Penicillamine (BioDeep_00001867837)
Main id: BioDeep_00000004142
Chemicals and Drugs
代谢物信息卡片
D-penicillamine
化学式: C5H11NO2S (149.051)
中文名称: D-青霉胺, 青霉胺
谱图信息:
最多检出来源 () 0%
Reviewed
Last reviewed on 2024-08-12.
Cite this Page
Penicillamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/penicillamine (retrieved
2024-12-22) (BioDeep RN: BioDeep_00001867837). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(C)(C(C(=O)O)N)S
InChI: InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)
描述信息
An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01C - Specific antirheumatic agents > M01CC - Penicillamine and similar agents
C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C1971 - Angiogenesis Activator Inhibitor
D064449 - Sequestering Agents > D002614 - Chelating Agents
D020011 - Protective Agents > D000931 - Antidotes
D018501 - Antirheumatic Agents
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine increases free copper and enhances oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria[1][2][3][4].
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:50868
- ChEBI: CHEBI:7959
- KEGG: C07418
- KEGGdrug: D00496
- PubChem: 5852
- DrugBank: DB00859
- ChEMBL: CHEMBL1430
- MeSH: Penicillamine
- CAS: 52-67-5
- MetaboLights: MTBLC50868
- PDB-CCD: LEI
- NIKKAJI: J9.116B
- RefMet: Penicillamine
- medchemexpress: HY-B0300
- PubChem: 9622
- KNApSAcK: 7959
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Liangjie Zhang, Ling Zhu, Chunling Ci, Wenlong Ai, Yu Wang, Xun Wang. A case of Wilson's disease combined with intracranial lipoma and dysplasia of the corpus callosum with review of the literature.
BMC neurology.
2024 Jan; 24(1):44. doi:
10.1186/s12883-024-03541-2. [PMID: 38273263] - Yue Pu, Juan Zhang, Nian Peng, Rui Li, Dao-Jun Xie, Rong-Xin Zhang, Lan-Ting Sun, Jin-le Wang, Hao Ye. 1H NMR-based metabolomic study of striatal injury in rats with copper-loaded Wilson's disease by Chinese and Western medicine intervention.
Journal of pharmaceutical and biomedical analysis.
2023 Mar; 229(?):115355. doi:
10.1016/j.jpba.2023.115355. [PMID: 37018958] - Kuiyu Chen, Limin Wu, Qianzhuo Liu, Fang Tan, Luyao Wang, Dan Zhao, Xinru Fang, Xiang Liu, Jiabo Liu, Hui Han. Glutathione improves testicular spermatogenesis through inhibiting oxidative stress, mitochondrial damage, and apoptosis induced by copper deposition in mice with Wilson disease.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Feb; 158(?):114107. doi:
10.1016/j.biopha.2022.114107. [PMID: 36502753] - Milad Baghal Behyar, Fatemeh Farshchi, Mohammad Hasanzadeh. Sensitive recognition of prostate-specific antigen using biotinylated antibody encapsulated on D-penicillamine decorated wrinkled silicate nanoparticles (WSN): An innovative sandwich-type biosensor toward diagnosis of prostate cancer.
Journal of molecular recognition : JMR.
2022 08; 35(8):e2960. doi:
10.1002/jmr.2960. [PMID: 35426958] - Brock Brady, Wuwei Li, Nashwan Farooque, Christopher Ehrhardt, Mark E Meyerhoff, Xuewei Wang. S-Nitrosothiol-Impregnated Silicone Catheter for Colorimetric Sensing of Indole and E. coli: Toward On-Body Detection of Urinary Tract Infections.
ACS sensors.
2022 06; 7(6):1712-1719. doi:
10.1021/acssensors.2c00439. [PMID: 35604028] - Katalin Despotov, Péter Klivényi, István Nagy, Attila Pálvölgyi, László Vécsei, Cecília Rajda. Rare co-occurrence of multiple sclerosis and Wilson's disease - case report.
BMC neurology.
