(Chloromethyl)oxirane (BioDeep_00000009903)
Secondary id: BioDeep_00001871681
human metabolite
代谢物信息卡片
(RS)-3-Chloro-1,2-epoxypropane
化学式: C3H5ClO (92.0029)
中文名称: 环氧氯丙烷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(O1)CCl
InChI: InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2
描述信息
(Chloromethyl)oxirane is used for cross-linking dextrose units in food starc
It is used for cross-linking dextrose units in food starch.
同义名列表
51 个代谢物同义名
(RS)-3-Chloro-1,2-epoxypropane; (+/-)-2-(chloromethyl)oxirane; (Chloromethyl)ethylene oxide; 3-Chloro-1,2-propylene oxide; Epichlorohydrin, (+-)-isomer; Epichlorohydrin, (S)-isomer; gamma-Chloropropylene oxide; (DL)-alpha-Epichlorohydrin; Chloro-1,2-propylene oxide; 1-Chloro-2,3-epoxy propone; 1-Chloro-2,3-epoxy-propane; 1,2-Epoxy-3-chloropropane; 3-Chloropropene-1,2-oxide; 1-Chloro-2,3-epoxypropane; 3-Chloro-1,2-epoxypropane; 3-Chloro-propylene oxide; Glycerol epichlorohydrin; 2,3-Epoxypropyl chloride; 2-(Chloromethyl)-oxirane; Γ-chloropropylene oxide; Chloro-1,2-epoxypropane; 3-Chloropropylene oxide; Chloropropene-1,2-oxide; Chloro-2,3-epoxypropane; g-Chloropropylene oxide; 2-(Chloromethyl)oxirane; Glycerol epichlorhydrin; (Chloromethyl)-oxirane; 3-Chloropropyl epoxide; alpha-Epichlorohydrin; (+/-)-epichlorohydrin; Epoxy-3-chloropropane; (Chloromethyl)oxirane; Chloropropylene oxide; Allyl chloride oxide; DL-a-Epichlorohydrin; Epoxypropyl chloride; Chloropropyl epoxide; Chloromethyloxirane; Glycidyl chloride; a-Epichlorohydrin; Α-epichlorohydrin; Epi-chlorohydrin; Epichlorophydrin; Epichloorhydrine; Epichlorhydrine; Chloropropylene; EPICHLOROHYDRIN; Epichlorhydrin; Epichlorohydrin; Epichlorohydrin
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:37144
- KEGG: C14449
- PubChem: 7835
- HMDB: HMDB0034232
- Metlin: METLIN70071
- ChEMBL: CHEMBL1421613
- Wikipedia: Epichlorohydrin
- MeSH: Epichlorohydrin
- foodb: FDB012543
- chemspider: 13837112
- CAS: 13403-37-7
- CAS: 9009-12-5
- CAS: 106-89-8
- PMhub: MS000023724
- PubChem: 17395449
- NIKKAJI: J4.037A
- KNApSAcK: 37144
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Current opinion in pharmacology.
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Molecular pharmacology.
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Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2008 Apr; 12(2):126-32. doi:
10.1111/j.1744-9987.2008.00557.x. [PMID: 18387160] - Burcu Okutucu, Figen Zihnioglu, Azmi Telefoncu. Shell-core imprinted polyacrylamide crosslinked chitosan for albumin removal from plasma.
Journal of biomedical materials research. Part A.
2008 Mar; 84(3):842-5. doi:
10.1002/jbm.a.31714. [PMID: 18080312] - Andrew J Percy, Jürgen Gailer. Methylated trivalent arsenic-glutathione complexes are more stable than their arsenite analog.
Bioinorganic chemistry and applications.
2008; ?(?):539082. doi:
10.1155/2008/539082. [PMID: 18509491] - Satoko Uegaki, Atsushi Tanaka, Yosuke Mori, Hiroko Kodama, Toshio Fukusato, Hajime Takikawa. Successful treatment with colestimide for a bout of cholestasis in a Japanese patient with benign recurrent intrahepatic cholestasis caused by ATP8B1 mutation.
Internal medicine (Tokyo, Japan).
2008; 47(7):599-602. doi:
10.2169/internalmedicine.47.0534. [PMID: 18379143] - I V Kudaeva, L A Budarina, L B Masnavieva. [Patterns of biochemical disorders under exposure to neurotoxic chemicals varying in nature].
