resmethrin (BioDeep_00000001765)

   

human metabolite blood metabolite


代谢物信息卡片


5-Benzyl-3-furylmethyl (1Rs,3Rs;1Rs,3Sr)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid

  化学式: C22H26O3 (338.1882)
中文名称: 苄蚨菊酯
  谱图信息: 最多检出来源 Homo sapiens(blood) 2.73%

分子结构信息

SMILES: CC(=CC1C(C1(C)C)C(=O)OCC2=COC(=C2)CC3=CC=CC=C3)C
InChI: InChI=1S/C22H26O3/c1-15(2)10-19-20(22(19,3)4)21(23)25-14-17-12-18(24-13-17)11-16-8-6-5-7-9-16/h5-10,12-13,19-20H,11,14H2,1-4H3


描述信息

DATA_PROCESSING MERGING RMBmix ver. 0.2.7; CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10738; ORIGINAL_PRECURSOR_SCAN_NO 10736
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10738; ORIGINAL_PRECURSOR_SCAN_NO 10736
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10701; ORIGINAL_PRECURSOR_SCAN_NO 10696
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10728; ORIGINAL_PRECURSOR_SCAN_NO 10725
INTERNAL_ID 158; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10689; ORIGINAL_PRECURSOR_SCAN_NO 10685
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10714; ORIGINAL_PRECURSOR_SCAN_NO 10710
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10668; ORIGINAL_PRECURSOR_SCAN_NO 10665
CONFIDENCE standard compound; INTERNAL_ID 158; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10689; ORIGINAL_PRECURSOR_SCAN_NO 10685
D010575 - Pesticides > D007306 - Insecticides > D011722 - Pyrethrins
D016573 - Agrochemicals