2022 May; 22(1):178. doi:
10.1186/s12883-022-02691-5. [PMID: 35578211] - Sabine Borchard, Stefanie Raschke, Krzysztof M Zak, Carola Eberhagen, Claudia Einer, Elisabeth Weber, Sandra M Müller, Bernhard Michalke, Josef Lichtmannegger, Albrecht Wieser, Tamara Rieder, Grzegorz M Popowicz, Jerzy Adamski, Martin Klingenspor, Andrew H Coles, Ruth Viana, Mikkel H Vendelbo, Thomas D Sandahl, Tanja Schwerdtle, Thomas Plitz, Hans Zischka. Bis-choline tetrathiomolybdate prevents copper-induced blood-brain barrier damage.
Life science alliance.
2022 03; 5(3):. doi:
10.26508/lsa.202101164. [PMID: 34857647] - Sanjay Kumar, Biswa Ranjan Patra, Mohammed Irtaza, Praveen Kumar Rao, Suprabhat Giri, Harish Darak, Amrit Gopan, Aditya Kale, Akash Shukla. Adverse Events with D-penicillamine Therapy in Hepatic Wilson's Disease: A Single-Center Retrospective Audit.
Clinical drug investigation.
2022 Feb; 42(2):177-184. doi:
10.1007/s40261-022-01117-x. [PMID: 35102516] - Wei Zhang, Yu Zhang, Xin Liu, Yue Zhang, Yibing Liu, Wei Wang, Rui Su, Ying Sun, Yibing Huang, Daqian Song, Yanhua Wu, Xinghua Wang. Ratiometric fluorescence and colorimetric dual-mode sensing platform based on carbon dots for detecting copper(II) ions and D-penicillamine.
Analytical and bioanalytical chemistry.
2022 Feb; 414(4):1651-1662. doi:
10.1007/s00216-021-03789-4. [PMID: 34988586] - Parinaz Abdollahiyan, Hassan Heidari, Soheila Hassanzadeh, Mohammad Hasanzadeh, Farzad Seidi, Paria Pashazadeh-Panahi. Providing multicolor plasmonic patterns with graphene quantum dots functionalized d-penicillamine for visual recognition of V(V), Cu (II), and Fe(III): Colorimetric fingerprints of GQDs-DPA for discriminating ions in human urine samples.
Journal of molecular recognition : JMR.
2021 12; 34(12):e2936. doi:
10.1002/jmr.2936. [PMID: 34505710] - Vijay Kumar, Anand Prakash Singh, Nicholas Wheeler, Cristi L Galindo, Jong-Joo Kim. Safety profile of D-penicillamine: a comprehensive pharmacovigilance analysis by FDA adverse event reporting system.
Expert opinion on drug safety.
2021 Nov; 20(11):1443-1450. doi:
10.1080/14740338.2021.1956460. [PMID: 34259127] - Kosar Sadinejad, Arezoo Mirzaie, Paria Pashazadeh-Panahi, Mohammad Hasanzadeh. Sensitive recognition of ractopamine using GQDs-DPA as organic fluorescent probe.
Journal of molecular recognition : JMR.
2021 10; 34(10):e2903. doi:
10.1002/jmr.2903. [PMID: 33970548] - Lingyuan Liu, Qianyi Zhang, Feng Li, Mei Wang, Jing Sun, Shuyun Zhu. Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2021 May; 253(?):119584. doi:
10.1016/j.saa.2021.119584. [PMID: 33636492] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Caroline Prot-Bertoye, Michel Daudon, Isabelle Tostivint, Marie-Paule Dousseaux, Jérôme Defazio, Olivier Traxer, Bertrand Knebelmann, Marie Courbebaisse. [Cystinuria].
Nephrologie & therapeutique.
2021 Apr; 17S(?):S100-S107. doi:
10.1016/j.nephro.2020.03.001. [PMID: 33910689] - C K Ghosh, S A Miah, M A Hasan, M Chowdhury, A R Miah. Prolonged Jaundice in a Patient with Coexisting Hepatitis A Virus Infection and Wilson's Disease.
Mymensingh medical journal : MMJ.
2021 Apr; 30(2):559-561. doi:
NULL. [PMID: 33830143] - Fei Qu, Yanan Chen, Dafeng Jiang, Xian-En Zhao. pH-modulated aggregation-induced emission of Au/Cu nanoclusters and its application to the determination of urea and dissolved ammonia.
