D-Carnitine (BioDeep_00000016570)

Main id: BioDeep_00000000070

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


D-Carnitine hydrochloride salt

化学式: C7H15NO3 (161.1052)
中文名称: 右旋肉碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C[N+](C)(C)CC(CC(=O)[O-])O
InChI: InChI=1/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m0/s1

描述信息

The (S)-enantiomer of carnitine.
Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

6 个代谢物同义名

(-)-L-Carnitine; (S)-Carnitine; D-Carnitine; D-Carnitine hydrochloride salt; L-carnitine; (S)-Carnitine



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALB, CLU, DAO, HPGDS, NQO1, PKM, SLC22A5
Peripheral membrane protein 4 CLU, CRAT, DAO, HSD17B6
Mitochondrion membrane 2 CLU, SLC22A4
Nucleus 5 ALB, CLU, NQO1, PKM, ZNF79
cytosol 10 ALB, CLU, CRAT, DAO, GPT, HPGDS, NQO1, PKM, SLC22A16, SLC22A5
dendrite 1 NQO1
mitochondrial membrane 2 CLU, SLC22A4
centrosome 1 ALB
nucleoplasm 1 HPGDS
Cell membrane 5 DAO, IL6R, SLC22A16, SLC22A5, TNF
Cytoplasmic side 1 CLU
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 4 ABCC3, SLC22A16, SLC22A4, SLC22A5
Synapse 2 CLU, NQO1
cell surface 2 CLU, TNF
Golgi apparatus 2 ALB, CLU
Golgi membrane 1 INS
lysosomal membrane 1 GAA
mitochondrial inner membrane 2 CLU, CRAT
neuronal cell body 2 NQO1, TNF
Cytoplasm, cytosol 3 CLU, DAO, NQO1
Lysosome 2 GAA, IL4I1
acrosomal vesicle 1 IL4I1
plasma membrane 8 ABCC3, DAO, GAA, IL6R, SLC22A16, SLC22A4, SLC22A5, TNF
presynaptic active zone 1 DAO
Membrane 7 ABCC3, GAA, IL6R, NQO1, SLC22A16, SLC22A4, SLC22A5
apical plasma membrane 3 IL6R, SLC22A4, SLC22A5
basolateral plasma membrane 1 ABCC3
extracellular exosome 7 ALB, CLU, DAO, GAA, GPT, PKM, SLC22A5
Lysosome membrane 1 GAA
Lumenal side 1 HSD17B6
endoplasmic reticulum 5 ALB, CLU, CRAT, HSD17B6, SLC22A5
extracellular space 6 ALB, CLU, DAO, IL6R, INS, TNF
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 CLU
bicellular tight junction 1 DAO
mitochondrion 4 CLU, CRAT, PKM, SLC22A4
protein-containing complex 2 ALB, CLU
intracellular membrane-bounded organelle 4 CLU, GAA, HPGDS, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 1 IL6R
Secreted 6 ALB, CLU, DAO, GAA, IL4I1, INS
extracellular region 9 ALB, CLU, DAO, GAA, IL4I1, IL6R, INS, PKM, TNF
[Isoform 2]: Secreted 1 IL6R
Extracellular side 1 DAO
anchoring junction 1 ALB
external side of plasma membrane 2 IL6R, TNF
Extracellular vesicle 1 PKM
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 PKM
Apical cell membrane 2 SLC22A4, SLC22A5
Cytoplasm, perinuclear region 1 CLU
Mitochondrion inner membrane 1 CRAT
Matrix side 1 CRAT
Membrane raft 1 TNF
Peroxisome 2 CRAT, DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 2 CRAT, DAO
collagen-containing extracellular matrix 2 CLU, PKM
receptor complex 1 IL6R
ciliary basal body 1 ALB
cilium 1 PKM
cell projection 1 DAO
phagocytic cup 1 TNF
centriole 1 ALB
Secreted, extracellular space 1 DAO
[Isoform 1]: Mitochondrion 1 CRAT
brush border membrane 1 SLC22A5
Cytoplasmic vesicle, secretory vesicle, acrosome 1 IL4I1
spindle pole 1 ALB
blood microparticle 2 ALB, CLU
sperm midpiece 1 IL4I1
Basolateral cell membrane 1 ABCC3
endosome lumen 1 INS
tertiary granule membrane 1 GAA
basal plasma membrane 3 ABCC3, SLC22A4, SLC22A5
[Isoform 4]: Cytoplasm 1 CLU
Microsome 1 CLU
ficolin-1-rich granule lumen 1 PKM
secretory granule lumen 2 INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 2 ALB, CLU
specific granule lumen 1 DAO
transport vesicle 1 INS
azurophil granule membrane 1 GAA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 IL4I1
Basal cell membrane 3 ABCC3, SLC22A4, SLC22A5
ficolin-1-rich granule membrane 1 GAA
apical dendrite 1 CLU
[Isoform 1]: Cell membrane 1 IL6R
Rough endoplasmic reticulum 1 PKM
[Isoform 3]: Endoplasmic reticulum 1 SLC22A5
spherical high-density lipoprotein particle 1 CLU
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 CLU
interleukin-6 receptor complex 1 IL6R
neurofibrillary tangle 1 CLU
Cytoplasmic vesicle, secretory vesicle, chromaffin granule 1 CLU
chromaffin granule 1 CLU
[Soluble interleukin-6 receptor subunit alpha]: Secreted 1 IL6R
ciliary neurotrophic factor receptor complex 1 IL6R
autolysosome lumen 1 GAA
[Isoform 6]: Cytoplasm 1 CLU
perinuclear endoplasmic reticulum lumen 1 CLU
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[Isoform 2]: Peroxisome 1 CRAT
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Ming Guo, Wei-Jun Lü, Ming-Hui Li, Wei Wang. Study on the binding interaction between carnitine optical isomer and bovine serum albumin. European journal of medicinal chemistry. 2008 Oct; 43(10):2140-8. doi: 10.1016/j.ejmech.2007.11.006. [PMID: 18166247]
  • Atsushi Enomoto, Michael F Wempe, Hiroki Tsuchida, Ho Jung Shin, Seok Ho Cha, Naohiko Anzai, Akiteru Goto, Atsuhiko Sakamoto, Toshimitsu Niwa, Yoshikatsu Kanai, M W Anders, Hitoshi Endou. Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. The Journal of biological chemistry. 2002 Sep; 277(39):36262-71. doi: 10.1074/jbc.m203883200. [PMID: 12089149]
  • H Yabuuchi, I Tamai, J Nezu, K Sakamoto, A Oku, M Shimane, Y Sai, A Tsuji. Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations. The Journal of pharmacology and experimental therapeutics. 1999 May; 289(2):768-73. doi: . [PMID: 10215651]