AI3-35128 (BioDeep_00000865951)

Main id: BioDeep_00000001092

 

PANOMIX_OTCML-2023


代谢物信息卡片


4-01-00-02098 (Beilstein Handbook Reference)

化学式: C6H10S2 (146.0224)
中文名称: 二烯丙基二硫化物, 烯丙基二硫
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CCSSCC=C
InChI: InChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2

描述信息

D009676 - Noxae > D000988 - Antispermatogenic Agents > D013089 - Spermatocidal Agents
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D020011 - Protective Agents > D016587 - Antimutagenic Agents
D000970 - Antineoplastic Agents
Diallyl disulfide inhibits human squalene monooxygenase with an IC50 of 400 μM for squalene epoxidation[1].
Diallyl disulfide inhibits human squalene monooxygenase with an IC50 of 400 μM for squalene epoxidation[1].

同义名列表

40 个代谢物同义名

4-01-00-02098 (Beilstein Handbook Reference); 3-(prop-2-en-1-yldisulfanyl)prop-1-ene; 3-prop-2-enyldisulfanylprop-1-ene; 3,3-disulfanediylbis(prop-1-ene); 3-(Allyldisulfanyl)-1-propene; 3-allyldisulfanylprop-1-ene; 3,3-dithiobis(prop-1-ene); Disulfide, di-2-propenyl; Di(2-propenyl) disulfide; 4,5-Dithia-1,7-octadiene; 2-Propenyl disulphide; 2-Propenyl disulfide; diallyl disulphide; Diallyl disulfide; Allyl disulphide; EINECS 218-548-6; W202800_ALDRICH; SPECTRUM1505174; NCGC00095294-02; allyl disulfide; NCGC00095294-01; 317691_ALDRICH; FEMA No. 2028; NCI60_002410; ZINC01531082; 32621_FLUKA; AIDS-005092; BRN 1699241; AIDS005092; CHEBI:4488; CCRIS 6290; 2179-57-9; AI3-35128; NSC 29228; NSC29228; HSDB 595; diAllS2; C08369; Diallyl disulfide; Diallyl disulfide