同义名列表

119 个代谢物同义名

5-Benzyl-3-furylmethyl (1Rs,3Rs;1Rs,3Sr)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylic acid; 5-Benzyl-3-furylmethyl (1Rs,3Rs;1Rs,3Sr)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; (5-(Phenylmethyl)-3-furanyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid; (5-(Phenylmethyl)-3-furanyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate; (5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; (5-Benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methylpropenyl)cyclopropemecarboxylate; 5-Benzyl-3-furylmethyl (+-)-cis,trans-chrysanthemic acid; 5-Benzyl-3-furylmethyl (+-)-cis,trans-chrysanthemate; resmethrin; Scourge; Durekyl; for-syn; Ectokyl; Resmethrin; Resmethrin; (1R trans)-2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid [5-(phenylmethyl)-3-furanyl] methyl ester; (5-(Phenylmethyl)-3-furanyl) methyl 2,2-dimethyl-3-(2-methyl-1-propenyl) cyclopropanecarboxylate); (5-(Phenylmethyl)-3-furanyl)methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate (9CI); (5-(Phenylmethyl)-3-furanyl)methyl 2,2-dimethyl-3-furylmethyl 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate; (5-(Phenylmethyl)-3-furanyl)methyl-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate; (5-Benzyl-3-furyl) methyl-2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarboxylate; (5-Benzyl-3-furyl)methyl (1RS)-cis-trans-chrysanthemate; (5-benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate; (5-benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; (5-Benzyl-3-furyl)methyl 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate; (5-Benzyl-3-furyl)methyl chrysanthemate; (5-BENZYL-3-FURYL)METHYL-DL-CIS, TRANS-CHRYSANTHEMATE; (5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate; (5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate; (5-benzylfuran-3-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; (5-Phenylmethyl-3-furan)methyl-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropane carboxylate; (5(Phenylmethyl)3furanyl)methyl 2,2dimethyl3(2methyl1propenyl)cyclopropanecarboxylate; (5(Phenylmethyl)3furanyl)methyl 2,2dimethyl3(2methyl1propenyl)cyclopropanecarboxylate (9CI); (5Benzyl3furyl) methyl2,2dimethyl3(2methylpropenyl)cyclopropanecarboxylate; (5Benzyl3furyl)methyl 2,2dimethyl3(2methylpropenyl)cyclopropanecarboxylate; (5Phenylmethyl3furan)methyl2,2dimethyl3(2methyl1propenyl)cyclopropane carboxylate; [5-(phenylmethyl)furan-3-yl]methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cycloprop; 1S, cis-Resmethrin; 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate; 3-FURANMETHANOL, 5-BENZYL-, 2,2-DIMETHYL-3-(2-METHYLPROPENYL)CYCLOPROPANECARBOXYLATE; 5-(PHENYLMETHYL)-3-FURANYL)METHYL; 5-Benzyl-3-furylmethyl (+-)-cis-trans-chrysanthemate; 5-BENZYL-3-FURYLMETHYL (+/-)-CIS-TRANS-CHRYSANTHEMATE; 5-Benzyl-3-furylmethyl (1RS, 3RS; 1RS, 3SR)-2,2-dimethyl-3-(2-methylprop=1-enyl)cyclopropanecarboxylate; 5-Benzyl-3-furylmethyl (1RS)-cis-trans-2,2-dimethyl-3-(2-methylprop-1-enyl) cyclopropanecarboxylate; 5-Benzyl-3-furylmethyl (1RS)-cis-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; 5-Benzyl-3-furylmethyl (1RS)-cis,trans-chrysanthemate; 5-Benzyl-3-furylmethyl(.+/-.)-cis,trans-chrysanthemate; 5-Benzyl-3-furylmethyl(+-)-cis,trans-chrysanthemate; 5-Benzyl-3-furylmethyl(+)-trans-chrysanthemate; 5-Benzyl-3-furylmethyl(+/-)-cis,trans-chrysanthemate; 5-Benzylfurfuryl chrysanthemate; 5Benzyl3furylmethyl (+)cistranschrysanthemate; 5Benzyl3furylmethyl (1RS,3RS; 5Benzyl3furylmethyl(+)cis,transchrysanthemate; 5Benzylfurfuryl chrysanthemate; AI3-27474; ARI-B; Benzofuroline; Benzofuroline; Isathrine; Benzyfuroline; BENZYLFUROLINE; Biobenzylfuroline; Bioresmethrin (d trans isomer); Chryson; Chrysron; Combat White Fly Insecticide; Crossfire; CYCLOPROPANECARBOXYLIC ACID, 2,2-DIMETHYL-3-(2-METHYL-1-PROPEN-1-YL)-, (5-(PHENYLMETHYL)-3-FURANYL)METHYL ESTER; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (5-(phenylmethyl)-3-furanyl)methyl ester; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (5-(phenylmethyl)-3-furanyl)methyl ester, (1R-trans)-; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (5-(phenylmethyl)-3-furanyl)methyl ester, cis,trans-(+/-)-; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, [5-(phenylmethyl)-3-furanyl]methyl ester; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, [5-(phenylmethyl)-3-furanyl]methyl ester, (1R-trans)-; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, (4-(2-benzyl)furyl) methyl ester; Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, (5-benzyl-3-furyl)methyl ester; Cyclopropanecarboxylic acid, 2,2dimethyl3(2methyl1propenyl), (5(phenylmethyl)3furanyl)methyl ester; Cyclopropanecarboxylic acid, 2,2dimethyl3(2methylpropenyl), (4(2benzyl)furyl) methyl ester; Cyclopropanecarboxylic acid, 2,2dimethyl3(2methylpropenyl), (5benzyl3furyl)methyl ester; D-Resmethrin; d-trans-Resmethrin; Dimethyl 3-(2-methyl-1-propenyl)cyclopropanecarboxylate; DL-CIS,TRANS-((5-BENZYL-3-FURYL)METHYL)CHRYSANTHEMUMATE; Durekyl (TN); Ectokyl (TN); Enforcer; Forsyn; HSCI1_000127; InChI=1/C22H26O3/c1-15(2)10-19-20(22(19,3)4)21(23)25-14-17-12-18(24-13-17)11-16-8-6-5-7-9-16/h5-10,12-13,19-20H,11,14H2,1-4H3; Isathrine; Penncapthrin; Premgard; Pyresthrin; Pyretherm; Raid flying insect killer; Resbuthrin; Resmethrin (ANSI); Resmethrin [ANSI]; RESMETHRIN [INCI]; Resmethrin [ISO]; RESMETHRIN [MI]; Resmethrin 10 microg/mL in Cyclohexane; RESMETHRIN TECHNICAL; Resmethrin, PESTANAL(R), analytical standard; Resmethrine; Resmethrine (ISO-French); Resmethrine [ISO-French]; Resmetrina; RESMETRINA (PORTUGUESE); Resmetrina [Portuguese]; Sun-Bugger; Sun-Bugger 4; Synthrin; Syntox; Tox21_202138; Tox21_300920; UNII-Z6PN6KTG4K; VEMKTZHHVJILDY-UHFFFAOYSA-; Z6PN6KTG4K



