N-Nitrosodipropylamine (BioDeep_00000002956)
Secondary id: BioDeep_00001868096
human metabolite blood metabolite
代谢物信息卡片
化学式: C6H14N2O (130.1106)
中文名称: 二丙基亚硝胺
谱图信息:
最多检出来源 Homo sapiens(plant) 17.89%
分子结构信息
SMILES: CCCN(CCC)N=O
InChI: InChI=1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
描述信息
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3456
D009676 - Noxae > D002273 - Carcinogens
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:82358
- KEGG: C19279
- PubChem: 12130
- HMDB: HMDB0255205
- Metlin: METLIN72997
- ChEMBL: CHEMBL166242
- CAS: 621-64-7
- MoNA: EQ345603
- MoNA: EQ345606
- MoNA: EQ345605
- MoNA: EQ345601
- MoNA: EQ345602
- MoNA: EQ345604
- PMhub: MS000007344
- PubChem: 124489951
- KNApSAcK: 82358
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chao Zhao, Qiang Lu, Yun Gu, Enchun Pan, Zhongming Sun, Hu Zhang, Jingjing Zhou, Ying Du, Ying Zhang, Yuanmei Feng, Ran Liu, Yuepu Pu, Lihong Yin. Distribution of N-nitrosamines in drinking water and human urinary excretions in high incidence area of esophageal cancer in Huai'an, China.
Chemosphere.
2019 Nov; 235(?):288-296. doi:
10.1016/j.chemosphere.2019.06.124. [PMID: 31260869] - Youngmin Hong, Kyung Hwan Kim, Byoung-In Sang, Hyunook Kim. Simple quantification method for N-nitrosamines in atmospheric particulates based on facile pretreatment and GC-MS/MS.
Environmental pollution (Barking, Essex : 1987).
2017 Jul; 226(?):324-334. doi:
10.1016/j.envpol.2017.04.017. [PMID: 28412030] - Xiao-Lin Liu, Wei-Wei Zheng, Xiao Wei, Han-Yi Chen, Xia Wang, Hong-Mei Zhang, Song-Hui Jiang, Geng-Sheng He, Wei-Dong Qu. [Investigation on the levels of carbon-, nitrogen-, iodine-containing disinfection by-products in a water plant in Jiangsu province, China].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
2012 Feb; 46(2):133-8. doi:
. [PMID: 22490195] - Dominic Sophia, Paramasivam Ragavendran, Chinthamony Arul Raj, Velliyur Kanniappan Gopalakrishnan. Protective effect of Emilia sonchifolia (L.) against high protein diet induced oxidative stress in pancreas of Wistar rats.
Journal of pharmacy & bioallied sciences.
2012 Jan; 4(1):60-5. doi:
10.4103/0975-7406.92735. [PMID: 22368400] - Megan H Plumlee, Montserrat López-Mesas, Andy Heidlberger, Kenneth P Ishida, Martin Reinhard. N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS.
Water research.
2008 Jan; 42(1-2):347-55. doi:
10.1016/j.watres.2007.07.022. [PMID: 17697696] - Kun Lin, Wenying Shen, Zhongying Shen, Yongning Wu, Shihhsin Lu. Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
International journal of cancer.
2002 Nov; 102(3):207-11. doi:
10.1002/ijc.10698. [PMID: 12397637] - S Itoh, M Miura, T Itoh, Y Miyauchi, M Suga, Y Takahashi, Y Kasahara, E Yamamura, H Hirono, H Shimada. N-Nitrosodi-n-propylamine induces organ specific mutagenesis with specific expression times in lacZ transgenic mice.
Mutation research.
1999 Aug; 444(2):309-19. doi:
10.1016/s1383-5718(99)00062-5. [PMID: 10521671] - F O Uhegbu, E N Maduagwu. Occurrence of nitrosatable amines in some Nigerian medicinal plants.
Bulletin of environmental contamination and toxicology.
1995 Nov; 55(5):643-9. doi:
10.1007/bf00203748. [PMID: 8563195] - K E Appel, C S Rühl, A G Hildebrandt. Metabolic inactivation of N-nitrosamines by cytochrome P-450 in vitro and in vivo.
IARC scientific publications.
1984; ?(57):443-51. doi:
. [PMID: 6533036] - E Suzuki, M Okada. Metabolic fate of N, N-dipropylnitrosamine and N, N-diamylnitrosamine in the rat, in relation to their lack of carcinogenic effect on the urinary bladder.
Gan.
1981 Aug; 72(4):552-61. doi:
. [PMID: 7308667] - K H Leung, M C Archer. Urinary metabolites of N-nitrosodipropylamine, N-nitroso-2-hydroxypropylpropylamine and N-nitroso-2-oxopropylpropylamine in the rat.
Carcinogenesis.
1981; 2(9):859-62. doi:
10.1093/carcin/2.9.859. [PMID: 7296770] - M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study.
Cancer treatment reports.
1979 Sep; 63(9-10):1663-7. doi:
. [PMID: 91435]
