10-Hydroxydecanoic acid (BioDeep_00000001276)
Secondary id: BioDeep_00000406073
human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019 natural product
代谢物信息卡片
化学式: C10H20O3 (188.1412)
中文名称: 10-羟基癸酸, 10羟基癸酸
谱图信息:
最多检出来源 Homo sapiens(blood) 17.12%
Last reviewed on 2024-07-04.
Cite this Page
10-Hydroxydecanoic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/10-hydroxydecanoic_acid (retrieved
2024-12-23) (BioDeep RN: BioDeep_00000001276). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C(CCCCC(=O)O)CCCCO
InChI: InChI=1S/C10H20O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h11H,1-9H2,(H,12,13)
描述信息
10-hydroxycapric acid is a 10-carbon, omega-hydroxy fatty acid, shown to be the preferred hydroxylation product (together with the 9-OH isomer) of capric acid in biosystems, and used as a standard in lipid assays; reported to have cytotoxic effects. It is a straight-chain saturated fatty acid and an omega-hydroxy-medium-chain fatty acid. It is functionally related to a decanoic acid. It is a conjugate acid of a 10-hydroxycaprate.
10-Hydroxydecanoic acid, also known as 10-OH-capric acid or 10-OH-caprate, belongs to the class of organic compounds known as medium-chain hydroxy acids and derivatives. These are hydroxy acids with a 6 to 12 carbon atoms long side chain. Based on a literature review a significant number of articles have been published on 10-Hydroxydecanoic acid. This compound has been identified in human blood as reported by (PMID: 31557052 ). 10-hydroxydecanoic acid is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically 10-Hydroxydecanoic acid is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
10-Hydroxydecanoic acid (NSC 15139) is a saturated fatty acid of 10-hydroxy-trans-2-decenoic acid from royal jelly, with anti-inflammatory activity[1].
同义名列表
16 个代谢物同义名
10-hydroxy-decanoic acid; 10-Hydroxydecanoic acid; 10-hydroxy capric acid; 10-OH-Decanoic acid; 10-Hydroxydecanoate; 10-Hydroxy caprate; 10-Hydroxycaprate; 10-OH-Capric acid; 10-OH-Decanoate; 10-OH-Caprate; 10-HDAA CPD; 10HDA CPD; 10-Hydroxydecanoate; NSC 15139; 10-Hydroxydecanoic acid; 10-Hydroxydecanoic acid
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:17409
- KEGG: C02774
- PubChem: 74300
- HMDB: HMDB0244272
- Metlin: METLIN35414
- ChEMBL: CHEMBL4519263
- MetaCyc: 10-HYDROXYDECANOATE
- CAS: 1679-53-4
- MoNA: KO001112
- MoNA: KO001111
- MoNA: KO001113
- MoNA: KO001114
- PMhub: MS000000250
- PubChem: 5726
- LipidMAPS: LMFA01050033
- 3DMET: B01599
- NIKKAJI: J195.322B
- RefMet: 10-Hydroxydecanoic acid
- medchemexpress: HY-Y0148
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-433
- KNApSAcK: 17409
- LOTUS: LTS0190389
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
9 个相关的物种来源信息
- 40674 - Animals: -
- 33682 - Euglenozoa: LTS0190389
- 2759 - Eukaryota: LTS0190389
- 9606 - Homo sapiens: -
- 5653 - Kinetoplastea: LTS0190389
- 5690 - Trypanosoma: LTS0190389
- 5691 - Trypanosoma brucei: 10.1128/AAC.00044-13
- 5691 - Trypanosoma brucei: LTS0190389
- 5654 - Trypanosomatidae: LTS0190389
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Carine Jacques, Emilien L Jamin, Isabelle Jouanin, Cécile Canlet, Marie Tremblay-Franco, Jean-François Martin, Daniel Zalko, Yves Brunel, Sandrine Bessou-Touya, Laurent Debrauwer, Pierre-Jacques Ferret, Hélène Duplan. Safety assessment of cosmetics by read across applied to metabolomics data of in vitro skin and liver models.
Archives of toxicology.
2021 10; 95(10):3303-3322. doi:
10.1007/s00204-021-03136-7. [PMID: 34459931] - Takafumi Toyohara, Takehiro Suzuki, Yasutoshi Akiyama, Daisuke Yoshihara, Yoichi Takeuchi, Eikan Mishima, Koichi Kikuchi, Chitose Suzuki, Masayuki Tanemoto, Sadayoshi Ito, Shizuko Nagao, Tomoyoshi Soga, Takaaki Abe. Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model.
Clinical and experimental nephrology.
2011 Oct; 15(5):676-687. doi:
10.1007/s10157-011-0467-4. [PMID: 21695416] - Yuko Terada, Masataka Narukawa, Tatsuo Watanabe. Specific hydroxy fatty acids in royal jelly activate TRPA1.
Journal of agricultural and food chemistry.
2011 Mar; 59(6):2627-35. doi:
10.1021/jf1041646. [PMID: 21348496] - Juyoung Kim, Youngae Kim, Hyejeong Yun, Hyemin Park, Sun Yeou Kim, Kwang-Gill Lee, Sang-Mi Han, Yunhi Cho. Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model.
Nutrition research and practice.
2010 Oct; 4(5):362-8. doi:
10.4162/nrp.2010.4.5.362. [PMID: 21103081] - Asmaa El Hamidi, Alexey Novikov, Doris Karibian, Malcolm B Perry, Martine Caroff. Structural characterization of Bordetella parapertussis lipid A.
Journal of lipid research.
2009 May; 50(5):854-9. doi:
10.1194/jlr.m800454-jlr200. [PMID: 19017615]
