Diacetyl (BioDeep_00000405566)

Main id: BioDeep_00000002860

Secondary id: BioDeep_00001867704

PANOMIX_OTCML-2023 BioNovoGene_Lab2019 natural product


代谢物信息卡片


4-01-00-03644 (Beilstein Handbook Reference)

化学式: C4H6O2 (86.0368)
中文名称: 2,3-丁二酮
谱图信息: 最多检出来源 Homo sapiens(feces) 10%

分子结构信息

SMILES: CC(=O)C(=O)C
InChI: InChI=1S/C4H6O2/c1-3(5)4(2)6/h1-2H3

描述信息

同义名列表

53 个代谢物同义名

4-01-00-03644 (Beilstein Handbook Reference); Butanedione [UN2346] [Flammable liquid]; Butanedione [UN2346] [Flammable liquid]; InChI=1\C4H6O2\c1-3(5)4(2)6\h1-2H; 2,3-Butanedione (8CI,9CI); Diacetyl (natural); Glyoxal, dimethyl-; Acetoacetaldehyde; Dimethyl diketone; butane-2,3-dione; EINECS 207-069-8; Dimethyl glyoxal; 2,3-Diketobutane; NCGC00090746-01; NCGC00015336-01; Butanal, 3-oxo-; W237000_ALDRICH; Dimethylglyoxal; 2,3-Dioxobutane; W237035_ALDRICH; 2,3-butanedione; 2,3-Butandione; B85307_ALDRICH; Lopac0_000387; FEMA No. 2370; 2,3-Butadione; ZINC01532732; Lopac-D-3634; 151677-70-2; BRN 0605398; 31530_FLUKA; CHEBI:16583; 11038_FLUKA; Butanedione; EU-0100387; SGCUT00113; WLN: 1VV1; AI3-03313; CCRIS 827; Butadione; to_000005; Diacetyl; HSDB 297; 431-03-8; 625-34-3; NSC 8750; Biacetyl; NSC8750; UN2346; LS-116; C00741; 2,3-Butanedione; Diacetyl



数据库引用编号

23 个数据库交叉引用编号

分类词条

51 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, AXIN2, BDH2, CAT, EGFR, GAPDH, KRT5, MME, POMC, WT1
Peripheral membrane protein 2 ACHE, HSD17B6
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 1 EGFR
Nucleus 7 ACHE, ALB, AXIN2, EGFR, GAPDH, KRT5, WT1
cytosol 8 ALB, AXIN2, BDH2, CAT, GAPDH, KRT5, PGK1, WT1
dendrite 1 MME
trans-Golgi network 1 MME
centrosome 2 ALB, AXIN2
nucleoplasm 2 ATP2B1, WT1
Cell membrane 4 ACHE, ATP2B1, EGFR, MME
ruffle membrane 1 EGFR
Early endosome membrane 2 EGFR, HSD17B6
Multi-pass membrane protein 1 ATP2B1
Synapse 3 ACHE, ATP2B1, MME
cell junction 1 EGFR
cell surface 3 ACHE, EGFR, MME
glutamatergic synapse 2 ATP2B1, EGFR
Golgi apparatus 3 ACHE, ALB, ATRN
Golgi membrane 2 EGFR, INS
mitochondrial inner membrane 1 BDH1
neuromuscular junction 1 ACHE
neuronal cell body 1 MME
presynaptic membrane 1 ATP2B1
synaptic vesicle 1 MME
Cytoplasm, cytosol 1 GAPDH
Presynapse 1 MME
endosome 1 EGFR
plasma membrane 8 ACHE, ATP2B1, ATRN, AXIN2, EGFR, GAPDH, IGHE, MME
synaptic vesicle membrane 1 ATP2B1
Membrane 9 ACHE, ATP2B1, BDH1, CAT, EGFR, GAPDH, KRT5, MME, PGK1
apical plasma membrane 1 EGFR
axon 1 MME
basolateral plasma membrane 2 ATP2B1, EGFR
brush border 1 MME
extracellular exosome 10 ALB, ATP2B1, ATRN, BDH2, CAT, GAPDH, KRT5, LYZ, MME, PGK1
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ALB, HSD17B6
extracellular space 10 ACHE, ALB, ATRN, CXCL8, EGFR, IGHE, INS, LYZ, PGK1, POMC
perinuclear region of cytoplasm 3 ACHE, EGFR, GAPDH
mitochondrion 2 BDH1, CAT
protein-containing complex 3 ALB, CAT, EGFR
intracellular membrane-bounded organelle 5 ATP2B1, BDH1, CAT, GAPDH, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 3 ATRN, EGFR, IGHE
Secreted 5 ACHE, ALB, CXCL8, INS, POMC
extracellular region 8 ACHE, ALB, CAT, CXCL8, IGHE, INS, LYZ, POMC
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 1 BDH1
mitochondrial matrix 2 BDH1, CAT
Extracellular side 1 ACHE
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 2 EGFR, GAPDH
beta-catenin destruction complex 1 AXIN2
cytoplasmic vesicle 1 MME
microtubule cytoskeleton 1 GAPDH
nucleolus 1 WT1
Early endosome 1 MME
Single-pass type II membrane protein 1 MME
vesicle 1 GAPDH
Cytoplasm, perinuclear region 1 GAPDH
Mitochondrion inner membrane 1 BDH1
Membrane raft 3 EGFR, MME, PGK1
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 3 CAT, EGFR, MME
Peroxisome 1 CAT
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 POMC
intermediate filament 1 KRT5
lateral plasma membrane 1 ATP2B1
nuclear speck 1 WT1
receptor complex 1 EGFR
ciliary basal body 1 ALB
IgE immunoglobulin complex 1 IGHE
cell projection 1 ATP2B1
cytoskeleton 1 GAPDH
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 2]: Cell membrane 1 IGHE
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 INS
Lipid droplet 1 GAPDH
Nucleus speckle 1 WT1
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, INS, POMC
secretory granule membrane 1 MME
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 1 ALB
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
transport vesicle 1 INS
azurophil granule lumen 1 LYZ
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
clathrin-coated endocytic vesicle membrane 1 EGFR
ribonucleoprotein complex 1 GAPDH
synaptic cleft 1 ACHE
[Isoform 1]: Cell membrane 1 ATRN
keratin filament 1 KRT5
GAIT complex 1 GAPDH
[Isoform 3]: Cell membrane 1 IGHE
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
catalase complex 1 CAT
neuron projection terminus 1 MME
photoreceptor ribbon synapse 1 ATP2B1
[Isoform 1]: Nucleus speckle 1 WT1
[Isoform 4]: Nucleus, nucleoplasm 1 WT1
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
matrix side of mitochondrial inner membrane 1 BDH1


文献列表

  • Yang Yang, Hai-Ling Wang, Rui-Tong Cheng, Pei-Rong Zheng, Hui-Peng Sun, Zhi-Wen Liu, Heng Yuan, Xue-Yi Liu, Wen-Yun Gao, Heng Li. Determination of α-Dicarbonyl compounds in traditional Chinese herbal medicines. Fitoterapia. 2024 Jun; 175(?):105928. doi: 10.1016/j.fitote.2024.105928. [PMID: 38548027]
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  • Yaping Jiang, Matt Hengel, Canping Pan, James N Seiber, Takayuki Shibamoto. Determination of toxic α-dicarbonyl compounds, glyoxal, methylglyoxal, and diacetyl, released to the headspace of lipid commodities upon heat treatment. Journal of agricultural and food chemistry. 2013 Feb; 61(5):1067-71. doi: 10.1021/jf3047303. [PMID: 23317342]
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