Meditsina truda i promyshlennaia ekologiia.
2008; ?(8):7-12. doi:
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Meditsina truda i promyshlennaia ekologiia.
2008; ?(1):17-24. doi:
". [PMID: 18354926] - Tatsuya Suzuki, Kenzo Oba, Yoshimasa Igari, Noriaki Matsumura, Kentaro Watanabe, Shoko Futami-Suda, Hiroko Yasuoka, Motoshi Ouchi, Kazunari Suzuki, Yoshiaki Kigawa, Hiroshi Nakano. Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1 (7-36) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.
2007 Oct; 74(5):338-43. doi:
10.1272/jnms.74.338. [PMID: 17965527] - Kishore B Chalasani, Gregory J Russell-Jones, Akhlesh K Jain, Prakash V Diwan, Sanjay K Jain. Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society.
2007 Sep; 122(2):141-50. doi:
10.1016/j.jconrel.2007.05.019. [PMID: 17707540] - Akhmad Sabarudin, Narong Lenghor, Mitsuko Oshima, Lukman Hakim, Toshio Takayanagi, Yun-Hua Gao, Shoji Motomizu. Sequential-injection on-line preconcentration using chitosan resin functionalized with 2-amino-5-hydroxy benzoic acid for the determination of trace elements in environmental water samples by inductively coupled plasma-atomic emission spectrometry.
Talanta.
2007 Jul; 72(5):1609-17. doi:
10.1016/j.talanta.2007.01.024. [PMID: 19071805] - Norimasa Tamehiro, Yukari Shigemoto-Mogami, Tomoshi Kakeya, Kei-Ichiro Okuhira, Kazuhiro Suzuki, Ryuichiro Sato, Taku Nagao, Tomoko Nishimaki-Mogami. Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.
The Journal of biological chemistry.
2007 Jul; 282(29):21090-9. doi:
10.1074/jbc.m701228200. [PMID: 17526932] - Nobuya Haramaki, Hisao Ikeda, Katsuhiko Takenaka, Atsushi Katoh, Ryo Sugano, Sho-ichi Yamagishi, Hidehiro Matsuoka, Tsutomu Imaizumi. Fluvastatin alters platelet aggregability in patients with hypercholesterolemia: possible improvement of intraplatelet redox imbalance via HMG-CoA reductase.
Arteriosclerosis, thrombosis, and vascular biology.
2007 Jun; 27(6):1471-7. doi:
10.1161/atvbaha.106.128793. [PMID: 17379842] - Elinor Scott, Francisc Peter, Johan Sanders. Biomass in the manufacture of industrial products--the use of proteins and amino acids.
Applied microbiology and biotechnology.
2007 Jun; 75(4):751-62. doi:
10.1007/s00253-007-0932-x. [PMID: 17387469] - Un-jun Hyoung, Yun-jung Yang, Su-kyoung Kwon, Jae-hyoung Yoo, Soon-chul Myoung, Sae-chul Kim, Yeon-pyo Hong. Developmental toxicity by exposure to bisphenol A diglycidyl ether during gestation and lactation period in Sprague-Dawley male rats.
Journal of preventive medicine and public health = Yebang Uihakhoe chi.
2007 Mar; 40(2):155-61. doi:
10.3961/jpmph.2007.40.2.155. [PMID: 17426428] - Kishore B Chalasani, G J Russell-Jones, Sarath K Yandrapu, Prakash V Diwan, Sanjay K Jain. A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin.
Journal of controlled release : official journal of the Controlled Release Society.
2007 Feb; 117(3):421-9. doi:
10.1016/j.jconrel.2006.12.003. [PMID: 17239471] - Tadashi Yamakawa, Tatsuro Takano, Hirotoshi Utsunomiya, Kazuaki Kadonosono, Atushi Okamura. Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hypercholesterolemia.
Endocrine journal.
2007 Feb; 54(1):53-8. doi:
10.1507/endocrj.k05-098. [PMID: 17102570] - Harold Bays, Peter H Jones. Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.
Vascular health and risk management.
2007; 3(5):733-42. doi:
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Archives of toxicology.