Mikrochimica acta.
2021 03; 188(4):113. doi:
10.1007/s00604-021-04770-9. [PMID: 33677619] - Atchariya Chanpong, Anil Dhawan. Long-Term Urinary Copper Excretion on Chelation Therapy in Children with Wilson Disease.
Journal of pediatric gastroenterology and nutrition.
2021 02; 72(2):210-215. doi:
10.1097/mpg.0000000000002982. [PMID: 33369596] - Renee Proost, David Cassiman, Elena Levtchenko, Eva Morava-Kozicz, Jef Neirynck, Peter Witters. Fulminant Wilson Disease in Children: Recovery After Plasma Exchange Without Transplantation.
Journal of pediatric gastroenterology and nutrition.
2020 12; 71(6):720-725. doi:
10.1097/mpg.0000000000002894. [PMID: 32804913] - Maria Tampaki, Nikolaos K Gatselis, Spyridon Savvanis, Emmanouil Koullias, Asterios Saitis, Stella Gabeta, Melanie Deutsch, Emmanouil Manesis, Georgios N Dalekos, John Koskinas. Wilson disease: 30-year data on epidemiology, clinical presentation, treatment modalities and disease outcomes from two tertiary Greek centers.
European journal of gastroenterology & hepatology.
2020 12; 32(12):1545-1552. doi:
10.1097/meg.0000000000001670. [PMID: 32118851] - Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue.
Archives of toxicology.
2020 12; 94(12):4037-4041. doi:
10.1007/s00204-020-02869-1. [PMID: 32808185] - Andreas F Lehner, Levent Dirikolu, Margaret Johnson, John P Buchweitz, Daniel K Langlois. Liquid chromatography/tandem mass spectrometric analysis of penicillamine for its pharmacokinetic evaluation in dogs.
Toxicology mechanisms and methods.
2020 Nov; 30(9):687-702. doi:
10.1080/15376516.2020.1814467. [PMID: 32854553] - Xiao-Qun Zhu, Liang-Yong Li, Wen-Ming Yang, Yu Wang. Combined dimercaptosuccinic acid and zinc treatment in neurological Wilson's disease patients with penicillamine-induced allergy or early neurological deterioration.
Bioscience reports.
2020 08; 40(8):. doi:
10.1042/bsr20200654. [PMID: 32809015] - Jing Zhang, Lulu Xiao, Wenming Yang. Combined sodium Dimercaptopropanesulfonate and zinc versus D-penicillamine as first-line therapy for neurological Wilson's disease.
BMC neurology.
2020 Jun; 20(1):255. doi:
10.1186/s12883-020-01827-9. [PMID: 32593295] - Xiangxue Zhou, Xia Xiao, Xun-Hua Li, Hao-Ling Qin, Xiao-Yong Pu, Ding-Bang Chen, Chao Wu, Li Feng, Xiu-Ling Liang. A study of susceptibility-weighted imaging in patients with Wilson disease during the treatment of metal chelator.
Journal of neurology.
2020 Jun; 267(6):1643-1650. doi:
10.1007/s00415-020-09746-y. [PMID: 32060651] - Xiong Zhang, Qiao Liu, Zong-Wen Wang, Hui Xu, Feng-Ping An, Qun Huang, Hong-Bo Song, Yi-Wei Wang. D-penicillamine modified copper nanoparticles for fluorometric determination of histamine based on aggregation-induced emission.
Mikrochimica acta.
2020 05; 187(6):329. doi:
10.1007/s00604-020-04271-1. [PMID: 32405710] - Paria Pashazadeh-Panahi, Mohammad Hasanzadeh, Reza Eivazzadeh-Keihan. A novel optical probe based on d-penicillamine-functionalized graphene quantum dots: Preparation and application as signal amplification element to minoring of ions in human biofluid.
Journal of molecular recognition : JMR.
2020 05; 33(5):e2828. doi:
10.1002/jmr.2828. [PMID: 32102110] - Qi Wang, Lingfang Li, Tingxuan Wu, Xiangpeng Kong, Qingguo Ma, Chunlei Ma. A graphene quantum dots-Pb2+ based fluorescent switch for selective and sensitive determination of D-penicillamine.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Mar; 229(?):117924. doi:
10.1016/j.saa.2019.117924. [PMID: 31839577] - Marcia Leung, Jaimie Wu Lanzafame, Valentina Medici. Switching Pharmacological Treatment in Wilson Disease: Case Report and Recommendations.
