Baccatin III (BioDeep_00000003704)

Main id: BioDeep_00000230460

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


Baccatin III

化学式: C31H38O11 (586.2414)
中文名称: 巴卡亭III, 巴卡丁 III
谱图信息: 最多检出来源 Homo sapiens(plant) 9.8%

分子结构信息

SMILES: CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)c2ccccc2)C2(O)CC(O)C(C)=C1C2(C)C
InChI: InChI=1S/C31H38O11/c1-15-19(34)13-31(38)26(41-27(37)18-10-8-7-9-11-18)24-29(6,20(35)12-21-30(24,14-39-21)42-17(3)33)25(36)23(40-16(2)32)22(15)28(31,4)5/h7-11,19-21,23-24,26,34-35,38H,12-14H2,1-6H3/t19-,20-,21+,23+,24-,26-,29+,30-,31+/m0/s1

描述信息

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.041
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.042
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.019
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.027
Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1].
Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1].

同义名列表

3 个代谢物同义名

Baccatin III; BCP09552; Baccatin III



数据库引用编号

39 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

  • taxol biosynthesis: acetyl-CoA + taxa-4(20),11-dien-5α-ol ⟶ coenzyme A + taxa-4(20),11-dien-5-α-yl acetate

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

  • taxol biosynthesis: O2 + a reduced [NADPH-hemoprotein reductase] + taxa-4(20),11-dien-5α-ol ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + taxa-4(20),11-dien-5α,13α-diol

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

134 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 ABCB1, ANXA5, BCL2, CASP10, CASP9, CYP3A4, GGPS1, HPGDS, IL13, PHB2, PRPF19, PTK2, STAT6, TUBB4B
Peripheral membrane protein 3 ANXA5, CYP1B1, PTK2
Endoplasmic reticulum membrane 4 BCL2, CYP1B1, CYP3A4, TBXAS1
Nucleus 8 BCL2, CASP9, DDX53, PHB2, PRPF19, PTK2, STAT6, TUBB4B
cytosol 12 ANXA5, BCL2, CASP10, CASP9, CD28, DDX53, GGPS1, HPGDS, PTK2, STAT6, TBXAS1, TUBB4B
centrosome 1 PTK2
nucleoplasm 5 DDX53, GGPS1, HPGDS, PRPF19, STAT6
RNA polymerase II transcription regulator complex 1 STAT6
Cell membrane 4 ABCB1, CD28, PHB2, PTK2
Cytoplasmic side 1 PTK2
Multi-pass membrane protein 3 ABCB1, CACNA1I, TBXAS1
cell cortex 1 PTK2
cell surface 3 ABCB1, CD28, PHB2
glutamatergic synapse 1 PHB2
mitochondrial inner membrane 1 PHB2
sarcolemma 1 ANXA5
plasma membrane 5 ABCB1, CACNA1I, CD28, PHB2, PTK2
presynaptic active zone 1 PHB2
Membrane 9 ABCB1, ANXA5, BCL2, CACNA1I, CYP1B1, CYP3A4, PHB2, PRPF19, TBXAS1
apical plasma membrane 1 ABCB1
axon 1 PHB2
extracellular exosome 3 ABCB1, ANXA5, TUBB4B
endoplasmic reticulum 2 BCL2, TBXAS1
extracellular space 2 IFNA1, IL13
perinuclear region of cytoplasm 2 GGPS1, PTK2
mitochondrion 4 BCL2, CASP9, CYP1B1, PHB2
protein-containing complex 3 BCL2, CASP9, PHB2
intracellular membrane-bounded organelle 5 CYP1B1, CYP3A4, DDX53, HPGDS, PTK2
Microsome membrane 2 CYP1B1, CYP3A4
postsynaptic density 1 PHB2
Secreted 2 IFNA1, IL13
extracellular region 3 ANXA5, IL13, TUBB4B
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, PHB2
anchoring junction 1 PTK2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 PTK2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 ANXA5, CD28, IL13
Extracellular vesicle 1 TUBB4B
dendritic spine 1 PTK2
Z disc 1 GGPS1
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 DDX53
Apical cell membrane 1 ABCB1
Cytoplasm, perinuclear region 2 GGPS1, PTK2
Mitochondrion inner membrane 1 PHB2
pore complex 1 BCL2
Cell junction, focal adhesion 1 PTK2
Cytoplasm, cytoskeleton 2 PTK2, TUBB4B
Cytoplasm, cytoskeleton, spindle 1 PRPF19
focal adhesion 2 ANXA5, PTK2
microtubule 1 TUBB4B
spindle 1 PRPF19
GABA-ergic synapse 1 PHB2
collagen-containing extracellular matrix 1 ANXA5
nuclear speck 1 PRPF19
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 PTK2
chromatin 1 STAT6
cell projection 1 PTK2
cell periphery 1 PHB2
mitotic spindle 1 TUBB4B
cytoskeleton 2 PTK2, TUBB4B
Cytoplasm, cytoskeleton, cilium basal body 1 PTK2
Cytoplasm, cell cortex 1 PTK2
spliceosomal complex 1 PRPF19
site of double-strand break 1 PRPF19
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
Lipid droplet 1 PRPF19
axonemal microtubule 1 TUBB4B
Nucleus, nucleoplasm 1 PRPF19
myelin sheath 1 BCL2
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
stress fiber 1 PTK2
nuclear matrix 1 PHB2
voltage-gated calcium channel complex 1 CACNA1I
azurophil granule lumen 1 TUBB4B
immunological synapse 1 CD28
apoptosome 1 CASP9
vesicle membrane 1 ANXA5
U2-type catalytic step 1 spliceosome 1 PRPF19
external side of apical plasma membrane 1 ABCB1
CD95 death-inducing signaling complex 1 CASP10
ripoptosome 1 CASP10
catalytic step 2 spliceosome 1 PRPF19
Prp19 complex 1 PRPF19
U2-type catalytic step 2 spliceosome 1 PRPF19
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[Isoform 3]: Cell surface 1 CD28
protein complex involved in cell adhesion 1 CD28
mitochondrial prohibitin complex 1 PHB2
[Isoform 2]: Mitochondrion inner membrane 1 PHB2
caspase complex 1 CASP9
[Isoform 1]: Mitochondrion inner membrane 1 PHB2


文献列表

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