Stevioside (BioDeep_00000000005)

   

human metabolite PANOMIX_OTCML-2023 Endogenous Antitumor activity natural product


代谢物信息卡片


(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate

化学式: C38H60O18 (804.3779)
中文名称: 甜菊糖, 甜菊苷
谱图信息: 最多检出来源 Viridiplantae(plant) 71.55%

Reviewed

Last reviewed on 2024-08-26.

Cite this Page

Stevioside. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/stevioside (retrieved 2024-12-21) (BioDeep RN: BioDeep_00000000005). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C=C1CC23CCC4C(C)(C(=O)OC5OC(CO)C(O)C(O)C5O)CCCC4(C)C2CCC1(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O)C3
InChI: InChI=1S/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-29(49)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-30(27(47)24(44)19(14-41)53-33)54-31-28(48)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32+,33+,35-,36-,37-,38+/m1/s1

描述信息

Stevioside is a diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America. It has a role as a sweetening agent, an antioxidant, an antineoplastic agent, a hypoglycemic agent, an anti-inflammatory agent and a plant metabolite. It is a diterpene glycoside, an ent-kaurane diterpenoid, a beta-D-glucoside, a tetracyclic diterpenoid and a bridged compound. It is functionally related to a steviol and a rubusoside.
Stevioside is a natural product found in Asteraceae, Stevia rebaudiana, and Bos taurus with data available.
See also: Stevia rebaudiuna Leaf (part of).
Stevioside is a constituent of Stevia rebaudiana (stevia). Sweetening agent which is 300 times sweeter than sucrose. Stevia rebaudiana is extensively cultivated in Japan, and Stevioside is a permitted sweetener in that country Rebaudioside B, D, and E may also be present in minute quantities; however, it is suspected that rebaudioside B is a byproduct of the isolation technique. The two majority compounds stevioside and rebaudioside, primarily responsible for the sweet taste of stevia leaves, were first isolated by two French chemists in 1931
A diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America.
Constituent of Stevia rebaudiana (stevia). Sweetening agent which is 300 times sweeter than sucrose. Stevia rebaudiana is extensively cultivated in Japan, and Stevioside is a permitted sweetener in that country
D000074385 - Food Ingredients > D005503 - Food Additives
D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents
Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana, with anticancer activity[1].
Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana, with anticancer activity[1].

Stevioside. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=57817-89-7 (retrieved 2024-08-26) (CAS RN: 57817-89-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

