Citreorosein (BioDeep_00000409551)

Main id: BioDeep_00000011904

 

natural product


代谢物信息卡片


9,10-Anthracenedione, 1,3,8-trihydroxy-6-(hydroxymethyl)-

化学式: C15H10O6 (286.0477)
中文名称: 羟基大黄素
谱图信息: 最多检出来源 Helianthus annuus(natural_products) 15%

分子结构信息

SMILES: C12C(O)=CC(CO)=CC=1C(=O)C1=C(C(O)=CC(O)=C1)C2=O
InChI: InChI=1S/C15H10O6/c16-5-6-1-8-12(10(18)2-6)15(21)13-9(14(8)20)3-7(17)4-11(13)19/h1-4,16-19H,5H2

描述信息

同义名列表

16 个代谢物同义名

Citreorosein; 9,10-Anthracenedione, 1,3,8-trihydroxy-6-(hydroxymethyl)-; 1,3,8-trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione; 1,3,8-Trihydroxy-6-(hydroxymethyl)anthra-9,10-quinone; 1,3,8-trihydroxy-6-methylol-9,10-anthraquinone; 1,3,8-Trihydroxy-6-hydroxymethylanthraquinone; .omega.-hydroxyemodin; omega-Hydroxyemodin; ACon1_001349; AIDS-131771; CCRIS 1319; AIDS131771; NSC624612; 481-73-2; 1,3,8-trihydroxy-6-(hydroxymethyl)-9,10-anthracenedione; Citreorosein



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

65 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CAPN1, CYP1A1, KITLG, MAPK14, MAPK3, MAPK8, PTGS2, SYK, TNK1
Peripheral membrane protein 6 CYP1A1, CYP1B1, GBA1, GORASP1, PTGS2, TNK1
Endoplasmic reticulum membrane 4 CYP1A1, CYP1A2, CYP1B1, PTGS2
Nucleus 7 GABPA, JUN, JUND, MAPK14, MAPK3, MAPK8, SYK
cytosol 5 CAPN1, MAPK14, MAPK3, MAPK8, SYK
trans-Golgi network 1 GBA1
nucleoplasm 6 GABPA, JUN, JUND, MAPK14, MAPK3, MAPK8
RNA polymerase II transcription regulator complex 2 JUN, JUND
Cell membrane 5 CAPN1, KIT, KITLG, SYK, TNF
Cytoplasmic side 1 GORASP1
lamellipodium 1 KITLG
Golgi apparatus membrane 1 GORASP1
Synapse 1 MAPK8
cell surface 1 TNF
glutamatergic synapse 2 MAPK14, MAPK3
Golgi apparatus 3 GBA1, GORASP1, MAPK3
Golgi membrane 1 GORASP1
lysosomal membrane 1 GBA1
mitochondrial inner membrane 1 CYP1A1
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 SYK
Lysosome 3 CAPN1, GBA1, SGSH
acrosomal vesicle 1 KIT
plasma membrane 7 CAPN1, KIT, KITLG, MAPK3, SYK, TNF, TNK1
Membrane 5 CAPN1, CYP1B1, KIT, KITLG, TNK1
axon 1 MAPK8
caveola 2 MAPK3, PTGS2
extracellular exosome 3 CAPN1, GBA1, SGSH
Lysosome membrane 1 GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 2 GBA1, PTGS2
extracellular space 4 IL10, KIT, KITLG, TNF
lysosomal lumen 2 GBA1, SGSH
mitochondrion 5 CAPN1, CYP1A1, CYP1B1, MAPK14, MAPK3
protein-containing complex 2 PTGS2, SYK
intracellular membrane-bounded organelle 3 CYP1A1, CYP1A2, CYP1B1
Microsome membrane 4 CYP1A1, CYP1A2, CYP1B1, PTGS2
filopodium 1 KITLG
Single-pass type I membrane protein 2 KIT, KITLG
Secreted 2 IL10, KITLG
extracellular region 5 CAPN1, IL10, KITLG, MAPK14, TNF
cytoplasmic side of plasma membrane 1 KIT
transcription regulator complex 2 JUN, JUND
external side of plasma membrane 2 KIT, TNF
Early endosome 1 MAPK3
cell-cell junction 1 KIT
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cell projection, lamellipodium 1 KITLG
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 1 TNF
Cell junction, focal adhesion 1 MAPK3
Cytoplasm, cytoskeleton 1 KITLG
focal adhesion 2 CAPN1, MAPK3
cis-Golgi network 1 GORASP1
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, filopodium 1 KITLG
Late endosome 1 MAPK3
receptor complex 1 KIT
neuron projection 1 PTGS2
chromatin 3 GABPA, JUN, JUND
phagocytic cup 1 TNF
cytoskeleton 2 KITLG, MAPK3
spindle pole 1 MAPK14
nuclear chromosome 1 JUN
fibrillar center 1 KIT
nuclear envelope 1 MAPK3
Membrane, caveola 1 MAPK3
Cornified envelope 1 CAPN1
euchromatin 1 JUN
pseudopodium 1 MAPK3
[Isoform 3]: Cytoplasm 1 KIT
ficolin-1-rich granule lumen 2 CAPN1, MAPK14
secretory granule lumen 1 MAPK14
endoplasmic reticulum lumen 2 MAPK3, PTGS2
transcription repressor complex 1 JUND
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
[Isoform 2]: Cytoplasm 1 KITLG
basal dendrite 1 MAPK8
early phagosome 1 SYK
transcription factor AP-1 complex 2 JUN, JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 SYK
calpain complex 1 CAPN1
B cell receptor complex 1 SYK
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Mario Figueroa, Alan K Jarmusch, Huzefa A Raja, Tamam El-Elimat, Jeffrey S Kavanaugh, Alexander R Horswill, R Graham Cooks, Nadja B Cech, Nicholas H Oberlies. Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. Journal of natural products. 2014 Jun; 77(6):1351-8. doi: 10.1021/np5000704. [PMID: 24911880]
  • H Murakami, J Kobayashi, T Masuda, N Morooka, Y Ueno. omega-Hydroxyemodin, a major hepatic metabolite of emodin in various animals and its mutagenic activity. Mutation research. 1987 Oct; 180(2):147-53. doi: 10.1016/0027-5107(87)90209-0. [PMID: 3309636]