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AKT1, ANXA5, BCL2, CASP3, CASP9, CAT, CDKN1A, HPGDS, MAPK14, MAPK8, MSMP, NFE2L2, PIK3C3, PTGS2
Peripheral membrane protein 2 ANXA5, PTGS2
Endoplasmic reticulum membrane 4 BCL2, HMGCR, HMOX1, PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 10 AKT1, BCL2, CASP3, CASP9, CDKN1A, HMOX1, MAPK14, MAPK8, NFE2L2, PCNA
autophagosome 1 PIK3C3
cytosol 14 AKT1, ANXA5, BCL2, CASP3, CASP9, CAT, CDKN1A, GSR, HMOX1, HPGDS, MAPK14, MAPK8, NFE2L2, PIK3C3
nuclear body 2 CDKN1A, PCNA
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 2 NFE2L2, PCNA
nucleoplasm 9 AKT1, CASP3, CDKN1A, HMOX1, HPGDS, MAPK14, MAPK8, NFE2L2, PCNA
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 2 AKT1, TNF
Cytoplasmic side 1 HMOX1
lamellipodium 1 AKT1
Multi-pass membrane protein 1 HMGCR
Synapse 1 MAPK8
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 4 AKT1, CASP3, MAPK14, PIK3C3
Golgi apparatus 1 NFE2L2
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 NFE2L2
endosome 1 PIK3C3
plasma membrane 3 AKT1, NFE2L2, TNF
Membrane 7 AKT1, ANXA5, BCL2, CAT, HMGCR, HMOX1, PIK3C3
axon 1 MAPK8
caveola 1 PTGS2
extracellular exosome 4 ANXA5, CAT, GSR, PCNA
endoplasmic reticulum 4 BCL2, HMGCR, HMOX1, PTGS2
extracellular space 4 HMOX1, IL6, MSMP, TNF
perinuclear region of cytoplasm 2 CDKN1A, HMOX1
mitochondrion 5 BCL2, CASP9, CAT, GSR, MAPK14
protein-containing complex 6 AKT1, BCL2, CASP9, CAT, CDKN1A, PTGS2
intracellular membrane-bounded organelle 2 CAT, HPGDS
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Secreted 2 IL6, MSMP
extracellular region 5 ANXA5, CAT, IL6, MAPK14, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 2 CAT, GSR
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 ANXA5, GSR, TNF
microtubule cytoskeleton 1 AKT1
nucleolus 1 CDKN1A
midbody 1 PIK3C3
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 2 ANXA5, CAT
spindle 1 AKT1
GABA-ergic synapse 1 PIK3C3
Peroxisome 2 CAT, PIK3C3
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 2 CAT, HMGCR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ANXA5
axoneme 1 PIK3C3
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 NFE2L2, PCNA
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
spindle pole 1 MAPK14
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
replication fork 1 PCNA
myelin sheath 1 BCL2
Peroxisome membrane 1 HMGCR
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 2 CAT, MAPK14
endoplasmic reticulum lumen 2 IL6, PTGS2
male germ cell nucleus 1 PCNA
presynaptic endosome 1 PIK3C3
Single-pass type IV membrane protein 1 HMOX1
apoptosome 1 CASP9
vesicle membrane 1 ANXA5
nuclear lamina 1 PCNA
protein-DNA complex 1 NFE2L2
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
cyclin-dependent protein kinase holoenzyme complex 2 CDKN1A, PCNA
postsynaptic endosome 1 PIK3C3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 PIK3C3
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
PCNA complex 1 PCNA
PCNA-p21 complex 2 CDKN1A, PCNA
replisome 1 PCNA
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Zeinab Farhat, Tyler Scheving, Diana S Aga, Pamela A Hershberger, Jo L Freudenheim, Rachael Hageman Blair, Manoj J Mammen, Lina Mu. Antioxidant and Antiproliferative Activities of Several Garlic Forms. Nutrients. 2023 Sep; 15(19):. doi: 10.3390/nu15194099. [PMID: 37836382]
