Ozçelik, Murat Kartal, Ilkay Orhan. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharmaceutical biology. 2011 Apr; 49(4):396-402. doi: 10.3109/13880209.2010.519390. [PMID: 21391841]
  • John G Seifert, Aaron Nelson, Julia Devonish, Edmund R Burke, Sidney J Stohs. Effect of acute administration of an herbal preparation on blood pressure and heart rate in humans. International journal of medical sciences. 2011 Mar; 8(3):192-7. doi: 10.7150/ijms.8.192. [PMID: 21448304]
  • Irina Sinakevitch, Julie A Mustard, Brian H Smith. Distribution of the octopamine receptor AmOA1 in the honey bee brain. PloS one. 2011 Jan; 6(1):e14536. doi: 10.1371/journal.pone.0014536. [PMID: 21267078]
  • Gunnar Kleinau, Juliane Pratzka, Daniela Nürnberg, Annette Grüters, Dagmar Führer-Sakel, Heiko Krude, Josef Köhrle, Torsten Schöneberg, Heike Biebermann. Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. PloS one. 2011; 6(10):e27073. doi: 10.1371/journal.pone.0027073. [PMID: 22073124]
  • Queenie W T Chan, Navdeep S Mutti, Leonard J Foster, Sarah D Kocher, Gro V Amdam, Florian Wolschin. The worker honeybee fat body proteome is extensively remodeled preceding a major life-history transition. PloS one. 2011; 6(9):e24794. doi: 10.1371/journal.pone.0024794. [PMID: 21969861]
  • Abul K Najmi, K K Pillai, S N Pal, M Akhtar, M Aqil, M Sharma. Effect of l-ornithine l-aspartate against thioacetamide-induced hepatic damage in rats. Indian journal of pharmacology. 2010 Dec; 42(6):384-7. doi: 10.4103/0253-7613.71926. [PMID: 21189911]
  • Ranil Waliwitiya, Peter Belton, Russell A Nicholson, Carl A Lowenberger. Effects of the essential oil constituent thymol and other neuroactive chemicals on flight motor activity and wing beat frequency in the blowfly Phaenicia sericata. Pest management science. 2010 Mar; 66(3):277-89. doi: 10.1002/ps.1871. [PMID: 19890946]
  • S A Adamo. Why should an immune response activate the stress response? Insights from the insects (the cricket Gryllus texensis). Brain, behavior, and immunity. 2010 Feb; 24(2):194-200. doi: 10.1016/j.bbi.2009.08.003. [PMID: 19679179]
  • Giovanni D'Andrea, Gianpietro Nordera, Gilberto Pizzolato, Andrea Bolner, Davide Colavito, Raffaella Flaibani, Alberta Leon. Trace amine metabolism in Parkinson's disease: low circulating levels of octopamine in early disease stages. Neuroscience letters. 2010 Jan; 469(3):348-51. doi: 10.1016/j.neulet.2009.12.025. [PMID: 20026245]
  • C Atgié, P Sauvant, L Ambid, C Carpéné. Possible mechanisms of weight loss of Siberian hamsters (Phodopus sungorus sungorus) exposed to short photoperiod. Journal of physiology and biochemistry. 2009 Dec; 65(4):377-86. doi: 10.1007/bf03185933. [PMID: 20358351]
  • Liaoyuan A Hu, Tian Zhou, Jinwoo Ahn, Shuli Wang, Julia Zhou, Yi Hu, Qingyun Liu. Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. The Biochemical journal. 2009 Oct; 424(1):39-45. doi: 10.1042/bj20090998. [PMID: 19725810]
  • C Rotte, C Krach, S Balfanz, A Baumann, B Walz, W Blenau. Molecular characterization and localization of the first tyramine receptor of the American cockroach (Periplaneta americana). Neuroscience. 2009 Sep; 162(4):1120-33. doi: 10.1016/j.neuroscience.2009.05.066. [PMID: 19482069]
