2,2',4,4'-Tetrachlorobiphenyl (BioDeep_00000009784)
Secondary id: BioDeep_00001875228
human metabolite blood metabolite Industrial Pollutants Exogenous
代谢物信息卡片
化学式: C12H6Cl4 (289.9224)
中文名称: 2,2,4,4-四氯联苯
谱图信息:
最多检出来源 () 0%
Last reviewed on 2024-08-07.
Cite this Page
2,2',4,4'-Tetrachlorobiphenyl. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/2,2_,4,4_-tetrachlorobiphenyl (retrieved
2024-12-23) (BioDeep RN: BioDeep_00000009784). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C1=CC(=C(C=C1Cl)Cl)C2=C(C=C(C=C2)Cl)Cl
InChI: InChI=1S/C12H6Cl4/c13-7-1-3-9(11(15)5-7)10-4-2-8(14)6-12(10)16/h1-6H
描述信息
2,2',4,4'-tetrachlorobiphenyl is a tetrachlorobiphenyl that is biphenyl in which each of the phenyl groups is substituted at positions 2 and 4 by chlorines. It is a tetrachlorobiphenyl and a dichlorobenzene.
D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:34204
- KEGG: C14247
- PubChem: 17097
- HMDB: HMDB0245370
- Metlin: METLIN69908
- ChEMBL: CHEMBL137283
- chemspider: 16182
- CAS: 2437-79-8
- PMhub: MS000023602
- NIKKAJI: J134.536B
- PubChem: 7847057
- KNApSAcK: 34204
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Margaret R Bell, Ariel Dryden, Ryan Will, Andrea C Gore. Sex differences in effects of gestational polychlorinated biphenyl exposure on hypothalamic neuroimmune and neuromodulator systems in neonatal rats.
Toxicology and applied pharmacology.
2018 08; 353(?):55-66. doi:
10.1016/j.taap.2018.06.002. [PMID: 29879404] - M B Wigestrand, M Stenberg, S I Walaas, F Fonnum, P L Andersson. Non-dioxin-like PCBs inhibit [(3)H]WIN-35,428 binding to the dopamine transporter: a structure-activity relationship study.
Neurotoxicology.
2013 Dec; 39(?):18-24. doi:
10.1016/j.neuro.2013.07.005. [PMID: 23933243] - Robert F Herrick, John D Meeker, Larisa Altshul. Serum PCB levels and congener profiles among teachers in PCB-containing schools: a pilot study.
Environmental health : a global access science source.
2011 Jun; 10(?):56. doi:
10.1186/1476-069x-10-56. [PMID: 21668970] - Michel Aubé, Christian Larochelle, Pierre Ayotte. Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
Environmental research.
2011 Apr; 111(3):337-47. doi:
10.1016/j.envres.2011.01.010. [PMID: 21295777] - L Umannová, J Neca, Z Andrysík, J Vondrácek, B L Upham, J E Trosko, J Hofmanová, A Kozubík, M Machala. Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling.
Toxicology.
2008 May; 247(1):55-60. doi:
10.1016/j.tox.2008.02.002. [PMID: 18367304] - Gregory D Lyng, Abigail Snyder-Keller, Richard F Seegal. Polychlorinated biphenyl-induced neurotoxicity in organotypic cocultures of developing rat ventral mesencephalon and striatum.
Toxicological sciences : an official journal of the Society of Toxicology.
2007 May; 97(1):128-39. doi:
10.1093/toxsci/kfm027. [PMID: 17324953] - C Edwin Garner, Jennifer Demeter, H B Matthews. The effect of chlorine substitution on the disposition of polychlorinated biphenyls following dermal administration.
Toxicology and applied pharmacology.
2006 Oct; 216(1):157-67. doi:
10.1016/j.taap.2006.04.013. [PMID: 16784763] - Douglas A Donahue, Edward J Dougherty, Lee A Meserve. Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats.
Toxicology.
2004 Oct; 203(1-3):99-107. doi:
10.1016/j.tox.2004.06.011. [PMID: 15363586] - Hong Fang, Weida Tong, William S Branham, Carrie L Moland, Stacy L Dial, Huixiao Hong, Qian Xie, Roger Perkins, William Owens, Daniel M Sheehan. Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Chemical research in toxicology.
2003 Oct; 16(10):1338-58. doi:
10.1021/tx030011g. [PMID: 14565775] - A Saeed, L G Hansen. Morphometric changes in the prepubertal female rat thyroid gland following acute exposure to 2,2',4,4'-tetrachlorobiphenyl and Aroclor 1242.
Journal of toxicology and environmental health.
1997 Aug; 51(5):503-13. doi:
10.1080/00984109708984040. [PMID: 9233383] - K Haraguchi, Y Masuda, Y Kato, R Kimura. [Tissue retention of hydroxy and methylsulfonyl metabolites of 2, 2', 4, 4'-tetrachlorobiphenyl in rats].
Fukuoka igaku zasshi = Hukuoka acta medica.
1995 May; 86(5):163-8. doi:
NULL. [PMID: 7628803] - M J Vodicnik. The effect of pregnancy and lactation on the disposition of [2,4,2',4'-14C]tetrachlorobiphenyl in the mouse.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1986 Jan; 6(1):53-61. doi:
10.1016/0272-0590(86)90263-0. [PMID: 3086170] - J B Hook, C R Elcombe, M S Rose, E A Lock. Characterization of the effects of known hepatic monooxygenase inducers on male and female rat and mouse kidneys.
Life sciences.
1982 Sep; 31(11):1077-84. doi:
10.1016/0024-3205(82)90080-7. [PMID: 6815396]