  • Jiaqi Zhu, Fu Wang, Youjun Zhang, Yuting Yang, Dengke Hua. Odorant-binding Protein 10 From Bradysia odoriphaga (Diptera: Sciaridae) Binds Volatile Host Plant Compounds. Journal of insect science (Online). 2023 Jan; 23(1):. doi: 10.1093/jisesa/iead004. [PMID: 36729094]
  • Muhammad Ali, Husain Ahmad, Bakht Amin, Muhammad Jawaad Atif, Zhihui Cheng. Induce defense response of DADS in eggplants during the biotrophic phase of Verticillium dahliae. BMC plant biology. 2022 Apr; 22(1):172. doi: 10.1186/s12870-022-03527-7. [PMID: 35379184]
  • Fan Yang, Hui Wang, Chengchen Zhi, Birong Chen, Yujie Zheng, Lijun Qiao, Jingcao Gao, Yupeng Pan, Zhihui Cheng. Garlic Volatile Diallyl Disulfide Induced Cucumber Resistance to Downy Mildew. International journal of molecular sciences. 2021 Nov; 22(22):. doi: 10.3390/ijms222212328. [PMID: 34830208]
  • Syed Mohammed Basheeruddin Asdaq, Abdulhakeem S Alamri, Walaa F Alsanie, Majid Alhomrani. Cardioprotective Potential of Garlic Oil and Its Active Constituent, Diallyl Disulphide, in Presence of Carvedilol during Chronic Isoprenaline Injection-Mediated Myocardial Necrosis in Rats. Molecules (Basel, Switzerland). 2021 Aug; 26(17):. doi: 10.3390/molecules26175137. [PMID: 34500571]
  • Muhammad Ali, Husain Ahmad, Sikandar Hayat, Muhammad Imran Ghani, Bakht Amin, Muhammad Jawaad Atif, Kashif Wali, Zhihui Cheng. Application of garlic allelochemicals improves growth and induces defense responses in eggplant (Solanum melongena) against Verticillium dahliae. Ecotoxicology and environmental safety. 2021 Jun; 215(?):112132. doi: 10.1016/j.ecoenv.2021.112132. [PMID: 33743403]
  • Emad H M Hassanein, Wafaa R Mohamed, Marwa M Khalaf, Abdel-Gawad S Shalkami, Ahmed M Sayed, Ramadan A M Hemeida. Diallyl disulfide ameliorates methotrexate-induced nephropathy in rats: Molecular studies and network pharmacology analysis. Journal of food biochemistry. 2021 06; 45(6):e13765. doi: 10.1111/jfbc.13765. [PMID: 33997994]
  • Haiyan He, Yaoying Ma, Huaxing Huang, Chao Huang, Zhuo Chen, Dongjian Chen, Yiming Gu, Xiaohua Wang, Jinliang Chen. A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities. European journal of pharmacology. 2021 Feb; 893(?):173803. doi: 10.1016/j.ejphar.2020.173803. [PMID: 33359648]
  • Ya-Ru Wu, Liang Li, Xian-Chang Sun, Jun Wang, Chun-Yan Ma, Yue Zhang, Hui-Lin Qu, Rui-Xia Xu, Jian-Jun Li. Diallyl disulfide improves lipid metabolism by inhibiting PCSK9 expression and increasing LDL uptake via PI3K/Akt-SREBP2 pathway in HepG2 cells. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2021 01; 31(1):322-332. doi: 10.1016/j.numecd.2020.08.012. [PMID: 33500108]
  • Chenghao Lv, Caiqiong Wang, Ping Li, Yiwen Huang, Xiangyang Lu, Meng Shi, Chaoxi Zeng, Si Qin. Effect of Garlic Organic Sulfides on Gene Expression Profiling in HepG2 Cells and Its Biological Function Analysis by Ingenuity Pathway Analysis System and Bio-Plex-Based Assays. Mediators of inflammation. 2021; 2021(?):7681252. doi: 10.1155/2021/7681252. [PMID: 34887701]
  • Wanchao Hu, Liou Huang, Ziyang Zhou, Liping Yin, Jianguo Tang. Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice. Frontiers in cellular and infection microbiology. 2021; 11(?):743454. doi: 10.3389/fcimb.2021.743454. [PMID: 35071031]
  • You Jeong Lee, Song-Hyun Cha, Hyunjo Kim, Sung Eun Choi, Seonho Cho, Youmie Park. Diallyl disulphide-loaded spherical gold nanoparticles and acorn-like silver nanoparticles synthesised using onion extract: catalytic activity and cytotoxicity. Artificial cells, nanomedicine, and biotechnology. 2020 Dec; 48(1):948-960. doi: 10.1080/21691401.2020.1773485. [PMID: 32496831]