  • Richard J Bloomer, Robert E Canale, Megan M Blankenship, Kelley G Hammond, Kelsey H Fisher-Wellman, Brian K Schilling. Effect of the dietary supplement Meltdown on catecholamine secretion, markers of lipolysis, and metabolic rate in men and women: a randomized, placebo controlled, cross-over study. Lipids in health and disease. 2009 Aug; 8(?):32. doi: 10.1186/1476-511x-8-32. [PMID: 19656409]
  • Xin Cheng Zhao, Bente Gunnveig Berg. Morphological and physiological characteristics of the serotonin-immunoreactive neuron in the antennal lobe of the male oriental tobacco budworm, Helicoverpa assulta. Chemical senses. 2009 Jun; 34(5):363-72. doi: 10.1093/chemse/bjp013. [PMID: 19304764]
  • Angela B Lange. Tyramine: from octopamine precursor to neuroactive chemical in insects. General and comparative endocrinology. 2009 May; 162(1):18-26. doi: 10.1016/j.ygcen.2008.05.021. [PMID: 18588893]
  • Giovanni D'Andrea, Roberto Ostuzzi, Federica Francesconi, Francesca Musco, Andrea Bolner, Florindo d'Onofrio, Davide Colavito. Migraine prevalence in eating disorders and pathophysiological correlations. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2009 May; 30 Suppl 1(?):S55-9. doi: 10.1007/s10072-009-0070-6. [PMID: 19415427]
  • Richard J Bloomer, Kelsey H Fisher-Wellman, Kelley G Hammond, Brian K Schilling, Adrianna A Weber, Bradford J Cole. Dietary supplement increases plasma norepinephrine, lipolysis, and metabolic rate in resistance trained men. Journal of the International Society of Sports Nutrition. 2009 01; 6(?):4. doi: 10.1186/1550-2783-6-4. [PMID: 19175919]
  • Radomír Socha, Dalibor Kodrík, Rostislav Zemek. Stimulatory effects of bioamines norepinephrine and dopamine on locomotion of Pyrrhocoris apterus (L.): is the adipokinetic hormone involved?. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2008 Nov; 151(3):305-10. doi: 10.1016/j.cbpb.2008.07.014. [PMID: 18707014]
  • Zhen-hua Wang, Hui Zhao, Jin-fu Li, Xian-dong Zeng, Jian-jun Chen, Han-li Feng, Jia-wen Xu. [Synergism of plant volatiles to insect pheromones and related mechanisms]. Ying yong sheng tai xue bao = The journal of applied ecology. 2008 Nov; 19(11):2533-7. doi: ". [PMID: 19238859]
  • Larry S Barak, Ali Salahpour, Xiaodong Zhang, Bernard Masri, Tatyana D Sotnikova, Amy J Ramsey, Jonathan D Violin, Robert J Lefkowitz, Marc G Caron, Raul R Gainetdinov. Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor. Molecular pharmacology. 2008 Sep; 74(3):585-594. doi: 10.1124/mol.108.048884. [PMID: 18524885]
  • Zhihua Xie, Gregory M Miller. Beta-phenylethylamine alters monoamine transporter function via trace amine-associated receptor 1: implication for modulatory roles of trace amines in brain. The Journal of pharmacology and experimental therapeutics. 2008 May; 325(2):617-28. doi: 10.1124/jpet.107.134247. [PMID: 18182557]
  • Giovanni D'Andrea, Roberto Ostuzzi, Andrea Bolner, Federica Francesconi, Francesca Musco, Florindo d'Onofrio, Davide Colavito. Study of tyrosine metabolism in eating disorders. Possible correlation with migraine. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2008 May; 29 Suppl 1(?):S88-92. doi: 10.1007/s10072-008-0895-4. [PMID: 18545905]
  • J G Stoffolano, M A Lim, K E Downer. Clonidine, octopaminergic receptor agonist, reduces protein feeding in the blow fly, Phormia regina (Meigen). Journal of insect physiology. 2007 Dec; 53(12):1293-9. doi: 10.1016/j.jinsphys.2007.07.002. [PMID: 17692332]
