Peucedanin (BioDeep_00000007270)

 

Secondary id: BioDeep_00000410502

human metabolite PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylic acid delta-lactone

化学式: C15H14O4 (258.0892044)
中文名称: Peucedanin
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 36.84%

分子结构信息

SMILES: CC(C)C1=C(C2=C(O1)C=C3C(=C2)C=CC(=O)O3)OC
InChI: InChI=1S/C15H14O4/c1-8(2)14-15(17-3)10-6-9-4-5-13(16)18-11(9)7-12(10)19-14/h4-8H,1-3H3

描述信息

Peucedanin, also known as 2-isopropyl-3-methoxy-7h-furo[3,2-g]chromen-7-one or 4-methoxy-5-isopropylfuro(2,3:6,7)coumarin, is a member of the class of compounds known as psoralens. Psoralens are organic compounds containing a psoralen moiety, which consists of a furan fused to a chromenone to for 7H-furo[3,2-g]chromen-7-one. Peucedanin is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Peucedanin can be found in carrot, chervil, and wild carrot, which makes peucedanin a potential biomarker for the consumption of these food products.
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins

同义名列表

12 个代谢物同义名

6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylic acid delta-lactone; 6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylic acid δ-lactone; 6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylate delta-lactone; 6-Hydroxy-2-isopropyl-3-methoxy-5-benzofuranacrylate δ-lactone; 3-Methoxy-2-(1-methylethyl)-7H-furo(3,2-g)(1)benzopyran-7-one; 3-methoxy-2-(propan-2-yl)-7H-furo[3,2-g]chromen-7-one; 2-Isopropyl-3-methoxy-7H-furo[3,2-g]chromen-7-one; 4-Methoxy-5-isopropylfuro(2,3:6,7)coumarin; Oreoselone methyl ether; Peucedanin; Peucedanin; Peucedanin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Magdalena Bartnik. Efficient Separation of the Methoxyfuranocoumarins Peucedanin, 8-Methoxypeucedanin, and Bergapten by Centrifugal Partition Chromatography (CPC). Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041923. [PMID: 36838916]
  • Stepan A Kremis, Dmitry S Baev, Alla V Lipeeva, Elvira E Shults, Tatiana G Tolstikova, Olga I Sinitsyna, Alexey V Kochetov, Tatiana S Frolova. Genotoxic activity of 1,2,3-triazolyl modified furocoumarins and 2,3-dihydrofurocoumarins. Journal of biochemical and molecular toxicology. 2019 Nov; 33(11):e22396. doi: 10.1002/jbt.22396. [PMID: 31557364]
  • Alla V Lipeeva, Mikhail V Khvostov, Dmitry S Baev, Makhmut M Shakirov, Tatijana G Tolstikova, Elvira E Shults. Synthesis, in vivo Anticoagulant Evaluation and Molecular Docking Studies of Bicoumarins Obtained from Furocoumarin Peucedanin. Medicinal chemistry (Shariqah (United Arab Emirates)). 2016; 12(7):674-683. doi: 10.2174/1573406412666160129105115. [PMID: 26825067]
  • Ioanna Chinou, Jaroslaw Widelski, Nikolas Fokialakis, Prokopios Magiatis, Kazimierz Glowniak. Coumarins from Peucedanum luxurians. Fitoterapia. 2007 Sep; 78(6):448-9. doi: 10.1016/j.fitote.2007.04.004. [PMID: 17582700]
  • M Colombain, V Goll, F Muyard, C Girard, F Bévalot, L Richert. A bioassay using the human hepatoblastoma cell line HepG2 for detecting phototoxicity of furocoumarins. Planta medica. 2001 Oct; 67(7):644-6. doi: 10.1055/s-2001-17364. [PMID: 11582543]
  • A C Buck. Disorders of micturition in bacterial prostatitis. Proceedings of the Royal Society of Medicine. 1975 Aug; 68(8):508-11. doi: NULL. [PMID: 681]