3-Hydroxy-3-Carboxy-Adipic Acid (BioDeep_00001869336)

Main id: BioDeep_00000004630

 


代谢物信息卡片


3-Hydroxy-3-Carboxy-Adipic Acid

化学式: C7H10O7 (206.0427)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CC(CC(=O)O)(C(=O)O)O)C(=O)O
InChI: InChI=1S/C7H10O7/c8-4(9)1-2-7(14,6(12)13)3-5(10)11/h14H,1-3H2,(H,8,9)(H,10,11)(H,12,13)/t7-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

3-Hydroxy-3-Carboxy-Adipic Acid



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 EGFR, IGHMBP2, NAA10, RPS3A, S100A9, SOD1, ZMYND8
Peripheral membrane protein 3 CYP1B1, HSD17B6, S100A9
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 2 CYP1B1, EGFR
Nucleus 10 CS, EGFR, FEN1, IGHMBP2, NAA10, PSMD4, RPS3A, S100A9, SOD1, ZMYND8
cytosol 6 HMGCL, NAA10, PSMD4, RPS3A, S100A9, SOD1
nuclear body 1 IGHMBP2
nucleoplasm 7 ATP2B1, FEN1, IGHMBP2, PSMD4, RPS3A, SOD1, ZMYND8
Cell membrane 4 ATP2B1, EGFR, S100A9, SLC38A5
ruffle membrane 1 EGFR
Cell projection, axon 1 IGHMBP2
Early endosome membrane 2 EGFR, HSD17B6
Multi-pass membrane protein 2 ATP2B1, SLC38A5
Synapse 2 ATP2B1, RPS3A
cell junction 1 EGFR
cell surface 1 EGFR
dendritic shaft 1 ZMYND8
glutamatergic synapse 2 ATP2B1, EGFR
Golgi apparatus 1 FUT2
Golgi membrane 2 EGFR, FUT2
growth cone 1 IGHMBP2
neuronal cell body 1 SOD1
presynaptic membrane 1 ATP2B1
endosome 1 EGFR
plasma membrane 4 ATP2B1, EGFR, S100A9, SLC38A5
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ATP2B1, CS, CYP1B1, EGFR, FEN1, IGHMBP2, NAA10, SLC38A5
apical plasma membrane 1 EGFR
axon 1 IGHMBP2
basolateral plasma membrane 2 ATP2B1, EGFR
extracellular exosome 6 ATP2B1, CS, FUT2, RPS3A, S100A9, SOD1
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 HSD17B6, RPS3A
extracellular space 3 EGFR, S100A9, SOD1
perinuclear region of cytoplasm 1 EGFR
mitochondrion 5 CS, CYP1B1, FEN1, HMGCL, SOD1
protein-containing complex 4 EGFR, FEN1, HMGCL, SOD1
intracellular membrane-bounded organelle 3 ATP2B1, CYP1B1, HSD17B6
Microsome membrane 2 CYP1B1, HSD17B6
Single-pass type I membrane protein 1 EGFR
extracellular region 2 S100A9, SOD1
Mitochondrion matrix 2 CS, HMGCL
mitochondrial matrix 3 CS, HMGCL, SOD1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 EGFR
dendritic spine 1 ZMYND8
cytoplasmic vesicle 1 SOD1
nucleolus 4 FEN1, NAA10, RPS3A, ZMYND8
axon cytoplasm 1 SOD1
Single-pass type II membrane protein 1 FUT2
Membrane raft 1 EGFR
Cytoplasm, cytoskeleton 1 S100A9
focal adhesion 2 EGFR, RPS3A
Peroxisome 2 HMGCL, SOD1
intracellular vesicle 1 EGFR
peroxisomal matrix 1 HMGCL
mitochondrial intermembrane space 1 SOD1
collagen-containing extracellular matrix 1 S100A9
lateral plasma membrane 1 ATP2B1
dendrite cytoplasm 1 SOD1
receptor complex 1 EGFR
chromatin 1 ZMYND8
cell projection 1 ATP2B1
Chromosome 1 ZMYND8
cytoskeleton 1 S100A9
Nucleus, nucleolus 2 FEN1, RPS3A
chromosome, telomeric region 1 FEN1
Basolateral cell membrane 1 ATP2B1
Nucleus, nucleoplasm 1 FEN1
Golgi cisterna membrane 1 FUT2
Presynaptic cell membrane 1 ATP2B1
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
proteasome accessory complex 1 PSMD4
proteasome complex 1 PSMD4
secretory granule lumen 1 S100A9
Golgi apparatus, Golgi stack membrane 1 FUT2
small-subunit processome 1 RPS3A
immunological synapse 1 ATP2B1
clathrin-coated endocytic vesicle membrane 1 EGFR
ribonucleoprotein complex 2 IGHMBP2, RPS3A
cytosolic ribosome 1 RPS3A
site of DNA damage 1 ZMYND8
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
ribosome 1 RPS3A
calprotectin complex 1 S100A9
S100A9 complex 1 S100A9
cytosolic small ribosomal subunit 1 RPS3A
photoreceptor ribbon synapse 1 ATP2B1
proteasome regulatory particle, base subcomplex 1 PSMD4
[Isoform FENMIT]: Mitochondrion 1 FEN1
NatA complex 1 NAA10


文献列表

  • Tsuneo Hakoyama, Kaori Niimi, Hirokazu Watanabe, Ryohei Tabata, Junichi Matsubara, Shusei Sato, Yasukazu Nakamura, Satoshi Tabata, Li Jichun, Tsuyoshi Matsumoto, Kazuyuki Tatsumi, Mika Nomura, Shigeyuki Tajima, Masumi Ishizaka, Koji Yano, Haruko Imaizumi-Anraku, Masayoshi Kawaguchi, Hiroshi Kouchi, Norio Suganuma. Host plant genome overcomes the lack of a bacterial gene for symbiotic nitrogen fixation. Nature. 2009 Nov; 462(7272):514-7. doi: 10.1038/nature08594. [PMID: 19940927]
  • Dehua Zhao, Leonardo Curatti, Luis M Rubio. Evidence for nifU and nifS participation in the biosynthesis of the iron-molybdenum cofactor of nitrogenase. The Journal of biological chemistry. 2007 Dec; 282(51):37016-25. doi: 10.1074/jbc.m708097200. [PMID: 17959596]
  • Leonardo Curatti, Jose A Hernandez, Robert Y Igarashi, Basem Soboh, Dehua Zhao, Luis M Rubio. In vitro synthesis of the iron-molybdenum cofactor of nitrogenase from iron, sulfur, molybdenum, and homocitrate using purified proteins. Proceedings of the National Academy of Sciences of the United States of America. 2007 Nov; 104(45):17626-31. doi: 10.1073/pnas.0703050104. [PMID: 17978192]
  • Jinghua Qian, Ann H West, Paul F Cook. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct; 45(39):12136-43. doi: 10.1021/bi060889h. [PMID: 17002313]
  • J P van Rooyen, L J Mienie, E Erasmus, W J de Wet, M Duran, S K Wadman. Urinary excretion of homocitric acid and methylhomocitric acid in propionic acidaemia: minor metabolic products of the citrate synthase aldol condensation reaction. Clinica chimica acta; international journal of clinical chemistry. 1994 Oct; 230(1):91-9. doi: 10.1016/0009-8981(94)90092-2. [PMID: 7850997]