2006 Nov; 80(11):748-55. doi:
10.1007/s00204-006-0121-1. [PMID: 16783546] - Tatsuya Suzuki, Kenzo Oba, Shoko Futami, Kazunari Suzuki, Motoshi Ouchi, Yoshimasa Igari, Noriaki Matsumura, Kentaro Watanabe, Yoshiaki Kigawa, Hiroshi Nakano. Blood glucose-lowering activity of colestimide in patients with type 2 diabetes and hypercholesterolemia: a case-control study comparing colestimide with acarbose.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.
2006 Oct; 73(5):277-84. doi:
10.1272/jnms.73.277. [PMID: 17106179] - Renqiang Li, Fengyi Jiang, Xiaofen Zhang, Yao Chen, Ling Fang. Immobilized hemin affinity chromatography as a probe for proteins having potentiality to bind with heme.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Aug; 840(1):63-8. doi:
10.1016/j.jchromb.2006.04.035. [PMID: 16737855] - T S Anirudhan, B F Noeline, D M Manohar. Phosphate removal from wastewaters using a weak anion exchanger prepared from a lignocellulosic residue.
Environmental science & technology.
2006 Apr; 40(8):2740-5. doi:
10.1021/es052070h. [PMID: 16683617] - Ryh-Yaw Hsieh, Hsuan-Ang Tsai, Mei-Jywan Syu. Designing a molecularly imprinted polymer as an artificial receptor for the specific recognition of creatinine in serums.
Biomaterials.
2006 Mar; 27(9):2083-9. doi:
10.1016/j.biomaterials.2005.09.024. [PMID: 16236356] - Helena Gylling, Tatu A Miettinen. Drug-induced effects on cholesterol catabolism and bile acids.
Current opinion in investigational drugs (London, England : 2000).
2006 Mar; 7(3):214-8. doi:
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In vivo (Athens, Greece).
2005 Nov; 19(6):1029-33. doi:
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Biochimica et biophysica acta.
2005 Aug; 1725(1):10-8. doi:
10.1016/j.bbagen.2005.06.004. [PMID: 16023787] - Ryo Sugano, Hidehiro Matsuoka, Nobuya Haramaki, Hidekazu Umei, Eiko Murase, Kei Fukami, Shuji Iida, Hisao Ikeda, Tsutomu Imaizumi. Polymorphonuclear leukocytes may impair endothelial function: results of crossover randomized study of lipid-lowering therapies.
Arteriosclerosis, thrombosis, and vascular biology.
2005 Jun; 25(6):1262-7. doi:
10.1161/01.atv.0000163842.91226.ba. [PMID: 15790932] - Hsuan-Ang Tsai, Mei-Jywan Syu. Synthesis of creatinine-imprinted poly(beta-cyclodextrin) for the specific binding of creatinine.
Biomaterials.
2005 May; 26(15):2759-66. doi:
10.1016/j.biomaterials.2004.07.037. [PMID: 15585280] - Masa-aki Kawashiri, Toshinori Higashikata, Atsushi Nohara, Junji Kobayashi, Akihiro Inazu, Junji Koizumi, Hiroshi Mabuchi. Efficacy of colestimide coadministered with atorvastatin in japanese patients with heterozygous familial hypercholesterolemia (FH).
Circulation journal : official journal of the Japanese Circulation Society.
2005 May; 69(5):515-20. doi:
10.1253/circj.69.515. [PMID: 15849435] - Rui Zhao, Jia Luo, Dihua Shangguan, Guoquan Liu. A novel matrix for high performance affinity chromatography and its application in the purification of antithrombin III.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Feb; 816(1-2):175-81. doi:
10.1016/j.jchromb.2004.11.030. [PMID: 15664348] - Fumihiko Kushiya, Hideo Wada, Kinue Ooi, Yuko Sakurai, Akane Sakaguchi, Maki Noda, Yasunori Abe, Takahiro Nakasaki, Tetsuya Tsukada, Hiroshi Shiku, Tsutomu Nobori. Effects of atorvastatin on serum lipids, lipoproteins, and hemostasis.
American journal of hematology.
2005 Jan; 78(1):1-6. doi:
10.1002/ajh.20191. [PMID: 15609278] - Hidehisa Sasaki, Saburo Kanai, Tomokazu Oyama, Yoh Miyashita, Kohji Shirai. Usefulness of preheparin lipoprotein lipase mass as a parameter for predicting the efficacy of colestimide.
Journal of atherosclerosis and thrombosis.