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 AR, CSTB, HPGDS, NR3C1, TSC22D3
Peripheral membrane protein 2 AP2S1, CYP27A1
Endosome membrane 1 CLCN5
Mitochondrion membrane 2 ABCG2, CYP27A1
Nucleus 8 AR, CHD7, CSTB, H2AX, KDR, NR3C1, SYCP3, TSC22D3
cytosol 8 AP2S1, AR, CLCN5, CSTB, HPGDS, NR3C1, TNNI3, TSC22D3
dendrite 1 OPRM1
mitochondrial membrane 1 ABCG2
centrosome 2 H2AX, NR3C1
nucleoplasm 7 ABCG2, AR, CHD7, H2AX, HPGDS, NR3C1, SCNN1G
Cell membrane 5 ABCG2, AP2S1, CLCN5, KDR, OPRM1
Cytoplasmic side 1 AP2S1
Cell projection, axon 1 OPRM1
Multi-pass membrane protein 4 ABCG2, CLCN5, OPRM1, SCNN1G
Golgi apparatus membrane 1 CLCN5
Synapse 2 NR3C1, OPRM1
cell junction 1 KDR
cell surface 1 TNR
glutamatergic synapse 1 TNR
Golgi apparatus 3 CLCN5, KDR, OPRM1
Golgi membrane 1 CLCN5
lysosomal membrane 1 CLCN5
mitochondrial inner membrane 1 CYP27A1
postsynapse 1 AP2S1
synaptic vesicle 1 CLCN5
Presynapse 1 AP2S1
endosome 2 KDR, OPRM1
plasma membrane 7 ABCG2, AP2S1, AR, CLCN5, KDR, OPRM1, SCNN1G
Membrane 5 ABCG2, AR, CLCN5, NR3C1, OPRM1
apical plasma membrane 2 ABCG2, SCNN1G
axon 1 OPRM1
extracellular exosome 4 CSTB, H2AX, SCNN1G, SHBG
endoplasmic reticulum 2 KDR, OPRM1
extracellular space 3 CSTB, TG, TNR
Schaffer collateral - CA1 synapse 1 TNR
mitochondrion 3 CYP27A1, NR3C1, PCK2
protein-containing complex 2 AR, NR3C1
intracellular membrane-bounded organelle 2 AP2S1, HPGDS
Secreted 2 SHBG, TG
extracellular region 5 CSTB, KDR, SHBG, TG, TNR
cytoplasmic side of plasma membrane 1 AP2S1
[Isoform 2]: Secreted 1 KDR
mitochondrial matrix 3 CYP27A1, NR3C1, PCK2
anchoring junction 1 KDR
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
external side of plasma membrane 2 KDR, SCNN1G
Secreted, extracellular space, extracellular matrix 1 TNR
perikaryon 1 OPRM1
nucleolus 2 CHD7, CSTB
Early endosome 2 CLCN5, KDR
apical part of cell 1 CLCN5
Apical cell membrane 2 ABCG2, SCNN1G
Mitochondrion inner membrane 1 CYP27A1
Membrane raft 3 ABCG2, KDR, TNR
Cytoplasm, cytoskeleton, spindle 1 NR3C1
spindle 1 NR3C1
collagen-containing extracellular matrix 2 CSTB, TNR
nuclear speck 3 AR, H2AX, NR3C1
sarcomere 1 TNNI3
receptor complex 1 KDR
neuron projection 1 OPRM1
chromatin 3 AR, CHD7, NR3C1
cell periphery 1 AP2S1
Chromosome 3 H2AX, NR3C1, SYCP3
brush border membrane 1 ABCG2
site of double-strand break 1 H2AX
sorting endosome 1 KDR
Chromosome, centromere 1 SYCP3
lateral element 1 SYCP3
sodium channel complex 1 SCNN1G
Nucleus, nucleoplasm 1 NR3C1
Cell projection, dendrite 1 OPRM1
replication fork 1 H2AX
[Isoform 1]: Cytoplasm 1 TSC22D3
ficolin-1-rich granule lumen 1 CSTB
secretory granule lumen 1 CSTB
male germ cell nucleus 1 H2AX
tertiary granule lumen 1 CSTB
endocytic vesicle membrane 1 AP2S1
XY body 1 H2AX
perineuronal net 1 TNR
clathrin-coated endocytic vesicle 1 AP2S1
condensed nuclear chromosome 1 H2AX
chromosome, centromeric region 1 SYCP3
clathrin-coated endocytic vesicle membrane 1 AP2S1
[Isoform 1]: Nucleus 1 CHD7
external side of apical plasma membrane 1 ABCG2
endolysosome membrane 1 AP2S1
synaptonemal complex 1 SYCP3
nucleosome 1 H2AX
membrane coat 1 AP2S1
Membrane, coated pit 1 AP2S1
site of DNA damage 1 H2AX
[Isoform Alpha]: Cytoplasm 1 NR3C1
AP-2 adaptor complex 1 AP2S1
cardiac myofibril 1 TNNI3
troponin complex 1 TNNI3
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
cardiac Troponin complex 1 TNNI3
tenascin complex 1 TNR
[Isoform 12]: Cytoplasm 1 OPRM1
[Isoform 3]: Nucleus, nucleolus 1 CHD7