46 个代谢物同义名

(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1R,4S,5R,9S,10R,13S)-13-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5-carboxylate; [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-dimethyl-methylene-[?]carboxylate; 1-O-{(5beta,8alpha,9beta,10alpha,13alpha)-13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxokaur-16-en-18-yl}-beta-D-glucopyranose; 1-O-{13alpha-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl}-beta-D-glucopyranose; 1-O-(13alpha-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; KAUR-16-EN-18-OIC ACID, 13-((2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)-, .BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-; (4.ALPHA.)-13-((2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID .BETA.-D-GLUCOPYRANOSYL ESTER; KAUR-16-EN-18-OIC ACID, 13-((2-O-beta-D-GLUCOPYRANOSYL-beta-D-GLUCOPYRANOSYL)OXY)-, beta-D-GLUCOPYRANOSYL ESTER, (4alpha)-; 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid, (4alpha)-beta-D-glucopyranosyl ester; (4alpha)-13-((2-O-beta-D-GLUCOPYRANOSYL-beta-D-GLUCOPYRANOSYL)OXY)KAUR-16-EN-18-OIC ACID beta-D-GLUCOPYRANOSYL ESTER; 13-[(2-O-.beta.-D-Glucopyranosyl-.alpha.-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid .beta.-D-glucopyranosyl ester; 13-((2-O-.beta.-D-Glucopyranosyl-.alpha.-D-glucopyranosyl)oxy)kaur-16-en-18-oic acid .beta.-D-glucopyranosyl ester; Kaur-16-en-18-oic acid, 13-((2-O-beta-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy)-, beta-D-glucopyranosyl ester; 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oic acid beta-D-glucopyranosyl ester; 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid beta-D-glucopyranosyl ester; Kaur-16-en-18-oic acid,13-[(2-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-,b-D-glucopyranosyl ester, (4a)-; (4alpha)-beta-D-Glucopyranosyl 13-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)kaur-16-en-18-oate; 13-[(2-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]kaur-16-en-18-Oate beta-D-glucopyranosyl ester; 13-[(2-O-Β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-Oic acid β-D-glucopyranosyl ester; 13-[(2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]kaur-16-en-18-Oic acid b-D-glucopyranosyl ester; 13-[(2-O-Β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]kaur-16-en-18-Oate β-D-glucopyranosyl ester; 13-[(2-O-b-D-Glucopyranosyl-b-D-glucopyranosyl)oxy]kaur-16-en-18-Oate b-D-glucopyranosyl ester; 4-17-00-03618 (Beilstein Handbook Reference); UEDUENGHJMELGK-HYDKPPNVSA-N; STEVIOSIDE (USP-RS); Diterpene glycoside; STEVIOSIDE [USP-RS]; STEVIOSIDE (MART.); STEVIOSIDE [MART.]; steviol glycoside; STEVIOSIDE [INCI]; UNII-0YON5MXJ9P; STEVIOSIDE [MI]; .ALPHA.-G-SWEET; (-)-STEVIOSIDE; 1,2-Stevioside; alpha-G-SWEET; STEVIBIOSIDE; 0YON5MXJ9P; STEVIAN 50; Stevioside; Eupatorin?; Steviosin; Rebaudin; Stevin?; Stevioside



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(1)

代谢反应

63 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(63)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