  • Fang Cheng, Muhammad Ali, Ce Liu, Rui Deng, Zhihui Cheng. Garlic Allelochemical Diallyl Disulfide Alleviates Autotoxicity in the Root Exudates Caused by Long-Term Continuous Cropping of Tomato. Journal of agricultural and food chemistry. 2020 Oct; 68(42):11684-11693. doi: 10.1021/acs.jafc.0c03894. [PMID: 32991155]
  • Suzan M Hazzaa, Seham Ahmed Mohamed Abdelaziz, Mabrouk A Abd Eldaim, Mohamed M Abdel-Daim, Ghada E Elgarawany. Neuroprotective Potential of Allium sativum against Monosodium Glutamate-Induced Excitotoxicity: Impact on Short-Term Memory, Gliosis, and Oxidative Stress. Nutrients. 2020 Apr; 12(4):. doi: 10.3390/nu12041028. [PMID: 32290031]
  • Xing Xu, Peili Hu, Yaoying Ma, Lijuan Tong, Dan Wang, Yue Wu, Zhuo Chen, Chao Huang. Identification of a pro-elongation effect of diallyl disulfide, a major organosulfur compound in garlic oil, on microglial process. The Journal of nutritional biochemistry. 2020 04; 78(?):108323. doi: 10.1016/j.jnutbio.2019.108323. [PMID: 32135404]
  • Marimuthu Mathan Kumar, Ramasamy Tamizhselvi. Protective effect of diallyl disulfide against cerulein-induced acute pancreatitis and associated lung injury in mice. International immunopharmacology. 2020 Mar; 80(?):106136. doi: 10.1016/j.intimp.2019.106136. [PMID: 31991372]
  • Hongxing Zhang, Chi Shang, Zhao Tian, Hatem K Amin, Rami B Kassab, Ahmed E Abdel Moneim, Yingang Zhang. Diallyl Disulfide Suppresses Inflammatory and Oxidative Machineries following Carrageenan Injection-Induced Paw Edema in Mice. Mediators of inflammation. 2020; 2020(?):8508906. doi: 10.1155/2020/8508906. [PMID: 32377166]
  • Jie Sun, Baoguo Sun, Fazheng Ren, Haitao Chen, Ning Zhang, Yuyu Zhang. Influence of Different Frying Processes on the Flavor Characteristics and Sensory Profile of Garlic Oil. Molecules (Basel, Switzerland). 2019 Dec; 24(24):. doi: 10.3390/molecules24244456. [PMID: 31817376]
  • Yanhong Yang, Fei Yang, Miaoling Huang, Huijuan Wu, Changyuan Yang, Xinyue Zhang, Lanxiang Yang, Guibin Chen, Shuqi Li, Qianyu Wang, Shaomin Liu, Yanyan Liu, Yuting Lei, Zili Lei, Jiao Guo. Fatty liver and alteration of the gut microbiome induced by diallyl disulfide. International journal of molecular medicine. 2019 Nov; 44(5):1908-1920. doi: 10.3892/ijmm.2019.4350. [PMID: 31573042]
  • Yaochen Wang, Keke Wei, Xiaobin Han, Donglin Zhao, Yanfen Zheng, Jianmin Chao, Jianyu Gou, Fanyu Kong, Cheng-Sheng Zhang. The Antifungal Effect of Garlic Essential Oil on Phytophthora nicotianae and the Inhibitory Component Involved. Biomolecules. 2019 10; 9(10):. doi: 10.3390/biom9100632. [PMID: 31640228]
  • Chen-Hsin Kuo, Yann-Lii Leu, Tong-Hong Wang, Wei-Che Tseng, Chun-Hao Feng, Shu-Huei Wang, Chin-Chuan Chen. A novel DNA repair inhibitor, diallyl disulfide (DADS), impairs DNA resection during DNA double-strand break repair by reducing Sae2 and Exo1 levels. DNA repair. 2019 10; 82(?):102690. doi: 10.1016/j.dnarep.2019.102690. [PMID: 31479843]
  • Fan Yang, Xiaoxue Liu, Hui Wang, Rui Deng, Hanhan Yu, Zhihui Cheng. Identification and Allelopathy of Green Garlic (Allium sativum L.) Volatiles on Scavenging of Cucumber (Cucumis sativus L.) Reactive Oxygen Species. Molecules (Basel, Switzerland). 2019 Sep; 24(18):. doi: 10.3390/molecules24183263. [PMID: 31500271]
