Classification Term: 170103

含硫氨基酸衍生物 (ontology term: cb0a4280ead9b946536040a925fa38ff)

found 1 associated metabolites at no_class-level_20 metabolite taxonomy ontology rank level.

Ancestor: 氨基酸衍生物

Child Taxonomies: There is no child term of current ontology term.

Penicillamine

D-penicillamine

C5H11NO2S (149.051)


An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group. M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01C - Specific antirheumatic agents > M01CC - Penicillamine and similar agents C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C1971 - Angiogenesis Activator Inhibitor D064449 - Sequestering Agents > D002614 - Chelating Agents D020011 - Protective Agents > D000931 - Antidotes D018501 - Antirheumatic Agents Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine increases free copper and enhances oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria[1][2][3][4].