Inosine triphosphate (BioDeep_00000405212)

Main id: BioDeep_00000001622

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


Inosine triphosphate

化学式: C10H15N4O14P3 (507.9798)
中文名称:
谱图信息: 最多检出来源 Mus musculus(not specific) 39.44%

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc[nH]c3=O)O1)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O
InChI: InChI=1S/C10H15N4O14P3/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

描述信息

The inosine phosphate that has a triphosphate group at the 5-position. It is an intermediate in the metabolism of purine.

同义名列表

3 个代谢物同义名

Inosine triphosphate; ITP; ITP



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ADSS2, GCK, GTPBP4, IPP, ITPA, MYLK, NUDT16, SP1, TPMT, XDH
Peripheral membrane protein 1 GCK
Endoplasmic reticulum membrane 2 ENTPD2, GRIN2A
Nucleus 6 GCK, GTPBP4, NUDT16, PLCZ1, SP1, SP3
cytosol 9 ADSS2, GCK, GTPBP4, ITPA, MYLK, PLCZ1, SP3, TPMT, XDH
nucleoplasm 8 CD2, GCK, GTPBP4, ITPA, NUDT16, PLCZ1, SP1, SP3
Cell membrane 5 C5AR1, CD2, GRIN2A, P2RX1, P2RY2
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Multi-pass membrane protein 4 C5AR1, GRIN2A, P2RX1, P2RY2
Golgi apparatus membrane 1 GCK
Synapse 2 GRIN2A, MYLK
cell surface 2 CD2, GRIN2A
glutamatergic synapse 2 GRIN2A, P2RX1
Golgi apparatus 1 CD2
Golgi membrane 1 GCK
postsynapse 1 P2RX1
presynaptic membrane 1 GRIN2A
synaptic vesicle 1 GRIN2A
plasma membrane 8 C5AR1, CD2, ENTPD2, GRIN2A, IFNLR1, MYLK, P2RX1, P2RY2
Membrane 4 GRIN2A, GTPBP4, IFNLR1, P2RX1
basolateral plasma membrane 2 C5AR1, GCK
extracellular exosome 2 ADSS2, ENTPD2
endoplasmic reticulum 1 GRIN2A
extracellular space 3 IFNL3, SP1, XDH
perinuclear region of cytoplasm 2 GTPBP4, PLCZ1
mitochondrion 2 ADSS2, GCK
protein-containing complex 2 CD2, P2RX1
intracellular membrane-bounded organelle 1 ITPA
postsynaptic density 1 GRIN2A
pronucleus 1 PLCZ1
Single-pass type I membrane protein 2 CD2, IFNLR1
Secreted 2 IFNL3, SP1
extracellular region 3 CD2, IFNL3, SP1
cytoplasmic side of plasma membrane 1 CD2
nuclear membrane 1 GTPBP4
external side of plasma membrane 2 CD2, P2RX1
actin cytoskeleton 2 IPP, MYLK
dendritic spine 1 GRIN2A
cytoplasmic vesicle 1 C5AR1
nucleolus 3 GTPBP4, NUDT16, PLCZ1
apical part of cell 1 C5AR1
cell-cell junction 1 CD2
postsynaptic membrane 2 GRIN2A, P2RX1
presynaptic active zone membrane 1 P2RX1
Cell projection, lamellipodium 1 MYLK
Cytoplasm, perinuclear region 1 PLCZ1
Membrane raft 1 P2RX1
Peroxisome 1 XDH
basement membrane 1 ENTPD2
sarcoplasmic reticulum 1 XDH
Cell projection, dendritic spine 1 GRIN2A
PML body 1 SP3
Postsynaptic cell membrane 1 GRIN2A
neuron projection 1 GRIN2A
chromatin 2 SP1, SP3
Nucleus, nucleolus 2 GTPBP4, NUDT16
Basolateral cell membrane 1 GCK
Cytoplasmic vesicle membrane 1 GRIN2A
Nucleus, nucleoplasm 1 NUDT16
specific granule membrane 1 P2RX1
euchromatin 1 SP1
stress fiber 1 MYLK
synaptic membrane 1 GRIN2A
secretory granule membrane 2 C5AR1, P2RX1
transcription repressor complex 2 SP1, SP3
postsynaptic density membrane 1 GRIN2A
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
protein-DNA complex 2 SP1, SP3
NMDA selective glutamate receptor complex 1 GRIN2A
sperm head 1 PLCZ1
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Henryk Straube, Jannis Straube, Jannis Rinne, Lisa Fischer, Markus Niehaus, Claus-Peter Witte, Marco Herde. An inosine triphosphate pyrophosphatase safeguards plant nucleic acids from aberrant purine nucleotides. The New phytologist. 2023 03; 237(5):1759-1775. doi: 10.1111/nph.18656. [PMID: 36464781]
  • Shu-Yan Liu, Dai Yuan, Rui-Jie Sun, Jing-Jing Zhu, Ning-Ning Shan. Significant reductions in apoptosis-related proteins (HSPA6, HSPA8, ITGB3, YWHAH, and PRDX6) are involved in immune thrombocytopenia. Journal of thrombosis and thrombolysis. 2021 May; 51(4):905-914. doi: 10.1007/s11239-020-02310-5. [PMID: 33047245]
  • Jun-Xiu Liu, Huan-Xin Zhang, De-Peng Li, Wei-Wei Xing, Hu-Jun Li, Wei Chen, Hai Cheng, Jiang Cao, Zhen-Yu Li, Zhi-Ling Yan, Kai-Lin Xu. [Curative Efficacy of Rituximab for ITP Patients with Different Sensitivity to Hormone]. Zhongguo shi yan xue ye xue za zhi. 2019 Oct; 27(5):1602-1606. doi: 10.19746/j.cnki.issn.1009-2137.2019.05.037. [PMID: 31607319]
  • You-Ping Liao, Yu-Xia Liu, Qing-Zhao Li, Guo-Yu Hu. [Effect of Decitabine on Megakaryocyte Culture of Steroid-resistant ITP Patients]. Zhongguo shi yan xue ye xue za zhi. 2015 Aug; 23(4):1092-6. doi: 10.7534/j.issn.1009-2137.2015.04.036. [PMID: 26314452]
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