Gene Association: NPIPA1
UniProt Search:
NPIPA1 (PROTEIN_CODING)
Function Description: nuclear pore complex interacting protein family member A1
found 18 associated metabolites with current gene based on the text mining result from the pubmed database.
N-NITROSODIPHENYLAMINE
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3355 D009676 - Noxae > D002273 - Carcinogens
Cysteic acid
Cysteic acid is a crystalline amino acid formed in the oxidation of cysteine; it is a precursor of taurine. A crystalline amino acid formed in the oxidation of cysteine; it is a precursor of taurine. [HMDB]
N-Nitrosodimethylamine
N-Nitrosodimethylamine is found in pepper (Capsicum annuum). N-Nitrosodimethylamine is a food contaminant especially in cured meat products. N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is a semi-volatile organic chemical that is highly toxic and is a suspected human carcinogen. The US Environmental Protection Agency has determined that the maximum admissible concentration of NDMA in drinking water is 7 ng L 1. The EPA has not yet set a regulatory maximum contaminant level (MCL) for drinking water. At high doses, it is a "potent hepatotoxin that can cause fibrosis of the liver" in rats. The induction of liver tumors in rats after chronic exposure to low doses is well-documented. Its toxic effects on humans are inferred from animal experiments but not well-established experimentally. NDMA is an industrial by-product or waste product of several industrial processes. It first came to attention as a groundwater contaminant in California in 1998 and 1999 at several sites that produced rocket fuel. Manufacturing of unsymmetrical dimethylhydrazine (UDMH), which is a component of rocket fuel that requires NDMA for its synthesis, proved to be the culprit in these cases. Of more general concern, water treatment via chlorination or chloramination of organic nitrogen-containing wastewater can lead to the production of NDMA at potentially harmful levels. Further, NDMA can form or be leached during treatment of water by anion exchange resins. Finally, NDMA is found at low levels in numerous items of human consumption including cured meat, fish, beer, and tobacco smoke, it is, however, unlikely to bioaccumulate CONFIDENCE standard compound; EAWAG_UCHEM_ID 3447 Food contaminant especies in cured meat products
N-Nitrosodipropylamine
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3456 D009676 - Noxae > D002273 - Carcinogens
N-NITROSOMORPHOLINE
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3454 CONFIDENCE standard compound; INTERNAL_ID 4127 CONFIDENCE standard compound; INTERNAL_ID 8689 D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
N-Nitroso-pyrrolidine
N-Nitroso-pyrrolidine belongs to the class of organic compounds known as pyrrolidines. Pyrrolidines are compounds containing a pyrrolidine ring, which is a five-membered saturated aliphatic heterocycle with one nitrogen atom and four carbon atoms. N-Nitroso-pyrrolidine has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers. This could make N-nitroso-pyrrolidine a potential biomarker for the consumption of these foods. CONFIDENCE standard compound; EAWAG_UCHEM_ID 3450 Found in fried bacon
N-Nitrosopiperidine
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3453 D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
Potassium nitrate (KNO3)
Preservative for cod roe, cured red meat and poultry products. Potassium nitrate (KNO3) is found in fishes, animal foods, and common sage. D053834 - Explosive Agents Same as: D02051
N-NITROSOMORPHOLINE
D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
1-Nitrosopiperidine
A nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