Journal of investigative medicine high impact case reports.
2020 Jan; 8(?):2324709619896876. doi:
10.1177/2324709619896876. [PMID: 31920114] - Maria C Fernandez, Alex Yu, Adel R Moawad, Cristian O'Flaherty. Peroxiredoxin 6 regulates the phosphoinositide 3-kinase/AKT pathway to maintain human sperm viability.
Molecular human reproduction.
2019 12; 25(12):787-796. doi:
10.1093/molehr/gaz060. [PMID: 31651026] - Caroline Prot-Bertoye, Saïd Lebbah, Michel Daudon, Isabelle Tostivint, Jean-Philippe Jais, Agnés Lillo-Le Louët, Clément Pontoizeau, Pierre Cochat, Pierre Bataille, Franck Bridoux, Pierre Brignon, Christian Choquenet, Christian Combe, Pierre Conort, Stéphane Decramer, Bertrand Doré, Bertrand Dussol, Marie Essig, Marie Frimat, Nicolas Gaunez, Dominique Joly, Sophie Le Toquin-Bernard, Arnaud Méjean, Paul Meria, Denis Morin, Hung V N'Guyen, Michel Normand, Michel Pietak, Pierre Ronco, Christian Saussine, Michel Tsimaratos, Gérard Friedlander, Olivier Traxer, Bertrand Knebelmann, Marie Courbebaisse. Adverse events associated with currently used medical treatments for cystinuria and treatment goals: results from a series of 442 patients in France.
BJU international.
2019 11; 124(5):849-861. doi:
10.1111/bju.14721. [PMID: 30801923] - Chunlei Ma, Wensheng Ren, Jianke Tang, Xiaoli Wang, Dongxin Ji, Rongqian Meng, Cuihong Zhang, Qi Wang. Copper nanocluster-based fluorescence enhanced determination of d-penicillamine.
Luminescence : the journal of biological and chemical luminescence.
2019 Nov; 34(7):767-773. doi:
10.1002/bio.3672. [PMID: 31267664] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Heba Helmy, Mona Fahmy, Hanan Abdel Aziz, Carolyne Ghobrial, Nehal Abdel Hameed, Hanaa El-Karaksy. Urinary abnormalities in children and adolescents with Wilson disease before and during treatment with d-penicillamine.
Journal of gastroenterology and hepatology.
2019 Oct; 34(10):1824-1828. doi:
10.1111/jgh.14653. [PMID: 30861190] - Olcay Güngör, Ahmet Kağan Özkaya, Serkan Kirik, Tahir Dalkiran, Gülay Güngör, Sedat Işikay, Mehmet Davutoğlu, Cengiz Dilber. Acute Mercury Poisoning in a Group of School Children.
Pediatric emergency care.
2019 Oct; 35(10):696-699. doi:
10.1097/pec.0000000000001011. [PMID: 27977534] - Norikazu Shimizu. [Diagnosis and treatment of Wilson disease in Japan].
Rinsho shinkeigaku = Clinical neurology.
2019 Sep; 59(9):565-569. doi:
10.5692/clinicalneurol.cn-001241. [PMID: 31474637] - Sena Kang, Myung Hyun Cho, Hyesun Hyun, Ji Hyun Kim, Jae Sung Ko, Hee Gyung Kang, Hae Il Cheong, Woo Sun Kim, Kyung Chul Moon, Il Soo Ha. A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome.
Journal of Korean medical science.
2019 Jun; 34(24):e173. doi:
10.3346/jkms.2019.34.e173. [PMID: 31222986] - Shujuan Ma, Luwei Zhang, Shuyue Wang, Haiyang Zhang, Xin You, Junjie Ou, Mingliang Ye, Yinmao Wei. Preparation of epoxy-functionalized hierarchically porous hybrid monoliths via free radical polymerization and application in HILIC enrichment of glycopeptides.
Analytica chimica acta.