文献列表

  • Yifan Wang, Mengru An, Kelly M Stevens, Nannan Liu. Insecticide Resistance in Alabama Populations of the Mosquito Aedes albopictus. Journal of medical entomology. 2022 09; 59(5):1678-1686. doi: 10.1093/jme/tjac085. [PMID: 35851609]
  • Kristin M Bircsak, Jason R Richardson, Lauren M Aleksunes. Inhibition of human MDR1 and BCRP transporter ATPase activity by organochlorine and pyrethroid insecticides. Journal of biochemical and molecular toxicology. 2013 Feb; 27(2):157-64. doi: 10.1002/jbt.21458. [PMID: 23169446]
  • Yoshie Hata, Stefanie Zimmermann, Melanie Quitschau, Marcel Kaiser, Matthias Hamburger, Michael Adams. Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids. Journal of agricultural and food chemistry. 2011 Sep; 59(17):9172-6. doi: 10.1021/jf201776z. [PMID: 21786822]
  • Ting Yang, Nannan Liu. Genome analysis of cytochrome P450s and their expression profiles in insecticide resistant mosquitoes, Culex quinquefasciatus. PloS one. 2011; 6(12):e29418. doi: 10.1371/journal.pone.0029418. [PMID: 22242119]
  • Matthew T Martin, Richard S Judson, David M Reif, Robert J Kavlock, David J Dix. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environmental health perspectives. 2009 Mar; 117(3):392-9. doi: 10.1289/ehp.0800074. [PMID: 19337514]
  • A O J Amoo, Rui-De Xue, W A Qualls, B P Quinn, U R Bernier. Residual efficacy of field-applied permethrin, d-phenothrin, and resmethrin on plant foliage against adult mosquitoes. Journal of the American Mosquito Control Association. 2008 Dec; 24(4):543-9. doi: 10.2987/08-5783.1. [PMID: 19181063]
  • R Joseph Woodrow, J Kenneth Grace, Robert J Oshiro. Comparison of localized injections of spinosad and selected insecticides for the control of Cryptotermes brevis (Isoptera: Kalotermitidae) in naturally infested structural mesocosms. Journal of economic entomology. 2006 Aug; 99(4):1354-62. doi: 10.1603/0022-0493-99.4.1354. [PMID: 16937692]
  • Gabriele Leng, Wolfgang Gries, Sami Selim. Biomarker of pyrethrum exposure. Toxicology letters. 2006 Apr; 162(2-3):195-201. doi: 10.1016/j.toxlet.2005.09.030. [PMID: 16257148]
  • Gabriele Leng, Wolfgang Gries. Simultaneous determination of pyrethroid and pyrethrin metabolites in human urine by gas chromatography-high resolution mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Jan; 814(2):285-94. doi: 10.1016/j.jchromb.2004.10.044. [PMID: 15639450]
  • Huqi Liu, Eddie W Cupp, Aiguang Guo, Nannan Liu. Insecticide resistance in Alabama and Florida mosquito strains of Aedes albopictus. Journal of medical entomology. 2004 Sep; 41(5):946-52. doi: 10.1603/0022-2585-41.5.946. [PMID: 15535626]
  • Huqi Liu, Eddie W Cupp, Kelly M Micher, Aiguang Guo, Nannan Liu. Insecticide resistance and cross-resistance in Alabama and Florida strains of Culex quinquefasciatus [correction]. Journal of medical entomology. 2004 May; 41(3):408-13. doi: 10.1603/0022-2585-41.3.408. [PMID: 15185942]
  • Bobby L Loper, Kim A Anderson. Determination of pyrethrin and pyrethroid pesticides in urine and water matrixes by liquid chromatography with diode array detection. Journal of AOAC International. 2003 Nov; 86(6):1236-40. doi: . [PMID: 14979708]
  • G D Lowe, C D Forbes, C R Prentice. Plasma-fibrinogen thromboembolism, and hit fractures. Lancet (London, England). 1977 Feb; 1(8008):426. doi: 10.1016/s0140-6736(77)92634-4. [PMID: 65536]