  • E P Masler. Responses of Heterodera glycines and Meloidogyne incognita to exogenously applied neuromodulators. Journal of helminthology. 2007 Dec; 81(4):421-7. doi: 10.1017/s0022149x07850243. [PMID: 18005465]
  • S Kang, K Kang, K Lee, K Back. Characterization of tryptamine 5-hydroxylase and serotonin synthesis in rice plants. Plant cell reports. 2007 Nov; 26(11):2009-15. doi: 10.1007/s00299-007-0405-9. [PMID: 17639402]
  • Qinglei Yu, Shulin Zhao, Fanggui Ye, Shuting Li. Determination of octopamine in human plasma by capillary electrophoresis with optical fiber light-emitting diode-induced fluorescence detection. Analytical biochemistry. 2007 Oct; 369(2):187-91. doi: 10.1016/j.ab.2007.06.014. [PMID: 17632069]
  • Karsten Putzbach, Catherine A Rimmer, Katherine E Sharpless, Stephen A Wise, Lane C Sander. Determination of bitter orange alkaloids in dietary supplement Standard Reference Materials by liquid chromatography with atmospheric-pressure ionization mass spectrometry. Analytical and bioanalytical chemistry. 2007 Sep; 389(1):197-205. doi: 10.1007/s00216-007-1409-6. [PMID: 17579842]
  • Federica Pellati, Stefania Benvenuti. Chromatographic and electrophoretic methods for the analysis of phenethylamine [corrected] alkaloids in Citrus aurantium. Journal of chromatography. A. 2007 Aug; 1161(1-2):71-88. doi: 10.1016/j.chroma.2007.05.097. [PMID: 17582424]
  • Sara Schaarschmidt, Joachim Kopka, Jutta Ludwig-Müller, Bettina Hause. Regulation of arbuscular mycorrhization by apoplastic invertases: enhanced invertase activity in the leaf apoplast affects the symbiotic interaction. The Plant journal : for cell and molecular biology. 2007 Aug; 51(3):390-405. doi: 10.1111/j.1365-313x.2007.03150.x. [PMID: 17521407]
  • Serenella A Sukno, Jamie McCuiston, Mui-Yun Wong, Xiaohong Wang, Michael R Thon, Richard Hussey, Thomas Baum, Eric Davis. Quantitative Detection of Double-Stranded RNA-Mediated Gene Silencing of Parasitism Genes in Heterodera glycines. Journal of nematology. 2007 Jun; 39(2):145-52. doi: ". [PMID: 19259483]
  • David M Raffel, Yong-Woon Jung, David L Gildersleeve, Phillip S Sherman, James J Moskwa, Louis J Tluczek, Wei Chen. Radiolabeled phenethylguanidines: novel imaging agents for cardiac sympathetic neurons and adrenergic tumors. Journal of medicinal chemistry. 2007 May; 50(9):2078-88. doi: 10.1021/jm061398y. [PMID: 17419605]
  • Zhihua Xie, Susan V Westmoreland, Mary E Bahn, Guo-Lin Chen, Hong Yang, Eric J Vallender, Wei-Dong Yao, Bertha K Madras, Gregory M Miller. Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. The Journal of pharmacology and experimental therapeutics. 2007 Apr; 321(1):116-27. doi: 10.1124/jpet.106.116863. [PMID: 17234900]
  • Mark C Roman, Joseph M Betz, Jana Hildreth. Determination of synephrine in bitter orange raw materials, extracts, and dietary supplements by liquid chromatography with ultraviolet detection: single-laboratory validation. Journal of AOAC International. 2007 Jan; 90(1):68-81. doi: . [PMID: 17373438]
  • Stanley Caveney, Wendy Cladman, LouAnn Verellen, Cam Donly. Ancestry of neuronal monoamine transporters in the Metazoa. The Journal of experimental biology. 2006 Dec; 209(Pt 24):4858-68. doi: 10.1242/jeb.02607. [PMID: 17142674]