2019 Jun; 1058(?):97-106. doi:
10.1016/j.aca.2019.01.011. [PMID: 30851859] - Jakob Damsgaard, Fin Stolze Larsen, Henriette Ytting. Reversal of Acute Liver Failure Due to Wilson Disease by a Regimen of High-Volume Plasma Exchange and Penicillamine.
Hepatology (Baltimore, Md.).
2019 04; 69(4):1835-1837. doi:
10.1002/hep.30323. [PMID: 30357869] - Jan Pfeiffenberger, Christine Marie Lohse, Daniel Gotthardt, Christian Rupp, Markus Weiler, Ulrike Teufel, Karl Heinz Weiss, Annika Gauss. Long-term evaluation of urinary copper excretion and non-caeruloplasmin associated copper in Wilson disease patients under medical treatment.
Journal of inherited metabolic disease.
2019 03; 42(2):371-380. doi:
10.1002/jimd.12046. [PMID: 30746719] - Longgen Liu, Qing Gong, Juan Liu, Hongyu Shen, Hongyu Zhang, Yuan Xue. Plasma transfusion combined with chelating therapy alleviates fulminant Wilson's disease with a single Arg778Leu heterozygote mutation.
Annals of hepatology.
2019 Mar; 18(2):393-396. doi:
10.1016/j.aohep.2018.07.001. [PMID: 31010795] - Hajime Asada, Mari Kojima, Takuro Nagahara, Yuko Goto-Koshino, James K Chambers, Taisuke Nakagawa, Nozomu Yokoyama, Kazuyuki Uchida, Hajime Tsujimoto, Koichi Ohno. Hepatic copper accumulation in a young cat with familial variations in the ATP7B gene.
Journal of veterinary internal medicine.
2019 Mar; 33(2):874-878. doi:
10.1111/jvim.15399. [PMID: 30561139] - Xiao Lian, Bing Yan. Diagnosis of penicillin allergy: a MOFs-based composite hydrogel for detecting β-lactamase in serum.
Chemical communications (Cambridge, England).
2018 Dec; 55(2):241-244. doi:
10.1039/c8cc08245f. [PMID: 30534686] - Bettina P Mihalas, Elizabeth G Bromfield, Jessie M Sutherland, Geoffry N De Iuliis, Eileen A McLaughlin, R John Aitken, Brett Nixon. Oxidative damage in naturally aged mouse oocytes is exacerbated by dysregulation of proteasomal activity.
The Journal of biological chemistry.
2018 12; 293(49):18944-18964. doi:
10.1074/jbc.ra118.005751. [PMID: 30305393] - Yifan Chen, Juan Qiao, Qianrong Liu, Mingming Zhang, Li Qi. Fluorescence turn-on assay for detection of serum D-penicillamine based on papain@AuNCs-Cu2+ complex.
Analytica chimica acta.
2018 Oct; 1026(?):133-139. doi:
10.1016/j.aca.2018.04.014. [PMID: 29852989] - Julia Wattacheril, Patrick R Shea, Saeed Mohammad, Cynthia Behling, Vimla Aggarwal, Laura A Wilson, Katherine P Yates, Joy Ito, Mark Fishbein, Nicholas Stong, Joel E Lavine, David B Goldstein. Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease.
Cold Spring Harbor molecular case studies.
2018 10; 4(5):. doi:
10.1101/mcs.a003087. [PMID: 30026388] - Maryam Shahrajabian, Forough Ghasemi, M Reza Hormozi-Nezhad. Nanoparticle-based Chemiluminescence for Chiral Discrimination of Thiol-Containing Amino Acids.
Scientific reports.
2018 09; 8(1):14011. doi:
10.1038/s41598-018-32416-z. [PMID: 30228291] - Cesare M Scoffone, Cecilia M Cracco. Pediatric calculi: cause, prevention and medical management.
Current opinion in urology.
2018 09; 28(5):428-432. doi:
10.1097/mou.0000000000000520. [PMID: 29901459] - Maria A Montesu, Giuliana Onnis, Susanna Gunnella, Amelia Lissia, Rosanna Satta. Elastosis perforans serpiginosa: causes and associated disorders.
European journal of dermatology : EJD.