88 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AIMP2, BCL2, CAT, CDH1, HPGDS, NOS2, PIK3CA, PPARG, PTGS2, STAT3, TLR4
Peripheral membrane protein 2 GORASP1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS2
Nucleus 7 AIMP2, BCL2, CDH1, HMOX1, NOS2, PPARG, STAT3
cytosol 11 AIMP2, BCL2, CAT, CDH1, HMOX1, HPGDS, NOS2, PIK3CA, PPARG, SLC2A4, STAT3
trans-Golgi network 2 CDH1, SLC2A4
nucleoplasm 6 CDH1, HMOX1, HPGDS, NOS2, PPARG, STAT3
RNA polymerase II transcription regulator complex 2 PPARG, STAT3
Cell membrane 4 CDH1, SLC2A4, TLR4, TNF
Cytoplasmic side 2 GORASP1, HMOX1
lamellipodium 2 CDH1, PIK3CA
Multi-pass membrane protein 1 SLC2A4
Golgi apparatus membrane 1 GORASP1
cell junction 1 CDH1
cell surface 2 TLR4, TNF
glutamatergic synapse 1 CDH1
Golgi apparatus 3 CDH1, GORASP1, TAS1R3
Golgi membrane 2 GORASP1, INS
neuronal cell body 1 TNF
postsynapse 1 CDH1
sarcolemma 1 SLC2A4
Cytoplasm, cytosol 2 AIMP2, NOS2
Presynapse 1 SLC2A4
endosome 1 CDH1
plasma membrane 10 CDH1, GCG, NOS2, PIK3CA, SLC2A4, STAT3, TAS1R2, TAS1R3, TLR4, TNF
Membrane 9 AIMP2, BCL2, CAT, CDH1, HMOX1, SLC2A4, TAS1R2, TAS1R3, TLR4
caveola 1 PTGS2
extracellular exosome 3 CAT, CDH1, SLC2A4
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 5 GCG, HMOX1, IL6, INS, TNF
perinuclear region of cytoplasm 7 CDH1, HMOX1, NOS2, PIK3CA, PPARG, SLC2A4, TLR4
adherens junction 1 CDH1
intercalated disc 1 PIK3CA
mitochondrion 2 BCL2, CAT
protein-containing complex 3 BCL2, CAT, PTGS2
intracellular membrane-bounded organelle 3 CAT, HPGDS, PPARG
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 2 CDH1, TLR4
Secreted 3 GCG, IL6, INS
extracellular region 6 CAT, CDH1, GCG, IL6, INS, TNF
cytoplasmic side of plasma membrane 1 CDH1
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 1 CAT
transcription regulator complex 1 STAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, CDH1
external side of plasma membrane 3 SLC2A4, TLR4, TNF
multivesicular body 1 SLC2A4
actin cytoskeleton 1 CDH1
T-tubule 1 SLC2A4
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 TLR4
clathrin-coated pit 1 SLC2A4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 2 NOS2, SLC2A4
Membrane raft 2 SLC2A4, TNF
pore complex 1 BCL2
focal adhesion 1 CAT
cis-Golgi network 1 GORASP1
Cell junction, adherens junction 1 CDH1
flotillin complex 1 CDH1
Peroxisome 2 CAT, NOS2
sarcoplasmic reticulum 1 SLC2A4
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, NOS2
peroxisomal membrane 1 CAT
lateral plasma membrane 1 CDH1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 3 PPARG, TAS1R2, TLR4
neuron projection 1 PTGS2
chromatin 2 PPARG, STAT3
phagocytic cup 2 TLR4, TNF
Golgi apparatus, trans-Golgi network 1 CDH1
Endomembrane system 1 SLC2A4
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 SLC2A4
myelin sheath 1 BCL2
clathrin-coated vesicle 1 SLC2A4
trans-Golgi network transport vesicle 1 SLC2A4
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 GCG, IL6, INS, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
anaphase-promoting complex 1 CDH1
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Single-pass type IV membrane protein 1 HMOX1
vesicle membrane 1 SLC2A4
[Isoform 2]: Nucleus 1 CDH1
apical junction complex 1 CDH1
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
Cell junction, desmosome 1 CDH1
desmosome 1 CDH1
catenin complex 1 CDH1
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
insulin-responsive compartment 1 SLC2A4
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
sweet taste receptor complex 2 TAS1R2, TAS1R3