  • Ning Zhang, Yuli Wang, Junli Zhang, Beibei Liu, Guixin Li, Shengliang Xin, Keshu Xu. Diallyl disulfide attenuates non‑alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, lipid peroxidation and inflammation in mice. Molecular medicine reports. 2019 Aug; 20(2):1363-1372. doi: 10.3892/mmr.2019.10316. [PMID: 31173200]
  • Igor A Schepetkin, Liliya N Kirpotina, Andrei I Khlebnikov, Narayanaganesh Balasubramanian, Mark T Quinn. Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds. Molecules (Basel, Switzerland). 2019 May; 24(9):. doi: 10.3390/molecules24091809. [PMID: 31083328]
  • Jaehoon Bae, Motofumi Kumazoe, Yoshinori Fujimura, Hirofumi Tachibana. Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity. The Journal of nutritional biochemistry. 2019 02; 64(?):152-161. doi: 10.1016/j.jnutbio.2018.10.014. [PMID: 30504007]
  • Kaili Ren, Sikandar Hayat, Xiaofang Qi, Tao Liu, Zhihui Cheng. The garlic allelochemical DADS influences cucumber root growth involved in regulating hormone levels and modulating cell cycling. Journal of plant physiology. 2018 Nov; 230(?):51-60. doi: 10.1016/j.jplph.2018.08.007. [PMID: 30170241]
  • Muammer M Şahin, Mehmet B Uğur, Recep Karamert, Sinem Aytekin, Burak Kabiş, Mehmet Düzlü, Cemile Seymen, Çiğdem Elmas, Çağıl Gökdoğan, Serkan Ünlü. Evaluation of Effect of Garlic Aged Extracts and Vitamin B12 on Noise-Induced Hearing Loss. Noise & health. 2018 Nov; 20(97):232-239. doi: 10.4103/nah.nah_33_18. [PMID: 31823910]
  • Kobra Bahrampour Juybari, Tunku Kamarul, Mohammad Najafi, Davood Jafari, Ali Mohammad Sharifi. Restoring the IL-1β/NF-κB-induced impaired chondrogenesis by diallyl disulfide in human adipose-derived mesenchymal stem cells via attenuation of reactive oxygen species and elevation of antioxidant enzymes. Cell and tissue research. 2018 08; 373(2):407-419. doi: 10.1007/s00441-018-2825-y. [PMID: 29582166]
  • Abdel-Tawab H Mossa, Sahar I Afia, Samia M M Mohafrash, Badawi A Abou-Awad. Formulation and characterization of garlic (Allium sativum L.) essential oil nanoemulsion and its acaricidal activity on eriophyid olive mites (Acari: Eriophyidae). Environmental science and pollution research international. 2018 Apr; 25(11):10526-10537. doi: 10.1007/s11356-017-0752-1. [PMID: 29181754]
  • Tae Hoon Kim, Jin-Chul Kim. Redox-responsive solid lipid microparticles composed of octadecyl acrylate and allyl disulfide. Journal of biomaterials science. Polymer edition. 2018 04; 29(5):476-490. doi: 10.1080/09205063.2017.1422854. [PMID: 29291676]
  • Venkata Talluri Siddhartha, Sai Kiran S S Pindiprolu, Pavan Kumar Chintamaneni, Shashank Tummala, S Nandha Kumar. RAGE receptor targeted bioconjuguate lipid nanoparticles of diallyl disulfide for improved apoptotic activity in triple negative breast cancer: in vitro studies. Artificial cells, nanomedicine, and biotechnology. 2018 Mar; 46(2):387-397. doi: 10.1080/21691401.2017.1313267. [PMID: 28415882]
  • Xiaoran Yin, Cheng Feng, Lili Han, Yinan Ma, Yang Jiao, Jun Wang, Lijun Jia, Fuchun Jing, Xiaoyan Gao, Yinbin Zhang, Jun Zhang. Diallyl disulfide inhibits the metastasis of type Ⅱ esophageal‑gastric junction adenocarcinoma cells via NF-κB and PI3K/AKT signaling pathways in vitro. Oncology reports. 2018 Feb; 39(2):784-794. doi: 10.3892/or.2017.6113. [PMID: 29207122]
  • Yuqing Chen, Rong Xue, Xiaochen Jin, Xiangqi Tan. Antiarthritic Activity of Diallyl Disulfide against Freund's Adjuvant-Induced Arthritic Rat Model. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2018; 37(4):291-303. doi: 10.1615/jenvironpatholtoxicoloncol.2018027078. [PMID: 30806236]