2018 Aug; 28(4):476-481. doi:
10.1684/ejd.2018.3355. [PMID: 30129530] - Huan Yu, Xinfeng Chen, Long Yu, Mingtai Sun, Khalid A Alamry, Abdullah M Asiri, Kui Zhang, Juan Antonio Zapien, Suhua Wang. Fluorescent MUA-stabilized Au nanoclusters for sensitive and selective detection of penicillamine.
Analytical and bioanalytical chemistry.
2018 Apr; 410(10):2629-2636. doi:
10.1007/s00216-018-0936-7. [PMID: 29428990] - Anna Bizoń, Halina Milnerowicz. The effect of divalent metal chelators and cadmium on serum phosphotriesterase, lactonase and arylesterase activities of paraoxonase 1.
Environmental toxicology and pharmacology.
2018 Mar; 58(?):77-83. doi:
10.1016/j.etap.2017.12.019. [PMID: 29306821] - Laura Fumagalli, Lucia Pucciarini, Luca Regazzoni, Ettore Gilardoni, Marina Carini, Giulio Vistoli, Giancarlo Aldini, Roccardo Sardella. Direct HPLC separation of carnosine enantiomers with two chiral stationary phases based on penicillamine and teicoplanin derivatives.
Journal of separation science.
2018 Mar; 41(6):1240-1246. doi:
10.1002/jssc.201701308. [PMID: 29230946] - Piyush Gupta, Mehul Choksi, Ashish Goel, Uday Zachariah, Kattiparambil Gangadharan Sajith, Jeyamani Ramachandran, George Chandy, George Kurian, Grace Rebekah, Chundamannil Eapen Eapen. Maintenance zinc therapy after initial penicillamine chelation to treat symptomatic hepatic Wilson's disease in resource constrained setting.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology.
2018 01; 37(1):31-38. doi:
10.1007/s12664-018-0829-x. [PMID: 29457214] - Carlos Ricardo Maneck Malfatti, Fabio Seidel Dos Santos, Jéssica Wouk, Luiz Augusto da Silva, Renan Garcia Michel, André Luiz Snak, Tiago Czervinski, Mário A Alves da Cunha, Aneli M Barbosa, Robert F H Dekker. Intracerebroventricular administration of the (1→6)-β-d-glucan (lasiodiplodan) in male rats prevents d-penicillamine-induced behavioral alterations and lipoperoxidation in the cortex.
Pharmaceutical biology.
2017 Dec; 55(1):1289-1294. doi:
10.1080/13880209.2017.1299767. [PMID: 28274189] - Oliver Hachmöller, Andree Zibert, Hans Zischka, Michael Sperling, Sara Reinartz Groba, Inga Grünewald, Eva Wardelmann, Hartmut H-J Schmidt, Uwe Karst. Spatial investigation of the elemental distribution in Wilson's disease liver after d-penicillamine treatment by LA-ICP-MS.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2017 Dec; 44(?):26-31. doi:
10.1016/j.jtemb.2017.05.008. [PMID: 28965585] - Muhammad Mukhtiar, Syed Umer Jan, Ihsan Ullah, Abid Hussain, Izhar Ullah, Rahman Gul, Essa Ali, Abdul Jabbar, Zulfiqar Hussan Kuthu, Muhammad Wasim, Muhammad Farid Khan. The role of Glutathione, Cysteine and D-Penicillamine in exchanging Palladium and Vanadium metals from albumin metal complex.
Pakistan journal of pharmaceutical sciences.
2017 Nov; 30(6(Supplementary)):2405-2410. doi:
. [PMID: 29188777] - Anna Wiernicka, Maciej Dądalski, Wojciech Jańczyk, Diana Kamińska, Magdalena Naorniakowska, Anna Hüsing-Kabar, Hartmut Schmidt, Piotr Socha. Early Onset of Wilson Disease: Diagnostic Challenges.
Journal of pediatric gastroenterology and nutrition.
2017 11; 65(5):555-560. doi:
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Toxicology and industrial health.
2017 Jun; 33(6):512-518. doi:
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The Veterinary clinics of North America. Small animal practice.
2017 May; 47(3):631-644. doi:
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Mymensingh medical journal : MMJ.