文献列表

  • Joanna Śniegowska, Anita Biesiada, Alan Gasiński. Influence of the Nitrogen Fertilization on the Yield, Biometric Characteristics and Chemical Composition of Stevia rebaudiana Bertoni Grown in Poland. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081865. [PMID: 38675686]
  • Shan Li, Shuangshuang Luo, Xingying Zhao, Song Gao, Xiaoyu Shan, Jian Lu, Jingwen Zhou. Efficient Conversion of Stevioside to Rebaudioside M in Saccharomyces cerevisiae by a Engineering Hydrolase System and Prolonging the Growth Cycle. Journal of agricultural and food chemistry. 2024 Apr; 72(14):8140-8148. doi: 10.1021/acs.jafc.4c01483. [PMID: 38563232]
  • Mei-Li Xu, Yuanxin Cheng, Mo Feng, Qingguo Lu, Yunhe Lian. Identifying Potential Sources of Phthalate Contamination in the Leaves of Stevia Rebaudiana (Bertoni) and the Development of Removal Technology. Molecules (Basel, Switzerland). 2024 Apr; 29(7):. doi: 10.3390/molecules29071627. [PMID: 38611906]
  • Xiuqiong Zhang, Tiantian Chen, Zaifang Li, Xinxin Wang, Han Bao, Chunxia Zhao, Xinjie Zhao, Xin Lu, Guowang Xu. Fine-Scale Characterization of Plant Diterpene Glycosides Using Energy-Resolved Untargeted LC-MS/MS Metabolomics Analysis. Journal of the American Society for Mass Spectrometry. 2024 Mar; 35(3):603-612. doi: 10.1021/jasms.3c00420. [PMID: 38391322]
  • Samuel Simoni, Alberto Vangelisti, Clarissa Clemente, Gabriele Usai, Marco Santin, Maria Ventimiglia, Flavia Mascagni, Lucia Natali, Luciana G Angelini, Andrea Cavallini, Silvia Tavarini, Tommaso Giordani. Transcriptomic Analyses Reveal Insights into the Shared Regulatory Network of Phenolic Compounds and Steviol Glycosides in Stevia rebaudiana. International journal of molecular sciences. 2024 Feb; 25(4):. doi: 10.3390/ijms25042136. [PMID: 38396813]
  • Jakub Michał Kurek, Joanna Mikołajczyk-Stecyna, Zbigniew Krejpcio. Steviol glycosides from Stevia rebaudiana Bertoni mitigate lipid metabolism abnormalities in diabetes by modulating selected gene expression - An in vivo study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Oct; 166(?):115424. doi: 10.1016/j.biopha.2023.115424. [PMID: 37677968]
  • Agata Ptak, Agnieszka Szewczyk, Magdalena Simlat, Alicja Błażejczak, Marzena Warchoł. Meta-Topolin-induced mass shoot multiplication and biosynthesis of valuable secondary metabolites in Stevia rebaudiana Bertoni bioreactor culture. Scientific reports. 2023 09; 13(1):15520. doi: 10.1038/s41598-023-42619-8. [PMID: 37726319]
  • Pritom Biswas, Ankita Kumari, Arpan Modi, Nitish Kumar. Improvement and Regulation of Steviol Glycoside Biosynthesis in Stevia rebaudiana Bertoni. Gene. 2023 Sep; ?(?):147809. doi: 10.1016/j.gene.2023.147809. [PMID: 37722610]
  • Yu Wang, Peiyu Xu, Wenxia Wang, Xiaochen Jia, Liping Zhu, Heng Yin. Oligosaccharides increased both leaf biomass and steviol glycosides content of Stevia rebaudiana. Plant physiology and biochemistry : PPB. 2023 Aug; 202(?):107937. doi: 10.1016/j.plaphy.2023.107937. [PMID: 37566994]
  • Muhammad Arslan Ahmad, Sadaf Chaudhary, Xu Deng, Mumtaz Cheema, Rabia Javed. Nano-stevia interaction: Past, present, and future. Plant physiology and biochemistry : PPB. 2023 Aug; 201(?):107807. doi: 10.1016/j.plaphy.2023.107807. [PMID: 37311291]
  • Takehiro Watanabe, Kohki Fujikawa, Soichiro Urai, Kazunari Iwaki, Tadayoshi Hirai, Katsuro Miyagawa, Hiroshi Uratani, Tohru Yamagaki, Koji Nagao, Yoshiaki Yokoo, Keiko Shimamoto. Identification, Chemical Synthesis, and Sweetness Evaluation of Rhamnose or Xylose Containing Steviol Glycosides of Stevia (Stevia rebaudiana) Leaves. Journal of agricultural and food chemistry. 2023 Jul; ?(?):. doi: 10.1021/acs.jafc.3c01753. [PMID: 37432401]