  • Xinhua Xie, Xiaojia Huang, Hailin Tang, Feng Ye, Lu Yang, Xiaofang Guo, Zhi Tian, Xiaofang Xie, Cheng Peng, Xiaoming Xie. Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling. Current cancer drug targets. 2018; 18(6):592-599. doi: 10.2174/1568009617666171024165657. [PMID: 29110616]
  • Javier Morales-López, Mónica Centeno-Álvarez, Antonio Nieto-Camacho, Mercedes G López, Elizabeth Pérez-Hernández, Nury Pérez-Hernández, Eduardo Fernández-Martínez. Evaluation of antioxidant and hepatoprotective effects of white cabbage essential oil. Pharmaceutical biology. 2017 Dec; 55(1):233-241. doi: 10.1080/13880209.2016.1258424. [PMID: 27927070]
  • Azam Hosseinzadeh, Davood Jafari, Tunku Kamarul, Abolfazll Bagheri, Ali M Sharifi. Evaluating the Protective Effects and Mechanisms of Diallyl Disulfide on Interlukin-1β-Induced Oxidative Stress and Mitochondrial Apoptotic Signaling Pathways in Cultured Chondrocytes. Journal of cellular biochemistry. 2017 07; 118(7):1879-1888. doi: 10.1002/jcb.25907. [PMID: 28169456]
  • Frank Albrecht, Roman Leontiev, Claus Jacob, Alan J Slusarenko. An Optimized Facile Procedure to Synthesize and Purify Allicin. Molecules (Basel, Switzerland). 2017 May; 22(5):. doi: 10.3390/molecules22050770. [PMID: 28489057]
  • Siddhartha Venkata Talluri, Gowthamarajan Kuppusamy, Veera Venkata Satyanarayana Reddy Karri, Karthik Yamjala, Ashish Wadhwani, SubbaRao V Madhunapantula, Saikiran S S Pindiprolu. Application of quality-by-design approach to optimize diallyl disulfide-loaded solid lipid nanoparticles. Artificial cells, nanomedicine, and biotechnology. 2017 May; 45(3):474-488. doi: 10.3109/21691401.2016.1173046. [PMID: 27112220]
  • Sharon E Mason, Keena A E Mullen, Kevin L Anderson, Steven P Washburn, James L Yeatts, Ronald E Baynes. Pharmacokinetic analysis of thymol, carvacrol and diallyl disulfide after intramammary and topical applications in healthy organic dairy cattle. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2017 May; 34(5):740-749. doi: 10.1080/19440049.2017.1285056. [PMID: 28277182]
  • Hoda S El-Sayed, Remigius Chizzola, Asmaa A Ramadan, Amr E Edris. Chemical composition and antimicrobial activity of garlic essential oils evaluated in organic solvent, emulsifying, and self-microemulsifying water based delivery systems. Food chemistry. 2017 Apr; 221(?):196-204. doi: 10.1016/j.foodchem.2016.10.052. [PMID: 27979186]
  • Je-Won Ko, Jin-Young Shin, Jeong-Won Kim, Sung-Hyeuk Park, Na-Rae Shin, In-Chul Lee, In-Sik Shin, Changjong Moon, Sung-Ho Kim, Sung-Hwan Kim, Jong-Choon Kim. Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: A possible role of CYP2E1 and NF-κB. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2017 Apr; 102(?):156-165. doi: 10.1016/j.fct.2017.02.021. [PMID: 28219698]
  • Fang Cheng, Zhi-Hui Cheng, Huan-Wen Meng. Transcriptomic insights into the allelopathic effects of the garlic allelochemical diallyl disulfide on tomato roots. Scientific reports. 2016 12; 6(?):38902. doi: 10.1038/srep38902. [PMID: 27941943]
  • Yunlong Shan, Zhonghong Wei, Li Tao, Siliang Wang, Feng Zhang, Cunsi Shen, Hongyan Wu, Zhaoguo Liu, Pingting Zhu, Aiyun Wang, Wenxing Chen, Yin Lu. Prophylaxis of Diallyl Disulfide on Skin Carcinogenic Model via p21-dependent Nrf2 stabilization. Scientific reports. 2016 10; 6(?):35676. doi: 10.1038/srep35676. [PMID: 27759091]
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