Bisphenol C (BioDeep_00000009777)

 

Secondary id: BioDeep_00001874632

human metabolite blood metabolite


代谢物信息卡片


4-[2,2-dichloro-1-(4-hydroxyphenyl)ethenyl]phenol

化学式: C14H10Cl2O2 (280.0058)
中文名称: 2,2-双(4-羟苯基)-1,1-二氯乙烯, 双酚 C
谱图信息: 最多检出来源 Homo sapiens(blood) 97.54%

分子结构信息

SMILES: C1=CC(=CC=C1C(=C(Cl)Cl)C2=CC=C(C=C2)O)O
InChI: InChI=1S/C14H10Cl2O2/c15-14(16)13(9-1-5-11(17)6-2-9)10-3-7-12(18)8-4-10/h1-8,17-18H



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AR, CAT, ESR1, GPER1, MTOR, PHB1, RPS6, TGFB1, TYR, YAP1
Peripheral membrane protein 3 ESR1, HSD17B6, MTOR
Endoplasmic reticulum membrane 3 GPER1, MTOR, SPP1
Mitochondrion membrane 1 GPER1
Nucleus 10 AR, ESR1, ESRRG, GPER1, MTOR, PHB1, RPS6, TCF4, TGFB1, YAP1
cytosol 7 AR, CAT, ESR1, GPER1, MTOR, RPS6, YAP1
dendrite 3 GPER1, MTOR, RPS6
mitochondrial membrane 1 GPER1
phagocytic vesicle 1 MTOR
trans-Golgi network 1 GPER1
nucleoplasm 9 AR, ESR1, ESRRG, GPER1, MTOR, PHB1, RPS6, TCF4, YAP1
Cell membrane 5 ESR1, PHB1, SPP1, TNF, YAP1
Cytoplasmic side 2 ESR1, MTOR
Cell projection, axon 1 GPER1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 2 GPER1, SPP1
Golgi apparatus membrane 2 GPER1, MTOR
cell junction 1 YAP1
cell surface 3 PHB1, TGFB1, TNF
dendritic shaft 1 GPER1
glutamatergic synapse 1 LRRC4C
Golgi apparatus 3 ESR1, GPER1, SPP1
Golgi membrane 2 GPER1, MTOR
lysosomal membrane 1 MTOR
mitochondrial inner membrane 1 PHB1
neuronal cell body 2 TGFB1, TNF
presynaptic membrane 1 GPER1
Lysosome 2 MTOR, TYR
plasma membrane 8 AR, ESR1, GPER1, LRRC4C, PHB1, SPP1, TGFB1, TNF
presynaptic active zone 1 GPER1
Membrane 9 AR, CAT, ESR1, GPER1, LRRC4C, MTOR, PHB1, RPS6, YAP1
axon 2 GPER1, TGFB1
extracellular exosome 3 CAT, PHB1, SPP1
Lysosome membrane 1 MTOR
Lumenal side 1 HSD17B6
endoplasmic reticulum 3 GPER1, HSD17B6, RPS6
extracellular space 5 IGFBP4, LRRC4C, SPP1, TGFB1, TNF
perinuclear region of cytoplasm 4 GPER1, RPS6, SPP1, TYR
Schaffer collateral - CA1 synapse 1 LRRC4C
Cell junction, tight junction 1 YAP1
bicellular tight junction 1 YAP1
mitochondrion 2 CAT, PHB1
protein-containing complex 3 AR, CAT, ESR1
intracellular membrane-bounded organelle 4 CAT, GPER1, HSD17B6, TYR
Microsome membrane 2 HSD17B6, MTOR
postsynaptic density 1 GPER1
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 LRRC4C, TYR
Secreted 2 SPP1, TGFB1
extracellular region 5 CAT, IGFBP4, SPP1, TGFB1, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
hippocampal mossy fiber to CA3 synapse 1 GPER1
mitochondrial matrix 1 CAT
transcription regulator complex 2 ESR1, TCF4
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 TGFB1
nucleolus 2 GPER1, RPS6
Melanosome membrane 1 TYR
Early endosome 2 GPER1, PHB1
cell-cell junction 1 YAP1
Golgi-associated vesicle 1 TYR
recycling endosome 2 GPER1, TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 PHB1
Membrane raft 1 TNF
focal adhesion 1 CAT
extracellular matrix 1 TGFB1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 2 MTOR, TCF4
PML body 2 MTOR, TCF4
collagen-containing extracellular matrix 1 TGFB1
secretory granule 1 TGFB1
nuclear speck 1 AR
Postsynaptic cell membrane 1 LRRC4C
chromatin 4 AR, ESR1, ESRRG, TCF4
cell projection 1 SPP1
phagocytic cup 1 TNF
cytoplasmic ribonucleoprotein granule 1 RPS6
Nucleus, nucleolus 1 RPS6
blood microparticle 1 TGFB1
nuclear envelope 2 GPER1, MTOR
Endomembrane system 1 MTOR
female germ cell nucleus 1 YAP1
Cytoplasmic vesicle membrane 1 GPER1
Cell projection, dendrite 1 GPER1
Melanosome 1 TYR
euchromatin 1 ESR1
cell body 1 RPS6
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
Golgi lumen 1 TGFB1
endoplasmic reticulum lumen 2 IGFBP4, SPP1
platelet alpha granule lumen 1 TGFB1
axon terminus 1 GPER1
beta-catenin-TCF complex 1 TCF4
small-subunit processome 1 RPS6
postsynaptic density membrane 1 LRRC4C
ribonucleoprotein complex 1 RPS6
[Isoform 1]: Nucleus 1 ESR1
protein-DNA complex 1 TCF4
keratin filament 1 GPER1
Cytoplasmic vesicle, phagosome 1 MTOR
cytosolic ribosome 1 RPS6
dendritic spine head 1 GPER1
Cell projection, dendritic spine membrane 1 GPER1
dendritic spine membrane 1 GPER1
ribosome 1 RPS6
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix 1 TGFB1
[Transforming growth factor beta-1]: Secreted 1 TGFB1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
cytosolic small ribosomal subunit 1 RPS6
beta-catenin-TCF7L2 complex 1 TCF4
TEAD-YAP complex 1 YAP1
mitochondrial prohibitin complex 1 PHB1
small ribosomal subunit 1 RPS6
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
catenin-TCF7L2 complex 1 TCF4