2017 04; 26(2):406-413. doi:
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Genetics and molecular research : GMR.
2017 Mar; 16(1):. doi:
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Molecular human reproduction.
2017 02; 23(2):106-115. doi:
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Clinical toxicology (Philadelphia, Pa.).
2017 Feb; 55(2):97-101. doi:
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South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
2017 Jan; 107(2):112-114. doi:
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Andrology.
2017 01; 5(1):133-145. doi:
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Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001).
2016 Nov; 26(6):825-830. doi:
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Journal of pediatric gastroenterology and nutrition.
2016 05; 62(5):e46. doi:
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Clinical nephrology.
2016 May; 85(5):296-300. doi:
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Electrophoresis.
2016 Feb; 37(4):601-8. doi:
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Reproduction (Cambridge, England).
2016 Feb; 151(2):167-77. doi:
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Oxidative medicine and cellular longevity.
2016; 2016(?):5213532. doi:
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Current neuropharmacology.
2016; 14(4):322-5. doi:
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Neuromolecular medicine.
2015 Dec; 17(4):364-72. doi:
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Journal of pediatric gastroenterology and nutrition.
2015 Dec; 61(6):613-8. doi:
10.1097/mpg.0000000000000926. [PMID: 26230903] - Kessarin Ngamdee, Theerapong Puangmali, Thawatchai Tuntulani, Wittaya Ngeontae. Circular dichroism sensor based on cadmium sulfide quantum dots for chiral identification and detection of penicillamine.
Analytica chimica acta.
2015 Oct; 898(?):93-100. doi:
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Functional neurology.
2015 Oct; 30(4):264-8. doi:
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Animal reproduction science.
2015 Aug; 159(?):155-62. doi:
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Neurotoxicology.
2015 Jul; 49(?):45-9. doi:
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Biochemical and biophysical research communications.
2015 Feb; 458(1):82-5. doi:
10.1016/j.bbrc.2015.01.071. [PMID: 25634697] - Peng Wang, Bang Lin Li, Nian Bing Li, Hong Qun Luo. A fluorescence detection of D-penicillamine based on Cu(2+)-induced fluorescence quenching system of protein-stabilized gold nanoclusters.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2015 Jan; 135(?):198-202. doi:
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PloS one.
2015; 10(4):e0119654. doi:
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Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2015; 31(?):188-92. doi:
10.1016/j.jtemb.2014.04.010. [PMID: 24894443] - Benzeeta Pinto, Palvi Goyal, S J S Flora, K D Gill, Surjit Singh. Chronic arsenic poisoning following ayurvedic medication.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2014 Dec; 10(4):395-8. doi:
10.1007/s13181-014-0389-0. [PMID: 24696169] - Dragan Krstić, Jadranka Antonijević, Željko Špirić. Atypical case of Wilson's disease with psychotic onset, low 24 hour urine copper and the absence of Kayser-Fleischer rings.
Vojnosanitetski pregled.
2014 Dec; 71(12):1155-8. doi:
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Mayo Clinic proceedings.
2014 Dec; 89(12):e123-7. doi:
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Bioelectrochemistry (Amsterdam, Netherlands).
2014 Oct; 99(?):53-6. doi:
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Journal of medical case reports.
2014 Aug; 8(?):266. doi:
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Biopharmaceutics & drug disposition.
2014 Jul; 35(5):284-95. doi:
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Likars'ka sprava.
2014 Jul; ?(7-8):89-93. doi:
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Mymensingh medical journal : MMJ.
2014 Jul; 23(3):489-95. doi:
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2014 May; 55(5):845-51. doi:
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Veterinary journal (London, England : 1997).
2014 Mar; 199(3):429-33. doi:
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In vitro cellular & developmental biology. Animal.
2014 Jan; 50(1):39-47. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2014 Jan; 137(1):189-211. doi:
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Pakistan journal of pharmaceutical sciences.
2013 Nov; 26(6):1267-70. doi:
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Anaesthesia and intensive care.
2013 Nov; 41(6):811-2. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
2013 Oct; 62(4):806-9. doi:
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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.
2013 Oct; 33(5):743-747. doi:
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Journal of veterinary internal medicine.
2013 Sep; 27(5):1071-6. doi:
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