  • Christian Carpéné, Danièle Daviaud, Jeremie Boucher, Sandy Bour, Virgile Visentin, Sandra Grès, Carine Duffaut, Emi Fontana, Xavier Testar, Jean-Sébastien Saulnier-Blache, Philippe Valet. Short- and long-term insulin-like effects of monoamine oxidases and semicarbazide-sensitive amine oxidase substrates in cultured adipocytes. Metabolism: clinical and experimental. 2006 Oct; 55(10):1397-405. doi: 10.1016/j.metabol.2006.06.011. [PMID: 16979412]
  • Lutz Auerswald, Gerd Gäde. Endocrine control of TAG lipase in the fat body of the migratory locust, Locusta migratoria. Insect biochemistry and molecular biology. 2006 Oct; 36(10):759-68. doi: 10.1016/j.ibmb.2006.07.004. [PMID: 17027842]
  • K Mittelstrass, D Treutter, M Plessl, W Heller, E F Elstner, I Heiser. Modification of primary and secondary metabolism of potato plants by nitrogen application differentially affects resistance to Phytophthora infestans and Alternaria solani. Plant biology (Stuttgart, Germany). 2006 Sep; 8(5):653-61. doi: 10.1055/s-2006-924085. [PMID: 16821190]
  • Fei Tang, Liang Tao, Xubiao Luo, Li Ding, Manli Guo, Lihua Nie, Shouzhuo Yao. Determination of octopamine, synephrine and tyramine in Citrus herbs by ionic liquid improved 'green' chromatography. Journal of chromatography. A. 2006 Sep; 1125(2):182-8. doi: 10.1016/j.chroma.2006.05.049. [PMID: 16781718]
  • G D'Andrea, F Granella, M Leone, F Perini, A Farruggio, G Bussone. Abnormal platelet trace amine profiles in migraine with and without aura. Cephalalgia : an international journal of headache. 2006 Aug; 26(8):968-72. doi: 10.1111/j.1468-2982.2006.01141.x. [PMID: 16886933]
  • David N Price, Michael S Berry. Comparison of effects of octopamine and insecticidal essential oils on activity in the nerve cord, foregut, and dorsal unpaired median neurons of cockroaches. Journal of insect physiology. 2006 Mar; 52(3):309-19. doi: 10.1016/j.jinsphys.2005.11.010. [PMID: 16406398]
  • Christine A Haller, Neal L Benowitz, Peyton Jacob. Hemodynamic effects of ephedra-free weight-loss supplements in humans. The American journal of medicine. 2005 Sep; 118(9):998-1003. doi: 10.1016/j.amjmed.2005.02.034. [PMID: 16164886]
  • Raghu Prasad Rao Metpally, Ramanathan Sowdhamini. Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors. BMC genomics. 2005 Aug; 6(?):106. doi: 10.1186/1471-2164-6-106. [PMID: 16091152]
  • Irina Sinakevitch, Mamiko Niwa, Nicholas J Strausfeld. Octopamine-like immunoreactivity in the honey bee and cockroach: comparable organization in the brain and subesophageal ganglion. The Journal of comparative neurology. 2005 Aug; 488(3):233-54. doi: 10.1002/cne.20572. [PMID: 15952163]
  • Essam E Enan. Molecular and pharmacological analysis of an octopamine receptor from American cockroach and fruit fly in response to plant essential oils. Archives of insect biochemistry and physiology. 2005 Jul; 59(3):161-71. doi: 10.1002/arch.20076. [PMID: 15986384]
  • Lutz Auerswald, Karl J Siegert, Gerd Gäde. Activation of triacylglycerol lipase in the fat body of a beetle by adipokinetic hormone. Insect biochemistry and molecular biology. 2005 May; 35(5):461-70. doi: 10.1016/j.ibmb.2005.01.010. [PMID: 15804579]
  • Fumio Matsuda, Keiko Morino, Rieko Ano, Masaki Kuzawa, Kyo Wakasa, Hisashi Miyagawa. Metabolic flux analysis of the phenylpropanoid pathway in elicitor-treated potato tuber tissue. Plant & cell physiology. 2005 Mar; 46(3):454-66. doi: 10.1093/pcp/pci042. [PMID: 15695456]