文献列表

  • Pensiri Buacheen, Jirarat Karinchai, Natchapon Kammasit, Piya Temviriyanukul, Chutikarn Butkinaree, Santi Watthana, Ariyaphong Wongnoppavich, Arisa Imsumran, Pornsiri Pitchakarn. Protective effect of Anoectochilus burmannicus extracts and its active compound, kinsenoside on adipocyte differentiation induced by benzyl butyl phthalate and bisphenol A. Scientific reports. 2023 Feb; 13(1):2939. doi: 10.1038/s41598-023-30227-5. [PMID: 36806746]
  • Ying Han, Yuxuan Liu, Mingxin Wang, Yingang Xue. Effects of BPZ, BPC, BPF, and BPS Exposure on Adult Zebrafish (Danio rerio): Accumulation, Oxidative Stress, and Gene Expression. International journal of environmental research and public health. 2022 11; 19(23):. doi: 10.3390/ijerph192315784. [PMID: 36497860]
  • Justyna Milczarek-Banach, Dominik Rachoń, Tomasz Bednarczuk, Katarzyna Myśliwiec-Czajka, Andrzej Wasik, Piotr Miśkiewicz. Exposure to Bisphenol A Analogs and the Thyroid Function and Volume in Women of Reproductive Age-Cross-Sectional Study. Frontiers in endocrinology. 2020; 11(?):587252. doi: 10.3389/fendo.2020.587252. [PMID: 33542704]