  • Yuping Li, Yuan Qiu, Xin Xu, Ming Luo. Genome-wide identification of SrbHLH transcription factors highlights its potential role in rebaudioside A (RA) biosynthesis in Stevia rebaudiana. BMC plant biology. 2023 Jul; 23(1):352. doi: 10.1186/s12870-023-04353-1. [PMID: 37415121]
  • Krishnagowdu Saravanan, Nandakumar Vidya, Jayachandran Halka, Ravichandran Priyanka Preethi, Chinnaswamy Appunu, Ramalingam Radhakrishnan, Muthukrishnan Arun. Exogenous application of stevioside enhances root growth promotion in soybean (Glycine max (L.) Merrill). Plant physiology and biochemistry : PPB. 2023 Jul; 201(?):107881. doi: 10.1016/j.plaphy.2023.107881. [PMID: 37437344]
  • Yunxiang Bai, Beibei Liu, Jiachen Li, Minghui Li, Zheng Yao, Liangliang Dong, Dewei Rao, Peng Zhang, Xingzhong Cao, Luis Francisco Villalobos, Chunfang Zhang, Quan-Fu An, Menachem Elimelech. Microstructure optimization of bioderived polyester nanofilms for antibiotic desalination via nanofiltration. Science advances. 2023 May; 9(18):eadg6134. doi: 10.1126/sciadv.adg6134. [PMID: 37146143]
  • Vasile Coman, Violeta-Florina Scurtu, Cristina Coman, Doina Clapa, Ștefania D Iancu, Nicolae Leopold, Loredana-Florina Leopold. Effects of polystyrene nanoplastics exposure on in vitro-grown Stevia rebaudiana plants. Plant physiology and biochemistry : PPB. 2023 Apr; 197(?):107634. doi: 10.1016/j.plaphy.2023.03.011. [PMID: 36965317]
  • Alireza S Tehranian, Hossein Askari, Hassan Rezadoost. The effect of alginate as an elicitor on transcription of steviol glycosides biosynthesis pathway related key genes and sweeteners content in in vitro cultured Stevia rebaudiana. Molecular biology reports. 2023 Mar; 50(3):2283-2291. doi: 10.1007/s11033-022-07906-z. [PMID: 36576674]
  • Dariush Ramezan, Yusuf Farrokhzad, Ali Mokhtassi-Bidgoli, Mojtaba Rasouli-Alamuti. Multi-walled carbon nanotubes interact with light intensity to affect morpho-biochemical, nutrient uptake, DNA damage, and secondary metabolism of Stevia rebaudiana. Environmental science and pollution research international. 2023 Mar; 30(13):36915-36927. doi: 10.1007/s11356-022-24757-0. [PMID: 36550247]
  • Tulay Ozcan, Ezgi Eroglu. In vitro fermentation assay on the bifidogenic effect of steviol glycosides of Stevia rebaudiana plant for the development of dietetic novel products. Preparative biochemistry & biotechnology. 2023 Jan; ?(?):1-10. doi: 10.1080/10826068.2023.2169935. [PMID: 36709420]
  • Nazima Nasrullah, Javed Ahmad, Monica Saifi, Irum Gul Shah, Umara Nissar, Syed Naved Quadri, Kudsiya Ashrafi, Malik Zainul Abdin. Enhancement of diterpenoid steviol glycosides by co-overexpressing SrKO and SrUGT76G1 genes in Stevia rebaudiana Bertoni. PloS one. 2023; 18(2):e0260085. doi: 10.1371/journal.pone.0260085. [PMID: 36745615]
  • Vartika Srivastava, Rakhi Chaturvedi. An interdisciplinary approach towards sustainable and higher steviol glycoside production from in vitro cultures of Stevia rebaudiana. Journal of biotechnology. 2022 Nov; 358(?):76-91. doi: 10.1016/j.jbiotec.2022.08.018. [PMID: 36075450]
  • Sherien H Abdallah, Nada M Mostafa, Marwa Abd El Hameed Mohamed, Ahmed S Nada, Abdel Nasser B Singab. UPLC-ESI-MS/MS profiling and hepatoprotective activities of Stevia leaves extract, butanol fraction and stevioside against radiation-induced toxicity in rats. Natural product research. 2022 Nov; 36(21):5619-5625. doi: 10.1080/14786419.2021.2015594. [PMID: 34894905]
  • Ashraf Elsayed, Amal M Abdelsattar, Yasmin M Heikal, Mohamed A El-Esawi. Synergistic effects of Azospirillum brasilense and Bacillus cereus on plant growth, biochemical attributes and molecular genetic regulation of steviol glycosides biosynthetic genes in Stevia rebaudiana. Plant physiology and biochemistry : PPB. 2022 Oct; 189(?):24-34. doi: 10.1016/j.plaphy.2022.08.016. [PMID: 36041365]
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