2005; 12(4):218-24. doi:
10.5551/jat.12.218. [PMID: 16141626] - Makoto Kimura, Tomoko Masuda, Koji Yamada, Masaki Mitani, Nobuo Kubota, Nobuyuki Kawakatsu, Kenichi Kishii, Masato Inazu, Yuji Kiuchi, Katsuji Oguchi, Takayuki Namiki. Efficient asymmetric syntheses, determination of absolute configurations and biological activities of 1-[4,4-bis(4-fluorophenyl)butyl]-4-[2-hydroxy-3-(phenylamino)propyl]piperazine as a novel potent dopamine uptake inhibitor in the central nervous system.
Bioorganic & medicinal chemistry.
2004 Jun; 12(11):3069-78. doi:
10.1016/j.bmc.2004.02.041. [PMID: 15142566] - Guoqi Fu, Haofeng Yu, Zhi Yuan, Bin Liu, Bin Shen, Binglin He. Chitosan adsorbents carrying amino acids for selective removal of low density lipoprotein.
Artificial cells, blood substitutes, and immobilization biotechnology.
2004 May; 32(2):303-13. doi:
10.1081/bio-120037835. [PMID: 15274435] - Xiangling He, Tianwei Tan, Bingze Xu, Jan-Christer Janson. Separation and purification of puerarin using beta-cyclodextrin-coupled agarose gel media.
Journal of chromatography. A.
2004 Jan; 1022(1-2):77-82. doi:
10.1016/j.chroma.2003.09.045. [PMID: 14753773] - Eli Ruckenstein, Wei Guo. Cellulose and glass fiber affinity membranes for the chromatographic separation of biomolecules.
Biotechnology progress.
2004 Jan; 20(1):13-25. doi:
10.1021/bp030055f. [PMID: 14763818] - Toshiyuki Date, Takashi Shigematsu, Yoshiteru Kawashita, Nobuyoshi Satake, Kyoko Morita. Colestimide can be used as a phosphate binder to treat uraemia in end-stage renal disease patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2003 Jun; 18 Suppl 3(?):iii90-3. doi:
10.1093/ndt/gfg1023. [PMID: 12771311] - Masahiko Okada, Ken-ichi Matsumoto, Takeshi Niki, Takahiro Taira, Sanae M M Iguchi-Ariga, Hiroyoshi Ariga. DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice.
Biological & pharmaceutical bulletin.
2002 Jul; 25(7):853-6. doi:
10.1248/bpb.25.853. [PMID: 12132656] - Keiichi Miyamoto, Katsuyuki Sugihara, Yasunori Abe, Tsutomu Nobori, Masayuki Tokita, Takashi Komai. Novel plasma-separation dilayer gellan-gellan-sulfate adsorber for direct removal of extra domain A containing fibronectin from the blood of rheumatoid arthritis patients.
International journal of biological macromolecules.
2002 Jun; 30(3-4):197-204. doi:
10.1016/s0141-8130(02)00020-x. [PMID: 12063122] - Deling Kong, Wolfgang Schuett, Jun Dai, Siegfred Kunkel, Manfred Holtz, Ryo Yamada, Yaoting Yu, Horst Klinkmann. Development of cellulose-DNA immunoadsorbent.
Artificial organs.
2002 Feb; 26(2):200-8. doi:
10.1046/j.1525-1594.2002.06721.x. [PMID: 11879250] - H Takikawa, T Ogasawara, A Sato, M Ohashi, Y Hasegawa, M Hojo. Effect of colestimide on intestinal absorption of ursodeoxycholic acid in men.
International journal of clinical pharmacology and therapeutics.
2001 Dec; 39(12):558-60. doi:
10.5414/cpp39558. [PMID: 11770838] - C Alvarez, M Strumia, H Bertorello. Synthesis and characterization of a biospecific adsorbent containing bovine serum albumin as a ligand and its use for bilirubin retention.
Journal of biochemical and biophysical methods.
2001 Oct; 49(1-3):649-56. doi:
10.1016/s0165-022x(01)00226-3. [PMID: 11694308] - H W Kuo, Y S Huang, J C Lo, T J Cheng, M J Wu. Exposure to solvents in a synthetic leather manufacturing plant.
International archives of occupational and environmental health.
2000 May; 73(4):275-80. doi:
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Carcinogenesis.
2000 Feb; 21(2):275-80. doi:
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