Icosatrienoic acid (BioDeep_00001872029)

Main id: BioDeep_00000002831

 


代谢物信息卡片


(11Z,14Z,17Z)-Eicosa-11,14,17-trienoic acid

化学式: C20H34O2 (306.2559)
中文名称: 顺式-11,14,17-二十碳三烯酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC=CCC=CCC=CCCCCCCCCCC(=O)O
InChI: InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10H,2,5,8,11-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ACADL, ALB, ALOX5, CDH1, GLA, PLA2G12A, PTGS2, TBX20
Peripheral membrane protein 4 ACHE, ALOX5, AP1S2, PTGS2
Endoplasmic reticulum membrane 5 FADS1, FADS2, GLA, PTGS2, SCD
Nucleus 5 ACHE, ALB, CDH1, PLCZ1, TBX20
cytosol 6 ALB, ALOX5, AP1S2, CDH1, PLCZ1, PRKCQ
mitochondrial membrane 1 ACADL
trans-Golgi network 1 CDH1
centrosome 1 ALB
nucleoplasm 3 ALOX5, CDH1, PLCZ1
Cell membrane 4 ACHE, CDH1, TBXA2R, TNF
Cytoplasmic side 1 AP1S2
lamellipodium 1 CDH1
Multi-pass membrane protein 4 FADS1, FADS2, SCD, TBXA2R
Synapse 1 ACHE
cell junction 1 CDH1
cell surface 2 ACHE, TNF
glutamatergic synapse 1 CDH1
Golgi apparatus 5 ACHE, ALB, AP1S2, CDH1, GLA
Golgi membrane 2 AP1S2, INS
lysosomal membrane 1 AP1S2
neuromuscular junction 1 ACHE
neuronal cell body 1 TNF
postsynapse 1 CDH1
Cytoplasm, cytosol 1 ALOX5
Lysosome 1 GLA
acrosomal vesicle 1 TBXA2R
endosome 1 CDH1
plasma membrane 7 ACHE, CDH1, F2, FADS2, PRKCQ, TBXA2R, TNF
Membrane 6 ACHE, CDH1, FADS1, FADS2, GLA, SCD
caveola 1 PTGS2
extracellular exosome 4 ALB, CDH1, F2, GLA
endoplasmic reticulum 3 ALB, PTGS2, SCD
extracellular space 7 ACHE, ALB, ALOX5, F2, IL6, INS, TNF
lysosomal lumen 1 GLA
perinuclear region of cytoplasm 4 ACHE, ALOX5, CDH1, PLCZ1
adherens junction 1 CDH1
mitochondrion 2 ACADL, FADS1
protein-containing complex 2 ALB, PTGS2
intracellular membrane-bounded organelle 2 AP1S2, FADS1
Microsome membrane 1 PTGS2
pronucleus 1 PLCZ1
Single-pass type I membrane protein 1 CDH1
Secreted 6 ACHE, ALB, F2, IL6, INS, PLA2G12A
extracellular region 10 ACHE, ALB, ALOX5, CDH1, F2, GLA, IL6, INS, PLA2G12A, TNF
cytoplasmic side of plasma membrane 1 CDH1
Mitochondrion matrix 1 ACADL
mitochondrial matrix 1 ACADL
Extracellular side 1 ACHE
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
Nucleus membrane 1 ALOX5
nuclear membrane 2 ALOX5, CDH1
external side of plasma membrane 1 TNF
actin cytoskeleton 1 CDH1
nucleolus 2 PLCZ1, SCD
Early endosome 1 AP1S2
Membrane, clathrin-coated pit 1 AP1S2
clathrin-coated pit 1 AP1S2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 2 ALOX5, PLCZ1
Membrane raft 1 TNF
Cell junction, adherens junction 1 CDH1
flotillin complex 1 CDH1
basement membrane 1 ACHE
collagen-containing extracellular matrix 1 F2
lateral plasma membrane 1 CDH1
nuclear speck 1 TBXA2R
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
ciliary basal body 1 ALB
chromatin 1 TBX20
phagocytic cup 1 TNF
centriole 1 ALB
Golgi apparatus, trans-Golgi network 1 CDH1
spindle pole 1 ALB
blood microparticle 2 ALB, F2
Lipid-anchor, GPI-anchor 1 ACHE
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
Endomembrane system 1 AP1S2
endosome lumen 1 INS
[Isoform 1]: Endoplasmic reticulum membrane 1 FADS1
Cytoplasmic vesicle membrane 1 AP1S2
side of membrane 1 ACHE
trans-Golgi network membrane 1 AP1S2
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 2 ALOX5, INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 5 ALB, F2, IL6, INS, PTGS2
nuclear matrix 1 ALOX5
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
azurophil granule lumen 1 GLA
anaphase-promoting complex 1 CDH1
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GLA, INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
endoplasmic reticulum-Golgi intermediate compartment 1 GLA
[Isoform 2]: Nucleus 1 CDH1
synaptic cleft 1 ACHE
apical junction complex 1 CDH1
AP-type membrane coat adaptor complex 1 AP1S2
membrane coat 1 AP1S2
AP-1 adaptor complex 1 AP1S2
[Isoform 2]: Endoplasmic reticulum membrane 1 FADS1
Cell junction, desmosome 1 CDH1
desmosome 1 CDH1
catenin complex 1 CDH1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
sperm head 1 PLCZ1
interleukin-6 receptor complex 1 IL6
Nucleus intermembrane space 1 ALOX5
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • Woo Jung Park, Kumar S D Kothapalli, Peter Lawrence, Cynthia Tyburczy, J Thomas Brenna. An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta8-desaturates 20:2n-6 and 20:3n-3. Journal of lipid research. 2009 Jun; 50(6):1195-202. doi: 10.1194/jlr.m800630-jlr200. [PMID: 19202133]
  • Eric D Bruder, Ping C Lee, Hershel Raff. Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. Endocrinology. 2004 Nov; 145(11):5364-72. doi: 10.1210/en.2004-0582. [PMID: 15271879]
  • D Wang, T J Girard, T P Kasten, R M LaChance, M A Miller-Wideman, R C Durley. Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex. Journal of natural products. 1998 Nov; 61(11):1352-5. doi: 10.1021/np980117p. [PMID: 9834151]